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The map label for this gene is clpX

Identifier: 85859381

GI number: 85859381

Start: 1580646

End: 1581908

Strand: Direct

Name: clpX

Synonym: SYN_02786

Alternate gene names: 85859381

Gene position: 1580646-1581908 (Clockwise)

Preceding gene: 85859380

Following gene: 85859382

Centisome position: 49.72

GC content: 44.89

Gene sequence:

>1263_bases
ATGGGTAGAAAAACAACCGATTATTCCAGGGGACAAGAAATGCTTTTTTGTTCATTCTGCGGAAAAACACAAAATGAAGT
AAAAAAACTTGTAGCTGGTCCCACTGCATATATTTGCGATGAATGCATTGAGCTCTGCCGATGTATTGTAGAAGAGGAAG
GTGGAGGGCCGTGTGGACTGGACCTTCAAAAAAGTATTCCGGAACCCAGAATAATCAAGGAGTTTCTCGATCAGTATGTC
GTCGGACAGGAGAGGCCCAAAAAGGTTCTTTCTGTCGCGGTATACAATCACTACAAGCGGCTTTCCGCGCATGCCGATAG
TGATGGGGTGGAAATGCAGAAGAGCAATGTTTTGCTTATCGGTCCCACTGGATCAGGCAAGACGTTACTTGCTAAGACCC
TGGCAAAGCTGCTGAATGTTCCCTTTACCATAGCAGATGCGACGACACTGACGGAGGCGGGATACGTCGGTGAAGATGTG
GAAAACATTATCCTGAGTCTTTTGCAGAATGCGGATTATGATGTTGATAAGGCATCGAAAGGCATTGTATATATTGACGA
AATTGACAAGATCGCCAAGAAGTCGGGAAATCCTTCCATTACCAGGGATGTTTCAGGAGAAGGTGTACAGCAGGCTCTTT
TGAAAATTATAGAGGGAACGCTGGCAAACATTCCGCCTAAGGGTGGAAGAAAACACCCACAACAGGAATTTATCCAGGTG
GATACAACGGGAATTCTTTTCATTTGTGGCGGTGCTTTTAATGACCTTCCCGACATCATAATGAAAAGAACTGGTGTGAA
CGCAATGGGATTCGGTGCCGATATCAAAGGTAAACAAGATCGAAAAATAGGGGAATTGCTTTCAGAAGTTCAGCCTGAGG
ATTTACTCAAATGTGGACTTATTCCTGAGTTTGTGGGAAGGCTGCCTGTCATAGCCCCTTTGAGTGAACTTGATGAGGAC
GATCTGGTAAAGATCCTGGTGGATCCGAAAGATTCAATTGTCAAACAGTATACAAAGGCGTTCGAGCTTGAAAATGTAAA
GTTGAGATTTACGGACAGCGCGCTCAGAGCGGTGGCTAAACTTGCTGTGGATAGAAAATCAGGGGCAAGAGGTTTGCGCG
CAATACTGGAAAACGCCATGCTGGATATCATGTATGACATTCCATCTCGCCAGGACGTTCGGGAGTGTGTGATAAACGAA
GATGTTGTCTTGAATAGAGCACAGCCTATTCTGCTTTTTGAAAAGCAGTCAGAGACAGCTTAA

Upstream 100 bases:

>100_bases
CGTGATTATTATATGACCAGCCAGCAGGCCAAAGAATACGGAATTATCGATGAAATCATTGTTAAGCGGTCATAATAAAT
TACAAAAAGAGGAAGAATGA

Downstream 100 bases:

>100_bases
AATTTCAGCGTTAAAGGCTGAAAACTAAATCGCAGGAAAACAAATATGTTTGATTTTATAAAAAACAAAGAAAAAAACAG
CAATATAAATTCTCTTCCTC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MGRKTTDYSRGQEMLFCSFCGKTQNEVKKLVAGPTAYICDECIELCRCIVEEEGGGPCGLDLQKSIPEPRIIKEFLDQYV
VGQERPKKVLSVAVYNHYKRLSAHADSDGVEMQKSNVLLIGPTGSGKTLLAKTLAKLLNVPFTIADATTLTEAGYVGEDV
ENIILSLLQNADYDVDKASKGIVYIDEIDKIAKKSGNPSITRDVSGEGVQQALLKIIEGTLANIPPKGGRKHPQQEFIQV
DTTGILFICGGAFNDLPDIIMKRTGVNAMGFGADIKGKQDRKIGELLSEVQPEDLLKCGLIPEFVGRLPVIAPLSELDED
DLVKILVDPKDSIVKQYTKAFELENVKLRFTDSALRAVAKLAVDRKSGARGLRAILENAMLDIMYDIPSRQDVRECVINE
DVVLNRAQPILLFEKQSETA

Sequences:

>Translated_420_residues
MGRKTTDYSRGQEMLFCSFCGKTQNEVKKLVAGPTAYICDECIELCRCIVEEEGGGPCGLDLQKSIPEPRIIKEFLDQYV
VGQERPKKVLSVAVYNHYKRLSAHADSDGVEMQKSNVLLIGPTGSGKTLLAKTLAKLLNVPFTIADATTLTEAGYVGEDV
ENIILSLLQNADYDVDKASKGIVYIDEIDKIAKKSGNPSITRDVSGEGVQQALLKIIEGTLANIPPKGGRKHPQQEFIQV
DTTGILFICGGAFNDLPDIIMKRTGVNAMGFGADIKGKQDRKIGELLSEVQPEDLLKCGLIPEFVGRLPVIAPLSELDED
DLVKILVDPKDSIVKQYTKAFELENVKLRFTDSALRAVAKLAVDRKSGARGLRAILENAMLDIMYDIPSRQDVRECVINE
DVVLNRAQPILLFEKQSETA
>Mature_419_residues
GRKTTDYSRGQEMLFCSFCGKTQNEVKKLVAGPTAYICDECIELCRCIVEEEGGGPCGLDLQKSIPEPRIIKEFLDQYVV
GQERPKKVLSVAVYNHYKRLSAHADSDGVEMQKSNVLLIGPTGSGKTLLAKTLAKLLNVPFTIADATTLTEAGYVGEDVE
NIILSLLQNADYDVDKASKGIVYIDEIDKIAKKSGNPSITRDVSGEGVQQALLKIIEGTLANIPPKGGRKHPQQEFIQVD
TTGILFICGGAFNDLPDIIMKRTGVNAMGFGADIKGKQDRKIGELLSEVQPEDLLKCGLIPEFVGRLPVIAPLSELDEDD
LVKILVDPKDSIVKQYTKAFELENVKLRFTDSALRAVAKLAVDRKSGARGLRAILENAMLDIMYDIPSRQDVRECVINED
VVLNRAQPILLFEKQSETA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=328, Percent_Identity=47.2560975609756, Blast_Score=296, Evalue=2e-80,
Organism=Escherichia coli, GI1786642, Length=406, Percent_Identity=63.3004926108374, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=41.747572815534, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982908, Length=308, Percent_Identity=45.4545454545455, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=308, Percent_Identity=45.4545454545455, Blast_Score=268, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=413, Percent_Identity=36.8038740920097, Blast_Score=229, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI71988660, Length=261, Percent_Identity=37.1647509578544, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319704, Length=425, Percent_Identity=39.2941176470588, Blast_Score=258, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=44.6540880503145, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=44.6540880503145, Blast_Score=279, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46085; Mature: 45954

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRKTTDYSRGQEMLFCSFCGKTQNEVKKLVAGPTAYICDECIELCRCIVEEEGGGPCGL
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
DLQKSIPEPRIIKEFLDQYVVGQERPKKVLSVAVYNHYKRLSAHADSDGVEMQKSNVLLI
CHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEE
GPTGSGKTLLAKTLAKLLNVPFTIADATTLTEAGYVGEDVENIILSLLQNADYDVDKASK
ECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
GIVYIDEIDKIAKKSGNPSITRDVSGEGVQQALLKIIEGTLANIPPKGGRKHPQQEFIQV
CEEEHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEE
DTTGILFICGGAFNDLPDIIMKRTGVNAMGFGADIKGKQDRKIGELLSEVQPEDLLKCGL
CCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCC
IPEFVGRLPVIAPLSELDEDDLVKILVDPKDSIVKQYTKAFELENVKLRFTDSALRAVAK
CHHHHCCCCCCCCHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHH
LAVDRKSGARGLRAILENAMLDIMYDIPSRQDVRECVINEDVVLNRAQPILLFEKQSETA
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEECCCCCEEEEECCCCCC
>Mature Secondary Structure 
GRKTTDYSRGQEMLFCSFCGKTQNEVKKLVAGPTAYICDECIELCRCIVEEEGGGPCGL
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
DLQKSIPEPRIIKEFLDQYVVGQERPKKVLSVAVYNHYKRLSAHADSDGVEMQKSNVLLI
CHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEE
GPTGSGKTLLAKTLAKLLNVPFTIADATTLTEAGYVGEDVENIILSLLQNADYDVDKASK
ECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
GIVYIDEIDKIAKKSGNPSITRDVSGEGVQQALLKIIEGTLANIPPKGGRKHPQQEFIQV
CEEEHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEE
DTTGILFICGGAFNDLPDIIMKRTGVNAMGFGADIKGKQDRKIGELLSEVQPEDLLKCGL
CCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCC
IPEFVGRLPVIAPLSELDEDDLVKILVDPKDSIVKQYTKAFELENVKLRFTDSALRAVAK
CHHHHCCCCCCCCHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHH
LAVDRKSGARGLRAILENAMLDIMYDIPSRQDVRECVINEDVVLNRAQPILLFEKQSETA
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEECCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA