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The map label for this gene is xerC [H]

Identifier: 84625422

GI number: 84625422

Start: 4257980

End: 4258897

Strand: Reverse

Name: xerC [H]

Synonym: XOO_3765

Alternate gene names: 84625422

Gene position: 4258897-4257980 (Counterclockwise)

Preceding gene: 84625423

Following gene: 84625421

Centisome position: 86.21

GC content: 64.16

Gene sequence:

>918_bases
GTGTCATCGGTCGACGAATTCCTGACCTATCTGCAGGTCGAGCGGCAGGTGTCGGCGCATACGTTGGATGCGTATCGACG
CGACCTTGCCGCGTTGGTTGCCTGGACAGGCGAGCGCAACGCGGAAGACGGCGCGCAGCAAACGGCCACGCCTGTCGACA
GTGCGCAGCTAGATAGCGCGCATTTGCGGCAGTTCGTCGCGGCCGAGCATCGACGTGGCCTTTCGCCCAAGAGTTTGCAG
CGCCGTTTGTCGGCGTGCCGCAGTTACTACGCGTGGTTGCTCAAGCATGGCCGCATCGCGGCCAGTCCGGCGGCGGCACT
GCGCGCACCCAAGGCGCAGCGCAAGTTGCCGCAAGTGCTGGACGCCGACGAAGCCGTGCGTCTGGTGGAAGTGCCAACCG
ATGCGCCACTGGGTCTGCGCGACCGCGCGCTGCTGGAATTGTTCTATTCCTCCGGGCTGCGTCTGAGCGAGCTATGCGCG
TTGCGCTGGCGCGATCTGGATCTGGACAGCGGCCTGGTGATGGTGCTCGGCAAGGGCAGCAAGCAGCGTCTCGTGCCGGT
GGGCTCGCACGCGATTGCCGCCTTGCGCCAATGGCGTCGCGACAGTGGTGCAAGCGCCGATGCGCACGTCTTCCCCGGGC
GTGCGGGCGGTGCGATTTCGCAACGCGCAGTGCAGATCCGCATCAAGCAACTGGCTGTGCGCCAGGGCATGTTCAAGGAC
GTGCATCCGCATATGCTGCGCCACAGTTTCGCCAGCCATATTCTGGAATCGTCCGGCGACCTGCGCGGCGTGCAGGAGTT
GCTGGGCCACTCGGACATCGCCACCACCCAGATCTATACACATCTGGATTTCCAGCATCTGGCCAAGGTCTATGACGCTG
CGCATCCGCGTGCCAGGCGCAAGAAAACCGTTGAATAA

Upstream 100 bases:

>100_bases
ACTGCAACTGCAACTGCAGGGCGCAACGTCTGCGTGCATGTTGCAGGGCTATCTGCACAAGCGGATGACGACATCCACGC
CAAGTATCGAGAGCGCTGAC

Downstream 100 bases:

>100_bases
GCGCTAAGCAGGAAGCGACAATTGGTAAGCAGGAAGCGTCGCAGCGCCGTGCGTGACCGAACATCGCAGACGCAGCAGGT
GATGCACGTTGCCAGCGCAA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSSVDEFLTYLQVERQVSAHTLDAYRRDLAALVAWTGERNAEDGAQQTATPVDSAQLDSAHLRQFVAAEHRRGLSPKSLQ
RRLSACRSYYAWLLKHGRIAASPAAALRAPKAQRKLPQVLDADEAVRLVEVPTDAPLGLRDRALLELFYSSGLRLSELCA
LRWRDLDLDSGLVMVLGKGSKQRLVPVGSHAIAALRQWRRDSGASADAHVFPGRAGGAISQRAVQIRIKQLAVRQGMFKD
VHPHMLRHSFASHILESSGDLRGVQELLGHSDIATTQIYTHLDFQHLAKVYDAAHPRARRKKTVE

Sequences:

>Translated_305_residues
MSSVDEFLTYLQVERQVSAHTLDAYRRDLAALVAWTGERNAEDGAQQTATPVDSAQLDSAHLRQFVAAEHRRGLSPKSLQ
RRLSACRSYYAWLLKHGRIAASPAAALRAPKAQRKLPQVLDADEAVRLVEVPTDAPLGLRDRALLELFYSSGLRLSELCA
LRWRDLDLDSGLVMVLGKGSKQRLVPVGSHAIAALRQWRRDSGASADAHVFPGRAGGAISQRAVQIRIKQLAVRQGMFKD
VHPHMLRHSFASHILESSGDLRGVQELLGHSDIATTQIYTHLDFQHLAKVYDAAHPRARRKKTVE
>Mature_304_residues
SSVDEFLTYLQVERQVSAHTLDAYRRDLAALVAWTGERNAEDGAQQTATPVDSAQLDSAHLRQFVAAEHRRGLSPKSLQR
RLSACRSYYAWLLKHGRIAASPAAALRAPKAQRKLPQVLDADEAVRLVEVPTDAPLGLRDRALLELFYSSGLRLSELCAL
RWRDLDLDSGLVMVLGKGSKQRLVPVGSHAIAALRQWRRDSGASADAHVFPGRAGGAISQRAVQIRIKQLAVRQGMFKDV
HPHMLRHSFASHILESSGDLRGVQELLGHSDIATTQIYTHLDFQHLAKVYDAAHPRARRKKTVE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=303, Percent_Identity=49.5049504950495, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1789261, Length=307, Percent_Identity=38.1107491856677, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1790767, Length=194, Percent_Identity=30.4123711340206, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33848; Mature: 33717

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVDEFLTYLQVERQVSAHTLDAYRRDLAALVAWTGERNAEDGAQQTATPVDSAQLDSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHCCHH
HLRQFVAAEHRRGLSPKSLQRRLSACRSYYAWLLKHGRIAASPAAALRAPKAQRKLPQVL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHH
DADEAVRLVEVPTDAPLGLRDRALLELFYSSGLRLSELCALRWRDLDLDSGLVMVLGKGS
CHHHCEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCC
KQRLVPVGSHAIAALRQWRRDSGASADAHVFPGRAGGAISQRAVQIRIKQLAVRQGMFKD
CCCEEECCHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VHPHMLRHSFASHILESSGDLRGVQELLGHSDIATTQIYTHLDFQHLAKVYDAAHPRARR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHH
KKTVE
CCCCC
>Mature Secondary Structure 
SSVDEFLTYLQVERQVSAHTLDAYRRDLAALVAWTGERNAEDGAQQTATPVDSAQLDSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHCCHH
HLRQFVAAEHRRGLSPKSLQRRLSACRSYYAWLLKHGRIAASPAAALRAPKAQRKLPQVL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHH
DADEAVRLVEVPTDAPLGLRDRALLELFYSSGLRLSELCALRWRDLDLDSGLVMVLGKGS
CHHHCEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCC
KQRLVPVGSHAIAALRQWRRDSGASADAHVFPGRAGGAISQRAVQIRIKQLAVRQGMFKD
CCCEEECCHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VHPHMLRHSFASHILESSGDLRGVQELLGHSDIATTQIYTHLDFQHLAKVYDAAHPRARR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHH
KKTVE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]