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The map label for this gene is trpD [H]

Identifier: 85858282

GI number: 85858282

Start: 446005

End: 447351

Strand: Direct

Name: trpD [H]

Synonym: SYN_02590

Alternate gene names: 85858282

Gene position: 446005-447351 (Clockwise)

Preceding gene: 85858281

Following gene: 85858283

Centisome position: 14.03

GC content: 51.97

Gene sequence:

>1347_bases
ATGATCACTGCACTTGTTCTTTTCAGAGTGGAAAAAGGAAAAATTCAGCGCCTGGCCAACCAGCTGGGTGCCATCGAGGA
GGTCGTGGAGGTGCTTTCCATTACCGGGGAGTATGATCTCATGGCTAAGATCCAGGTCCAGGAATATGAAAGCCTTTCCG
ACATCGTGACAGATAAGATGCAGAACACGGAAGGTGTTTTGTCGACGAGGACAATGATGGCCTTCAAGACTTACAAATTC
CATGAGCTGGCAACTGGGGCTCCCAATGGAATGATGATCCCGCAATCATTGGAAGAGACGGCCTTGGCCATCGAGACCGG
CAAGAAGATGATCAAGCCGATTCTTGCCAAGCTGACGGAAAATTTTGATCTGGAAAAAAGTGAAATCAACAGTGTTATCG
ACGCCATCAATGCCGGAGAGCTGTCTGACGTCCAGATTGCCGGTTTTCTGGTTGGCATGCTGAGCAAGGGACCAAGTATC
AAGGAAGTTGCCTGCATCGCCCAAGCCATGCGCCGAAACTGCGTTCCCATTCATGTTTCAATTAAATCGGAACTTACCGA
TACCTGTGGTACCGGAGGCGGTTCGGCCACCTTCAATGTGAGCACGGCAAACGCCATCCTGACGGCCTCGGCTGGCGTTC
CGGTTGCCAAGCACGGCAGCCGTTCCATCTCATCTTCCTCGGGAAGCGCGGATGTTCTGGAGGCCCTTGGTGTCAATATT
GATCTCACACCAGAGCAGTCTGCCCGGCTGATTGAAGATATCGGGATCAGTTTCCTCTACGCGCCGAATTTTCATCCCGT
CATGCTCAAGGTATTCGGGCCGGAAAACCAACTCGGCATCAAGACGATTTTTTTCACGATCATCGGTCCGCTGATTAATC
CGCTGGGCGCCCGGAACCATACCATCGGCGTCTATAAACCGGAACTGGTCAGCATGATGGCCAACGTCGTGGCGGAAATG
GATTTCAACCACGTCATCGTGGCCCACGGCATTGATGGTTTGGATGAAATATCGCTGATCGGGAAAACCTCGCTGGCGGA
GATCAGAGGAAAAGAGATCAAATATTATGAAGTCACTCCTGATGATTTCGGCCTTAAACGCTGTACCCTGAACGATATTT
CCGGCGGATCGCCGGAATTCAACGCCCAGATCACCCGGAACATATTTTCAGGCGCGGAGCGTGGACCGAGAAGAGATTTC
CTCGTCCTGAACAATGCGGCAACGCTTTATGTCAGCGGCAAGGTGTCGAGCATCCGGGAGGGAATCGACCTGTCCCGTTC
TCTTATCGATTCGGGGGCCGCCTCGCGCAAACTCCAGGAATTCGTGGAAAAATCCCATAAGGTTTAA

Upstream 100 bases:

>100_bases
GTTTTTTTTCAGCCCCCTTTTTAAGAAAGGCTCAGCAGACGGCGTCGCGTGTGTCGTCGTGGTAAATTAACGTGTCATTT
AAAACAGGAGAACCAATCGG

Downstream 100 bases:

>100_bases
TAGGGTGCGGTCATGTTGAAAAAAGATGCTTCTGCGGGACAGGGACTAAGACTGTCTCTGTCCGCATCCATCCGGAAAAG
ACAAAGTGAGAAGTACTTTC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MITALVLFRVEKGKIQRLANQLGAIEEVVEVLSITGEYDLMAKIQVQEYESLSDIVTDKMQNTEGVLSTRTMMAFKTYKF
HELATGAPNGMMIPQSLEETALAIETGKKMIKPILAKLTENFDLEKSEINSVIDAINAGELSDVQIAGFLVGMLSKGPSI
KEVACIAQAMRRNCVPIHVSIKSELTDTCGTGGGSATFNVSTANAILTASAGVPVAKHGSRSISSSSGSADVLEALGVNI
DLTPEQSARLIEDIGISFLYAPNFHPVMLKVFGPENQLGIKTIFFTIIGPLINPLGARNHTIGVYKPELVSMMANVVAEM
DFNHVIVAHGIDGLDEISLIGKTSLAEIRGKEIKYYEVTPDDFGLKRCTLNDISGGSPEFNAQITRNIFSGAERGPRRDF
LVLNNAATLYVSGKVSSIREGIDLSRSLIDSGAASRKLQEFVEKSHKV

Sequences:

>Translated_448_residues
MITALVLFRVEKGKIQRLANQLGAIEEVVEVLSITGEYDLMAKIQVQEYESLSDIVTDKMQNTEGVLSTRTMMAFKTYKF
HELATGAPNGMMIPQSLEETALAIETGKKMIKPILAKLTENFDLEKSEINSVIDAINAGELSDVQIAGFLVGMLSKGPSI
KEVACIAQAMRRNCVPIHVSIKSELTDTCGTGGGSATFNVSTANAILTASAGVPVAKHGSRSISSSSGSADVLEALGVNI
DLTPEQSARLIEDIGISFLYAPNFHPVMLKVFGPENQLGIKTIFFTIIGPLINPLGARNHTIGVYKPELVSMMANVVAEM
DFNHVIVAHGIDGLDEISLIGKTSLAEIRGKEIKYYEVTPDDFGLKRCTLNDISGGSPEFNAQITRNIFSGAERGPRRDF
LVLNNAATLYVSGKVSSIREGIDLSRSLIDSGAASRKLQEFVEKSHKV
>Mature_448_residues
MITALVLFRVEKGKIQRLANQLGAIEEVVEVLSITGEYDLMAKIQVQEYESLSDIVTDKMQNTEGVLSTRTMMAFKTYKF
HELATGAPNGMMIPQSLEETALAIETGKKMIKPILAKLTENFDLEKSEINSVIDAINAGELSDVQIAGFLVGMLSKGPSI
KEVACIAQAMRRNCVPIHVSIKSELTDTCGTGGGSATFNVSTANAILTASAGVPVAKHGSRSISSSSGSADVLEALGVNI
DLTPEQSARLIEDIGISFLYAPNFHPVMLKVFGPENQLGIKTIFFTIIGPLINPLGARNHTIGVYKPELVSMMANVVAEM
DFNHVIVAHGIDGLDEISLIGKTSLAEIRGKEIKYYEVTPDDFGLKRCTLNDISGGSPEFNAQITRNIFSGAERGPRRDF
LVLNNAATLYVSGKVSSIREGIDLSRSLIDSGAASRKLQEFVEKSHKV

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=316, Percent_Identity=35.7594936708861, Blast_Score=174, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6320561, Length=271, Percent_Identity=33.210332103321, Blast_Score=121, Evalue=3e-28,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 48324; Mature: 48324

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITALVLFRVEKGKIQRLANQLGAIEEVVEVLSITGEYDLMAKIQVQEYESLSDIVTDKM
CCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHH
QNTEGVLSTRTMMAFKTYKFHELATGAPNGMMIPQSLEETALAIETGKKMIKPILAKLTE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NFDLEKSEINSVIDAINAGELSDVQIAGFLVGMLSKGPSIKEVACIAQAMRRNCVPIHVS
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEE
IKSELTDTCGTGGGSATFNVSTANAILTASAGVPVAKHGSRSISSSSGSADVLEALGVNI
EHHHHHHHCCCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCE
DLTPEQSARLIEDIGISFLYAPNFHPVMLKVFGPENQLGIKTIFFTIIGPLINPLGARNH
EECCHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCC
TIGVYKPELVSMMANVVAEMDFNHVIVAHGIDGLDEISLIGKTSLAEIRGKEIKYYEVTP
EEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCHHHHHCCCEEEEEEECC
DDFGLKRCTLNDISGGSPEFNAQITRNIFSGAERGPRRDFLVLNNAATLYVSGKVSSIRE
CCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCHHHHHH
GIDLSRSLIDSGAASRKLQEFVEKSHKV
HHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITALVLFRVEKGKIQRLANQLGAIEEVVEVLSITGEYDLMAKIQVQEYESLSDIVTDKM
CCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHH
QNTEGVLSTRTMMAFKTYKFHELATGAPNGMMIPQSLEETALAIETGKKMIKPILAKLTE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NFDLEKSEINSVIDAINAGELSDVQIAGFLVGMLSKGPSIKEVACIAQAMRRNCVPIHVS
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEE
IKSELTDTCGTGGGSATFNVSTANAILTASAGVPVAKHGSRSISSSSGSADVLEALGVNI
EHHHHHHHCCCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCE
DLTPEQSARLIEDIGISFLYAPNFHPVMLKVFGPENQLGIKTIFFTIIGPLINPLGARNH
EECCHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCC
TIGVYKPELVSMMANVVAEMDFNHVIVAHGIDGLDEISLIGKTSLAEIRGKEIKYYEVTP
EEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCHHHHHCCCEEEEEEECC
DDFGLKRCTLNDISGGSPEFNAQITRNIFSGAERGPRRDFLVLNNAATLYVSGKVSSIRE
CCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCHHHHHH
GIDLSRSLIDSGAASRKLQEFVEKSHKV
HHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA