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The map label for this gene is ctaC [H]

Identifier: 85373372

GI number: 85373372

Start: 581413

End: 582525

Strand: Direct

Name: ctaC [H]

Synonym: ELI_02725

Alternate gene names: 85373372

Gene position: 581413-582525 (Clockwise)

Preceding gene: 85373362

Following gene: 85373373

Centisome position: 19.05

GC content: 62.08

Gene sequence:

>1113_bases
ATGGGAAGCGTCGAAAAGATGATCACCGCCACCAGGCTCCGTGAAACCACCCACGCCATCGCGCTGCTGTTTGCCGCGCT
GCTGCTGGCTTTCGGCGCGCAGGCGGCGCTCGCGACAATTGCCGCCCCGACGCAGCCCGATGCAACGACGCCGGAAAGCG
CGATGCCGGGTGAAACCGACCCGGTCACGGCGGAAGAAGCGGCGGCTGCCGATTCGAGCATCCCCGGCTACGAACCGCTC
GGCCCCGAAATGATCAAGGGCCAGCCGACCGCCTTCGAAGACGATGCGCTCAAGAGCATGACGTTCCAGGACCAGTACAA
CGCCAACGGCGAATATGCGCTGTGGATGCATGACGCGATCCTGATGCCGATCATCACGATCATCAGCCTGTTCGTCCTCG
GCCTGCTACTGTGGGTGGTCGTTCGCTATCGTCGTGGTGCCAATCCGGTAGCTTCCAAGACAACGCACAATACGCTGATC
GAGGTCGTCTGGACCGTGATCCCCATCATCATCCTGCTGGTTATCGCTGTCCCGTCGATCTCGCTGCTGGCAAAACAGTA
TGAAACCCCGCCGAAGGACGCGATTACGATCAAGGCGACCGGTTACCAGTGGTATTGGGGTTATACCTATCCCGACCAGG
GCGGCTTCGAGATTATTTCCAACATGCTCGACGAGGCCGACGCGATGGACAGAGGCCTGCCCGGGCAGTTGGCGGTCGAC
AACCGCATGGTCGTGCCGGTCGGCGTGCCGCTCCGCATCCAGACGACGGCGGCTGACGTGATCCACTCCTTCGCTCTGCC
GAGCCTGTGGTTCAAGAACGACGCCGTTCCCGGTCGCATCAACGAAAAGATGCTGATCATCGACGAGCCCGGTATCTATT
ACGGCCAGTGTTCCGAATTGTGCGGCGCCCGCCACGGCTATATGCCGATCGCGGTCGAAGCGGTCCCGATGGACCAGTGG
CGCGCATGGGTGATCGGGCAGGGCGGCAGCTTCGAAGATGCCGAAGTGGCTGCCGACGCGCGCGAGGAAGTCATCAATGC
GCAGGATGGCGACGCAGCTGCTACAGATGCCGCCTCTACCGAAGGCGGTAGTGACGCTGCAGCCGCCGAATAA

Upstream 100 bases:

>100_bases
CTAGGGACGCTTGTGACTATCGGCAAGCGCGCGTATAGCGCGCCGCAAATGCCCCTTGATGGGCCGGTTCGGCTGCCAGT
GGGGTGGCCATAAACGCAAC

Downstream 100 bases:

>100_bases
TAGACCGACGACAAGAATTCACGCGAAAGAAGAGACCGAAAACGATGGCAACCACCGCAGAAGGCTTTGACGTCCATACC
GACGATCACGCGCATGACGC

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MGSVEKMITATRLRETTHAIALLFAALLLAFGAQAALATIAAPTQPDATTPESAMPGETDPVTAEEAAAADSSIPGYEPL
GPEMIKGQPTAFEDDALKSMTFQDQYNANGEYALWMHDAILMPIITIISLFVLGLLLWVVVRYRRGANPVASKTTHNTLI
EVVWTVIPIIILLVIAVPSISLLAKQYETPPKDAITIKATGYQWYWGYTYPDQGGFEIISNMLDEADAMDRGLPGQLAVD
NRMVVPVGVPLRIQTTAADVIHSFALPSLWFKNDAVPGRINEKMLIIDEPGIYYGQCSELCGARHGYMPIAVEAVPMDQW
RAWVIGQGGSFEDAEVAADAREEVINAQDGDAAATDAASTEGGSDAAAAE

Sequences:

>Translated_370_residues
MGSVEKMITATRLRETTHAIALLFAALLLAFGAQAALATIAAPTQPDATTPESAMPGETDPVTAEEAAAADSSIPGYEPL
GPEMIKGQPTAFEDDALKSMTFQDQYNANGEYALWMHDAILMPIITIISLFVLGLLLWVVVRYRRGANPVASKTTHNTLI
EVVWTVIPIIILLVIAVPSISLLAKQYETPPKDAITIKATGYQWYWGYTYPDQGGFEIISNMLDEADAMDRGLPGQLAVD
NRMVVPVGVPLRIQTTAADVIHSFALPSLWFKNDAVPGRINEKMLIIDEPGIYYGQCSELCGARHGYMPIAVEAVPMDQW
RAWVIGQGGSFEDAEVAADAREEVINAQDGDAAATDAASTEGGSDAAAAE
>Mature_369_residues
GSVEKMITATRLRETTHAIALLFAALLLAFGAQAALATIAAPTQPDATTPESAMPGETDPVTAEEAAAADSSIPGYEPLG
PEMIKGQPTAFEDDALKSMTFQDQYNANGEYALWMHDAILMPIITIISLFVLGLLLWVVVRYRRGANPVASKTTHNTLIE
VVWTVIPIIILLVIAVPSISLLAKQYETPPKDAITIKATGYQWYWGYTYPDQGGFEIISNMLDEADAMDRGLPGQLAVDN
RMVVPVGVPLRIQTTAADVIHSFALPSLWFKNDAVPGRINEKMLIIDEPGIYYGQCSELCGARHGYMPIAVEAVPMDQWR
AWVIGQGGSFEDAEVAADAREEVINAQDGDAAATDAASTEGGSDAAAAE

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=158, Percent_Identity=46.2025316455696, Blast_Score=155, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6226540, Length=231, Percent_Identity=42.4242424242424, Blast_Score=165, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 39740; Mature: 39608

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSVEKMITATRLRETTHAIALLFAALLLAFGAQAALATIAAPTQPDATTPESAMPGETD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
PVTAEEAAAADSSIPGYEPLGPEMIKGQPTAFEDDALKSMTFQDQYNANGEYALWMHDAI
CCCHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEHHHH
LMPIITIISLFVLGLLLWVVVRYRRGANPVASKTTHNTLIEVVWTVIPIIILLVIAVPSI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
SLLAKQYETPPKDAITIKATGYQWYWGYTYPDQGGFEIISNMLDEADAMDRGLPGQLAVD
HHHHHHHCCCCCCEEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEC
NRMVVPVGVPLRIQTTAADVIHSFALPSLWFKNDAVPGRINEKMLIIDEPGIYYGQCSEL
CEEEEEECCCEEEEHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHH
CGARHGYMPIAVEAVPMDQWRAWVIGQGGSFEDAEVAADAREEVINAQDGDAAATDAAST
HCCCCCCCEEEEEEEEHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCC
EGGSDAAAAE
CCCCCCCCCC
>Mature Secondary Structure 
GSVEKMITATRLRETTHAIALLFAALLLAFGAQAALATIAAPTQPDATTPESAMPGETD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
PVTAEEAAAADSSIPGYEPLGPEMIKGQPTAFEDDALKSMTFQDQYNANGEYALWMHDAI
CCCHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEHHHH
LMPIITIISLFVLGLLLWVVVRYRRGANPVASKTTHNTLIEVVWTVIPIIILLVIAVPSI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
SLLAKQYETPPKDAITIKATGYQWYWGYTYPDQGGFEIISNMLDEADAMDRGLPGQLAVD
HHHHHHHCCCCCCEEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEC
NRMVVPVGVPLRIQTTAADVIHSFALPSLWFKNDAVPGRINEKMLIIDEPGIYYGQCSEL
CEEEEEECCCEEEEHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHH
CGARHGYMPIAVEAVPMDQWRAWVIGQGGSFEDAEVAADAREEVINAQDGDAAATDAAST
HCCCCCCCEEEEEEEEHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCC
EGGSDAAAAE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2820725; 7651515; 9380672 [H]