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The map label for this gene is fdhE [H]

Identifier: 78355753

GI number: 78355753

Start: 723932

End: 724813

Strand: Direct

Name: fdhE [H]

Synonym: Dde_0706

Alternate gene names: 78355753

Gene position: 723932-724813 (Clockwise)

Preceding gene: 78355749

Following gene: 78355754

Centisome position: 19.41

GC content: 59.3

Gene sequence:

>882_bases
ATGAATTTTGATCTGGAAAAGGAACGCCGCGGGTTGGATCGCAAACTGGAAGCATTGCGGAAAAAAGAATTCATTCCCGC
TGCGTTACTGGATATTGTAGCCAGAACCGCGCAACTGCAGCTTGAAGCACGGGCCAAAGTGCAGGTGACGCTGCCCGCCG
GACTTACTGCGGCCGATACCCACGCACAGGGTGCCCCCCTGCTGCCGCGTGAACATTTTCCCTATGACAAGGCGGTCACC
GCCGAAACGTTCGGCAAACTGCTGGCGCTGATGGCCGCATCGGGCGGATCCATGGCGGCAGGAGCGCAGGCGCTGCACAA
GGCGCTTGAGGCCCGTGAGTTTTCGCTGGAAGAAGCCTGCAGTGCCCTGCTGCAGGACGACCAGCTGTTTTTTGCCGACT
GGAGCGCCCGCATGCCGGAAGCTCCCAGCTTTGTGCGGTTTCTCGTGCAGGGCAGCATGGTACCTTCGCTTATGGCCGTT
TCCGACCTGCTGGCGCAGCAGCGTGACACTGCGTCCGTGTGGGCGCACGGGCACTGTCCGCATTGCGGTTCCATGCCGCT
TGTGGCCTCGCTTAAGCAGAAAGAGGGCTTCCGCTATCTTACCTGCTCGCTGTGCCGCCACGAATACAGAGCCAAAAGAC
TGCAGTGTCCTTTCTGCGGCGAAGACGACCACAAAAAGCTCGAATACTTCAAGGCAGAGGGTGAACCGGGGTTTGAGGTG
CATGTGTGCCGCAGCTGCCACTGCTACCTGAAAACATCGGATTTCCGCGATATGGACCGGCAGTCCGTTCCTGTGCTGGA
TGATCTGGAATCGCTGGCACTGGATATCCTTGCCCGTGAACAGGGCTTTGTCCGGCCGACCCAGTCTGCATGGGGGTTCT
GA

Upstream 100 bases:

>100_bases
AACGCAGGAAGCGCGGTGTTGTTTACGGTGCCGCTACGTGCCACATGTTGTTCACGGCCGCCTGTGCGGCCACAGACTAC
CAGAGATACAAGGACTGCTC

Downstream 100 bases:

>100_bases
TCATGTCGGGCACAGATGGCGGGGCTGTGCCCCGCAATGTGGGGGTGCGCCGCTACAGCGACGGCAGCTGGCACATGGTG
GACGATGTTCTGAGCCGTGA

Product: formate dehydrogenase formation protein FdhE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNFDLEKERRGLDRKLEALRKKEFIPAALLDIVARTAQLQLEARAKVQVTLPAGLTAADTHAQGAPLLPREHFPYDKAVT
AETFGKLLALMAASGGSMAAGAQALHKALEAREFSLEEACSALLQDDQLFFADWSARMPEAPSFVRFLVQGSMVPSLMAV
SDLLAQQRDTASVWAHGHCPHCGSMPLVASLKQKEGFRYLTCSLCRHEYRAKRLQCPFCGEDDHKKLEYFKAEGEPGFEV
HVCRSCHCYLKTSDFRDMDRQSVPVLDDLESLALDILAREQGFVRPTQSAWGF

Sequences:

>Translated_293_residues
MNFDLEKERRGLDRKLEALRKKEFIPAALLDIVARTAQLQLEARAKVQVTLPAGLTAADTHAQGAPLLPREHFPYDKAVT
AETFGKLLALMAASGGSMAAGAQALHKALEAREFSLEEACSALLQDDQLFFADWSARMPEAPSFVRFLVQGSMVPSLMAV
SDLLAQQRDTASVWAHGHCPHCGSMPLVASLKQKEGFRYLTCSLCRHEYRAKRLQCPFCGEDDHKKLEYFKAEGEPGFEV
HVCRSCHCYLKTSDFRDMDRQSVPVLDDLESLALDILAREQGFVRPTQSAWGF
>Mature_293_residues
MNFDLEKERRGLDRKLEALRKKEFIPAALLDIVARTAQLQLEARAKVQVTLPAGLTAADTHAQGAPLLPREHFPYDKAVT
AETFGKLLALMAASGGSMAAGAQALHKALEAREFSLEEACSALLQDDQLFFADWSARMPEAPSFVRFLVQGSMVPSLMAV
SDLLAQQRDTASVWAHGHCPHCGSMPLVASLKQKEGFRYLTCSLCRHEYRAKRLQCPFCGEDDHKKLEYFKAEGEPGFEV
HVCRSCHCYLKTSDFRDMDRQSVPVLDDLESLALDILAREQGFVRPTQSAWGF

Specific function: Necessary for formate dehydrogenase activity [H]

COG id: COG3058

COG function: function code O; Uncharacterized protein involved in formate dehydrogenase formation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhE family [H]

Homologues:

Organism=Escherichia coli, GI1790324, Length=241, Percent_Identity=31.1203319502075, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006452 [H]

Pfam domain/function: PF04216 FdhE [H]

EC number: NA

Molecular weight: Translated: 32631; Mature: 32631

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDLEKERRGLDRKLEALRKKEFIPAALLDIVARTAQLQLEARAKVQVTLPAGLTAADT
CCCCCCHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEECEEEEEEECCCCCCCCC
HAQGAPLLPREHFPYDKAVTAETFGKLLALMAASGGSMAAGAQALHKALEAREFSLEEAC
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHH
SALLQDDQLFFADWSARMPEAPSFVRFLVQGSMVPSLMAVSDLLAQQRDTASVWAHGHCP
HHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEECCCCC
HCGSMPLVASLKQKEGFRYLTCSLCRHEYRAKRLQCPFCGEDDHKKLEYFKAEGEPGFEV
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEE
HVCRSCHCYLKTSDFRDMDRQSVPVLDDLESLALDILAREQGFVRPTQSAWGF
EEECCCEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCC
>Mature Secondary Structure
MNFDLEKERRGLDRKLEALRKKEFIPAALLDIVARTAQLQLEARAKVQVTLPAGLTAADT
CCCCCCHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEECEEEEEEECCCCCCCCC
HAQGAPLLPREHFPYDKAVTAETFGKLLALMAASGGSMAAGAQALHKALEAREFSLEEAC
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHH
SALLQDDQLFFADWSARMPEAPSFVRFLVQGSMVPSLMAVSDLLAQQRDTASVWAHGHCP
HHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEECCCCC
HCGSMPLVASLKQKEGFRYLTCSLCRHEYRAKRLQCPFCGEDDHKKLEYFKAEGEPGFEV
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEE
HVCRSCHCYLKTSDFRDMDRQSVPVLDDLESLALDILAREQGFVRPTQSAWGF
EEECCCEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]