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The map label for this gene is fixC [H]

Identifier: 86748111

GI number: 86748111

Start: 1131485

End: 1132792

Strand: Direct

Name: fixC [H]

Synonym: RPB_0986

Alternate gene names: 86748111

Gene position: 1131485-1132792 (Clockwise)

Preceding gene: 86748110

Following gene: 86748112

Centisome position: 21.22

GC content: 63.3

Gene sequence:

>1308_bases
ATGATCGAGGAACGTTTCGACGCGATCGTGGTCGGCGCCGGCATGGCCGGAAACGCCGCCGCGCTGACGATGGCCAAACG
CGGCATGAAGGTGCTGCAGATCGAGCGCGGTGAATATCCGGGCTCGAAGAACGTCCAGGGCGCGATTCTCTACGCCGACA
TGCTGGAGAAGCTGGTGCCGAACTTCCGCGAGGACGCGCCGCTCGAGCGTCATCTGGTGGAGCAGCGGTTCTGGATGATG
GACGAGCGCTCGCACACCGGGCTGCATTATCGCTCGGACGATTTCAACGAAGAGAAGCCGAACCGCTACACCATCATCCG
CGCGCAGTTCGACAAATGGTTCTCCAGCCAGGCGCAGGAAGCCGGCGCCATCGTGCTGTGCGAGACCACCGTCAAGGAAC
TGGTGAAGGACGCCTATGGCAAGGTGATCGGCGTGATCACCGACCGCGAGGGCGGCGAGGTCCATGCCGACGTCGTGGTG
CTGGCCGAGGGCGTCAACGGCCTGCTCGGCACCAAGGCGGATCTGCGCGAGCGGCCGTCGCCCGACAAGGTCGCGCTGGC
GGTGAAGGAAATGCACTTCCTGCCCCGCGAGACCATCGAGGCGCGCTTCAACCTCAAGGGCGACGAGGGCGTGGTGATCG
AGGCGGCGGGCACGATCTCCCGCGGCATGACCGGGATGGGCTTCGTCTACGCCAACAAGGAATCGGTGTCGGTCGGCATC
GGCTGTCTGGTCGCCGATTTCCAGAAATCCGGCGAGACGCCCTACGATCTGCTCGAGCGCTTCAAGAAGCATCCCTCGAT
CGCGCCGCTGATCGAAGGCTCCGAGGTCAAGGAATATGCCGGCCATCTGATTCCCGAGGGCGGCTACAAGGCGATCCCGC
AGCTCTATGGCGACGGCTGGGTGGTGGTCGGCGACGCTGCGCAGCTCAACAACGCGCTGCATCGCGAAGGCTCGAATCTG
GCGATGACCTCCGGCCGGATCGCCGGCGAGGCGATCTTCCAGGTCAAGTCGCGCAAGGATCCGATGACCAAGGAGAATCT
GGCGCTCTACAAGAAGATGCTGGACGAGTCCTTCGTCATCAAGGATCTGAAGAAGTACAAGGATATGCCGGATCTGCTGC
ACATCCAGTCGCAGAACTTCTTCCTGACCTATCCGCAGCTCATCAACAAGGCGCTGCAGAACTTCGTGCGGGTCGACGGC
ACGCCGAAGGTCGACAAGGAGAAGGTGACGATCAGATCGTTCGTGTCGGCGCGATCCTGGGCGGGCCTGTTCGGCGACGC
CTTCCGCTTCGCGCGGGCATGGCGGTGA

Upstream 100 bases:

>100_bases
CACCGACGCGATCCGCCTGCTGCCGGCGCTGACCGAAGCATTCCGCAAGCGGCTGTCGCCGCACACCCGCGACCGCATCG
CGAGCTAACAGGAGTTCACC

Downstream 100 bases:

>100_bases
ACGGCGACGGCGACGAACTCAAACGCGGAGAGCAACAATGACGGTGGAAGCCCCCATTCGGGTCGAGGACAAGCTGTTCC
AGAACCGCTATCTGGTCGAC

Product: electron-transferring-flavoprotein dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MIEERFDAIVVGAGMAGNAAALTMAKRGMKVLQIERGEYPGSKNVQGAILYADMLEKLVPNFREDAPLERHLVEQRFWMM
DERSHTGLHYRSDDFNEEKPNRYTIIRAQFDKWFSSQAQEAGAIVLCETTVKELVKDAYGKVIGVITDREGGEVHADVVV
LAEGVNGLLGTKADLRERPSPDKVALAVKEMHFLPRETIEARFNLKGDEGVVIEAAGTISRGMTGMGFVYANKESVSVGI
GCLVADFQKSGETPYDLLERFKKHPSIAPLIEGSEVKEYAGHLIPEGGYKAIPQLYGDGWVVVGDAAQLNNALHREGSNL
AMTSGRIAGEAIFQVKSRKDPMTKENLALYKKMLDESFVIKDLKKYKDMPDLLHIQSQNFFLTYPQLINKALQNFVRVDG
TPKVDKEKVTIRSFVSARSWAGLFGDAFRFARAWR

Sequences:

>Translated_435_residues
MIEERFDAIVVGAGMAGNAAALTMAKRGMKVLQIERGEYPGSKNVQGAILYADMLEKLVPNFREDAPLERHLVEQRFWMM
DERSHTGLHYRSDDFNEEKPNRYTIIRAQFDKWFSSQAQEAGAIVLCETTVKELVKDAYGKVIGVITDREGGEVHADVVV
LAEGVNGLLGTKADLRERPSPDKVALAVKEMHFLPRETIEARFNLKGDEGVVIEAAGTISRGMTGMGFVYANKESVSVGI
GCLVADFQKSGETPYDLLERFKKHPSIAPLIEGSEVKEYAGHLIPEGGYKAIPQLYGDGWVVVGDAAQLNNALHREGSNL
AMTSGRIAGEAIFQVKSRKDPMTKENLALYKKMLDESFVIKDLKKYKDMPDLLHIQSQNFFLTYPQLINKALQNFVRVDG
TPKVDKEKVTIRSFVSARSWAGLFGDAFRFARAWR
>Mature_435_residues
MIEERFDAIVVGAGMAGNAAALTMAKRGMKVLQIERGEYPGSKNVQGAILYADMLEKLVPNFREDAPLERHLVEQRFWMM
DERSHTGLHYRSDDFNEEKPNRYTIIRAQFDKWFSSQAQEAGAIVLCETTVKELVKDAYGKVIGVITDREGGEVHADVVV
LAEGVNGLLGTKADLRERPSPDKVALAVKEMHFLPRETIEARFNLKGDEGVVIEAAGTISRGMTGMGFVYANKESVSVGI
GCLVADFQKSGETPYDLLERFKKHPSIAPLIEGSEVKEYAGHLIPEGGYKAIPQLYGDGWVVVGDAAQLNNALHREGSNL
AMTSGRIAGEAIFQVKSRKDPMTKENLALYKKMLDESFVIKDLKKYKDMPDLLHIQSQNFFLTYPQLINKALQNFVRVDG
TPKVDKEKVTIRSFVSARSWAGLFGDAFRFARAWR

Specific function: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from fixA/fixB and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=402, Percent_Identity=25.8706467661692, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI1786227, Length=412, Percent_Identity=37.1359223300971, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1787991, Length=411, Percent_Identity=37.956204379562, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI87082155, Length=376, Percent_Identity=33.7765957446808, Blast_Score=219, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI25144720, Length=394, Percent_Identity=25.3807106598985, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324932, Length=364, Percent_Identity=27.1978021978022, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24652256, Length=401, Percent_Identity=24.4389027431421, Blast_Score=106, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.5.5.-

Molecular weight: Translated: 48497; Mature: 48497

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEERFDAIVVGAGMAGNAAALTMAKRGMKVLQIERGEYPGSKNVQGAILYADMLEKLVP
CCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEHHHHHHHHHCC
NFREDAPLERHLVEQRFWMMDERSHTGLHYRSDDFNEEKPNRYTIIRAQFDKWFSSQAQE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHH
AGAIVLCETTVKELVKDAYGKVIGVITDREGGEVHADVVVLAEGVNGLLGTKADLRERPS
CCEEEEEHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEECCCCCHHCCCHHHHCCCC
PDKVALAVKEMHFLPRETIEARFNLKGDEGVVIEAAGTISRGMTGMGFVYANKESVSVGI
CHHHHHHHHHHHHCCHHHHHHEEECCCCCCEEEEECCCHHCCCCCCEEEEECCCCCEEEH
GCLVADFQKSGETPYDLLERFKKHPSIAPLIEGSEVKEYAGHLIPEGGYKAIPQLYGDGW
HHHEEHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCE
VVVGDAAQLNNALHREGSNLAMTSGRIAGEAIFQVKSRKDPMTKENLALYKKMLDESFVI
EEECCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
KDLKKYKDMPDLLHIQSQNFFLTYPQLINKALQNFVRVDGTPKVDKEKVTIRSFVSARSW
HHHHHHCCCCHHEEECCCCEEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
AGLFGDAFRFARAWR
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MIEERFDAIVVGAGMAGNAAALTMAKRGMKVLQIERGEYPGSKNVQGAILYADMLEKLVP
CCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEHHHHHHHHHCC
NFREDAPLERHLVEQRFWMMDERSHTGLHYRSDDFNEEKPNRYTIIRAQFDKWFSSQAQE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHH
AGAIVLCETTVKELVKDAYGKVIGVITDREGGEVHADVVVLAEGVNGLLGTKADLRERPS
CCEEEEEHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEECCCCCHHCCCHHHHCCCC
PDKVALAVKEMHFLPRETIEARFNLKGDEGVVIEAAGTISRGMTGMGFVYANKESVSVGI
CHHHHHHHHHHHHCCHHHHHHEEECCCCCCEEEEECCCHHCCCCCCEEEEECCCCCEEEH
GCLVADFQKSGETPYDLLERFKKHPSIAPLIEGSEVKEYAGHLIPEGGYKAIPQLYGDGW
HHHEEHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCE
VVVGDAAQLNNALHREGSNLAMTSGRIAGEAIFQVKSRKDPMTKENLALYKKMLDESFVI
EEECCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
KDLKKYKDMPDLLHIQSQNFFLTYPQLINKALQNFVRVDGTPKVDKEKVTIRSFVSARSW
HHHHHHCCCCHHEEECCCCEEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
AGLFGDAFRFARAWR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1850088 [H]