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The map label for this gene is ywlC [H]

Identifier: 86608509

GI number: 86608509

Start: 1073024

End: 1074115

Strand: Direct

Name: ywlC [H]

Synonym: CYB_1030

Alternate gene names: 86608509

Gene position: 1073024-1074115 (Clockwise)

Preceding gene: 86608508

Following gene: 86608510

Centisome position: 35.22

GC content: 64.56

Gene sequence:

>1092_bases
ATGCAGACGGAAATTCTCTCACCCACTCCTGAGCACATTGCCGTAGCGGCGGCAGCCTTGCTGCGGGGCCAGTTGGTGGC
CATCCCCACGGAGACGGTTTACGGCCTGGCGGGCAATGGCTTGGATGAGCAGGCAGTGGCAAACATTTTTGCCGCCAAGG
AGCGCCCCCGCTTCGATCCCCTGATCCTGCATCTGCCGGCTGGGGTGACCCTAGAGCAATTGCAGGGGTGGCTGGTGGAC
GTGTCGGCTTTTACTCCCGCCGCTCGCGCTCTGCTGGGATCCCTGATCGACACCTTCTGGCCGGGGCCCCTAACCTTGGT
GCTGCCCAAGTGCCCCACCGTGCCGGATCTGGTAAGCAGCGGGTTGCCTACTGTTGCCCTGCGGGTGCCTGCTCACCCGG
TGGCTCAAGCTTTGTTGCAGGCGGTGCAAACCCCTCTGGCTGCCCCCAGTGCCAATCGCTTTGGCCGCATCAGCCCCACC
TCAGCCCAGGCCGTCTATGCAGAGTTGGGAGGGCGGATCCCTTACATCTTGGATGGGGGAGAGTGTGCTGTGGGCCTGGA
GTCCACCGTGCTAAAGCTCAGCCCCGAGGGGATCCCAACGCTGCTGCGCCCAGGAGGGATCCCACTGGAAGCCCTGGAGG
CCCACCTGGGGTTGCCCATCCGGTTGCCCCCAGAACAGGCCCCCAAGGATGGCACAACGGGCCCGCCAGAAGCGCCGGGA
CGACTGAGCAGCCACTATGCCCCCAGTAAGCCCCTCCGGCTTTTGCCCACCCCTTTTGCCCAGCTTCAGCCCGGCGATTG
GCAACAGGTGCAGCACCTGACAACCGGTCATTCCCACCTGGGCATCCTCAGCTTTGCCACGGATCCGCAGGCTCTGCTGA
ACACCCTCTCCCGCCATTGGCCGGGGATCACTTTCAGTTTGGAGTGTTTGGGTTCGGATCCCAAGGCAGCCGCCCGCGCC
CTCTTTGCCAGCCTGCGCCGACTGGATGAGGGAGATGCTACGCTCCTGCTGGCAGAGCCCCCACCCATCTCGACGGGGTT
GGGCTATGCGATGATGGATCGGCTACGCCGGGCCAGCAGCCTTTCGCGTTAG

Upstream 100 bases:

>100_bases
GCGCTGCTGTTTGGGGATCAAATCAACATCGCCCTCTACCAGGCGCAAAAATGGATTGAAGAACGGGATCCCTAGCCCTT
ACTCCAAATCCGAGTCATGG

Downstream 100 bases:

>100_bases
CGTCGCTTAGCGATATGGAACTCTCCCCCCTCGTTGCCATCGTAATGGGTAGCGATTCCGATTTGCCCACCCTTGCACCT
GCCGCCCAGGTGTGTGAGGA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MQTEILSPTPEHIAVAAAALLRGQLVAIPTETVYGLAGNGLDEQAVANIFAAKERPRFDPLILHLPAGVTLEQLQGWLVD
VSAFTPAARALLGSLIDTFWPGPLTLVLPKCPTVPDLVSSGLPTVALRVPAHPVAQALLQAVQTPLAAPSANRFGRISPT
SAQAVYAELGGRIPYILDGGECAVGLESTVLKLSPEGIPTLLRPGGIPLEALEAHLGLPIRLPPEQAPKDGTTGPPEAPG
RLSSHYAPSKPLRLLPTPFAQLQPGDWQQVQHLTTGHSHLGILSFATDPQALLNTLSRHWPGITFSLECLGSDPKAAARA
LFASLRRLDEGDATLLLAEPPPISTGLGYAMMDRLRRASSLSR

Sequences:

>Translated_363_residues
MQTEILSPTPEHIAVAAAALLRGQLVAIPTETVYGLAGNGLDEQAVANIFAAKERPRFDPLILHLPAGVTLEQLQGWLVD
VSAFTPAARALLGSLIDTFWPGPLTLVLPKCPTVPDLVSSGLPTVALRVPAHPVAQALLQAVQTPLAAPSANRFGRISPT
SAQAVYAELGGRIPYILDGGECAVGLESTVLKLSPEGIPTLLRPGGIPLEALEAHLGLPIRLPPEQAPKDGTTGPPEAPG
RLSSHYAPSKPLRLLPTPFAQLQPGDWQQVQHLTTGHSHLGILSFATDPQALLNTLSRHWPGITFSLECLGSDPKAAARA
LFASLRRLDEGDATLLLAEPPPISTGLGYAMMDRLRRASSLSR
>Mature_363_residues
MQTEILSPTPEHIAVAAAALLRGQLVAIPTETVYGLAGNGLDEQAVANIFAAKERPRFDPLILHLPAGVTLEQLQGWLVD
VSAFTPAARALLGSLIDTFWPGPLTLVLPKCPTVPDLVSSGLPTVALRVPAHPVAQALLQAVQTPLAAPSANRFGRISPT
SAQAVYAELGGRIPYILDGGECAVGLESTVLKLSPEGIPTLLRPGGIPLEALEAHLGLPIRLPPEQAPKDGTTGPPEAPG
RLSSHYAPSKPLRLLPTPFAQLQPGDWQQVQHLTTGHSHLGILSFATDPQALLNTLSRHWPGITFSLECLGSDPKAAARA
LFASLRRLDEGDATLLLAEPPPISTGLGYAMMDRLRRASSLSR

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=225, Percent_Identity=31.5555555555556, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI2367210, Length=166, Percent_Identity=32.5301204819277, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17537239, Length=219, Percent_Identity=29.6803652968037, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321269, Length=386, Percent_Identity=34.4559585492228, Blast_Score=176, Evalue=4e-45,
Organism=Drosophila melanogaster, GI78707274, Length=200, Percent_Identity=28, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 38298; Mature: 38298

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTEILSPTPEHIAVAAAALLRGQLVAIPTETVYGLAGNGLDEQAVANIFAAKERPRFDP
CCCCCCCCCHHHHHHHHHHHHCCCEEEECCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCC
LILHLPAGVTLEQLQGWLVDVSAFTPAARALLGSLIDTFWPGPLTLVLPKCPTVPDLVSS
EEEECCCCCCHHHHCCCEEEHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHC
GLPTVALRVPAHPVAQALLQAVQTPLAAPSANRFGRISPTSAQAVYAELGGRIPYILDGG
CCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECC
ECAVGLESTVLKLSPEGIPTLLRPGGIPLEALEAHLGLPIRLPPEQAPKDGTTGPPEAPG
CEEECCCCEEEEECCCCCCHHCCCCCCCHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCC
RLSSHYAPSKPLRLLPTPFAQLQPGDWQQVQHLTTGHSHLGILSFATDPQALLNTLSRHW
CCCCCCCCCCCCEECCCCHHHCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHC
PGITFSLECLGSDPKAAARALFASLRRLDEGDATLLLAEPPPISTGLGYAMMDRLRRASS
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
LSR
CCC
>Mature Secondary Structure
MQTEILSPTPEHIAVAAAALLRGQLVAIPTETVYGLAGNGLDEQAVANIFAAKERPRFDP
CCCCCCCCCHHHHHHHHHHHHCCCEEEECCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCC
LILHLPAGVTLEQLQGWLVDVSAFTPAARALLGSLIDTFWPGPLTLVLPKCPTVPDLVSS
EEEECCCCCCHHHHCCCEEEHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHC
GLPTVALRVPAHPVAQALLQAVQTPLAAPSANRFGRISPTSAQAVYAELGGRIPYILDGG
CCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECC
ECAVGLESTVLKLSPEGIPTLLRPGGIPLEALEAHLGLPIRLPPEQAPKDGTTGPPEAPG
CEEECCCCEEEEECCCCCCHHCCCCCCCHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCC
RLSSHYAPSKPLRLLPTPFAQLQPGDWQQVQHLTTGHSHLGILSFATDPQALLNTLSRHW
CCCCCCCCCCCCEECCCCHHHCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHC
PGITFSLECLGSDPKAAARALFASLRRLDEGDATLLLAEPPPISTGLGYAMMDRLRRASS
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
LSR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]