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The map label for this gene is xerD [H]

Identifier: 86747659

GI number: 86747659

Start: 599413

End: 600456

Strand: Reverse

Name: xerD [H]

Synonym: RPB_0533

Alternate gene names: 86747659

Gene position: 600456-599413 (Counterclockwise)

Preceding gene: 86747660

Following gene: 86747658

Centisome position: 11.26

GC content: 70.69

Gene sequence:

>1044_bases
ATGCGAAAACCGCGAGCAAGATTCAGTCCTTCAGCCAGCGTCCCGGCCACCGCTGCCGGCGAGCGGGAGGCCGCGCCGCT
GCGGCCCACCTCATATTCCGATGCCGGACTGAGCGAGCTGTTCCTCGACATGATCGCGGCCGAACAGGGCGCCTCCGCCA
ACACGCTCGACGCCTACCGCCGCGACCTCGCCGACCTGTCGCACTACCTCGGCCGCCGCCGCAAGAGCATCGCCTCCGCC
GACACCGAGGCGCTGCGCGGCTATCTCGCCGATCTGGATACCCGCGGCTTCGCATCGACGAGCGTCGCGCGGCGGCTGTC
GGCGCTGCGGCATCTGTTTCGATTCCTGCTGAGCGAGCGGATCCGGGTCGATGATCCGGCGGCGATCCTGTCCGGACCGA
AGCGCGGCCGCGGGCTGCCCAAGGTGCTTTCGATCGCCGATGTCGACCGCCTGCTCGGCTGCGCGCGCCAGGAGGCCGAC
GCCGCCGAGGGCGCGGCGGGGCTGCGCGCGGCGCGGCTGTATTGCCTGCTGGAGGTGTTGTACGCGACCGGGCTGCGCGT
CTCCGAACTGGTGGCGCTGCCGCGGACGGCGGCGCGGGGCGATGCCCGGATGATCGTGGTCCGCGGCAAGGGCGACAAGG
AGCGGCTGGTGCCGCTCAATGGCAGTTCCAAAGCCGCGATGACGCGCTATCTCGCGACCGCCGCGGCGGCCGAAAAGGCC
GCGGCCGGCGGCAAGAAGACCGCCGCGCCCGCGTCCAAATGGCTGTTTCCGTCGTTCGGCGAGAGCGGCCATCTGACCCG
GCAGCATTTCGCCCGCGACCTCAAGGAGCTCGCCGCGCGCGCCGGGCTGCCGCCGCGGCTGGTCAGCCCGCATGTGCTGC
GCCACGCCTTCGCCAGCCATCTGCTGCACAACGGCGCCGATCTGCGGATCGTCCAGACCCTGCTCGGTCACAGCGACATC
TCGACCACGCAGATCTATACCCATGTGGTCGAAGACCGGCTGAAGAGCCTGGTCCGCGACCTGCATCCGCTGGCGGAAGG
CTGA

Upstream 100 bases:

>100_bases
TCTTCGCGCTGGCCAATTTTACCGCCCCGAAATCGCGGGACATCACCGTGGTGGTGCCGCAAGACAAATTTCTCAAGAAA
TAGCAGTTAGGCTCGGCGGC

Downstream 100 bases:

>100_bases
GGCCGGCGCGCCGCGTCAGCCTTGCAACTCCAACGGCGCCTGATTCTTTTGCCTAAGCCGCCGGCCGGCCCAGCCGCTTG
ACTTGATGCGCGTTCGGCTC

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MRKPRARFSPSASVPATAAGEREAAPLRPTSYSDAGLSELFLDMIAAEQGASANTLDAYRRDLADLSHYLGRRRKSIASA
DTEALRGYLADLDTRGFASTSVARRLSALRHLFRFLLSERIRVDDPAAILSGPKRGRGLPKVLSIADVDRLLGCARQEAD
AAEGAAGLRAARLYCLLEVLYATGLRVSELVALPRTAARGDARMIVVRGKGDKERLVPLNGSSKAAMTRYLATAAAAEKA
AAGGKKTAAPASKWLFPSFGESGHLTRQHFARDLKELAARAGLPPRLVSPHVLRHAFASHLLHNGADLRIVQTLLGHSDI
STTQIYTHVVEDRLKSLVRDLHPLAEG

Sequences:

>Translated_347_residues
MRKPRARFSPSASVPATAAGEREAAPLRPTSYSDAGLSELFLDMIAAEQGASANTLDAYRRDLADLSHYLGRRRKSIASA
DTEALRGYLADLDTRGFASTSVARRLSALRHLFRFLLSERIRVDDPAAILSGPKRGRGLPKVLSIADVDRLLGCARQEAD
AAEGAAGLRAARLYCLLEVLYATGLRVSELVALPRTAARGDARMIVVRGKGDKERLVPLNGSSKAAMTRYLATAAAAEKA
AAGGKKTAAPASKWLFPSFGESGHLTRQHFARDLKELAARAGLPPRLVSPHVLRHAFASHLLHNGADLRIVQTLLGHSDI
STTQIYTHVVEDRLKSLVRDLHPLAEG
>Mature_347_residues
MRKPRARFSPSASVPATAAGEREAAPLRPTSYSDAGLSELFLDMIAAEQGASANTLDAYRRDLADLSHYLGRRRKSIASA
DTEALRGYLADLDTRGFASTSVARRLSALRHLFRFLLSERIRVDDPAAILSGPKRGRGLPKVLSIADVDRLLGCARQEAD
AAEGAAGLRAARLYCLLEVLYATGLRVSELVALPRTAARGDARMIVVRGKGDKERLVPLNGSSKAAMTRYLATAAAAEKA
AAGGKKTAAPASKWLFPSFGESGHLTRQHFARDLKELAARAGLPPRLVSPHVLRHAFASHLLHNGADLRIVQTLLGHSDI
STTQIYTHVVEDRLKSLVRDLHPLAEG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=305, Percent_Identity=44.9180327868852, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1790244, Length=312, Percent_Identity=33.0128205128205, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1790768, Length=165, Percent_Identity=32.1212121212121, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37389; Mature: 37389

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKPRARFSPSASVPATAAGEREAAPLRPTSYSDAGLSELFLDMIAAEQGASANTLDAYR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
RDLADLSHYLGRRRKSIASADTEALRGYLADLDTRGFASTSVARRLSALRHLFRFLLSER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
IRVDDPAAILSGPKRGRGLPKVLSIADVDRLLGCARQEADAAEGAAGLRAARLYCLLEVL
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YATGLRVSELVALPRTAARGDARMIVVRGKGDKERLVPLNGSSKAAMTRYLATAAAAEKA
HHCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHH
AAGGKKTAAPASKWLFPSFGESGHLTRQHFARDLKELAARAGLPPRLVSPHVLRHAFASH
HCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LLHNGADLRIVQTLLGHSDISTTQIYTHVVEDRLKSLVRDLHPLAEG
HHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKPRARFSPSASVPATAAGEREAAPLRPTSYSDAGLSELFLDMIAAEQGASANTLDAYR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
RDLADLSHYLGRRRKSIASADTEALRGYLADLDTRGFASTSVARRLSALRHLFRFLLSER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
IRVDDPAAILSGPKRGRGLPKVLSIADVDRLLGCARQEADAAEGAAGLRAARLYCLLEVL
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YATGLRVSELVALPRTAARGDARMIVVRGKGDKERLVPLNGSSKAAMTRYLATAAAAEKA
HHCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHH
AAGGKKTAAPASKWLFPSFGESGHLTRQHFARDLKELAARAGLPPRLVSPHVLRHAFASH
HCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LLHNGADLRIVQTLLGHSDISTTQIYTHVVEDRLKSLVRDLHPLAEG
HHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]