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The map label for this gene is galE [C]

Identifier: 78779718

GI number: 78779718

Start: 1248757

End: 1249710

Strand: Reverse

Name: galE [C]

Synonym: PMT9312_1334

Alternate gene names: 78779718

Gene position: 1249710-1248757 (Counterclockwise)

Preceding gene: 78779719

Following gene: 78779717

Centisome position: 73.12

GC content: 28.2

Gene sequence:

>954_bases
TTGAAGAAAAATTTTTTGATTACCGGTGGTGCTGGTTTTATAGGTTCTAACTTAATTAATAAACTTCTAGAAATTCCAGA
AAATAATGTTTTTGTATTTGATAATTTATCAACTGGTAGAAAAACAAATCTTAAACTGGATAATAAAAATTTAAATTTTT
ATAATATAGATCTAAAAACTCCATATAGAGATTGGCCTCAATTAAAAGAAATTGATACTTTATTTCATTTCGCTGCAAAT
GCAGATGTAAGAGGTGGTGAGATTAATAGAGATATTGATTTTTATGAGAATGTTATTGTGACAAAAGCTATTTGCGATTA
TGCCTCGAAAAATAAAATAAAAAAGGTGGCCTTTTCTAGTAGTGCAACAGTATATGGAGAGCCAAATATATTTCCTACTC
CTGAGAATTATTCTTCAACTCAAACTTCTGTATATGGAGCAAGTAAATTAGCGGGAGAAGCATATCTTCAGGCTTATTCA
GAGTACTTGGATTTTAAAGTAACTATATTTAGATTCGTTTCTTGGGTTGGTTATGGTTATTCTCATGGTGTAATTTATGA
TTTTGTAAATAAATTACTTAAAAATCCAAATGAACTTTTTATTTTAGGTGATGGGAATCAAAAAAAATCATACCTTGATG
TTAGTGATGGAGTTAATGGCGTCTTAAATTTAAATGATTTAAATCAAGAAAATTGTAATATTTTTAATTTGGGTCATACT
GAGATTATCGATGTAAATAGTTTGGCAAGAATTATATGTAAGAAATTGGATTTGATAAATATTAAATTTAATTATTCTGG
GGGTGAAAGAGGCTGGAAGGGTGATTCTCCTTTAGTACATTTAGACATTTCTAAAGCTAAAAAATATGGTTGGTCCCCTA
AAGTTGATATAAAAACCGCAATCTCCAATACTGTTGATTATCTTTTAAGTGACAGAAGAAATTTATATAGATAA

Upstream 100 bases:

>100_bases
GCTGCTATGAATTCCGGAATGAAATTTATAGATATTGAAGATTTATAGATACCTTAATAATAAATTTGATATAGTGTAAA
ATTATAAATTATAAATAAAA

Downstream 100 bases:

>100_bases
TATGAAGAATTTTAATAAATTTTTTTGGTTGAATTTGCAAATTAAACAATGAATATCTTTTTTTCAATAATAATCCCAGT
TTTTAATAGGCCATTTGAAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKKNFLITGGAGFIGSNLINKLLEIPENNVFVFDNLSTGRKTNLKLDNKNLNFYNIDLKTPYRDWPQLKEIDTLFHFAAN
ADVRGGEINRDIDFYENVIVTKAICDYASKNKIKKVAFSSSATVYGEPNIFPTPENYSSTQTSVYGASKLAGEAYLQAYS
EYLDFKVTIFRFVSWVGYGYSHGVIYDFVNKLLKNPNELFILGDGNQKKSYLDVSDGVNGVLNLNDLNQENCNIFNLGHT
EIIDVNSLARIICKKLDLINIKFNYSGGERGWKGDSPLVHLDISKAKKYGWSPKVDIKTAISNTVDYLLSDRRNLYR

Sequences:

>Translated_317_residues
MKKNFLITGGAGFIGSNLINKLLEIPENNVFVFDNLSTGRKTNLKLDNKNLNFYNIDLKTPYRDWPQLKEIDTLFHFAAN
ADVRGGEINRDIDFYENVIVTKAICDYASKNKIKKVAFSSSATVYGEPNIFPTPENYSSTQTSVYGASKLAGEAYLQAYS
EYLDFKVTIFRFVSWVGYGYSHGVIYDFVNKLLKNPNELFILGDGNQKKSYLDVSDGVNGVLNLNDLNQENCNIFNLGHT
EIIDVNSLARIICKKLDLINIKFNYSGGERGWKGDSPLVHLDISKAKKYGWSPKVDIKTAISNTVDYLLSDRRNLYR
>Mature_317_residues
MKKNFLITGGAGFIGSNLINKLLEIPENNVFVFDNLSTGRKTNLKLDNKNLNFYNIDLKTPYRDWPQLKEIDTLFHFAAN
ADVRGGEINRDIDFYENVIVTKAICDYASKNKIKKVAFSSSATVYGEPNIFPTPENYSSTQTSVYGASKLAGEAYLQAYS
EYLDFKVTIFRFVSWVGYGYSHGVIYDFVNKLLKNPNELFILGDGNQKKSYLDVSDGVNGVLNLNDLNQENCNIFNLGHT
EIIDVNSLARIICKKLDLINIKFNYSGGERGWKGDSPLVHLDISKAKKYGWSPKVDIKTAISNTVDYLLSDRRNLYR

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=321, Percent_Identity=28.0373831775701, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI7657641, Length=327, Percent_Identity=26.9113149847095, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=27.0029673590504, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17539532, Length=321, Percent_Identity=27.7258566978193, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI115532424, Length=345, Percent_Identity=27.536231884058, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=306, Percent_Identity=29.0849673202614, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356223, Length=321, Percent_Identity=28.0373831775701, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19923002, Length=167, Percent_Identity=35.3293413173653, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35862; Mature: 35862

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNFLITGGAGFIGSNLINKLLEIPENNVFVFDNLSTGRKTNLKLDNKNLNFYNIDLKT
CCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCEEEEEEECC
PYRDWPQLKEIDTLFHFAANADVRGGEINRDIDFYENVIVTKAICDYASKNKIKKVAFSS
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECC
SATVYGEPNIFPTPENYSSTQTSVYGASKLAGEAYLQAYSEYLDFKVTIFRFVSWVGYGY
CEEEEECCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCC
SHGVIYDFVNKLLKNPNELFILGDGNQKKSYLDVSDGVNGVLNLNDLNQENCNIFNLGHT
CCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCCEEEECCCCCCCCCEEECCCC
EIIDVNSLARIICKKLDLINIKFNYSGGERGWKGDSPLVHLDISKAKKYGWSPKVDIKTA
EEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHCCCCCCCCHHHH
ISNTVDYLLSDRRNLYR
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKNFLITGGAGFIGSNLINKLLEIPENNVFVFDNLSTGRKTNLKLDNKNLNFYNIDLKT
CCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCEEEEEEECC
PYRDWPQLKEIDTLFHFAANADVRGGEINRDIDFYENVIVTKAICDYASKNKIKKVAFSS
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECC
SATVYGEPNIFPTPENYSSTQTSVYGASKLAGEAYLQAYSEYLDFKVTIFRFVSWVGYGY
CEEEEECCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCC
SHGVIYDFVNKLLKNPNELFILGDGNQKKSYLDVSDGVNGVLNLNDLNQENCNIFNLGHT
CCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCCEEEECCCCCCCCCEEECCCC
EIIDVNSLARIICKKLDLINIKFNYSGGERGWKGDSPLVHLDISKAKKYGWSPKVDIKTA
EEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHCCCCCCCCHHHH
ISNTVDYLLSDRRNLYR
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]