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The map label for this gene is mtd

Identifier: 84488992

GI number: 84488992

Start: 204244

End: 205074

Strand: Direct

Name: mtd

Synonym: Msp_0163

Alternate gene names: 84488992

Gene position: 204244-205074 (Clockwise)

Preceding gene: 84488991

Following gene: 84488995

Centisome position: 11.56

GC content: 32.85

Gene sequence:

>831_bases
ATGGTAGTAAAAATAGGAATTGTAAAAGTTGGTAACATAGGAACATCTGTATTAATAGACATGATATTAGATGAAAGAGC
AGATAGGGAAGATATTGATGTGAGAACAATAAGTTCTGGAGCTAAAATGGGTAAAAATCAGATGGATGATGTTTTACCAA
AGATTGATGAGTATAATCCAGATGTTATTATATTTATTAGTCCAGATCCTGGAGCTAAATCCCCATCCTCTGCAAGAGAA
ACACTATCTAAAAAGAATATTCCAACAATTGTAATTGGTGATGGACCAGGGGAACGTGCAATTGGTTCTATGAAGGAACA
AGGTCTTGGATATATTATAGTAAAGGCTGATTCAATGATTGGAGCAAGAAGAGAATTTTTGGATGCTACAGAAATGGCAG
TATTTAATTCTGATGTCTTGATGGTACTCTCAACAACTGGTGTATTTAGATTAATTCATAAAACATTAGATAAAGTAATA
CGGGATATTGATGAAGATAAATTATATTCACTACCAGAACTTGTTATTACTGCGGAAAATGCTGTGGATGCAGCTGACTT
TAAAAATCCATATGCTAAAAGTAAAGCTATTGCAGCATATTCCATTGCATGTCAGGTATCTTCTATGAATGTAAGAGCTT
GTTTTAAAACAAAGGATTATCATGTTTATATTCCACTTGTAAGTGCTGCTCATGAAATGATGTCTGCAGCATCAAAACTT
GCATATGAAGCAAGAGAAATAGAAAAAAGTAATGATACTGTTGTTAGAACAGCTCATAGAAGAAATGGATCCATATTATA
TGGGACTTCGTTAAATGATAATAAAGAATAG

Upstream 100 bases:

>100_bases
CCAGATTTTGGATATAATTTTACACAGTCTGCATATGAAAATAAATAAAATAATATAAAAAAAATAAGTATAGAATTTAT
GTAATAATAAGAGTGAAATC

Downstream 100 bases:

>100_bases
ATACTTATAATAAAGTGTAGGGAAAGTTCTATAATTTTCCCTTTGTACTTAATATTTGATTATGTGTGATTTTTGTAGCA
TCATTTAAGCTACGTGCTAA

Product: F420-dependent methylenetetrahydromethanopterin dehydrogenase

Products: NA

Alternate protein names: MTD; Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MVVKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDVLPKIDEYNPDVIIFISPDPGAKSPSSARE
TLSKKNIPTIVIGDGPGERAIGSMKEQGLGYIIVKADSMIGARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVI
RDIDEDKLYSLPELVITAENAVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKL
AYEAREIEKSNDTVVRTAHRRNGSILYGTSLNDNKE

Sequences:

>Translated_276_residues
MVVKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDVLPKIDEYNPDVIIFISPDPGAKSPSSARE
TLSKKNIPTIVIGDGPGERAIGSMKEQGLGYIIVKADSMIGARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVI
RDIDEDKLYSLPELVITAENAVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKL
AYEAREIEKSNDTVVRTAHRRNGSILYGTSLNDNKE
>Mature_276_residues
MVVKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDVLPKIDEYNPDVIIFISPDPGAKSPSSARE
TLSKKNIPTIVIGDGPGERAIGSMKEQGLGYIIVKADSMIGARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVI
RDIDEDKLYSLPELVITAENAVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKL
AYEAREIEKSNDTVVRTAHRRNGSILYGTSLNDNKE

Specific function: Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT(+)

COG id: COG1927

COG function: function code C; Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTD_METST (Q2NHQ2)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447224.1
- ProteinModelPortal:   Q2NHQ2
- SMR:   Q2NHQ2
- STRING:   Q2NHQ2
- GeneID:   3856037
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0163
- NMPDR:   fig|339860.6.peg.161
- eggNOG:   arNOG04866
- HOGENOM:   HBG538567
- OMA:   IVASAHE
- ProtClustDB:   PRK00994
- BioCyc:   MSTA339860:MSP_0163-MONOMER
- GO:   GO:0015948
- HAMAP:   MF_00058
- InterPro:   IPR002844
- PIRSF:   PIRSF005627
- ProDom:   PD017604

Pfam domain/function: PF01993 MTD; SSF102324 MeTD

EC number: =1.5.99.9

Molecular weight: Translated: 30221; Mature: 30221

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDVLPKIDEYNP
CEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHCCCHHHHHHHHHCCCCCC
DVIIFISPDPGAKSPSSARETLSKKNIPTIVIGDGPGERAIGSMKEQGLGYIIVKADSMI
CEEEEECCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCEEEEECCCHH
GARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVIRDIDEDKLYSLPELVITAEN
HHHHHHHHHHHHHEECCCEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEECC
AVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKL
CCCHHHCCCCCHHCHHEEEEEEEEEEECCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHH
AYEAREIEKSNDTVVRTAHRRNGSILYGTSLNDNKE
HHHHHHHCCCCCEEEEEEECCCCCEEEECCCCCCCC
>Mature Secondary Structure
MVVKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDVLPKIDEYNP
CEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHCCCHHHHHHHHHCCCCCC
DVIIFISPDPGAKSPSSARETLSKKNIPTIVIGDGPGERAIGSMKEQGLGYIIVKADSMI
CEEEEECCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCEEEEECCCHH
GARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVIRDIDEDKLYSLPELVITAEN
HHHHHHHHHHHHHEECCCEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEECC
AVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKL
CCCHHHCCCCCHHCHHEEEEEEEEEEECCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHH
AYEAREIEKSNDTVVRTAHRRNGSILYGTSLNDNKE
HHHHHHHCCCCCEEEEEEECCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA