Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 86747787

GI number: 86747787

Start: 745558

End: 746364

Strand: Reverse

Name: uppP

Synonym: RPB_0661

Alternate gene names: 86747787

Gene position: 746364-745558 (Counterclockwise)

Preceding gene: 86747791

Following gene: 86747785

Centisome position: 14.0

GC content: 63.2

Gene sequence:

>807_bases
ATGCTTTCCGATATCATCAGAGCCGTGATTCTCGGCGTGGTCGAGGGTGTCACCGAGTTCCTGCCGGTCTCATCGACCGG
CCATCTGCTGCTGGTGGGGCGATTCTTCAATCTCGGCGAGGGCGATTTCTGGAAGACCTTCGACGTCCTGATCCAGCTCG
GCGCGATCCTCGCGATCCTCGCGCTTTATTTCGCCAAATTGTGGCGAATTGCGCTCGGGATGTTCTCGGATCCGGCGGCG
CAGCGTTTCATCATCGGCGTGCTGGTCGCGTTCCTGCCGGCGGCGGTGATCGGCGCTGCGGCGGGATCCTACATCAAGCT
GTTTCTGTTCAACCCCTGGGTGGTGTGCTTCTCGCTGATCGTCGGCGGCGCCGTCTTGCTGTGGGTCGATCAGCTCGACC
TGAAGCCGCGCCACCATGATGCCACGACGTTCCCGGTGCTGATGTATTTCTACATCGGATGCGCGCAATGCGTGGCGATG
ATCCCCGGCGTGTCACGCTCCGGCGCCAGCATCGTGGCGGCGATGCTGTTCGGCGCCGACAAGCGCGCCGCCGCCGAGTT
CTCGTTCTTTCTGGCGATCCCGACCATGGTCGGCGCCTTCGTGTACGACCTCTACAAGAGCCGCGCCGATCTGACGACCG
ACCACATGACCATCGTGGCGGTCGGCTTCGTGGTGTCGTTCATTACCGCGATCATCGTGGTGAAGACCTTCCTCGGCTAC
GTCACCCGTCACGGCTTCCAGCTGTTCGCGTGGTGGCGCGTCGTCGTCGGCACGCTCGGCCTGATCGCGCTGGCGATGGG
CCGCTGA

Upstream 100 bases:

>100_bases
GCGAGCCGGCTTTCGGCGTATTTTGACGTTGCGGCATGCAATCGAATAGGCGACAAGGTCGCGCCTCTTGCGCGACCGAA
CCCTCCCGGCGGACAATCTC

Downstream 100 bases:

>100_bases
TCGCGGCGCAAAGCCGCGATCGTCACGCGCGGGTCGTCACGCGCGCCTCGTCACGCGTTCTTGCGCGCGAACTGGCCGGT
CTTGCGGAAGCGCCAGAGAT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MLSDIIRAVILGVVEGVTEFLPVSSTGHLLLVGRFFNLGEGDFWKTFDVLIQLGAILAILALYFAKLWRIALGMFSDPAA
QRFIIGVLVAFLPAAVIGAAAGSYIKLFLFNPWVVCFSLIVGGAVLLWVDQLDLKPRHHDATTFPVLMYFYIGCAQCVAM
IPGVSRSGASIVAAMLFGADKRAAAEFSFFLAIPTMVGAFVYDLYKSRADLTTDHMTIVAVGFVVSFITAIIVVKTFLGY
VTRHGFQLFAWWRVVVGTLGLIALAMGR

Sequences:

>Translated_268_residues
MLSDIIRAVILGVVEGVTEFLPVSSTGHLLLVGRFFNLGEGDFWKTFDVLIQLGAILAILALYFAKLWRIALGMFSDPAA
QRFIIGVLVAFLPAAVIGAAAGSYIKLFLFNPWVVCFSLIVGGAVLLWVDQLDLKPRHHDATTFPVLMYFYIGCAQCVAM
IPGVSRSGASIVAAMLFGADKRAAAEFSFFLAIPTMVGAFVYDLYKSRADLTTDHMTIVAVGFVVSFITAIIVVKTFLGY
VTRHGFQLFAWWRVVVGTLGLIALAMGR
>Mature_268_residues
MLSDIIRAVILGVVEGVTEFLPVSSTGHLLLVGRFFNLGEGDFWKTFDVLIQLGAILAILALYFAKLWRIALGMFSDPAA
QRFIIGVLVAFLPAAVIGAAAGSYIKLFLFNPWVVCFSLIVGGAVLLWVDQLDLKPRHHDATTFPVLMYFYIGCAQCVAM
IPGVSRSGASIVAAMLFGADKRAAAEFSFFLAIPTMVGAFVYDLYKSRADLTTDHMTIVAVGFVVSFITAIIVVKTFLGY
VTRHGFQLFAWWRVVVGTLGLIALAMGR

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=265, Percent_Identity=43.3962264150943, Blast_Score=190, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_RHOP2 (Q2J2D8)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_484283.1
- STRING:   Q2J2D8
- GeneID:   3908588
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_0661
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   IERTRIS
- ProtClustDB:   PRK00281
- BioCyc:   RPAL316058:RPB_0661-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29156; Mature: 29156

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1a1a8cf4)-; HASH(0x1ad8eff4)-; HASH(0x1ad8eebc)-; HASH(0x1adfc828)-; HASH(0x1adfc84c)-; HASH(0x1adfc81c)-; HASH(0x1a591524)-; HASH(0x1adff86c)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure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HHHCCHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA