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The map label for this gene is accA

Identifier: 86747658

GI number: 86747658

Start: 598297

End: 599259

Strand: Reverse

Name: accA

Synonym: RPB_0532

Alternate gene names: 86747658

Gene position: 599259-598297 (Counterclockwise)

Preceding gene: 86747659

Following gene: 86747657

Centisome position: 11.24

GC content: 67.5

Gene sequence:

>963_bases
ATGTCCGAGCCCATGCGCAGCTATCTCGACTTCGAAAAGCCGGTCGCGGAACTCGATTCCAAGATCGACGAATTGCGCGC
GCTGGCCGCCTCCGGCAGCGACATCCACGAGGAAGTCGCCAAGATCGAGGAGAAGGCCGTCCAGGCCCTGAACGAGCTCT
ATGCGACGCTGACGCCGTGGCAGAAGACCCAGGTGGCGCGGCATCCGCAGCGGCCGCATTGCGTCGACTACATCGAAGGA
CTGATCACCGAGTTCACGCCTCTGGCCGGCGACCGCAAGTTCGGCGAGGACGAGGCGCTGATCGGCGGCTTCGGCCGTTT
CCGGGGCGAGAGCATCTGCGTGATCGGCCAGGAGAAAGGCTCCTCGACCGAGACCCGCCTCAAGCACAATTTCGGCATGG
CCCGCCCCGAAGGCTACCGCAAGGCGGTCCGCCTGATGGACATGGCCGACCGCTTCGGCATCCCGGTGCTGTCGCTGGTC
GACACCGCCGGCGCCTATCCGGGCATCGGCGCGGAAGAGCGCGGCCAGGCCGAGGCGATCGCGCGCTCGACCGACGCCTG
CTTGTCGCTCGGCGTTCCGAATGTCGCCGTCGTGATCGGCGAGGGCGGCTCCGGCGGCGCGATCGCGATCGCCACCGCCA
ACAAGGTCTTGATGCTCGAACACGCGATCTACAGCGTGATCTCGCCCGAAGCGGCCTCCTCGATCCTGTGGCGCGACGGC
ACCAAGGCCCAGGAAGCCGCTAATTCGATGAAGATCACCGCCCAGGATCTGCTGCGATTCGGCGTGATCGACCAGATCCT
GCCCGAGCCCAAGGGCGGCGCCCACCGCGACCCGGCCGCCATGATCGCAACCACCGGGGACGCCATCGCGGCGGCCTTCG
CCGAACTCGCCGGGCTCGATGCCGGCACGGTTCGCGCCCGGCGACGGCAGAAATTCCTCGAAATCGGCCGCAAGCTGGGC
TGA

Upstream 100 bases:

>100_bases
TAAGCCGCCGGCCGGCCCAGCCGCTTGACTTGATGCGCGTTCGGCTCGAAAAGCCGGAGCCGGGCCGATATCGGTCGCAC
AACCTCCCCATGTCCTGGTC

Downstream 100 bases:

>100_bases
CGACCCGGGCAGCGCCGGCATTGCCGGTTTGCTAACCATCCGCTCCGACAGCGACGGATTCCGTCCGCCCGGCCGCAGTT
TTGCCGCGGGGGCCACGTTC

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSEPMRSYLDFEKPVAELDSKIDELRALAASGSDIHEEVAKIEEKAVQALNELYATLTPWQKTQVARHPQRPHCVDYIEG
LITEFTPLAGDRKFGEDEALIGGFGRFRGESICVIGQEKGSSTETRLKHNFGMARPEGYRKAVRLMDMADRFGIPVLSLV
DTAGAYPGIGAEERGQAEAIARSTDACLSLGVPNVAVVIGEGGSGGAIAIATANKVLMLEHAIYSVISPEAASSILWRDG
TKAQEAANSMKITAQDLLRFGVIDQILPEPKGGAHRDPAAMIATTGDAIAAAFAELAGLDAGTVRARRRQKFLEIGRKLG

Sequences:

>Translated_320_residues
MSEPMRSYLDFEKPVAELDSKIDELRALAASGSDIHEEVAKIEEKAVQALNELYATLTPWQKTQVARHPQRPHCVDYIEG
LITEFTPLAGDRKFGEDEALIGGFGRFRGESICVIGQEKGSSTETRLKHNFGMARPEGYRKAVRLMDMADRFGIPVLSLV
DTAGAYPGIGAEERGQAEAIARSTDACLSLGVPNVAVVIGEGGSGGAIAIATANKVLMLEHAIYSVISPEAASSILWRDG
TKAQEAANSMKITAQDLLRFGVIDQILPEPKGGAHRDPAAMIATTGDAIAAAFAELAGLDAGTVRARRRQKFLEIGRKLG
>Mature_319_residues
SEPMRSYLDFEKPVAELDSKIDELRALAASGSDIHEEVAKIEEKAVQALNELYATLTPWQKTQVARHPQRPHCVDYIEGL
ITEFTPLAGDRKFGEDEALIGGFGRFRGESICVIGQEKGSSTETRLKHNFGMARPEGYRKAVRLMDMADRFGIPVLSLVD
TAGAYPGIGAEERGQAEAIARSTDACLSLGVPNVAVVIGEGGSGGAIAIATANKVLMLEHAIYSVISPEAASSILWRDGT
KAQEAANSMKITAQDLLRFGVIDQILPEPKGGAHRDPAAMIATTGDAIAAAFAELAGLDAGTVRARRRQKFLEIGRKLG

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=314, Percent_Identity=48.7261146496815, Blast_Score=316, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_RHOP2 (Q2J2R7)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_484154.1
- ProteinModelPortal:   Q2J2R7
- SMR:   Q2J2R7
- STRING:   Q2J2R7
- GeneID:   3909571
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_0532
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   RPAL316058:RPB_0532-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 34287; Mature: 34156

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPMRSYLDFEKPVAELDSKIDELRALAASGSDIHEEVAKIEEKAVQALNELYATLTPW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
QKTQVARHPQRPHCVDYIEGLITEFTPLAGDRKFGEDEALIGGFGRFRGESICVIGQEKG
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHCCCCEEEEEECCCC
SSTETRLKHNFGMARPEGYRKAVRLMDMADRFGIPVLSLVDTAGAYPGIGAEERGQAEAI
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHH
ARSTDACLSLGVPNVAVVIGEGGSGGAIAIATANKVLMLEHAIYSVISPEAASSILWRDG
HHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHCCC
TKAQEAANSMKITAQDLLRFGVIDQILPEPKGGAHRDPAAMIATTGDAIAAAFAELAGLD
CHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCC
AGTVRARRRQKFLEIGRKLG
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEPMRSYLDFEKPVAELDSKIDELRALAASGSDIHEEVAKIEEKAVQALNELYATLTPW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
QKTQVARHPQRPHCVDYIEGLITEFTPLAGDRKFGEDEALIGGFGRFRGESICVIGQEKG
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHCCCCEEEEEECCCC
SSTETRLKHNFGMARPEGYRKAVRLMDMADRFGIPVLSLVDTAGAYPGIGAEERGQAEAI
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHH
ARSTDACLSLGVPNVAVVIGEGGSGGAIAIATANKVLMLEHAIYSVISPEAASSILWRDG
HHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHCCC
TKAQEAANSMKITAQDLLRFGVIDQILPEPKGGAHRDPAAMIATTGDAIAAAFAELAGLD
CHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCC
AGTVRARRRQKFLEIGRKLG
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA