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The map label for this gene is 84625382

Identifier: 84625382

GI number: 84625382

Start: 4209676

End: 4210731

Strand: Reverse

Name: 84625382

Synonym: XOO_3725

Alternate gene names: NA

Gene position: 4210731-4209676 (Counterclockwise)

Preceding gene: 84625384

Following gene: 84625381

Centisome position: 85.23

GC content: 63.16

Gene sequence:

>1056_bases
ATGGCAACACCGTACGACTATCTCGTCTTTATCGGGCGTTTCGAGCCCTTTCATAACGGCCACGCCGCCGTCGCCCGCCA
CGCGCTGGGCAAGGCGAAGAAGCTCATCATGCTGATCGGCTCGGCCGACACGCCCCGCACCATTCGCAATCCGTGGACCG
TCGCCGAGCGCGCGGTGATGATCGAATCTGCGCTGCCGGACGAAACTGCGCGGCTGATCGTGCGCCCGTTACGCGACCAT
CTCTACAACGAAAGCCTGTGGATCGCCGAAGTGCAGCGTCAGGTTGCCGAGGCAGTGCAAGCCGATGGTGGCACGCTGGA
TGCGAACATCGGCCTGATCGGCATGGACAAAGATGCCAGCAGCTACTACTTGCGTGAGTTTCCGCAGTGGCCGCTGGAAG
ATGTGCAACACACTGCCACGCTGTCTGCCACCGAATTGCGCCGCTACCTGTTCGAAGCCGGCGATATCGGGTTCCACGGC
GGCTTGTTGATGTTGCGCGGCAATGTGCCGGCCCCGGTGTACGACATGCTGGAAGCGTTCCGGCGTAATTCGCCCAGCTA
CGCGCAGCTGGTGGCCGAATACCGTTTCATCGAGCAATACCGCGCGGCGTGGAAAGACGCGCCGTATCCGCCGACGTTCG
TCACTACCGACGCGGTCGTGGTGCACTCGGGCCATGTGCTGTTGGTGCGGCGTCGCGCCGAGCCGGGCAAGGGACTGTGG
GCATTGCCGGGCGGTTTTGTCGGCCAGGACGAAGGCCTGCTGGATTGCTGCTTGCGCGAGCTGCGCGAAGAAACCCGGCT
CAAGTTGCCGGTGCCGGTGCTCAAGGGCTCGTTGCGCGGCCGGCAGGTGTTCGACCACCCCGAGCGCAGCCAGCGCGGAC
GCACCATTACCCATGCGTTCCACTTCGAGTTTCCAGCCGGCGAATTGCCTGCGGTACGCGGTGGCGACGATGCCGATAAA
GCACGCTGGATTCCGATTGCCGAAGTCATGGCGATGGGTCCGCGCCTGTACGAAGACCACCTGCATATTCTTGAATTCTT
CCTGGGCCGTGGCTGA

Upstream 100 bases:

>100_bases
TGCATTGCGCAGGTGCTTGACGTCGCCGCGCATCGGCGTAGCATTTGCACCATGCTGGCGGAGAGACCGCCAGCTGACCA
CGCAACCGTGAGGGATTCTC

Downstream 100 bases:

>100_bases
GAGCGCAAACGGCCGCATGCTGCCAGCGAGACAACAGGGCCGCACGCGCTGTGACTGCTTGAACCGTGACCTCCCGCCGG
CGGACAGACCGCTGGTTCAT

Product: bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase

Products: NA

Alternate protein names: Nicotinamide-nucleotide adenylyltransferase; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; NMN adenylyltransferase; ADP compounds hydrolase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MATPYDYLVFIGRFEPFHNGHAAVARHALGKAKKLIMLIGSADTPRTIRNPWTVAERAVMIESALPDETARLIVRPLRDH
LYNESLWIAEVQRQVAEAVQADGGTLDANIGLIGMDKDASSYYLREFPQWPLEDVQHTATLSATELRRYLFEAGDIGFHG
GLLMLRGNVPAPVYDMLEAFRRNSPSYAQLVAEYRFIEQYRAAWKDAPYPPTFVTTDAVVVHSGHVLLVRRRAEPGKGLW
ALPGGFVGQDEGLLDCCLRELREETRLKLPVPVLKGSLRGRQVFDHPERSQRGRTITHAFHFEFPAGELPAVRGGDDADK
ARWIPIAEVMAMGPRLYEDHLHILEFFLGRG

Sequences:

>Translated_351_residues
MATPYDYLVFIGRFEPFHNGHAAVARHALGKAKKLIMLIGSADTPRTIRNPWTVAERAVMIESALPDETARLIVRPLRDH
LYNESLWIAEVQRQVAEAVQADGGTLDANIGLIGMDKDASSYYLREFPQWPLEDVQHTATLSATELRRYLFEAGDIGFHG
GLLMLRGNVPAPVYDMLEAFRRNSPSYAQLVAEYRFIEQYRAAWKDAPYPPTFVTTDAVVVHSGHVLLVRRRAEPGKGLW
ALPGGFVGQDEGLLDCCLRELREETRLKLPVPVLKGSLRGRQVFDHPERSQRGRTITHAFHFEFPAGELPAVRGGDDADK
ARWIPIAEVMAMGPRLYEDHLHILEFFLGRG
>Mature_350_residues
ATPYDYLVFIGRFEPFHNGHAAVARHALGKAKKLIMLIGSADTPRTIRNPWTVAERAVMIESALPDETARLIVRPLRDHL
YNESLWIAEVQRQVAEAVQADGGTLDANIGLIGMDKDASSYYLREFPQWPLEDVQHTATLSATELRRYLFEAGDIGFHGG
LLMLRGNVPAPVYDMLEAFRRNSPSYAQLVAEYRFIEQYRAAWKDAPYPPTFVTTDAVVVHSGHVLLVRRRAEPGKGLWA
LPGGFVGQDEGLLDCCLRELREETRLKLPVPVLKGSLRGRQVFDHPERSQRGRTITHAFHFEFPAGELPAVRGGDDADKA
RWIPIAEVMAMGPRLYEDHLHILEFFLGRG

Specific function: The Nudix hydrolase domain is active on ADP-ribose, (2')-phospho-ADP-ribose, IDP-ribose and NADPH [H]

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00293 NUDIX [H]

EC number: =2.7.7.1 [H]

Molecular weight: Translated: 39504; Mature: 39373

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPYDYLVFIGRFEPFHNGHAAVARHALGKAKKLIMLIGSADTPRTIRNPWTVAERAVM
CCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCEEEEEEECCCCCCHHCCCHHHHHHHHH
IESALPDETARLIVRPLRDHLYNESLWIAEVQRQVAEAVQADGGTLDANIGLIGMDKDAS
HHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCC
SYYLREFPQWPLEDVQHTATLSATELRRYLFEAGDIGFHGGLLMLRGNVPAPVYDMLEAF
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHH
RRNSPSYAQLVAEYRFIEQYRAAWKDAPYPPTFVTTDAVVVHSGHVLLVRRRAEPGKGLW
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCEEEEEECCCCCCCEE
ALPGGFVGQDEGLLDCCLRELREETRLKLPVPVLKGSLRGRQVFDHPERSQRGRTITHAF
ECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHCCCEEEEEE
HFEFPAGELPAVRGGDDADKARWIPIAEVMAMGPRLYEDHLHILEFFLGRG
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATPYDYLVFIGRFEPFHNGHAAVARHALGKAKKLIMLIGSADTPRTIRNPWTVAERAVM
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCEEEEEEECCCCCCHHCCCHHHHHHHHH
IESALPDETARLIVRPLRDHLYNESLWIAEVQRQVAEAVQADGGTLDANIGLIGMDKDAS
HHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCC
SYYLREFPQWPLEDVQHTATLSATELRRYLFEAGDIGFHGGLLMLRGNVPAPVYDMLEAF
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHH
RRNSPSYAQLVAEYRFIEQYRAAWKDAPYPPTFVTTDAVVVHSGHVLLVRRRAEPGKGLW
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCEEEEEECCCCCCCEE
ALPGGFVGQDEGLLDCCLRELREETRLKLPVPVLKGSLRGRQVFDHPERSQRGRTITHAF
ECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHCCCEEEEEE
HFEFPAGELPAVRGGDDADKARWIPIAEVMAMGPRLYEDHLHILEFFLGRG
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10050763 [H]