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The map label for this gene is cbiA

Identifier: 84488991

GI number: 84488991

Start: 202830

End: 204191

Strand: Direct

Name: cbiA

Synonym: Msp_0162

Alternate gene names: 84488991

Gene position: 202830-204191 (Clockwise)

Preceding gene: 84488989

Following gene: 84488992

Centisome position: 11.48

GC content: 32.45

Gene sequence:

>1362_bases
ATGAAAAGAGTAGTATTGACAGGAACAGGAAGTGGTGTTGGTAAGACAACCATAGCCACTGGTATTATGAAGGCATTATC
TGATGAACATAAAATACAACCATTTAAGGTAGGTCCAGATTATATTGATCCTTCATATCATAATTGTGCAACGGGAGTTT
CTTCTCGTAATTTAGATTCATTTTTCATGTCTGATGGACAGATAAGACAATCCTTCAAAAATGGAATGACATCATCCCAT
GCAGATTATGGAATTATTGAGGGAGTTAGAGGGTTATATGAGGGAATAAGTCCTACTAATGATATAGGAAGTACTTCTTC
AATTGCAAAAGCACTTAATTCTCCAGTAATATTGATAATAAATAGTCGTAGTCTTGTTAGAAGTGCAGCAGCAATGACTC
TTGGATTTAAGGCACTAGATTCACGGATAGATATTGAAGGAGTAATCTTAAACAATGTTAAAAGTCAAAAACATTACTTA
AAAACAAAGGAAGCAGTTGAAAAACTAGCAAATACTCGTGTTCTTGGAGGTATTGAGAGGGATAATTCCATATCAATGGA
ACAAAGACATCTTGGACTGATACCTGCCGTGGAACAAGAACGTATATCTGGACTTGTAGAGAAATGGGGAGAATTAATAA
GGGAAAATATTGATCTTGATGCATTAATGGAGATAATGGATAATTCTAATCCAATAATTAATGAATATGAACCAATATGG
TCACCTAATAAAACAAAACATAAAACAAGAATAGCTGTTCCATTTGATGAAGCCTTTAACTTCTATTATAAGGAAAATCT
TGAAGCACTAGAATATAACAATGCTAAAATAGAATACTTCAGTCCAATACATGATGAACAATTACCATCTGTTGATGCAT
TGTATATTGGTGGAGGATATCCTGAAATATTTAAGAAGGAATTATCAAAAAATACTACAATGCTTGAATCAATAAAAGAA
TTTTCACAAGATAATCATCCAATATATGCTGAATGTGGAGGACTCATGTATCTGTGTAAAACAATAGATTCTCTACCTAT
GGTTGATGTATTTCCTTATCATTCAATGTTAACAAAAAGGGTACAGGGACTAAGCTATACAATAGCACATGTTCAAAGGG
ATAATCCAATACTAAAGAAAAATACAACATATCATGGACATGAATTCCATTATTCTAAGGTAGAATACACAGGCTCAAAT
TCAAATGACTTTGCATTTAGTATGAGACGTGGTGTTGGAATAACAGGTAAATATGATGGATTACTAAAAAATAACACATT
GGCAAGTTATATTCACACCCATACTGCATGTTTACCAGATTTTGGATATAATTTTACACAGTCTGCATATGAAAATAAAT
AA

Upstream 100 bases:

>100_bases
AATCTATATCTTATTAATTTAAAATATAATTATAATAAGTATTAAAATAAAATGGATATGATATTTTTTTTTAGTTTTAT
TTCTCAAGTAGGTTATTTAT

Downstream 100 bases:

>100_bases
AATAATATAAAAAAAATAAGTATAGAATTTATGTAATAATAAGAGTGAAATCATGGTAGTAAAAATAGGAATTGTAAAAG
TTGGTAACATAGGAACATCT

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKRVVLTGTGSGVGKTTIATGIMKALSDEHKIQPFKVGPDYIDPSYHNCATGVSSRNLDSFFMSDGQIRQSFKNGMTSSH
ADYGIIEGVRGLYEGISPTNDIGSTSSIAKALNSPVILIINSRSLVRSAAAMTLGFKALDSRIDIEGVILNNVKSQKHYL
KTKEAVEKLANTRVLGGIERDNSISMEQRHLGLIPAVEQERISGLVEKWGELIRENIDLDALMEIMDNSNPIINEYEPIW
SPNKTKHKTRIAVPFDEAFNFYYKENLEALEYNNAKIEYFSPIHDEQLPSVDALYIGGGYPEIFKKELSKNTTMLESIKE
FSQDNHPIYAECGGLMYLCKTIDSLPMVDVFPYHSMLTKRVQGLSYTIAHVQRDNPILKKNTTYHGHEFHYSKVEYTGSN
SNDFAFSMRRGVGITGKYDGLLKNNTLASYIHTHTACLPDFGYNFTQSAYENK

Sequences:

>Translated_453_residues
MKRVVLTGTGSGVGKTTIATGIMKALSDEHKIQPFKVGPDYIDPSYHNCATGVSSRNLDSFFMSDGQIRQSFKNGMTSSH
ADYGIIEGVRGLYEGISPTNDIGSTSSIAKALNSPVILIINSRSLVRSAAAMTLGFKALDSRIDIEGVILNNVKSQKHYL
KTKEAVEKLANTRVLGGIERDNSISMEQRHLGLIPAVEQERISGLVEKWGELIRENIDLDALMEIMDNSNPIINEYEPIW
SPNKTKHKTRIAVPFDEAFNFYYKENLEALEYNNAKIEYFSPIHDEQLPSVDALYIGGGYPEIFKKELSKNTTMLESIKE
FSQDNHPIYAECGGLMYLCKTIDSLPMVDVFPYHSMLTKRVQGLSYTIAHVQRDNPILKKNTTYHGHEFHYSKVEYTGSN
SNDFAFSMRRGVGITGKYDGLLKNNTLASYIHTHTACLPDFGYNFTQSAYENK
>Mature_453_residues
MKRVVLTGTGSGVGKTTIATGIMKALSDEHKIQPFKVGPDYIDPSYHNCATGVSSRNLDSFFMSDGQIRQSFKNGMTSSH
ADYGIIEGVRGLYEGISPTNDIGSTSSIAKALNSPVILIINSRSLVRSAAAMTLGFKALDSRIDIEGVILNNVKSQKHYL
KTKEAVEKLANTRVLGGIERDNSISMEQRHLGLIPAVEQERISGLVEKWGELIRENIDLDALMEIMDNSNPIINEYEPIW
SPNKTKHKTRIAVPFDEAFNFYYKENLEALEYNNAKIEYFSPIHDEQLPSVDALYIGGGYPEIFKKELSKNTTMLESIKE
FSQDNHPIYAECGGLMYLCKTIDSLPMVDVFPYHSMLTKRVQGLSYTIAHVQRDNPILKKNTTYHGHEFHYSKVEYTGSN
SNDFAFSMRRGVGITGKYDGLLKNNTLASYIHTHTACLPDFGYNFTQSAYENK

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBB_METST (Q2NHQ3)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447223.1
- ProteinModelPortal:   Q2NHQ3
- STRING:   Q2NHQ3
- GeneID:   3856036
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0162
- NMPDR:   fig|339860.6.peg.160
- eggNOG:   arNOG04865
- HOGENOM:   HBG634910
- OMA:   MRHLGLV
- ProtClustDB:   PRK01077
- BioCyc:   MSTA339860:MSP_0162-MONOMER
- HAMAP:   MF_00027
- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698
- TIGRFAMs:   TIGR00379

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3

EC number: NA

Molecular weight: Translated: 50721; Mature: 50721

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS51274 GATASE_COBBQ

Important sites: ACT_SITE 332-332 ACT_SITE 432-432

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVVLTGTGSGVGKTTIATGIMKALSDEHKIQPFKVGPDYIDPSYHNCATGVSSRNLDS
CCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHCCCCCCCCHH
FFMSDGQIRQSFKNGMTSSHADYGIIEGVRGLYEGISPTNDIGSTSSIAKALNSPVILII
HHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEE
NSRSLVRSAAAMTLGFKALDSRIDIEGVILNNVKSQKHYLKTKEAVEKLANTRVLGGIER
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHCCCCCC
DNSISMEQRHLGLIPAVEQERISGLVEKWGELIRENIDLDALMEIMDNSNPIINEYEPIW
CCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
SPNKTKHKTRIAVPFDEAFNFYYKENLEALEYNNAKIEYFSPIHDEQLPSVDALYIGGGY
CCCCCCCCEEEEEEHHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCCCCCEEEECCCC
PEIFKKELSKNTTMLESIKEFSQDNHPIYAECGGLMYLCKTIDSLPMVDVFPYHSMLTKR
HHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCEEECCHHHHHHHH
VQGLSYTIAHVQRDNPILKKNTTYHGHEFHYSKVEYTGSNSNDFAFSMRRGVGITGKYDG
HHCCEEEEEEEECCCCEEECCCCCCCCEEEEEEEEEECCCCCCEEEEHHCCCCCCCCCCC
LLKNNTLASYIHTHTACLPDFGYNFTQSAYENK
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MKRVVLTGTGSGVGKTTIATGIMKALSDEHKIQPFKVGPDYIDPSYHNCATGVSSRNLDS
CCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHCCCCCCCCHH
FFMSDGQIRQSFKNGMTSSHADYGIIEGVRGLYEGISPTNDIGSTSSIAKALNSPVILII
HHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEE
NSRSLVRSAAAMTLGFKALDSRIDIEGVILNNVKSQKHYLKTKEAVEKLANTRVLGGIER
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHCCCCCC
DNSISMEQRHLGLIPAVEQERISGLVEKWGELIRENIDLDALMEIMDNSNPIINEYEPIW
CCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
SPNKTKHKTRIAVPFDEAFNFYYKENLEALEYNNAKIEYFSPIHDEQLPSVDALYIGGGY
CCCCCCCCEEEEEEHHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCCCCCEEEECCCC
PEIFKKELSKNTTMLESIKEFSQDNHPIYAECGGLMYLCKTIDSLPMVDVFPYHSMLTKR
HHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCEEECCHHHHHHHH
VQGLSYTIAHVQRDNPILKKNTTYHGHEFHYSKVEYTGSNSNDFAFSMRRGVGITGKYDG
HHCCEEEEEEEECCCCEEECCCCCCCCEEEEEEEEEECCCCCCEEEEHHCCCCCCCCCCC
LLKNNTLASYIHTHTACLPDFGYNFTQSAYENK
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA