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The map label for this gene is aroK [H]

Identifier: 86747661

GI number: 86747661

Start: 600799

End: 601416

Strand: Direct

Name: aroK [H]

Synonym: RPB_0535

Alternate gene names: 86747661

Gene position: 600799-601416 (Clockwise)

Preceding gene: 86747656

Following gene: 86747662

Centisome position: 11.27

GC content: 70.06

Gene sequence:

>618_bases
ATGTCTGACAGCGCACCGTCGGCCGCCGCCGCCAGGTCCCAGCAGGAAGCCGAGATCGTCGCGGCGCTGGGCGAGCGCCC
GGTCGTGCTTATCGGCATGATGGGCGCCGGCAAGTCGACCGTCGGCCGCCGGCTGGCGCTGCGGCTCGGGCTGCCGTTTC
TGGACGCCGACACCGAGATCGAACAGGCCGCGGCGATGACGATCCCGGAGATTTTCGAAACCCACGGCGAGCCGCATTTC
CGCGACGGCGAGGCCCGGGTGATCGCCCGGCTGCTCGATGGCGGCGCCAAGATTCTCGCGACCGGCGGCGGCGCGTTCAT
GCGCGAGGAGACCCGCGCGCGGATTCGCGACAAGGCGATCTCGATGTGGCTCGAGGCCGAGGCCGACGTCATCCTGCGCC
GGGTCAAGCGCCGCGCCGACCGGCCGCTGCTGCAGACCGCGGATCCGGCCGGAACCATCGCCCGGCTGATCGGCGAGCGC
TATCCGGTGTATCGTGGCGCCGACCTGACGATCGCATCGCGCGATGTGCCGCACGAGAAAATCGTCGACGAATGCGTTGC
CGCGCTGCACGACTATCTCTGCAGCGCACCCGCCCCAACCCTGAGCGAGACACCATGA

Upstream 100 bases:

>100_bases
CGCGTGGCAAGAGACTCTGGCAACCGCAGCAAGCGCAGTAGTATAGCTGGCCGTTCCGAGCCCAAGCGATCCCGCGCCCA
AGCCCACGGGTGATACGACT

Downstream 100 bases:

>100_bases
CTGCGCCGCTGAACCATTCCGCTCCGATCAAGGTCGAGGTCGCGCTCGGCGATCGCGCCTACGACATCGTGATCGGCCGC
AACGTGCTCGGCACGCTCGG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSDSAPSAAAARSQQEAEIVAALGERPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEIEQAAAMTIPEIFETHGEPHF
RDGEARVIARLLDGGAKILATGGGAFMREETRARIRDKAISMWLEAEADVILRRVKRRADRPLLQTADPAGTIARLIGER
YPVYRGADLTIASRDVPHEKIVDECVAALHDYLCSAPAPTLSETP

Sequences:

>Translated_205_residues
MSDSAPSAAAARSQQEAEIVAALGERPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEIEQAAAMTIPEIFETHGEPHF
RDGEARVIARLLDGGAKILATGGGAFMREETRARIRDKAISMWLEAEADVILRRVKRRADRPLLQTADPAGTIARLIGER
YPVYRGADLTIASRDVPHEKIVDECVAALHDYLCSAPAPTLSETP
>Mature_204_residues
SDSAPSAAAARSQQEAEIVAALGERPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEIEQAAAMTIPEIFETHGEPHFR
DGEARVIARLLDGGAKILATGGGAFMREETRARIRDKAISMWLEAEADVILRRVKRRADRPLLQTADPAGTIARLIGERY
PVYRGADLTIASRDVPHEKIVDECVAALHDYLCSAPAPTLSETP

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=168, Percent_Identity=36.9047619047619, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786587, Length=162, Percent_Identity=30.8641975308642, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 22094; Mature: 21962

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSAPSAAAARSQQEAEIVAALGERPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEI
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHH
EQAAAMTIPEIFETHGEPHFRDGEARVIARLLDGGAKILATGGGAFMREETRARIRDKAI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
SMWLEAEADVILRRVKRRADRPLLQTADPAGTIARLIGERYPVYRGADLTIASRDVPHEK
HHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCHHH
IVDECVAALHDYLCSAPAPTLSETP
HHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SDSAPSAAAARSQQEAEIVAALGERPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEI
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHH
EQAAAMTIPEIFETHGEPHFRDGEARVIARLLDGGAKILATGGGAFMREETRARIRDKAI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
SMWLEAEADVILRRVKRRADRPLLQTADPAGTIARLIGERYPVYRGADLTIASRDVPHEK
HHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCHHH
IVDECVAALHDYLCSAPAPTLSETP
HHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA