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The map label for this gene is 84489002

Identifier: 84489002

GI number: 84489002

Start: 216085

End: 217587

Strand: Direct

Name: 84489002

Synonym: Msp_0174

Alternate gene names: NA

Gene position: 216085-217587 (Clockwise)

Preceding gene: 84489001

Following gene: 84489006

Centisome position: 12.23

GC content: 30.74

Gene sequence:

>1503_bases
ATGACAAAGATAGGAATTTTAGAAGTTGAAGGTGTTTTAACATTATATGAACACTTTGGTTATTTACCTACAGATGTAGT
TAAATCTAATGGTAGATTGGAAAATGGAAAAAAAGCTCATGAAGAATTAGATGGTATAATAATACCTGGAGGTACAATTC
TTGAATCAGAATCTATGACTGGTGAGGTTGAAGAAGAAATTAATCTTATAAATGATGATGATGGGTTTATTTTAGGTATG
TGTGCAGGATTTCAGGTACTTGGAAAACATACAAATGTTGGAAGAAACTCTCCAGTACCAATAATAAGAAAGGGTATGGG
TCTTTTAGATGTTACTTTTGAACCATTTATAAATACAAATAAGGTAAATGCAGATATTGTTGATGATAACACACTCTTTA
CAAAAAACTTAAAGGACACAACAGTAAGTGGTTTTCATTGTCATACATATGGTAGGATAGAATCAAATGATAAGAATGTT
ATCTACTCTAATATTCAAAGATCAAACTATAAATATAAACCAGAAAGGGTATTATCTGGTGTTTCAAATAAAAAGGGAAA
TATATTAGGAACAACAGTGCACTGTTTACTTGATAATAATCCTCAAATAGTAAACAACATACTAGAATATCTTGATGCTA
CAAATGAATATGAAGACATTAAACAAAGAAATAAAAAACTTCAAAGTAAGGTATTTTCTGAAATTGGAGTCGATACAAAC
AACATGGCACCACTAAGAGAAAAACATCCTGAAGTTCCACCAATGATAATGTTAATGGGAACAGGTTCTGAATCTGGAAA
AACATTTCTTGCTAGTGGAATTGTAGGAGCACTAAGAGAAAAGGGAATACATACGTATGTAATTAAAACAGGTCCTGATA
TAAGAGATTTATCACCATCTCTTTATGTAAATAAGGAAAAATTGGAGGATTATGCATCGATACAAATAAGTAATATTGGA
TGGACTCCACTTGAAAAAATAATAGAACAAGTAAAGAATAAGGGCTATGATTTAGTACTGGTTGAAGGAGTAATGAGTGC
AGCAACAGGACTACTTAATAAAAAAACACCATATTCAACTGCAGAAATTGCATATGCAGGTAATATTCCTGTTATAATGG
TATCTAGTGTAAGTAAGGGTGGTATTGAAACAGCAGCTATTGATATTGAAGCACATATTAATCTATTAAATAAGATGGAT
GTTAAAACAGCTGGTGTTATTTTAAATAAAACCTATGATGAAGGTATTGTGGAACATGTATCTGAATTCTTATCTAATAA
ATCTGGAATACCAGAGGATAATATTTGGAGTATTGGTAAGGCCAAAGTAGAGAATAAAGGACAGGTTCCAGAGGATTATC
TTCAATTGGAAACATTTACAAAAGCAGCAATGGATGTTGTTAAAGAATATGTGGATGTTACAAAAATAATGGATTTAGCT
AAAGTACCAGAATTTAGAGGATACTTATCCTATGAGGAAATTTGTGATTTATATAAAAAATAG

Upstream 100 bases:

>100_bases
TATAGATATTATTGAAATTCTATTATAGAATTCTAATAAATTATTTTTATATAGTCAAACAATAGATTTAATTATAGAAT
GAAATTTTTAATGTGATTGT

Downstream 100 bases:

>100_bases
TTTCATAAAAAAAAGGAGTATGGAGAATTTAATTGTTATTTTTAAATTCTTTGTATGCTTCTATTATTTCATCACCACTA
ATAAATACGTGATTATTTTT

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MTKIGILEVEGVLTLYEHFGYLPTDVVKSNGRLENGKKAHEELDGIIIPGGTILESESMTGEVEEEINLINDDDGFILGM
CAGFQVLGKHTNVGRNSPVPIIRKGMGLLDVTFEPFINTNKVNADIVDDNTLFTKNLKDTTVSGFHCHTYGRIESNDKNV
IYSNIQRSNYKYKPERVLSGVSNKKGNILGTTVHCLLDNNPQIVNNILEYLDATNEYEDIKQRNKKLQSKVFSEIGVDTN
NMAPLREKHPEVPPMIMLMGTGSESGKTFLASGIVGALREKGIHTYVIKTGPDIRDLSPSLYVNKEKLEDYASIQISNIG
WTPLEKIIEQVKNKGYDLVLVEGVMSAATGLLNKKTPYSTAEIAYAGNIPVIMVSSVSKGGIETAAIDIEAHINLLNKMD
VKTAGVILNKTYDEGIVEHVSEFLSNKSGIPEDNIWSIGKAKVENKGQVPEDYLQLETFTKAAMDVVKEYVDVTKIMDLA
KVPEFRGYLSYEEICDLYKK

Sequences:

>Translated_500_residues
MTKIGILEVEGVLTLYEHFGYLPTDVVKSNGRLENGKKAHEELDGIIIPGGTILESESMTGEVEEEINLINDDDGFILGM
CAGFQVLGKHTNVGRNSPVPIIRKGMGLLDVTFEPFINTNKVNADIVDDNTLFTKNLKDTTVSGFHCHTYGRIESNDKNV
IYSNIQRSNYKYKPERVLSGVSNKKGNILGTTVHCLLDNNPQIVNNILEYLDATNEYEDIKQRNKKLQSKVFSEIGVDTN
NMAPLREKHPEVPPMIMLMGTGSESGKTFLASGIVGALREKGIHTYVIKTGPDIRDLSPSLYVNKEKLEDYASIQISNIG
WTPLEKIIEQVKNKGYDLVLVEGVMSAATGLLNKKTPYSTAEIAYAGNIPVIMVSSVSKGGIETAAIDIEAHINLLNKMD
VKTAGVILNKTYDEGIVEHVSEFLSNKSGIPEDNIWSIGKAKVENKGQVPEDYLQLETFTKAAMDVVKEYVDVTKIMDLA
KVPEFRGYLSYEEICDLYKK
>Mature_499_residues
TKIGILEVEGVLTLYEHFGYLPTDVVKSNGRLENGKKAHEELDGIIIPGGTILESESMTGEVEEEINLINDDDGFILGMC
AGFQVLGKHTNVGRNSPVPIIRKGMGLLDVTFEPFINTNKVNADIVDDNTLFTKNLKDTTVSGFHCHTYGRIESNDKNVI
YSNIQRSNYKYKPERVLSGVSNKKGNILGTTVHCLLDNNPQIVNNILEYLDATNEYEDIKQRNKKLQSKVFSEIGVDTNN
MAPLREKHPEVPPMIMLMGTGSESGKTFLASGIVGALREKGIHTYVIKTGPDIRDLSPSLYVNKEKLEDYASIQISNIGW
TPLEKIIEQVKNKGYDLVLVEGVMSAATGLLNKKTPYSTAEIAYAGNIPVIMVSSVSKGGIETAAIDIEAHINLLNKMDV
KTAGVILNKTYDEGIVEHVSEFLSNKSGIPEDNIWSIGKAKVENKGQVPEDYLQLETFTKAAMDVVKEYVDVTKIMDLAK
VPEFRGYLSYEEICDLYKK

Specific function: Unknown

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017926
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 55349; Mature: 55218

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIGILEVEGVLTLYEHFGYLPTDVVKSNGRLENGKKAHEELDGIIIPGGTILESESMT
CCCEEEEEHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHCCCEEECCCCEEECCCCC
GEVEEEINLINDDDGFILGMCAGFQVLGKHTNVGRNSPVPIIRKGMGLLDVTFEPFINTN
CCCHHHCCEECCCCCEEEEEHHCHHHHCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCC
KVNADIVDDNTLFTKNLKDTTVSGFHCHTYGRIESNDKNVIYSNIQRSNYKYKPERVLSG
CCEEEEECCCCEEECCCCCCCCCCEEEEEECCEECCCCCEEEECCCCCCCCCCHHHHHCC
VSNKKGNILGTTVHCLLDNNPQIVNNILEYLDATNEYEDIKQRNKKLQSKVFSEIGVDTN
CCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
NMAPLREKHPEVPPMIMLMGTGSESGKTFLASGIVGALREKGIHTYVIKTGPDIRDLSPS
CCCCHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCC
LYVNKEKLEDYASIQISNIGWTPLEKIIEQVKNKGYDLVLVEGVMSAATGLLNKKTPYST
CEEEHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCCC
AEIAYAGNIPVIMVSSVSKGGIETAAIDIEAHINLLNKMDVKTAGVILNKTYDEGIVEHV
EEEEEECCCCEEEEECCCCCCCEEEEEEHHHHHHHHHHCCCHHHCEEEECCHHHHHHHHH
SEFLSNKSGIPEDNIWSIGKAKVENKGQVPEDYLQLETFTKAAMDVVKEYVDVTKIMDLA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVPEFRGYLSYEEICDLYKK
HCCHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
TKIGILEVEGVLTLYEHFGYLPTDVVKSNGRLENGKKAHEELDGIIIPGGTILESESMT
CCEEEEEHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHCCCEEECCCCEEECCCCC
GEVEEEINLINDDDGFILGMCAGFQVLGKHTNVGRNSPVPIIRKGMGLLDVTFEPFINTN
CCCHHHCCEECCCCCEEEEEHHCHHHHCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCC
KVNADIVDDNTLFTKNLKDTTVSGFHCHTYGRIESNDKNVIYSNIQRSNYKYKPERVLSG
CCEEEEECCCCEEECCCCCCCCCCEEEEEECCEECCCCCEEEECCCCCCCCCCHHHHHCC
VSNKKGNILGTTVHCLLDNNPQIVNNILEYLDATNEYEDIKQRNKKLQSKVFSEIGVDTN
CCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
NMAPLREKHPEVPPMIMLMGTGSESGKTFLASGIVGALREKGIHTYVIKTGPDIRDLSPS
CCCCHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCC
LYVNKEKLEDYASIQISNIGWTPLEKIIEQVKNKGYDLVLVEGVMSAATGLLNKKTPYST
CEEEHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCCC
AEIAYAGNIPVIMVSSVSKGGIETAAIDIEAHINLLNKMDVKTAGVILNKTYDEGIVEHV
EEEEEECCCCEEEEECCCCCCCEEEEEEHHHHHHHHHHCCCHHHCEEEECCHHHHHHHHH
SEFLSNKSGIPEDNIWSIGKAKVENKGQVPEDYLQLETFTKAAMDVVKEYVDVTKIMDLA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVPEFRGYLSYEEICDLYKK
HCCHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]