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The map label for this gene is pgsA [H]

Identifier: 85859284

GI number: 85859284

Start: 1469099

End: 1469683

Strand: Direct

Name: pgsA [H]

Synonym: SYN_02166

Alternate gene names: 85859284

Gene position: 1469099-1469683 (Clockwise)

Preceding gene: 85859283

Following gene: 85859286

Centisome position: 46.21

GC content: 47.52

Gene sequence:

>585_bases
ATGAAACGACATCCACTGGTATCCGCCGGCGAAAAAATCTATAACCTGCCTAACATCATCACCATGTTGAGAATCGGGGT
GATTCCTGCTCTCTTTTTTCTGCTGACTTCACCAGGCGCTACATGGAGCCTGGTGATTGCTTTTCTGTTTATTACCGCAG
CGCTGACCGATCTTCTGGATGGCTACATTGCAAGAAAATACGGGATTGTTACGACGATGGGAAAGTTTCTGGATCCCATC
GCCGACAAGCTGATCGTCAATACCGCCATGATTCTCATGATTCCGATCGGCCGCATTCCTGCCTGGATTGTGGCAATTAC
GATTATCCGCGATATCGCCGTGGACGGCATGAGAAGCATCGCATCGGGAGAAGGAATGGTTATTGATGCAAGCAGTCTGG
GAAAGAGAAAAACCCTCTGCCAGACCATTGCCGTCTCGGCATTGATTATTCACTATCAATTTCTGGGACTCAACGCTCAT
GCGGTGGGTATCGTGATTCTTTATATTGCCCTTTTGCTGACGGTGTATTCCGGATTGGATTACTTCATGCAATTTTATCA
GTGCGCCATCCGCAATAAAGAATAG

Upstream 100 bases:

>100_bases
TCGATCTGTTTCTGGCTGACTGGGAAAAAGTTCCTAAACTCAAAAAATGACTTTGCTTATGTGTTCCAGATTTGCTGTGA
TCTGAAACCTTCAGAAAATT

Downstream 100 bases:

>100_bases
GTCAATTAATCGACCATCCTTTCCCGACTAATCTTCCAAGCATTTCCGATCTTTATAAGCCGCAGCTCTTTTGTGCCCGT
TTCGTTCATTCCAGGGGCGG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKRHPLVSAGEKIYNLPNIITMLRIGVIPALFFLLTSPGATWSLVIAFLFITAALTDLLDGYIARKYGIVTTMGKFLDPI
ADKLIVNTAMILMIPIGRIPAWIVAITIIRDIAVDGMRSIASGEGMVIDASSLGKRKTLCQTIAVSALIIHYQFLGLNAH
AVGIVILYIALLLTVYSGLDYFMQFYQCAIRNKE

Sequences:

>Translated_194_residues
MKRHPLVSAGEKIYNLPNIITMLRIGVIPALFFLLTSPGATWSLVIAFLFITAALTDLLDGYIARKYGIVTTMGKFLDPI
ADKLIVNTAMILMIPIGRIPAWIVAITIIRDIAVDGMRSIASGEGMVIDASSLGKRKTLCQTIAVSALIIHYQFLGLNAH
AVGIVILYIALLLTVYSGLDYFMQFYQCAIRNKE
>Mature_194_residues
MKRHPLVSAGEKIYNLPNIITMLRIGVIPALFFLLTSPGATWSLVIAFLFITAALTDLLDGYIARKYGIVTTMGKFLDPI
ADKLIVNTAMILMIPIGRIPAWIVAITIIRDIAVDGMRSIASGEGMVIDASSLGKRKTLCQTIAVSALIIHYQFLGLNAH
AVGIVILYIALLLTVYSGLDYFMQFYQCAIRNKE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=175, Percent_Identity=33.1428571428571, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71984834, Length=106, Percent_Identity=39.622641509434, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71984838, Length=106, Percent_Identity=39.622641509434, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320059, Length=105, Percent_Identity=42.8571428571429, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21291; Mature: 21291

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRHPLVSAGEKIYNLPNIITMLRIGVIPALFFLLTSPGATWSLVIAFLFITAALTDLLD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GYIARKYGIVTTMGKFLDPIADKLIVNTAMILMIPIGRIPAWIVAITIIRDIAVDGMRSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGEGMVIDASSLGKRKTLCQTIAVSALIIHYQFLGLNAHAVGIVILYIALLLTVYSGLD
HCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YFMQFYQCAIRNKE
HHHHHHHHHHCCCC
>Mature Secondary Structure
MKRHPLVSAGEKIYNLPNIITMLRIGVIPALFFLLTSPGATWSLVIAFLFITAALTDLLD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GYIARKYGIVTTMGKFLDPIADKLIVNTAMILMIPIGRIPAWIVAITIIRDIAVDGMRSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGEGMVIDASSLGKRKTLCQTIAVSALIIHYQFLGLNAHAVGIVILYIALLLTVYSGLD
HCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YFMQFYQCAIRNKE
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]