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The map label for this gene is groES

Identifier: 85859339

GI number: 85859339

Start: 1535649

End: 1535939

Strand: Direct

Name: groES

Synonym: SYN_00062

Alternate gene names: 85859339

Gene position: 1535649-1535939 (Clockwise)

Preceding gene: 85859338

Following gene: 85859340

Centisome position: 48.3

GC content: 46.74

Gene sequence:

>291_bases
ATGAACATCAGGCCATTACAGGACAGAGTGATCGTTAAGAGACTCGAGGAAGAGCAGAAAACCAAGGGAGGCATTATTAT
CCCCGACACGGCAAAAGAGAAGCCTATTGAAGGTGAAGTTGTCGCCGTTGGCAAAGGCAAGGTAACGGAAGACGGCAAAT
TGCTGCCCCTGGATGTGAAAGTGGGTGATCGTGTTCTGTTCAGCAAGTATGGTGGTACGGAAGTTAAATTTGACGGACAG
GAATATCTCATCATGAGAGAGGATGATATTCTGGGGATCGTGGAGAAATAA

Upstream 100 bases:

>100_bases
GAATTTTATGTTTAAGTTACCGCCAAACCCGTTTTGGAGATAAGAAACCACATTCTTTTTATATCTCAAAAAAATCAACA
GGAAAGGAGAAAGTTTCCGC

Downstream 100 bases:

>100_bases
TTACAGAAGATAACAACGAAGGAGGAGCATATACGTATGGGTGCAAAATTACTGCAGTATGATGAAGAAGCGAGAAAATC
CATCCTGAACGGTGTCAACG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MNIRPLQDRVIVKRLEEEQKTKGGIIIPDTAKEKPIEGEVVAVGKGKVTEDGKLLPLDVKVGDRVLFSKYGGTEVKFDGQ
EYLIMREDDILGIVEK

Sequences:

>Translated_96_residues
MNIRPLQDRVIVKRLEEEQKTKGGIIIPDTAKEKPIEGEVVAVGKGKVTEDGKLLPLDVKVGDRVLFSKYGGTEVKFDGQ
EYLIMREDDILGIVEK
>Mature_96_residues
MNIRPLQDRVIVKRLEEEQKTKGGIIIPDTAKEKPIEGEVVAVGKGKVTEDGKLLPLDVKVGDRVLFSKYGGTEVKFDGQ
EYLIMREDDILGIVEK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=88, Percent_Identity=47.7272727272727, Blast_Score=76, Evalue=6e-15,
Organism=Homo sapiens, GI169210012, Length=88, Percent_Identity=43.1818181818182, Blast_Score=69, Evalue=7e-13,
Organism=Homo sapiens, GI310125356, Length=88, Percent_Identity=42.0454545454545, Blast_Score=62, Evalue=7e-11,
Organism=Homo sapiens, GI239752758, Length=88, Percent_Identity=42.0454545454545, Blast_Score=62, Evalue=7e-11,
Organism=Homo sapiens, GI310118571, Length=88, Percent_Identity=42.0454545454545, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=57.2916666666667, Blast_Score=103, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=47.8723404255319, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324594, Length=96, Percent_Identity=38.5416666666667, Blast_Score=68, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356029, Length=96, Percent_Identity=44.7916666666667, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=45.1612903225806, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10724; Mature: 10724

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRPLQDRVIVKRLEEEQKTKGGIIIPDTAKEKPIEGEVVAVGKGKVTEDGKLLPLDVK
CCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEECCCEECCCCCEEEEEEC
VGDRVLFSKYGGTEVKFDGQEYLIMREDDILGIVEK
CCCEEEEECCCCEEEEECCCEEEEEECCCEEEEECC
>Mature Secondary Structure
MNIRPLQDRVIVKRLEEEQKTKGGIIIPDTAKEKPIEGEVVAVGKGKVTEDGKLLPLDVK
CCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEECCCEECCCCCEEEEEEC
VGDRVLFSKYGGTEVKFDGQEYLIMREDDILGIVEK
CCCEEEEECCCCEEEEECCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA