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The map label for this gene is aroB [H]

Identifier: 86747662

GI number: 86747662

Start: 601413

End: 602561

Strand: Direct

Name: aroB [H]

Synonym: RPB_0536

Alternate gene names: 86747662

Gene position: 601413-602561 (Clockwise)

Preceding gene: 86747661

Following gene: 86747663

Centisome position: 11.28

GC content: 70.23

Gene sequence:

>1149_bases
ATGACTGCGCCGCTGAACCATTCCGCTCCGATCAAGGTCGAGGTCGCGCTCGGCGATCGCGCCTACGACATCGTGATCGG
CCGCAACGTGCTCGGCACGCTCGGCGAGCGGATCGCCAAGCTGCGGCCCGGCGCGCGCACCGCGATCGTCACCGATCGCA
CCGTGGCGCGGACCTGGCTGGCGCCGACCGAGGCGGCGCTGGATGCCGCCGGCATCGCGCATGCGCGCGTCGTGGTCGGC
GAGGGCGAAAGCTCCAAGACCTATGCGGGGCTGGCGGAAGTCAGCGAGGCGCTGATCGCCGCCAAGATCGAACGCAACGA
TCTGGTGATCGCGCTCGGCGGCGGCGTGGTCGGCGATCTCGCCGGCTTCGCGGCGTCGATCCTGCGCCGCGGCGTCGATT
TCGTGCAGGTGCCGACCTCGCTGCTGGCACAGGTTGATTCGTCGGTCGGCGGCAAGACCGGCATCAACTCGCCGCAGGGC
AAGAACCTGCTCGGCGCGTTCCATCAGCCCGTATTGGTGATCGCCGACACCGCGGTGCTCGACACGCTGTCGCCGCGCCA
GTTCCGTGCCGGCTATGCCGAAGTGGCGAAATACGGCGCGCTCGGCGACGAGGCGTTCTTCGCCTGGCTCGAAGCCAATC
ACGCCGAGATCGTCTCAGGCGGGCCGGCGCGCGAGCACGCCATCGCCACGTCGTGCCGGGCGAAGGCGGCGATCGTGGCG
CGCGACGAGCGCGAAAACGGCGAGCGCGCGCTGCTCAATCTCGGCCACACGTTCGGCCATGCGCTGGAGGCCGCGACCGG
CTTCTCCGACCGGCTGTTTCACGGCGAGGGCGTGGCGATCGGCATGGTGCTGGCGGCGCGGTTCTCCGCCGAGCGCGGCA
TGATGCCGGAGGCCGACGCCATCCGGCTGCAGCGCCATCTCGCCGATGTCGGCCTGCCGACCCGGCTGCAGGACATCGCC
GGCTTCGCCCAGGAAGGCCTCGCCGACGCCGACGCGCTGTTGGCGCTGATGACTCAGGACAAGAAGGTCAAACGCGGCCA
GCTCACCTTCATCCTGATGGAAGGGATCGGCCGCGCGGTGATCGCCGACAAGGTCGAGCCGGCGCCGGTTCGCGATTTCC
TGGCCCGGCAGCTCGCGCGCGCATCGTGA

Upstream 100 bases:

>100_bases
CATCGCGCGATGTGCCGCACGAGAAAATCGTCGACGAATGCGTTGCCGCGCTGCACGACTATCTCTGCAGCGCACCCGCC
CCAACCCTGAGCGAGACACC

Downstream 100 bases:

>100_bases
GCGAGCGCGAGATCATGGACTGGGTGACGTCCGGTATCGTCATCGCCTGTCTGTTCGGCTCGGCGTTCTTCTCCGCCAGC
GAGACCGCACTGACCGCGGC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MTAPLNHSAPIKVEVALGDRAYDIVIGRNVLGTLGERIAKLRPGARTAIVTDRTVARTWLAPTEAALDAAGIAHARVVVG
EGESSKTYAGLAEVSEALIAAKIERNDLVIALGGGVVGDLAGFAASILRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQG
KNLLGAFHQPVLVIADTAVLDTLSPRQFRAGYAEVAKYGALGDEAFFAWLEANHAEIVSGGPAREHAIATSCRAKAAIVA
RDERENGERALLNLGHTFGHALEAATGFSDRLFHGEGVAIGMVLAARFSAERGMMPEADAIRLQRHLADVGLPTRLQDIA
GFAQEGLADADALLALMTQDKKVKRGQLTFILMEGIGRAVIADKVEPAPVRDFLARQLARAS

Sequences:

>Translated_382_residues
MTAPLNHSAPIKVEVALGDRAYDIVIGRNVLGTLGERIAKLRPGARTAIVTDRTVARTWLAPTEAALDAAGIAHARVVVG
EGESSKTYAGLAEVSEALIAAKIERNDLVIALGGGVVGDLAGFAASILRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQG
KNLLGAFHQPVLVIADTAVLDTLSPRQFRAGYAEVAKYGALGDEAFFAWLEANHAEIVSGGPAREHAIATSCRAKAAIVA
RDERENGERALLNLGHTFGHALEAATGFSDRLFHGEGVAIGMVLAARFSAERGMMPEADAIRLQRHLADVGLPTRLQDIA
GFAQEGLADADALLALMTQDKKVKRGQLTFILMEGIGRAVIADKVEPAPVRDFLARQLARAS
>Mature_381_residues
TAPLNHSAPIKVEVALGDRAYDIVIGRNVLGTLGERIAKLRPGARTAIVTDRTVARTWLAPTEAALDAAGIAHARVVVGE
GESSKTYAGLAEVSEALIAAKIERNDLVIALGGGVVGDLAGFAASILRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQGK
NLLGAFHQPVLVIADTAVLDTLSPRQFRAGYAEVAKYGALGDEAFFAWLEANHAEIVSGGPAREHAIATSCRAKAAIVAR
DERENGERALLNLGHTFGHALEAATGFSDRLFHGEGVAIGMVLAARFSAERGMMPEADAIRLQRHLADVGLPTRLQDIAG
FAQEGLADADALLALMTQDKKVKRGQLTFILMEGIGRAVIADKVEPAPVRDFLARQLARAS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=349, Percent_Identity=45.2722063037249, Blast_Score=254, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6320332, Length=372, Percent_Identity=35.2150537634409, Blast_Score=185, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40138; Mature: 40007

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPLNHSAPIKVEVALGDRAYDIVIGRNVLGTLGERIAKLRPGARTAIVTDRTVARTWL
CCCCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHC
APTEAALDAAGIAHARVVVGEGESSKTYAGLAEVSEALIAAKIERNDLVIALGGGVVGDL
CCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEECCCCEEEEECCCHHHHH
AGFAASILRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQGKNLLGAFHQPVLVIADTAVL
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEECHHHH
DTLSPRQFRAGYAEVAKYGALGDEAFFAWLEANHAEIVSGGPAREHAIATSCRAKAAIVA
HCCCCHHHHCCHHHHHHHCCCCHHHHHEEHCCCCCEEECCCCCHHHHHHHHHHHCEEEEE
RDERENGERALLNLGHTFGHALEAATGFSDRLFHGEGVAIGMVLAARFSAERGMMPEADA
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEECCCCHHHHHHHHHHHHHHCCCCCCHHH
IRLQRHLADVGLPTRLQDIAGFAQEGLADADALLALMTQDKKVKRGQLTFILMEGIGRAV
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCEE
IADKVEPAPVRDFLARQLARAS
HHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TAPLNHSAPIKVEVALGDRAYDIVIGRNVLGTLGERIAKLRPGARTAIVTDRTVARTWL
CCCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHC
APTEAALDAAGIAHARVVVGEGESSKTYAGLAEVSEALIAAKIERNDLVIALGGGVVGDL
CCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEECCCCEEEEECCCHHHHH
AGFAASILRRGVDFVQVPTSLLAQVDSSVGGKTGINSPQGKNLLGAFHQPVLVIADTAVL
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEECHHHH
DTLSPRQFRAGYAEVAKYGALGDEAFFAWLEANHAEIVSGGPAREHAIATSCRAKAAIVA
HCCCCHHHHCCHHHHHHHCCCCHHHHHEEHCCCCCEEECCCCCHHHHHHHHHHHCEEEEE
RDERENGERALLNLGHTFGHALEAATGFSDRLFHGEGVAIGMVLAARFSAERGMMPEADA
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEECCCCHHHHHHHHHHHHHHCCCCCCHHH
IRLQRHLADVGLPTRLQDIAGFAQEGLADADALLALMTQDKKVKRGQLTFILMEGIGRAV
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCEE
IADKVEPAPVRDFLARQLARAS
HHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA