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The map label for this gene is fbp [H]

Identifier: 86748072

GI number: 86748072

Start: 1094940

End: 1095971

Strand: Direct

Name: fbp [H]

Synonym: RPB_0947

Alternate gene names: 86748072

Gene position: 1094940-1095971 (Clockwise)

Preceding gene: 86748071

Following gene: 86748073

Centisome position: 20.54

GC content: 67.54

Gene sequence:

>1032_bases
ATGGATCAGGGTCAGACGTTATCGCGTCTTTTGGACTCTTACGGGACGGACGCGCGCACGCGCGCGGTTGCCGCGGCTGT
CGGCGCGATCGCCGAGGCGTCGATCGAAATCTCCGACCTGATCGGGCAGGGCGCGCTGGCCGGGATCACCGGCGCGGCCC
ATGGCGCGAGCAATGCGGACGGCGACGTCCAGAAGGATCTCGACGTCCGCGCCGAGGCCGCCATCGTCGCGGCGCTGAAG
AACGTTCCCTATGCGGCATTGGCCTCCGAGGAGTCCGACACGCTGCTGATGGGCGATCCGCAGGCACCGATCTCGATCGC
CTACGATCCGCTCGACGGCTCGTCGAATATCGACACCAATATGACGGTCGGGACGATCTTCTCGGTCATTCCGAACGAGC
CCGGGGTGGCGCCGTTCACCGCACCGGGCAGCTGCCAGCTCGCCGCCGGCTTCGTGGTCTACGGGCCGCAGACCTCGCTG
GTGCTGACGCTCGGCGACGGCGTCGACATCTTTACGCTCGACCGCGCCGCGAAGACCTATCGACTGATCCGCGAGCGCGT
CCAGGTGCCGGCCGACACCGCCGAATACGCTATCAACGCCTCCAACCATCGCCACTGGGAGCAGCCGGTGCGCGATTTCG
TCGACGAGTGTCTGGCCGGGACCGACGGTCCGCGCGCCAAGAACTTCAACATGCGCTGGATCGGTTCGCTGGTGGCGGAG
GCCTATCGCATTCTCACCCGCGGTGGCGTGTTCCTGTATCCGGCGGATTCGCGGCCCGGCTACGGCGAAGGCCGGCTGCG
TGTTCTCTACGAGACCCATCCGATGGCATTCGTGATGGAGCAGGCCGGCGGGGCCGCCTCCACCGGCCGCGAACGCGTTC
TCGACGTCGTCGCGAGCACGACCCACCAGCGCTCGCCGCTGATCATGGGGTCGAGTGACAAGGTCCATCGTATCGTCGAG
CTGCACCTCGATCCGGCCGCGGCCTCACGCACAGCGCCGTTGTTCGGGCGCCGCGGCCTGTTCCGGACCTGA

Upstream 100 bases:

>100_bases
GAAAATGAAATTTCTCTTATGCCGTGGTTGAGCCCACAACCCCCGGGTGATGGGCTCGCTGCGACAATTTGGCCGGACGG
CGTGGTTGGGGGTTTAAGGG

Downstream 100 bases:

>100_bases
ACCAAGTCCCCAATTGTTGGAAATGTGAATCCATGTCCCGTAAGCATCCGATCATCTCGATCACCGGCTCCTCCGGCGCC
GGAACGACCTCCGTCAAGCG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MDQGQTLSRLLDSYGTDARTRAVAAAVGAIAEASIEISDLIGQGALAGITGAAHGASNADGDVQKDLDVRAEAAIVAALK
NVPYAALASEESDTLLMGDPQAPISIAYDPLDGSSNIDTNMTVGTIFSVIPNEPGVAPFTAPGSCQLAAGFVVYGPQTSL
VLTLGDGVDIFTLDRAAKTYRLIRERVQVPADTAEYAINASNHRHWEQPVRDFVDECLAGTDGPRAKNFNMRWIGSLVAE
AYRILTRGGVFLYPADSRPGYGEGRLRVLYETHPMAFVMEQAGGAASTGRERVLDVVASTTHQRSPLIMGSSDKVHRIVE
LHLDPAAASRTAPLFGRRGLFRT

Sequences:

>Translated_343_residues
MDQGQTLSRLLDSYGTDARTRAVAAAVGAIAEASIEISDLIGQGALAGITGAAHGASNADGDVQKDLDVRAEAAIVAALK
NVPYAALASEESDTLLMGDPQAPISIAYDPLDGSSNIDTNMTVGTIFSVIPNEPGVAPFTAPGSCQLAAGFVVYGPQTSL
VLTLGDGVDIFTLDRAAKTYRLIRERVQVPADTAEYAINASNHRHWEQPVRDFVDECLAGTDGPRAKNFNMRWIGSLVAE
AYRILTRGGVFLYPADSRPGYGEGRLRVLYETHPMAFVMEQAGGAASTGRERVLDVVASTTHQRSPLIMGSSDKVHRIVE
LHLDPAAASRTAPLFGRRGLFRT
>Mature_343_residues
MDQGQTLSRLLDSYGTDARTRAVAAAVGAIAEASIEISDLIGQGALAGITGAAHGASNADGDVQKDLDVRAEAAIVAALK
NVPYAALASEESDTLLMGDPQAPISIAYDPLDGSSNIDTNMTVGTIFSVIPNEPGVAPFTAPGSCQLAAGFVVYGPQTSL
VLTLGDGVDIFTLDRAAKTYRLIRERVQVPADTAEYAINASNHRHWEQPVRDFVDECLAGTDGPRAKNFNMRWIGSLVAE
AYRILTRGGVFLYPADSRPGYGEGRLRVLYETHPMAFVMEQAGGAASTGRERVLDVVASTTHQRSPLIMGSSDKVHRIVE
LHLDPAAASRTAPLFGRRGLFRT

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=326, Percent_Identity=35.2760736196319, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI16579888, Length=326, Percent_Identity=35.2760736196319, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI22907028, Length=320, Percent_Identity=33.4375, Blast_Score=170, Evalue=2e-42,
Organism=Escherichia coli, GI1790679, Length=308, Percent_Identity=40.2597402597403, Blast_Score=207, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17508131, Length=304, Percent_Identity=36.8421052631579, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6323409, Length=302, Percent_Identity=36.0927152317881, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI19921562, Length=319, Percent_Identity=35.1097178683386, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI45550998, Length=319, Percent_Identity=35.1097178683386, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR020548 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 36410; Mature: 36410

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQGQTLSRLLDSYGTDARTRAVAAAVGAIAEASIEISDLIGQGALAGITGAAHGASNAD
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEHHHHHCCCHHHHCCCCCCCCCCCC
GDVQKDLDVRAEAAIVAALKNVPYAALASEESDTLLMGDPQAPISIAYDPLDGSSNIDTN
CCCHHCCHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCEEEEEECCCCCCCCCCC
MTVGTIFSVIPNEPGVAPFTAPGSCQLAAGFVVYGPQTSLVLTLGDGVDIFTLDRAAKTY
CCHHHHHEECCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCEEEEEHHHHHHH
RLIRERVQVPADTAEYAINASNHRHWEQPVRDFVDECLAGTDGPRAKNFNMRWIGSLVAE
HHHHHHHCCCCCCHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
AYRILTRGGVFLYPADSRPGYGEGRLRVLYETHPMAFVMEQAGGAASTGRERVLDVVAST
HHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHC
THQRSPLIMGSSDKVHRIVELHLDPAAASRTAPLFGRRGLFRT
CCCCCCEEECCCCHHEEEEEEEECCHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDQGQTLSRLLDSYGTDARTRAVAAAVGAIAEASIEISDLIGQGALAGITGAAHGASNAD
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEHHHHHCCCHHHHCCCCCCCCCCCC
GDVQKDLDVRAEAAIVAALKNVPYAALASEESDTLLMGDPQAPISIAYDPLDGSSNIDTN
CCCHHCCHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCEEEEEECCCCCCCCCCC
MTVGTIFSVIPNEPGVAPFTAPGSCQLAAGFVVYGPQTSLVLTLGDGVDIFTLDRAAKTY
CCHHHHHEECCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCEEEEEHHHHHHH
RLIRERVQVPADTAEYAINASNHRHWEQPVRDFVDECLAGTDGPRAKNFNMRWIGSLVAE
HHHHHHHCCCCCCHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
AYRILTRGGVFLYPADSRPGYGEGRLRVLYETHPMAFVMEQAGGAASTGRERVLDVVAST
HHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHC
THQRSPLIMGSSDKVHRIVELHLDPAAASRTAPLFGRRGLFRT
CCCCCCEEECCCCHHEEEEEEEECCHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA