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The map label for this gene is glmM [H]

Identifier: 78778665

GI number: 78778665

Start: 268019

End: 269473

Strand: Direct

Name: glmM [H]

Synonym: PMT9312_0280

Alternate gene names: 78778665

Gene position: 268019-269473 (Clockwise)

Preceding gene: 78778663

Following gene: 78778666

Centisome position: 15.68

GC content: 29.42

Gene sequence:

>1455_bases
TTGGCAGGTGAAACATTAGATAACATAAAATTTGGAACTGATGGGTGGAGAGGAATTATTGGATTTGATTTTAATATTTC
CAATCTTTCAAGGGTTGTAGTGGCGGCATGCCAGGAGTTGCATTATCAATTTCATAAAGAAGTTAATTCAAAGAAAATTT
TAATTGGATATGATCGTAGATTTATGGCAATTGAATTTGCCAAGCAAATAGTTCCTTTCGTAAAAGGATGTGGTTTTGAA
CCTATCTTGTCTAATAGTTTTGTTACAACGCCTTCTTGTAGTTTTTATGCTAAAGAAATGAATTGTTTGGGAGCTTTAGT
TATTACAGCAAGTCATAATCCATACAATTGGTTGGGTCTAAAAATAAAAAGTTTTAATGGATGTTCTGTTGATGAATCTT
TTACAACTGAAATTGAAAAAAGATTAATGCTTGGTAATGCAATTGATAAACTAGAGGATTCATATGAAATTGCGGATGTT
AAGAAGTTACATTTAGATAGAATTAAATCTCTTTTTGATATTGAATTTATTGCTAATCAATTGAAAAAAATGAATATGAG
GATTTTTGTCGATTCTATGCATGGTTCAGCTGCAAAATGCATAGCTGAGATTTTTGGTGGTAATGATTCAGAAGTAGTTT
CAGAAATTAGAGAAGATGCTGATCCTTTTTTTGGAGGAAATCCTCCCGAGCCTCTTTTAAATTATTTAGATGACTTAAAT
GAAACACTTATAAAAAATTCAAAAAATGAAGTAAAAACTTTAGGAATTATATTTGATGGAGATGGTGACAGAATTGCGGC
AATTGATGAAAAAGGTAGATACTGTAGTACACAAGATTTATTACCATACTTTATTAGCTATTTGGGAGAAATTAACCATA
ATTCTTATCCAGTTTTAAAGACTGTTAGTGGTTCAGATATTATTAAAAATATATCAGAGAGCCAAAATAGAGATGTTTTT
GAACTTCCAGTTGGCTTTAAATATATTGCTGAAAAAATGATTAAAGAGAAAATATTTATTGGAGGAGAGGAATCTGGGGG
AGTTGGTTTTGGTAACTTTATGCCTGAAAGAGATGCTCTATATGCAGCGATAGTTTTATTAAATGGAATTGCTGAAAAAT
CTCAATATTTATATGAAACTTTAGATGAAATTCAAAAAGATTTTGGACCAAGTGTTTATAAAAGAATTGATATTAAATTT
CCAAATCAGTCAGAAAAAAATAACGTAAAAGAATTTATCATAGATAATATTCCTGAGAATATTAATAATCACAAGTTAAA
AAGTATCTCAAAGATTGATGGAATAAAGTTGAGAATTGATAAAAATTTTTGGCTTCTTTTTAGGTTTTCAGGAACGGAAC
CTCTTTTAAGGTTATATTGTGAAGCACCAAAAGAATCTTATTTAGATGAGTTATTAGAGTGGGGTCAAGTATTTATAAAT
TTGGCAGGAAAATAA

Upstream 100 bases:

>100_bases
TTTTAAATAAAGAGTATTCAAATTATTTTGAAGCTTAGTTTTAAAAATTACTTATATAAATTAATATAGATAATTAAAAC
AAATAAAGGAACTTTTAAAT

Downstream 100 bases:

>100_bases
GGATGAAAAATTTATATTTAGCGAGTAAGAATAAAGGTAAAATTGAAGAATATAAGAAATTGCTTGCTGGAGTTAATTGT
AAATTATTACTCCAGCCAGA

Product: phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MAGETLDNIKFGTDGWRGIIGFDFNISNLSRVVVAACQELHYQFHKEVNSKKILIGYDRRFMAIEFAKQIVPFVKGCGFE
PILSNSFVTTPSCSFYAKEMNCLGALVITASHNPYNWLGLKIKSFNGCSVDESFTTEIEKRLMLGNAIDKLEDSYEIADV
KKLHLDRIKSLFDIEFIANQLKKMNMRIFVDSMHGSAAKCIAEIFGGNDSEVVSEIREDADPFFGGNPPEPLLNYLDDLN
ETLIKNSKNEVKTLGIIFDGDGDRIAAIDEKGRYCSTQDLLPYFISYLGEINHNSYPVLKTVSGSDIIKNISESQNRDVF
ELPVGFKYIAEKMIKEKIFIGGEESGGVGFGNFMPERDALYAAIVLLNGIAEKSQYLYETLDEIQKDFGPSVYKRIDIKF
PNQSEKNNVKEFIIDNIPENINNHKLKSISKIDGIKLRIDKNFWLLFRFSGTEPLLRLYCEAPKESYLDELLEWGQVFIN
LAGK

Sequences:

>Translated_484_residues
MAGETLDNIKFGTDGWRGIIGFDFNISNLSRVVVAACQELHYQFHKEVNSKKILIGYDRRFMAIEFAKQIVPFVKGCGFE
PILSNSFVTTPSCSFYAKEMNCLGALVITASHNPYNWLGLKIKSFNGCSVDESFTTEIEKRLMLGNAIDKLEDSYEIADV
KKLHLDRIKSLFDIEFIANQLKKMNMRIFVDSMHGSAAKCIAEIFGGNDSEVVSEIREDADPFFGGNPPEPLLNYLDDLN
ETLIKNSKNEVKTLGIIFDGDGDRIAAIDEKGRYCSTQDLLPYFISYLGEINHNSYPVLKTVSGSDIIKNISESQNRDVF
ELPVGFKYIAEKMIKEKIFIGGEESGGVGFGNFMPERDALYAAIVLLNGIAEKSQYLYETLDEIQKDFGPSVYKRIDIKF
PNQSEKNNVKEFIIDNIPENINNHKLKSISKIDGIKLRIDKNFWLLFRFSGTEPLLRLYCEAPKESYLDELLEWGQVFIN
LAGK
>Mature_483_residues
AGETLDNIKFGTDGWRGIIGFDFNISNLSRVVVAACQELHYQFHKEVNSKKILIGYDRRFMAIEFAKQIVPFVKGCGFEP
ILSNSFVTTPSCSFYAKEMNCLGALVITASHNPYNWLGLKIKSFNGCSVDESFTTEIEKRLMLGNAIDKLEDSYEIADVK
KLHLDRIKSLFDIEFIANQLKKMNMRIFVDSMHGSAAKCIAEIFGGNDSEVVSEIREDADPFFGGNPPEPLLNYLDDLNE
TLIKNSKNEVKTLGIIFDGDGDRIAAIDEKGRYCSTQDLLPYFISYLGEINHNSYPVLKTVSGSDIIKNISESQNRDVFE
LPVGFKYIAEKMIKEKIFIGGEESGGVGFGNFMPERDALYAAIVLLNGIAEKSQYLYETLDEIQKDFGPSVYKRIDIKFP
NQSEKNNVKEFIIDNIPENINNHKLKSISKIDGIKLRIDKNFWLLFRFSGTEPLLRLYCEAPKESYLDELLEWGQVFINL
AGK

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=483, Percent_Identity=24.4306418219462, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI21361621, Length=476, Percent_Identity=24.5798319327731, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI133922562, Length=476, Percent_Identity=23.7394957983193, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI290463104, Length=333, Percent_Identity=24.3243243243243, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1789566, Length=475, Percent_Identity=22.5263157894737, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17535441, Length=524, Percent_Identity=24.236641221374, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323752, Length=399, Percent_Identity=25.31328320802, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6322722, Length=492, Percent_Identity=24.7967479674797, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6323934, Length=408, Percent_Identity=24.5098039215686, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864244, Length=546, Percent_Identity=23.8095238095238, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI20129809, Length=531, Percent_Identity=23.9171374764595, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24651977, Length=423, Percent_Identity=25.2955082742317, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 54778; Mature: 54647

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGETLDNIKFGTDGWRGIIGFDFNISNLSRVVVAACQELHYQFHKEVNSKKILIGYDRR
CCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCH
FMAIEFAKQIVPFVKGCGFEPILSNSFVTTPSCSFYAKEMNCLGALVITASHNPYNWLGL
HHHHHHHHHHHHHHHCCCCCCHHCCCEECCCCCHHHHHHHHCCEEEEEEECCCCCEEEEE
KIKSFNGCSVDESFTTEIEKRLMLGNAIDKLEDSYEIADVKKLHLDRIKSLFDIEFIANQ
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKMNMRIFVDSMHGSAAKCIAEIFGGNDSEVVSEIREDADPFFGGNPPEPLLNYLDDLN
HHHCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ETLIKNSKNEVKTLGIIFDGDGDRIAAIDEKGRYCSTQDLLPYFISYLGEINHNSYPVLK
HHHHHCCCCCEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
TVSGSDIIKNISESQNRDVFELPVGFKYIAEKMIKEKIFIGGEESGGVGFGNFMPERDAL
ECCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHH
YAAIVLLNGIAEKSQYLYETLDEIQKDFGPSVYKRIDIKFPNQSEKNNVKEFIIDNIPEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCHHHHHHHHCCCCC
INNHKLKSISKIDGIKLRIDKNFWLLFRFSGTEPLLRLYCEAPKESYLDELLEWGQVFIN
CCCHHHHHHHHCCCEEEEEECCEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHE
LAGK
ECCC
>Mature Secondary Structure 
AGETLDNIKFGTDGWRGIIGFDFNISNLSRVVVAACQELHYQFHKEVNSKKILIGYDRR
CCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCH
FMAIEFAKQIVPFVKGCGFEPILSNSFVTTPSCSFYAKEMNCLGALVITASHNPYNWLGL
HHHHHHHHHHHHHHHCCCCCCHHCCCEECCCCCHHHHHHHHCCEEEEEEECCCCCEEEEE
KIKSFNGCSVDESFTTEIEKRLMLGNAIDKLEDSYEIADVKKLHLDRIKSLFDIEFIANQ
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKMNMRIFVDSMHGSAAKCIAEIFGGNDSEVVSEIREDADPFFGGNPPEPLLNYLDDLN
HHHCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ETLIKNSKNEVKTLGIIFDGDGDRIAAIDEKGRYCSTQDLLPYFISYLGEINHNSYPVLK
HHHHHCCCCCEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
TVSGSDIIKNISESQNRDVFELPVGFKYIAEKMIKEKIFIGGEESGGVGFGNFMPERDAL
ECCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHH
YAAIVLLNGIAEKSQYLYETLDEIQKDFGPSVYKRIDIKFPNQSEKNNVKEFIIDNIPEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCHHHHHHHHCCCCC
INNHKLKSISKIDGIKLRIDKNFWLLFRFSGTEPLLRLYCEAPKESYLDELLEWGQVFIN
CCCHHHHHHHHCCCEEEEEECCEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHE
LAGK
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]