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The map label for this gene is ptrB [H]

Identifier: 84625427

GI number: 84625427

Start: 4261674

End: 4263884

Strand: Reverse

Name: ptrB [H]

Synonym: XOO_3770

Alternate gene names: 84625427

Gene position: 4263884-4261674 (Counterclockwise)

Preceding gene: 84625429

Following gene: 84625426

Centisome position: 86.31

GC content: 61.06

Gene sequence:

>2211_bases
ATGACGCCCGGTAACGGGCTCTTCCACACTCAAGTGCTGGGATGGCATTGCGTTCATCCGACGGACCCCAATCTGATGAA
GCACGCCCTCACTCTTCTGATCGCCAGCCTGATGACCATATCTCCCGCCTTCGCCGCCCCTCCTTCGCCACCAGGCGTCG
CCAAGCACCCGCATGTGGTCAAGGCGCCGTTCGGCGCGACCCGCAACGACGACTATTACTGGTTGCGTGACGACAAGCGC
GAAGACAAGGCGATGCTGGCCTATCTCAACGCCGAGAATGCCTACGCCGACAAGGTGATGGCGCCGTTGAAGCCGTTGGA
AGAGACGCTGTATACCGAGATCGTCGGGCGCATCAAGCAGGACGACGCCAGCGTGCCATATCGCGAGCGCGGCTACTGGT
ATTACACCCGGTTCGAAACCGGCAAGGACTATCCGATCCAGGCGCGCCGCAAGGGCAGCATGGACGCGCCGGAAGAGATC
CTGCTCGATGTGAACCAGTTGGCGGAAGGCAAGGGCTATTTCAGCGTCGGCGATGCCAAAGTGAGCCAGGACAACCGCAT
CCTGGCCTGGGTCGACGATGCCGTCGGCCGCCGTCAATACACCATCCGTTTCAAGAATCTGGACACCGGCGAACGCTATC
CGGACACCGTGGAAGGCGTGTCGCCCAATGTGGTCTGGGCCGACGACAACAAGACGCTGTTCTACGTCGAAAACGACCCG
GAAACGCTGCTCACCGTGCGCGTGAAAAAGCACGTGCTGGGGACCTCTTCCAAGGACGATGTGCTGGTGTATGAAGAGAA
AGACGACAGCTTCTACATGAGCATCGGCCGCACCCGCGACGACAAGTACATCACTATTGGTGTAGAAAGCACGGTGTCTT
CGGAAACGCGCTATGCGCTGGCTGCCAAGCCGGACACCTTCAAGGTGCTGGCCAAGCGCGAGCGCGATGTGGAATACCAC
GCCGAGCATTTCGATGGCCGCTGGGTGATCCGCACCAATGCCGATGACGCCAGGAACTTCAAGCTGGTCACCGCGCCGAC
CGATGCGACCACGCGCAAGCAGTGGACCGATTGGGTGGCGCACGACGACAGCGTCTACATCGAAAACTTCGAGTTGTTCG
ATGGGTTCACCGCCATCGAGGAACGTTCCGGCGGATTGGAGCGCGTGCGCCTGCAATTCAACAGTCCGCACATGGACGTG
CGGGCTCTTGCGGGGGAGCCGCAATACGTCAAGGCCGACGAACCAGCGTATTCGATGGGGTTGTCGGTCAACTCCGAACC
CGACACCCCCTGGTTGCGCTACAGCTACACCTCGCTGACCACGCCGGCGACCACCTACGAGCTCAACACGCAGACCGGCG
AGCGCAAGTTGCTCAAGCAGCAACCGGTGATCGGCTACGACGCCAGCAAGTATGTGACCGAACGCGTGTGGGTGACCGCG
CGCGACGGTGTCAAGGTGCCGGTGTCGCTGGTCTATAAAAAAGGCTTCAAGAAGGACGGCAGCGCAGCGTTGTTCCAGTA
CGCGTATGGCAGCTACGGCATGTCGATGGACCCGGTATTCAATCTGCCGGTGATCAGTCTGCTGGACCGCGGCGTGGTGT
ATGCCATCGCGCATATCCGCGGCGGCCAGGAAATGGGCCGTCAGTGGTACGACGACGGCAAGCTGCTGCATAAGAAGAAC
ACCTTCAACGATTTTATCGATGTGACCCGCGGCCTGGTTGCACAGGGCTACGCCGCCAAGGACCGCGTGGCCGCGTCCGG
TGGCAGCGCGGGCGGCCTGTTGATGGGCGCGGTGGCCAATATGGCTCCGCAGGATTACCGGGTGATGGTCGCGCAGGTGC
CGTTTGTCGATGTGGTCACCACCATGCTGGATGCCAGCATTCCGCTCACCACCAACGAATACGACGAGTGGGGCAACCCG
GAAACCAAGGACTATTACGACTACATGCTGTCGTATTCGCCGTACGACAACGTGCGCAAGCAGGCGTACCCGGCGCTGTT
CGTCGGCACCGGCCTGTGGGATTCGCAGGTGCAGTATTGGGAGCCGGCCAAGTGGGTGGCCAAGCTGCGCGACGACAATA
CGGGCACGCAGCCGATTGTGTTCCGCACCAACATGGAAGCTGGGCATGGCGGCAAATCCGGCCGTTTCCGGCGCTATCGC
GAGCTGGCCGAGTCGTATGCGTTCGTGCTGGATCAGTTGGGCGTGAAGTAA

Upstream 100 bases:

>100_bases
TGTCCTGGCTGCGGCGGCTGTAGCCGCCTGCGTACGGAAGTCTGGAATCCATCGTTTCGATGATAAACCACCATGACCTA
GGACACATGACCTAGGACAC

Downstream 100 bases:

>100_bases
CTGGAAGACTGGGCTTGGGGAGTCGGGATTTGGGATTCGCTGGAGCGGATGGCTTGGGGCTTGGGAGCGAGCTGCCCGTT
CGGACGTGTGCGACTGGCAT

Product: protease II

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 736; Mature: 735

Protein sequence:

>736_residues
MTPGNGLFHTQVLGWHCVHPTDPNLMKHALTLLIASLMTISPAFAAPPSPPGVAKHPHVVKAPFGATRNDDYYWLRDDKR
EDKAMLAYLNAENAYADKVMAPLKPLEETLYTEIVGRIKQDDASVPYRERGYWYYTRFETGKDYPIQARRKGSMDAPEEI
LLDVNQLAEGKGYFSVGDAKVSQDNRILAWVDDAVGRRQYTIRFKNLDTGERYPDTVEGVSPNVVWADDNKTLFYVENDP
ETLLTVRVKKHVLGTSSKDDVLVYEEKDDSFYMSIGRTRDDKYITIGVESTVSSETRYALAAKPDTFKVLAKRERDVEYH
AEHFDGRWVIRTNADDARNFKLVTAPTDATTRKQWTDWVAHDDSVYIENFELFDGFTAIEERSGGLERVRLQFNSPHMDV
RALAGEPQYVKADEPAYSMGLSVNSEPDTPWLRYSYTSLTTPATTYELNTQTGERKLLKQQPVIGYDASKYVTERVWVTA
RDGVKVPVSLVYKKGFKKDGSAALFQYAYGSYGMSMDPVFNLPVISLLDRGVVYAIAHIRGGQEMGRQWYDDGKLLHKKN
TFNDFIDVTRGLVAQGYAAKDRVAASGGSAGGLLMGAVANMAPQDYRVMVAQVPFVDVVTTMLDASIPLTTNEYDEWGNP
ETKDYYDYMLSYSPYDNVRKQAYPALFVGTGLWDSQVQYWEPAKWVAKLRDDNTGTQPIVFRTNMEAGHGGKSGRFRRYR
ELAESYAFVLDQLGVK

Sequences:

>Translated_736_residues
MTPGNGLFHTQVLGWHCVHPTDPNLMKHALTLLIASLMTISPAFAAPPSPPGVAKHPHVVKAPFGATRNDDYYWLRDDKR
EDKAMLAYLNAENAYADKVMAPLKPLEETLYTEIVGRIKQDDASVPYRERGYWYYTRFETGKDYPIQARRKGSMDAPEEI
LLDVNQLAEGKGYFSVGDAKVSQDNRILAWVDDAVGRRQYTIRFKNLDTGERYPDTVEGVSPNVVWADDNKTLFYVENDP
ETLLTVRVKKHVLGTSSKDDVLVYEEKDDSFYMSIGRTRDDKYITIGVESTVSSETRYALAAKPDTFKVLAKRERDVEYH
AEHFDGRWVIRTNADDARNFKLVTAPTDATTRKQWTDWVAHDDSVYIENFELFDGFTAIEERSGGLERVRLQFNSPHMDV
RALAGEPQYVKADEPAYSMGLSVNSEPDTPWLRYSYTSLTTPATTYELNTQTGERKLLKQQPVIGYDASKYVTERVWVTA
RDGVKVPVSLVYKKGFKKDGSAALFQYAYGSYGMSMDPVFNLPVISLLDRGVVYAIAHIRGGQEMGRQWYDDGKLLHKKN
TFNDFIDVTRGLVAQGYAAKDRVAASGGSAGGLLMGAVANMAPQDYRVMVAQVPFVDVVTTMLDASIPLTTNEYDEWGNP
ETKDYYDYMLSYSPYDNVRKQAYPALFVGTGLWDSQVQYWEPAKWVAKLRDDNTGTQPIVFRTNMEAGHGGKSGRFRRYR
ELAESYAFVLDQLGVK
>Mature_735_residues
TPGNGLFHTQVLGWHCVHPTDPNLMKHALTLLIASLMTISPAFAAPPSPPGVAKHPHVVKAPFGATRNDDYYWLRDDKRE
DKAMLAYLNAENAYADKVMAPLKPLEETLYTEIVGRIKQDDASVPYRERGYWYYTRFETGKDYPIQARRKGSMDAPEEIL
LDVNQLAEGKGYFSVGDAKVSQDNRILAWVDDAVGRRQYTIRFKNLDTGERYPDTVEGVSPNVVWADDNKTLFYVENDPE
TLLTVRVKKHVLGTSSKDDVLVYEEKDDSFYMSIGRTRDDKYITIGVESTVSSETRYALAAKPDTFKVLAKRERDVEYHA
EHFDGRWVIRTNADDARNFKLVTAPTDATTRKQWTDWVAHDDSVYIENFELFDGFTAIEERSGGLERVRLQFNSPHMDVR
ALAGEPQYVKADEPAYSMGLSVNSEPDTPWLRYSYTSLTTPATTYELNTQTGERKLLKQQPVIGYDASKYVTERVWVTAR
DGVKVPVSLVYKKGFKKDGSAALFQYAYGSYGMSMDPVFNLPVISLLDRGVVYAIAHIRGGQEMGRQWYDDGKLLHKKNT
FNDFIDVTRGLVAQGYAAKDRVAASGGSAGGLLMGAVANMAPQDYRVMVAQVPFVDVVTTMLDASIPLTTNEYDEWGNPE
TKDYYDYMLSYSPYDNVRKQAYPALFVGTGLWDSQVQYWEPAKWVAKLRDDNTGTQPIVFRTNMEAGHGGKSGRFRRYRE
LAESYAFVLDQLGVK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=737, Percent_Identity=24.8303934871099, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI284172420, Length=537, Percent_Identity=25.512104283054, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI284172413, Length=537, Percent_Identity=25.512104283054, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI70778815, Length=537, Percent_Identity=25.512104283054, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI284172438, Length=537, Percent_Identity=25.512104283054, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI284172431, Length=537, Percent_Identity=25.512104283054, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI108860686, Length=342, Percent_Identity=27.7777777777778, Blast_Score=133, Evalue=6e-31,
Organism=Homo sapiens, GI108860692, Length=214, Percent_Identity=33.1775700934579, Blast_Score=128, Evalue=2e-29,
Organism=Escherichia coli, GI1788150, Length=684, Percent_Identity=46.0526315789474, Blast_Score=605, Evalue=1e-174,
Organism=Drosophila melanogaster, GI24583414, Length=744, Percent_Identity=23.9247311827957, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI221510989, Length=718, Percent_Identity=23.9554317548747, Blast_Score=172, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 83214; Mature: 83083

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPGNGLFHTQVLGWHCVHPTDPNLMKHALTLLIASLMTISPAFAAPPSPPGVAKHPHVV
CCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
KAPFGATRNDDYYWLRDDKREDKAMLAYLNAENAYADKVMAPLKPLEETLYTEIVGRIKQ
ECCCCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDASVPYRERGYWYYTRFETGKDYPIQARRKGSMDAPEEILLDVNQLAEGKGYFSVGDAK
CCCCCCCHHCCEEEEEEECCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCEEEECCCE
VSQDNRILAWVDDAVGRRQYTIRFKNLDTGERYPDTVEGVSPNVVWADDNKTLFYVENDP
ECCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCC
ETLLTVRVKKHVLGTSSKDDVLVYEEKDDSFYMSIGRTRDDKYITIGVESTVSSETRYAL
CEEEEEEEEHHHCCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEEEECCCCCCCCEEEE
AAKPDTFKVLAKRERDVEYHAEHFDGRWVIRTNADDARNFKLVTAPTDATTRKQWTDWVA
EECCCHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHC
HDDSVYIENFELFDGFTAIEERSGGLERVRLQFNSPHMDVRALAGEPQYVKADEPAYSMG
CCCCEEEEEEEECCCHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCEEECCCCCCEEC
LSVNSEPDTPWLRYSYTSLTTPATTYELNTQTGERKLLKQQPVIGYDASKYVTERVWVTA
EECCCCCCCCEEEEEECEECCCCEEEEECCCCCHHHHHHCCCCCCCCHHHHEEEEEEEEE
RDGVKVPVSLVYKKGFKKDGSAALFQYAYGSYGMSMDPVFNLPVISLLDRGVVYAIAHIR
CCCCCCCHHHEEHHCCCCCCCCEEEEEHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEHHC
GGQEMGRQWYDDGKLLHKKNTFNDFIDVTRGLVAQGYAAKDRVAASGGSAGGLLMGAVAN
CCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCHHHHHHHH
MAPQDYRVMVAQVPFVDVVTTMLDASIPLTTNEYDEWGNPETKDYYDYMLSYSPYDNVRK
CCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHEECCCHHHHHH
QAYPALFVGTGLWDSQVQYWEPAKWVAKLRDDNTGTQPIVFRTNMEAGHGGKSGRFRRYR
HHCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHH
ELAESYAFVLDQLGVK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPGNGLFHTQVLGWHCVHPTDPNLMKHALTLLIASLMTISPAFAAPPSPPGVAKHPHVV
CCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
KAPFGATRNDDYYWLRDDKREDKAMLAYLNAENAYADKVMAPLKPLEETLYTEIVGRIKQ
ECCCCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDASVPYRERGYWYYTRFETGKDYPIQARRKGSMDAPEEILLDVNQLAEGKGYFSVGDAK
CCCCCCCHHCCEEEEEEECCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCEEEECCCE
VSQDNRILAWVDDAVGRRQYTIRFKNLDTGERYPDTVEGVSPNVVWADDNKTLFYVENDP
ECCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCC
ETLLTVRVKKHVLGTSSKDDVLVYEEKDDSFYMSIGRTRDDKYITIGVESTVSSETRYAL
CEEEEEEEEHHHCCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEEEECCCCCCCCEEEE
AAKPDTFKVLAKRERDVEYHAEHFDGRWVIRTNADDARNFKLVTAPTDATTRKQWTDWVA
EECCCHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHC
HDDSVYIENFELFDGFTAIEERSGGLERVRLQFNSPHMDVRALAGEPQYVKADEPAYSMG
CCCCEEEEEEEECCCHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCEEECCCCCCEEC
LSVNSEPDTPWLRYSYTSLTTPATTYELNTQTGERKLLKQQPVIGYDASKYVTERVWVTA
EECCCCCCCCEEEEEECEECCCCEEEEECCCCCHHHHHHCCCCCCCCHHHHEEEEEEEEE
RDGVKVPVSLVYKKGFKKDGSAALFQYAYGSYGMSMDPVFNLPVISLLDRGVVYAIAHIR
CCCCCCCHHHEEHHCCCCCCCCEEEEEHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEHHC
GGQEMGRQWYDDGKLLHKKNTFNDFIDVTRGLVAQGYAAKDRVAASGGSAGGLLMGAVAN
CCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCHHHHHHHH
MAPQDYRVMVAQVPFVDVVTTMLDASIPLTTNEYDEWGNPETKDYYDYMLSYSPYDNVRK
CCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHEECCCHHHHHH
QAYPALFVGTGLWDSQVQYWEPAKWVAKLRDDNTGTQPIVFRTNMEAGHGGKSGRFRRYR
HHCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHH
ELAESYAFVLDQLGVK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]