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The map label for this gene is yggV [C]

Identifier: 78778666

GI number: 78778666

Start: 269476

End: 270051

Strand: Direct

Name: yggV [C]

Synonym: PMT9312_0281

Alternate gene names: 78778666

Gene position: 269476-270051 (Clockwise)

Preceding gene: 78778665

Following gene: 78778670

Centisome position: 15.77

GC content: 31.25

Gene sequence:

>576_bases
ATGAAAAATTTATATTTAGCGAGTAAGAATAAAGGTAAAATTGAAGAATATAAGAAATTGCTTGCTGGAGTTAATTGTAA
ATTATTACTCCAGCCAGAATCATTAGAAGTTGAAGAGGATGGAATGACATTTCGAGATAATGCAATTAAAAAAGCGAGTG
AAGTTTCTAGAAAAACAAATAATTTCTCAATAGCTGATGATTCAGGAATTTGTATTGAAGCACTAGATGGTAAGCCTGGC
ATTTACTCATCTAGATATGCAGAAAATGATCAGAAGAGAATTGAACGAGTTTTAAAAGAACTTGATGGAGTTCAAAGTAG
AAGTGCTTTCTTTATTGCCAATATTTGTGTTTGTTCCCCAAATGGTGAAGTGATTATTGAATCTGAGGCCAAATGTCATG
GCAATATTATTTTAAACCCGAGAGGGAAAGGTGGTTTTGGGTATGACCCAATTTTTGAGGAGAGTTCTACCAGATTAACT
TTTGCAGAAATGAATAATGATATTAAAGACTCTTGTAGTCATAGAGGTAAAGCATTAAAAAAAATTATTCCAGATTTAAT
TGAAATTTTTTCTTAA

Upstream 100 bases:

>100_bases
AACCTCTTTTAAGGTTATATTGTGAAGCACCAAAAGAATCTTATTTAGATGAGTTATTAGAGTGGGGTCAAGTATTTATA
AATTTGGCAGGAAAATAAGG

Downstream 100 bases:

>100_bases
ATTCAATTAACCCAAGATCCATGAAGGCCATGAGGAATTGAAATGGGTAATTCATAAACAGCTAATTCTTTTAAGTCTTT
TGCATCTAATATCACTAAAT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MKNLYLASKNKGKIEEYKKLLAGVNCKLLLQPESLEVEEDGMTFRDNAIKKASEVSRKTNNFSIADDSGICIEALDGKPG
IYSSRYAENDQKRIERVLKELDGVQSRSAFFIANICVCSPNGEVIIESEAKCHGNIILNPRGKGGFGYDPIFEESSTRLT
FAEMNNDIKDSCSHRGKALKKIIPDLIEIFS

Sequences:

>Translated_191_residues
MKNLYLASKNKGKIEEYKKLLAGVNCKLLLQPESLEVEEDGMTFRDNAIKKASEVSRKTNNFSIADDSGICIEALDGKPG
IYSSRYAENDQKRIERVLKELDGVQSRSAFFIANICVCSPNGEVIIESEAKCHGNIILNPRGKGGFGYDPIFEESSTRLT
FAEMNNDIKDSCSHRGKALKKIIPDLIEIFS
>Mature_191_residues
MKNLYLASKNKGKIEEYKKLLAGVNCKLLLQPESLEVEEDGMTFRDNAIKKASEVSRKTNNFSIADDSGICIEALDGKPG
IYSSRYAENDQKRIERVLKELDGVQSRSAFFIANICVCSPNGEVIIESEAKCHGNIILNPRGKGGFGYDPIFEESSTRLT
FAEMNNDIKDSCSHRGKALKKIIPDLIEIFS

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=195, Percent_Identity=38.4615384615385, Blast_Score=114, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17556833, Length=182, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19920712, Length=178, Percent_Identity=29.2134831460674, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21257; Mature: 21257

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLYLASKNKGKIEEYKKLLAGVNCKLLLQPESLEVEEDGMTFRDNAIKKASEVSRKTN
CCCEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHCCC
NFSIADDSGICIEALDGKPGIYSSRYAENDQKRIERVLKELDGVQSRSAFFIANICVCSP
CEEEECCCCCEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEECC
NGEVIIESEAKCHGNIILNPRGKGGFGYDPIFEESSTRLTFAEMNNDIKDSCSHRGKALK
CCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHH
KIIPDLIEIFS
HHHHHHHHHCC
>Mature Secondary Structure
MKNLYLASKNKGKIEEYKKLLAGVNCKLLLQPESLEVEEDGMTFRDNAIKKASEVSRKTN
CCCEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHCCC
NFSIADDSGICIEALDGKPGIYSSRYAENDQKRIERVLKELDGVQSRSAFFIANICVCSP
CEEEECCCCCEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEECC
NGEVIIESEAKCHGNIILNPRGKGGFGYDPIFEESSTRLTFAEMNNDIKDSCSHRGKALK
CCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHH
KIIPDLIEIFS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]