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The map label for this gene is ctaD [H]

Identifier: 85373373

GI number: 85373373

Start: 582570

End: 584273

Strand: Direct

Name: ctaD [H]

Synonym: ELI_02730

Alternate gene names: 85373373

Gene position: 582570-584273 (Clockwise)

Preceding gene: 85373372

Following gene: 85373374

Centisome position: 19.09

GC content: 61.09

Gene sequence:

>1704_bases
ATGGCAACCACCGCAGAAGGCTTTGACGTCCATACCGACGATCACGCGCATGACGCGGACCACAAACCGGGCTTTTTCGC
CCGCTGGTTCATGTCGACCAACCACAAGGATATCGGCACGCTGTACCTGCTGTTCGCGATCGTCGCGGGCCTCGTCGGCG
GTACGATGTCGGGCGTGATGCGCGCCGAACTTGCCGAGCCGGGCATCCAGTATCTCGGCTGGTGGGTCGAATTCTTCGGC
GGCGAAGCGAGCTTCGACACCAATCTGCATATGTGGAACGTGTTCATCACCGCTCACGGCCTGATCATGGTCTTCTTCAT
GGTCATGCCGGCGATGATCGGCGGCTTCGGGAACTGGTTCGTGCCGCTGATGATTGGCGCGCCGGACATGGCCTTCCCGC
GCATGAACAACATCTCATTCTGGCTCACCGTGGCCGGTTTCCTCAGCCTCTGTTTCTCACTGTTCGTGCCCGGTGGCACG
GGTCTTGGCGCAGGCGTGGGCTGGACCGTTTATGCACCGCTGTCGACCACCGGCTCGCAAGGGCCCGCCGTCGACTTTGC
GATCTTCTCGCTGCACCTTGCAGGCGCGGGCTCGATCCTGGGTGCGACCAACTTCATCACCACCATCTTCAACATGCGTG
CGCCGGGCATGACCCTGCACAAGATGCCTCTGTTCGTATGGTCGGTGCTTGTCACCGCCTTCCTGCTGCTGCTGGCGCTG
CCTGTTCTGGCCGCAGCCATCACCATGTTGCTGACCGACCGTAACTTCGGCACGACCTTCTTCGATCCGGCCGGTGGCGG
CGACCCGGTGCTCTACCAGCACCTGTTCTGGTTCTTCGGCCACCCGGAGGTCTACATCATGATCCTGCCGGGCTTCGGCA
TGGTCTCGCAGATCGTCGCTACCTTCAGCCGTAAGCCGGTCTTCGGGTATCTCGGCATGGCCTACGCCATGGTCGCGATC
GGCGTCGTCGGCTTCATCGTGTGGGCGCACCACATGTATACCGTCGGCCTCAGCGTGAACACGAAGATGTACTTCACCGC
GGCCACCATGGTGATCGCCGTGCCGACCGGTGTGAAGATTTTCAGCTGGATCGCCACGATGTGGGGCGGCTCGATGGAGT
TCAAGTCACCCATGGTCTGGGCGCTCGGCTTCATCTTCCTCTTCACCGTGGGCGGTGTGACCGGCGTCGTGCTGGCCAAT
GGCGGTATCGACGACAACCTGCACGATACCTACTACGTGGTGGCGCATTTCCACTACGTGCTGTCGATGGGTGCGGTTTT
CTCGATCTTCGCCGGTTTCTACTACTGGTTCCCGAAGATGAGCGGTCGCTGGCACAGCGAATTCCTCAGCCACGTCCACT
TCTGGCTGTTCTTCATCGGCGTGAACATCGTCTTCTTCCCGATGCACTTCCTCGGGATGCAGGGCATGCCGCGCCGCTAT
CCGGACTATACCGCAGCCTATGCTTACTGGAACGAGATCGCGACGATGGGCTATTACGTCGTCTTCGCTTCGGTGATCGT
GTTCCTCGTCAACATCGGCTACGCGCTCGTCGCCGGTCGCCGGGCGGAAGCAAACTACTGGGGCGAAGGCGCAACGACGC
TCGAATGGAGCCTGTCGAGCCCGCCGCCGTTCCACCAGTACGAAACCCTGCCGGTGATCGAGGACCACCACGATTACCAC
CACCAGCTGCCCTCCAAAGGATAA

Upstream 100 bases:

>100_bases
CTGCTACAGATGCCGCCTCTACCGAAGGCGGTAGTGACGCTGCAGCCGCCGAATAATAGACCGACGACAAGAATTCACGC
GAAAGAAGAGACCGAAAACG

Downstream 100 bases:

>100_bases
CGCCCCGGGCAGAGGGTAGGGCTGGCCCGACAACCAGATCGAGAGGGGGCGCATCGGCAACGGTGCGCCCTTCTTTCAAG
AAAGACCGCAACGGAACCGA

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MATTAEGFDVHTDDHAHDADHKPGFFARWFMSTNHKDIGTLYLLFAIVAGLVGGTMSGVMRAELAEPGIQYLGWWVEFFG
GEASFDTNLHMWNVFITAHGLIMVFFMVMPAMIGGFGNWFVPLMIGAPDMAFPRMNNISFWLTVAGFLSLCFSLFVPGGT
GLGAGVGWTVYAPLSTTGSQGPAVDFAIFSLHLAGAGSILGATNFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLLAL
PVLAAAITMLLTDRNFGTTFFDPAGGGDPVLYQHLFWFFGHPEVYIMILPGFGMVSQIVATFSRKPVFGYLGMAYAMVAI
GVVGFIVWAHHMYTVGLSVNTKMYFTAATMVIAVPTGVKIFSWIATMWGGSMEFKSPMVWALGFIFLFTVGGVTGVVLAN
GGIDDNLHDTYYVVAHFHYVLSMGAVFSIFAGFYYWFPKMSGRWHSEFLSHVHFWLFFIGVNIVFFPMHFLGMQGMPRRY
PDYTAAYAYWNEIATMGYYVVFASVIVFLVNIGYALVAGRRAEANYWGEGATTLEWSLSSPPPFHQYETLPVIEDHHDYH
HQLPSKG

Sequences:

>Translated_567_residues
MATTAEGFDVHTDDHAHDADHKPGFFARWFMSTNHKDIGTLYLLFAIVAGLVGGTMSGVMRAELAEPGIQYLGWWVEFFG
GEASFDTNLHMWNVFITAHGLIMVFFMVMPAMIGGFGNWFVPLMIGAPDMAFPRMNNISFWLTVAGFLSLCFSLFVPGGT
GLGAGVGWTVYAPLSTTGSQGPAVDFAIFSLHLAGAGSILGATNFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLLAL
PVLAAAITMLLTDRNFGTTFFDPAGGGDPVLYQHLFWFFGHPEVYIMILPGFGMVSQIVATFSRKPVFGYLGMAYAMVAI
GVVGFIVWAHHMYTVGLSVNTKMYFTAATMVIAVPTGVKIFSWIATMWGGSMEFKSPMVWALGFIFLFTVGGVTGVVLAN
GGIDDNLHDTYYVVAHFHYVLSMGAVFSIFAGFYYWFPKMSGRWHSEFLSHVHFWLFFIGVNIVFFPMHFLGMQGMPRRY
PDYTAAYAYWNEIATMGYYVVFASVIVFLVNIGYALVAGRRAEANYWGEGATTLEWSLSSPPPFHQYETLPVIEDHHDYH
HQLPSKG
>Mature_566_residues
ATTAEGFDVHTDDHAHDADHKPGFFARWFMSTNHKDIGTLYLLFAIVAGLVGGTMSGVMRAELAEPGIQYLGWWVEFFGG
EASFDTNLHMWNVFITAHGLIMVFFMVMPAMIGGFGNWFVPLMIGAPDMAFPRMNNISFWLTVAGFLSLCFSLFVPGGTG
LGAGVGWTVYAPLSTTGSQGPAVDFAIFSLHLAGAGSILGATNFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLLALP
VLAAAITMLLTDRNFGTTFFDPAGGGDPVLYQHLFWFFGHPEVYIMILPGFGMVSQIVATFSRKPVFGYLGMAYAMVAIG
VVGFIVWAHHMYTVGLSVNTKMYFTAATMVIAVPTGVKIFSWIATMWGGSMEFKSPMVWALGFIFLFTVGGVTGVVLANG
GIDDNLHDTYYVVAHFHYVLSMGAVFSIFAGFYYWFPKMSGRWHSEFLSHVHFWLFFIGVNIVFFPMHFLGMQGMPRRYP
DYTAAYAYWNEIATMGYYVVFASVIVFLVNIGYALVAGRRAEANYWGEGATTLEWSLSSPPPFHQYETLPVIEDHHDYHH
QLPSKG

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=526, Percent_Identity=59.8859315589354, Blast_Score=580, Evalue=1e-165,
Organism=Escherichia coli, GI1786634, Length=544, Percent_Identity=42.0955882352941, Blast_Score=385, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6226519, Length=549, Percent_Identity=53.0054644808743, Blast_Score=578, Evalue=1e-166,
Organism=Saccharomyces cerevisiae, GI6226524, Length=339, Percent_Identity=58.1120943952802, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6226523, Length=264, Percent_Identity=53.4090909090909, Blast_Score=253, Evalue=4e-68,
Organism=Saccharomyces cerevisiae, GI6226522, Length=93, Percent_Identity=40.8602150537634, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 62769; Mature: 62638

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTAEGFDVHTDDHAHDADHKPGFFARWFMSTNHKDIGTLYLLFAIVAGLVGGTMSGVM
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RAELAEPGIQYLGWWVEFFGGEASFDTNLHMWNVFITAHGLIMVFFMVMPAMIGGFGNWF
HHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCE
VPLMIGAPDMAFPRMNNISFWLTVAGFLSLCFSLFVPGGTGLGAGVGWTVYAPLSTTGSQ
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
GPAVDFAIFSLHLAGAGSILGATNFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLLAL
CCCHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PVLAAAITMLLTDRNFGTTFFDPAGGGDPVLYQHLFWFFGHPEVYIMILPGFGMVSQIVA
HHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
TFSRKPVFGYLGMAYAMVAIGVVGFIVWAHHMYTVGLSVNTKMYFTAATMVIAVPTGVKI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEEEEEEEEEEECCCHHH
FSWIATMWGGSMEFKSPMVWALGFIFLFTVGGVTGVVLANGGIDDNLHDTYYVVAHFHYV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
LSMGAVFSIFAGFYYWFPKMSGRWHSEFLSHVHFWLFFIGVNIVFFPMHFLGMQGMPRRY
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PDYTAAYAYWNEIATMGYYVVFASVIVFLVNIGYALVAGRRAEANYWGEGATTLEWSLSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCC
PPPFHQYETLPVIEDHHDYHHQLPSKG
CCCCCCCCCCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure 
ATTAEGFDVHTDDHAHDADHKPGFFARWFMSTNHKDIGTLYLLFAIVAGLVGGTMSGVM
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RAELAEPGIQYLGWWVEFFGGEASFDTNLHMWNVFITAHGLIMVFFMVMPAMIGGFGNWF
HHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCE
VPLMIGAPDMAFPRMNNISFWLTVAGFLSLCFSLFVPGGTGLGAGVGWTVYAPLSTTGSQ
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
GPAVDFAIFSLHLAGAGSILGATNFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLLAL
CCCHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PVLAAAITMLLTDRNFGTTFFDPAGGGDPVLYQHLFWFFGHPEVYIMILPGFGMVSQIVA
HHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
TFSRKPVFGYLGMAYAMVAIGVVGFIVWAHHMYTVGLSVNTKMYFTAATMVIAVPTGVKI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEEEEEEEEEEECCCHHH
FSWIATMWGGSMEFKSPMVWALGFIFLFTVGGVTGVVLANGGIDDNLHDTYYVVAHFHYV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
LSMGAVFSIFAGFYYWFPKMSGRWHSEFLSHVHFWLFFIGVNIVFFPMHFLGMQGMPRRY
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PDYTAAYAYWNEIATMGYYVVFASVIVFLVNIGYALVAGRRAEANYWGEGATTLEWSLSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCC
PPPFHQYETLPVIEDHHDYHHQLPSKG
CCCCCCCCCCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]