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The map label for this gene is fkpB [C]

Identifier: 84489146

GI number: 84489146

Start: 385116

End: 385868

Strand: Direct

Name: fkpB [C]

Synonym: Msp_0325

Alternate gene names: 84489146

Gene position: 385116-385868 (Clockwise)

Preceding gene: 84489145

Following gene: 84489148

Centisome position: 21.79

GC content: 29.35

Gene sequence:

>753_bases
ATGCCAATAGATGATAAAGATTTTGTAAAATTAAATTACACTGGAAAAGTTAAAGAAACTGGAGACGTATTTGATACAAC
ATATGAAGATGTTGCTGAAGAAGCAGGTATCAAAAACGAAAACAAAGATTATCACCCAATGATTCTTGCAGTAGGATCTA
CTCAATTACTCTCAAAATTACATGATGAAATTAAAAAAATGGATGTAGGAGAAAAACAAACAGTAGAAATCCCATGTGAA
GAAGCATTTGGTAAAAGAGATCCAAGTTTAATTCAATTAATTCCAATGAAAGAATTCAAAAAACAAAACATTAAACCATT
TGTAGGCATGCCCTTATCATTAGATGGACAACATGGAATTGTAAGAACTGTAGATGGTGGAAGAGTAAGAGTAGATTTCA
ACCATGAATTAGCTGGTAAAGATATAATTTATGAAATTGAAATTGTAGATACAATTGATGATAATGTTGAAAAAATTAAA
GGATTAATAGAAGTATACTATGGAAATCCTAACATTGACTTAGAAAAAACAGAAATTCTTATTGAAGATGGTGTAGCTAA
AATCACATTAGATAAATTAGCAGGATTCGAACAAAGATCTGCACAAGAAATAACATTATCTAAATTCAGAGTAGCAAGAG
AAACATATGAAAACATCGATGAAATTGAAAAAGTTCAATTTATTGATGAATATGAAAAACCTGAACCAGAAGAAGAATCT
GAAGATGCTCCAGAAGTATTAGATGAAGAATAA

Upstream 100 bases:

>100_bases
ATCCACAAAAAATTAAAATTTTAGGATATAAAAATAAAGAAGTTCTAAATAAATTTAAAGTTAATTTGGAAAATAATTTA
AAAGGAGAAAATGGAAAAGT

Downstream 100 bases:

>100_bases
GTAATTAATTGGGATTTATTATCCCTAACTTTTTTTCATACTATTTTTGATGTAACTTCAATTACTTTTTCACATTGAAT
TAAATCTTCAATAGTATTTA

Product: peptidyl-prolyl cis-trans isomerase 2

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MPIDDKDFVKLNYTGKVKETGDVFDTTYEDVAEEAGIKNENKDYHPMILAVGSTQLLSKLHDEIKKMDVGEKQTVEIPCE
EAFGKRDPSLIQLIPMKEFKKQNIKPFVGMPLSLDGQHGIVRTVDGGRVRVDFNHELAGKDIIYEIEIVDTIDDNVEKIK
GLIEVYYGNPNIDLEKTEILIEDGVAKITLDKLAGFEQRSAQEITLSKFRVARETYENIDEIEKVQFIDEYEKPEPEEES
EDAPEVLDEE

Sequences:

>Translated_250_residues
MPIDDKDFVKLNYTGKVKETGDVFDTTYEDVAEEAGIKNENKDYHPMILAVGSTQLLSKLHDEIKKMDVGEKQTVEIPCE
EAFGKRDPSLIQLIPMKEFKKQNIKPFVGMPLSLDGQHGIVRTVDGGRVRVDFNHELAGKDIIYEIEIVDTIDDNVEKIK
GLIEVYYGNPNIDLEKTEILIEDGVAKITLDKLAGFEQRSAQEITLSKFRVARETYENIDEIEKVQFIDEYEKPEPEEES
EDAPEVLDEE
>Mature_249_residues
PIDDKDFVKLNYTGKVKETGDVFDTTYEDVAEEAGIKNENKDYHPMILAVGSTQLLSKLHDEIKKMDVGEKQTVEIPCEE
AFGKRDPSLIQLIPMKEFKKQNIKPFVGMPLSLDGQHGIVRTVDGGRVRVDFNHELAGKDIIYEIEIVDTIDDNVEKIKG
LIEVYYGNPNIDLEKTEILIEDGVAKITLDKLAGFEQRSAQEITLSKFRVARETYENIDEIEKVQFIDEYEKPEPEEESE
DAPEVLDEE

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786211, Length=140, Percent_Identity=29.2857142857143, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 28496; Mature: 28365

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDDKDFVKLNYTGKVKETGDVFDTTYEDVAEEAGIKNENKDYHPMILAVGSTQLLSKL
CCCCCCCEEEEEECCCCCCCCCHHHCHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHH
HDEIKKMDVGEKQTVEIPCEEAFGKRDPSLIQLIPMKEFKKQNIKPFVGMPLSLDGQHGI
HHHHHHCCCCCCEEEECCHHHHCCCCCCCEEEEECHHHHHHCCCCCEECCCEEECCCCCE
VRTVDGGRVRVDFNHELAGKDIIYEIEIVDTIDDNVEKIKGLIEVYYGNPNIDLEKTEIL
EEEECCCEEEEEECCCCCCCCEEEEEEEEECCCHHHHHHHHEEEEEECCCCCCCHHHEEE
IEDGVAKITLDKLAGFEQRSAQEITLSKFRVARETYENIDEIEKVQFIDEYEKPEPEEES
EECCCEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EDAPEVLDEE
CCCCHHCCCC
>Mature Secondary Structure 
PIDDKDFVKLNYTGKVKETGDVFDTTYEDVAEEAGIKNENKDYHPMILAVGSTQLLSKL
CCCCCCEEEEEECCCCCCCCCHHHCHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHH
HDEIKKMDVGEKQTVEIPCEEAFGKRDPSLIQLIPMKEFKKQNIKPFVGMPLSLDGQHGI
HHHHHHCCCCCCEEEECCHHHHCCCCCCCEEEEECHHHHHHCCCCCEECCCEEECCCCCE
VRTVDGGRVRVDFNHELAGKDIIYEIEIVDTIDDNVEKIKGLIEVYYGNPNIDLEKTEIL
EEEECCCEEEEEECCCCCCCCEEEEEEEEECCCHHHHHHHHEEEEEECCCCCCCHHHEEE
IEDGVAKITLDKLAGFEQRSAQEITLSKFRVARETYENIDEIEKVQFIDEYEKPEPEEES
EECCCEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EDAPEVLDEE
CCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]