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The map label for this gene is prc [H]

Identifier: 84625384

GI number: 84625384

Start: 4212050

End: 4214233

Strand: Reverse

Name: prc [H]

Synonym: XOO_3727

Alternate gene names: 84625384

Gene position: 4214233-4212050 (Counterclockwise)

Preceding gene: 84625385

Following gene: 84625382

Centisome position: 85.3

GC content: 63.05

Gene sequence:

>2184_bases
ATGACCTACAACGTTCCTGTGTCCATGAAGGCCGGCCTGCTGGCGCTGGTGTTGACCACTCCGATGGCCTTGCTCGCGCG
CGCCGATACCGCGTTGCCTGCCGCCGCCACGCCCGACCAGGCGACGGCCACCAAACTCGTCTACGGCCTGCTCTCCGACA
GCCGCTATGCCTATCGGCCGCGCGTGCTGGATGAGGCGATGTCCAAGGACGTGTTCAAGCGCTATCTGGAAACGCTGGAC
GGCGGCAAGCAGTTCTTTACTCAGGCCGATATCGACAGCTTTGCTCCGCTGCAGGCCGGCGTTGGCGATGCACTGCGCGG
TGGCAATCTGGAGCCGGCCTTCCAGGTGTTCTCGCTCTACAAGAAGCGTGTCGATCAACGCGTCAAATACGCGCTCGATT
TGCTCAAGCAGGACTTCGATTTCAGCGGCAACGACAAGTTCGAGTACGACCGTAAGGACGTGCCATGGGCTGCAGACGAC
AAGCAGCTGGATGTGCTGTGGCGCCAGTCGGTCATGAACGACTGGTTGCGCCTGAAGCTGGCCGGCAAGAAGCCCGACGA
CATCCGCAAGACGCTGGATAAGCGCTACGTGGCGCTGGCCGATTCGGTCAAGCAGCTCAAGGGCGAAGACGTGTTCCAGT
TCTTCGTCAACGCTTACACCAATGCCGTCGACCCGCACACCGATTACTTCACGCCGCGTACTGCCGAGACGTTCAATCAG
CAGATGTCGCTGTCGCTGGAAGGCATCGGTGCGCAGCTGCAGAAGCAGGACGACATGGTGGTGATCCGCGAGGTGATCCC
GGGCGGTCCGGCGGCGGTGGATGGCACGCTCAAGCCGGGCGATCGCATCGTCGGCGTGGGCCAGACCAAGACTGGCGCGA
TCGAAGATGTGATCGGCTGGCGCATCGACGACGTGGTGGCCAAGATCCGCGGCAGCAAGGACACCCAGGTGCGCCTGGAA
TACATTCCGGCTGAATCGGGCATCGATGGCAAGCACCGCACCGTAACCCTGACCCGCCAGAAGGTACGTCTGGCCGAACA
GGCCGCAAAGGGCGAAACCATCACCTTGCCGGCCACGGGCACCGAGCCGCAGCGTCGCATCGGCATCATCAAGCTGCCGG
GCTTCTACCAGGATTTCGAAGGCCGTCGTCGCAATGCGACCGACTACGCCTCGGCGACCCGCGATGTCGCCAAGCTGCTG
GCCGGTTTCAAGACCGACAAGGTCGACGGCGTGGTGCTGGACTTGCGCAACAACGGCGGCGGCTCGCTGGATGAGGCAAT
CGAACTCACCGGCCTGTTCATCGAGCAGGGTCCGGTGGTGCAGGTGCGTGAATCCGGCGGGCGCGTCACCGTCAATGGCG
ACAGCGACCCCAAGGTCGCCTGGGACGGGCCGTTGGGGGTGTTGATCAACCGCGGCTCGGCATCGGCATCGGAAATCTTT
GCCGGTGCGATCCAGGATTACGGTCGTGGTCTGGTGATCGGCGAAACCAGCTTCGGTAAGGGCACCGTGCAGAACATCGT
CGACCTGGATCGCTGGCCGGCTGCCGAGGGGCAGCGCTACGGGCAGGTTAAGCTGACCATCGCGCAGTTCTTCCGCGTCA
GCGGTTCCAGCACCCAGCACAAGGGTGTCGTGCCGGATATCGTCTTCCCGGCCAGCGTAGATGCCACCGAATTCGGCGAG
AGCACCTACGACAACGCGCTGCCATGGACGCGCATCGCTGCCGCGCCGCACACCCAGTACGGCAACTTTGCGCCGCTGCT
GCCCAAGCTGCAGGCCCTGCACACCGCACGCATCGCCACCGACAAGGAATTCCAGTGGTGGGAAGAAGACGTCAAGCAGT
TTCGCGATGAAAAAGCCAAGAAGTACATTTCGTTGAATGAAGCCGAGCGCGTCGCCGAACGTCAGAAGCAGGATCAGCAG
CGCAAGGATCGCCAGCAGATCCGTAAGCAACTCGGGTTGCCGTTGGACCCGCTTGCCGAAGACAGCGACGACGGCTTGAC
CGGTAACGAGCGCGACATCGTCAAGGACACCGCACGCGAGAAGGCTGCCGAAAAGCGTCCGGATCCATTGCTGCATGAAT
CGGCTGCGATCCTGGCCGACGCGCTGGGCTTGCTGTCGCAGGACAAGCCGTTGTCGGCCCAGGTGCTGCCGAAGTCGACC
GCGCCGGGGCGTTGGGCGGATTGA

Upstream 100 bases:

>100_bases
TTCGGTCAGTGGATGACAACGCCAGCAACTTTCGGCACTGTCATGCTGTCTGATCCGTTTACCGCCTTCCTTTCATCGGC
CCTGTGCCGAGAGCCATTCG

Downstream 100 bases:

>100_bases
TGCCTGCGGTTCGTTGAAGCTGACAGTGTTTGAAAACGAAAATGCCACCGCACTGCGGTGGCATTTTCGTTGGCGGCATG
TCGTTGTGAGAGCGATATGC

Product: tail-specific protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 727; Mature: 726

Protein sequence:

>727_residues
MTYNVPVSMKAGLLALVLTTPMALLARADTALPAAATPDQATATKLVYGLLSDSRYAYRPRVLDEAMSKDVFKRYLETLD
GGKQFFTQADIDSFAPLQAGVGDALRGGNLEPAFQVFSLYKKRVDQRVKYALDLLKQDFDFSGNDKFEYDRKDVPWAADD
KQLDVLWRQSVMNDWLRLKLAGKKPDDIRKTLDKRYVALADSVKQLKGEDVFQFFVNAYTNAVDPHTDYFTPRTAETFNQ
QMSLSLEGIGAQLQKQDDMVVIREVIPGGPAAVDGTLKPGDRIVGVGQTKTGAIEDVIGWRIDDVVAKIRGSKDTQVRLE
YIPAESGIDGKHRTVTLTRQKVRLAEQAAKGETITLPATGTEPQRRIGIIKLPGFYQDFEGRRRNATDYASATRDVAKLL
AGFKTDKVDGVVLDLRNNGGGSLDEAIELTGLFIEQGPVVQVRESGGRVTVNGDSDPKVAWDGPLGVLINRGSASASEIF
AGAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPAAEGQRYGQVKLTIAQFFRVSGSSTQHKGVVPDIVFPASVDATEFGE
STYDNALPWTRIAAAPHTQYGNFAPLLPKLQALHTARIATDKEFQWWEEDVKQFRDEKAKKYISLNEAERVAERQKQDQQ
RKDRQQIRKQLGLPLDPLAEDSDDGLTGNERDIVKDTAREKAAEKRPDPLLHESAAILADALGLLSQDKPLSAQVLPKST
APGRWAD

Sequences:

>Translated_727_residues
MTYNVPVSMKAGLLALVLTTPMALLARADTALPAAATPDQATATKLVYGLLSDSRYAYRPRVLDEAMSKDVFKRYLETLD
GGKQFFTQADIDSFAPLQAGVGDALRGGNLEPAFQVFSLYKKRVDQRVKYALDLLKQDFDFSGNDKFEYDRKDVPWAADD
KQLDVLWRQSVMNDWLRLKLAGKKPDDIRKTLDKRYVALADSVKQLKGEDVFQFFVNAYTNAVDPHTDYFTPRTAETFNQ
QMSLSLEGIGAQLQKQDDMVVIREVIPGGPAAVDGTLKPGDRIVGVGQTKTGAIEDVIGWRIDDVVAKIRGSKDTQVRLE
YIPAESGIDGKHRTVTLTRQKVRLAEQAAKGETITLPATGTEPQRRIGIIKLPGFYQDFEGRRRNATDYASATRDVAKLL
AGFKTDKVDGVVLDLRNNGGGSLDEAIELTGLFIEQGPVVQVRESGGRVTVNGDSDPKVAWDGPLGVLINRGSASASEIF
AGAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPAAEGQRYGQVKLTIAQFFRVSGSSTQHKGVVPDIVFPASVDATEFGE
STYDNALPWTRIAAAPHTQYGNFAPLLPKLQALHTARIATDKEFQWWEEDVKQFRDEKAKKYISLNEAERVAERQKQDQQ
RKDRQQIRKQLGLPLDPLAEDSDDGLTGNERDIVKDTAREKAAEKRPDPLLHESAAILADALGLLSQDKPLSAQVLPKST
APGRWAD
>Mature_726_residues
TYNVPVSMKAGLLALVLTTPMALLARADTALPAAATPDQATATKLVYGLLSDSRYAYRPRVLDEAMSKDVFKRYLETLDG
GKQFFTQADIDSFAPLQAGVGDALRGGNLEPAFQVFSLYKKRVDQRVKYALDLLKQDFDFSGNDKFEYDRKDVPWAADDK
QLDVLWRQSVMNDWLRLKLAGKKPDDIRKTLDKRYVALADSVKQLKGEDVFQFFVNAYTNAVDPHTDYFTPRTAETFNQQ
MSLSLEGIGAQLQKQDDMVVIREVIPGGPAAVDGTLKPGDRIVGVGQTKTGAIEDVIGWRIDDVVAKIRGSKDTQVRLEY
IPAESGIDGKHRTVTLTRQKVRLAEQAAKGETITLPATGTEPQRRIGIIKLPGFYQDFEGRRRNATDYASATRDVAKLLA
GFKTDKVDGVVLDLRNNGGGSLDEAIELTGLFIEQGPVVQVRESGGRVTVNGDSDPKVAWDGPLGVLINRGSASASEIFA
GAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPAAEGQRYGQVKLTIAQFFRVSGSSTQHKGVVPDIVFPASVDATEFGES
TYDNALPWTRIAAAPHTQYGNFAPLLPKLQALHTARIATDKEFQWWEEDVKQFRDEKAKKYISLNEAERVAERQKQDQQR
KDRQQIRKQLGLPLDPLAEDSDDGLTGNERDIVKDTAREKAAEKRPDPLLHESAAILADALGLLSQDKPLSAQVLPKSTA
PGRWAD

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=716, Percent_Identity=41.6201117318436, Blast_Score=491, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 80169; Mature: 80038

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYNVPVSMKAGLLALVLTTPMALLARADTALPAAATPDQATATKLVYGLLSDSRYAYRP
CEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
RVLDEAMSKDVFKRYLETLDGGKQFFTQADIDSFAPLQAGVGDALRGGNLEPAFQVFSLY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHH
KKRVDQRVKYALDLLKQDFDFSGNDKFEYDRKDVPWAADDKQLDVLWRQSVMNDWLRLKL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEE
AGKKPDDIRKTLDKRYVALADSVKQLKGEDVFQFFVNAYTNAVDPHTDYFTPRTAETFNQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
QMSLSLEGIGAQLQKQDDMVVIREVIPGGPAAVDGTLKPGDRIVGVGQTKTGAIEDVIGW
HHEEEHHCCCCHHHCCCCEEEEEHHCCCCCCEECCCCCCCCEEEECCCCCCCCHHHHHCC
RIDDVVAKIRGSKDTQVRLEYIPAESGIDGKHRTVTLTRQKVRLAEQAAKGETITLPATG
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHCCCCEEEECCCC
TEPQRRIGIIKLPGFYQDFEGRRRNATDYASATRDVAKLLAGFKTDKVDGVVLDLRNNGG
CCHHHHEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
GSLDEAIELTGLFIEQGPVVQVRESGGRVTVNGDSDPKVAWDGPLGVLINRGSASASEIF
CCHHHHHHHHEEEECCCCEEEEECCCCEEEECCCCCCCEEECCCEEEEEECCCCCHHHHH
AGAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPAAEGQRYGQVKLTIAQFFRVSGSSTQH
HHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCCC
KGVVPDIVFPASVDATEFGESTYDNALPWTRIAAAPHTQYGNFAPLLPKLQALHTARIAT
CCCCCCEECCCCCCHHHCCCCCCCCCCCCHHEECCCCCCCCCCCHHHHHHHHHHHHHHCC
DKEFQWWEEDVKQFRDEKAKKYISLNEAERVAERQKQDQQRKDRQQIRKQLGLPLDPLAE
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DSDDGLTGNERDIVKDTAREKAAEKRPDPLLHESAAILADALGLLSQDKPLSAQVLPKST
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCC
APGRWAD
CCCCCCC
>Mature Secondary Structure 
TYNVPVSMKAGLLALVLTTPMALLARADTALPAAATPDQATATKLVYGLLSDSRYAYRP
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
RVLDEAMSKDVFKRYLETLDGGKQFFTQADIDSFAPLQAGVGDALRGGNLEPAFQVFSLY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHH
KKRVDQRVKYALDLLKQDFDFSGNDKFEYDRKDVPWAADDKQLDVLWRQSVMNDWLRLKL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEE
AGKKPDDIRKTLDKRYVALADSVKQLKGEDVFQFFVNAYTNAVDPHTDYFTPRTAETFNQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
QMSLSLEGIGAQLQKQDDMVVIREVIPGGPAAVDGTLKPGDRIVGVGQTKTGAIEDVIGW
HHEEEHHCCCCHHHCCCCEEEEEHHCCCCCCEECCCCCCCCEEEECCCCCCCCHHHHHCC
RIDDVVAKIRGSKDTQVRLEYIPAESGIDGKHRTVTLTRQKVRLAEQAAKGETITLPATG
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHCCCCEEEECCCC
TEPQRRIGIIKLPGFYQDFEGRRRNATDYASATRDVAKLLAGFKTDKVDGVVLDLRNNGG
CCHHHHEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
GSLDEAIELTGLFIEQGPVVQVRESGGRVTVNGDSDPKVAWDGPLGVLINRGSASASEIF
CCHHHHHHHHEEEECCCCEEEEECCCCEEEECCCCCCCEEECCCEEEEEECCCCCHHHHH
AGAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPAAEGQRYGQVKLTIAQFFRVSGSSTQH
HHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCCC
KGVVPDIVFPASVDATEFGESTYDNALPWTRIAAAPHTQYGNFAPLLPKLQALHTARIAT
CCCCCCEECCCCCCHHHCCCCCCCCCCCCHHEECCCCCCCCCCCHHHHHHHHHHHHHHCC
DKEFQWWEEDVKQFRDEKAKKYISLNEAERVAERQKQDQQRKDRQQIRKQLGLPLDPLAE
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DSDDGLTGNERDIVKDTAREKAAEKRPDPLLHESAAILADALGLLSQDKPLSAQVLPKST
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCC
APGRWAD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]