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The map label for this gene is ctpC [H]

Identifier: 78355545

GI number: 78355545

Start: 504674

End: 506776

Strand: Direct

Name: ctpC [H]

Synonym: Dde_0498

Alternate gene names: 78355545

Gene position: 504674-506776 (Clockwise)

Preceding gene: 78355544

Following gene: 78355553

Centisome position: 13.53

GC content: 63.05

Gene sequence:

>2103_bases
GTGGCACAGTATCCTTTGCCGCAGCTTGTACACCGCACCCGCGGCAGATTGCGCTACAGGTGGCGCAGGCTGTCCGACCC
CGCGCTTGATCCGGAGTATTTTGAAGCATGGCTTGAAAATACAGAAGGTGTGGCGCGGGCCAGAGTGAACCCCCGCGCCG
CCTGTGTGGTGATAGAGCTTGCCCCGCAGGGGAGCGGGGCGGATTTCGGCAACGTGCTGCTGCGGGTACCGGCACGGGCT
TTTTCGCGCGGGGTGCCCGCACCGCCGCGCAGAGGTCTGGGCGATGCGGTGTTTCATGCGGCAATGACCGCAGCTGTTGC
CGCGATGCCGCCCGGGCTGCAACTGCCGGTGGCGGCCGCAATGGGCGCTCCGGCAGTGCTGAAAGGGGCTGAAACGCTGC
TCACTCAGGGACTCAAGGTGCGGGTGCTGGACATGGCGACCATAGGCTTTTCGCTGCTGCGCGGCGATTATGTGGCTGCC
GCGTCCATATCCACCATGGTTGTTGTGGGCGAATTTCTGCGTCAGGCAACCGAGGACCGCTCCAACGGGCTGCTGAAGAG
CCTTGTGGCCGCTCCTGTGGAGTCGGTATGGGTGCGCCGCGGAGATGCGGAGGTCGCCGTTGCCTTTGCCGATGTGGTTC
CCGGCGATCTGGTGCTTGCGGGCAGCGGCGGGCTGGTGGCTGTGGACGGACTGGTGGTGGCGGGTGAGGCTTTGCTGGAC
TGCAGTTCCATAACCGGAGAATCCGCTCCGGTGTATGTGAAGGAGGGGGCGGAGATTCTCTCCGGCTGCGTTGTCCGTGA
AGGCGCTGTGACCATTGAGGCCCGGCGTACCGGTGCCGAAACAAACATGGCCAGAATTTCGGGCTTTATGGAAAATGCGC
TGCGTGAAGTTTCGGCCAGAGAACGCCGCAGCGACAGGCTTGCGGACATGCTTGCCCCCATCACGCTTGGTCTGGGCGCC
GTCCTGTATGCCGCCACGCATGACGCCTCGCGCGCTCTTTCTGTTCTTACCATCGATTATGCCTGTGCGGTAAAGCTGCC
GGCGCCCGTGGTTATTAAAACTTCGCTGCATACCGCTGCCAGAGAGGGCGTGCTGATTAAAAGCGGCTCCGGACTGGATG
CGTTTGCAGAAGCCGACACTCTGGTTTTTGACAAGACCGGAACTCTGACCACAGGGCGGCTGCGGGTCACTGATGTGCTT
ACGGCCGGTATTGCTGATGATGAATTTATCCGTCTGGCCGCATCGGTGGAAGACCGGTCGGATCATCCCGTGGGGCAGGC
CGTGGTGGCGGAAGCGGCGCGCAGGGGCCTTGAGCTGCTGCCGGCGGGTAATGCCTGCTGCAGTATCGCACACGGCATAG
AGGCCGTGGTGGCCGGCCGCGTGGTGCGCGTGGGCAGCCATCACTACATTGCCGAAGACTGCGGCATCAGCTGCGCGGCA
CTGGCCGGAGAGGCTGAACGGTTGCGCAGTGAGGCCAAGACGCTGGTGTTTGTTGCTTCCGGCGAGTCGCTGCTGGGCCT
TATTGCCCTGCGCGACGAGATACGCCCCGAAGCATGCGATGTGCTGCGGCAGATGCGTTTGCGGGGCATACGGCATGTTT
ATGTGCTGACAGGCGATCATGCCCGGACTGCTGAGACTCTGCTTGCACAGGTGCCCGGTATTGACGGGATGCATACGGAC
CTGCTGCCGGAAGAAAAAGCCGCTTTTGTGAAAGACCTGCGGAGCAAAGGGCACAAGGTGGCCATGATCGGCGACGGCGT
GAACGATGCTCCCGCTTTTGTGGCGGCAGATGTGGGGGTGTCACTTTCACGCACGCAGGGGCTGGCCAGAGAATCGGCCC
GCATTGTGCTGCTGCGTGACTCTCTGCACGGGCTGGTGGTGGCGCGGGATACCGGCCTGAGGGCTGCGGGAATACTGGAT
AACTGCTTTATGGCAGGGGTGGGCATAAATACCGGCCTGCTGCTTGTGGCCGGTGCGGGGCTGCTGTCACCTGTTGCGGC
AGCTGCTGTTCATAATGCCACAACGTTCGCCATACTTGGCGGCTCAGCCTGGGCGGCCGGCAGACGGCCGGCAGCCGGAC
AGCAGACAGACCGGCGGAACTGA

Upstream 100 bases:

>100_bases
TGGAACTGGCGGAGCGTTCCGGCTTTACACTGAGCCGCCACAGGATGTTTCTGTACGGACTTTGCCCCGCATGCCGCCGT
AAAGGTATAAAGGACTGACC

Downstream 100 bases:

>100_bases
CCCCGCCGCGCAGACGGAATACAAAAAAGCCTTTCCCCGCGGAAAAGGCTTTTTTTTGTGTGTCAGCAGGATGTCAGGCT
TTTTCCTCTTTTACCGTCAC

Product: heavy metal translocating P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MAQYPLPQLVHRTRGRLRYRWRRLSDPALDPEYFEAWLENTEGVARARVNPRAACVVIELAPQGSGADFGNVLLRVPARA
FSRGVPAPPRRGLGDAVFHAAMTAAVAAMPPGLQLPVAAAMGAPAVLKGAETLLTQGLKVRVLDMATIGFSLLRGDYVAA
ASISTMVVVGEFLRQATEDRSNGLLKSLVAAPVESVWVRRGDAEVAVAFADVVPGDLVLAGSGGLVAVDGLVVAGEALLD
CSSITGESAPVYVKEGAEILSGCVVREGAVTIEARRTGAETNMARISGFMENALREVSARERRSDRLADMLAPITLGLGA
VLYAATHDASRALSVLTIDYACAVKLPAPVVIKTSLHTAAREGVLIKSGSGLDAFAEADTLVFDKTGTLTTGRLRVTDVL
TAGIADDEFIRLAASVEDRSDHPVGQAVVAEAARRGLELLPAGNACCSIAHGIEAVVAGRVVRVGSHHYIAEDCGISCAA
LAGEAERLRSEAKTLVFVASGESLLGLIALRDEIRPEACDVLRQMRLRGIRHVYVLTGDHARTAETLLAQVPGIDGMHTD
LLPEEKAAFVKDLRSKGHKVAMIGDGVNDAPAFVAADVGVSLSRTQGLARESARIVLLRDSLHGLVVARDTGLRAAGILD
NCFMAGVGINTGLLLVAGAGLLSPVAAAAVHNATTFAILGGSAWAAGRRPAAGQQTDRRN

Sequences:

>Translated_700_residues
MAQYPLPQLVHRTRGRLRYRWRRLSDPALDPEYFEAWLENTEGVARARVNPRAACVVIELAPQGSGADFGNVLLRVPARA
FSRGVPAPPRRGLGDAVFHAAMTAAVAAMPPGLQLPVAAAMGAPAVLKGAETLLTQGLKVRVLDMATIGFSLLRGDYVAA
ASISTMVVVGEFLRQATEDRSNGLLKSLVAAPVESVWVRRGDAEVAVAFADVVPGDLVLAGSGGLVAVDGLVVAGEALLD
CSSITGESAPVYVKEGAEILSGCVVREGAVTIEARRTGAETNMARISGFMENALREVSARERRSDRLADMLAPITLGLGA
VLYAATHDASRALSVLTIDYACAVKLPAPVVIKTSLHTAAREGVLIKSGSGLDAFAEADTLVFDKTGTLTTGRLRVTDVL
TAGIADDEFIRLAASVEDRSDHPVGQAVVAEAARRGLELLPAGNACCSIAHGIEAVVAGRVVRVGSHHYIAEDCGISCAA
LAGEAERLRSEAKTLVFVASGESLLGLIALRDEIRPEACDVLRQMRLRGIRHVYVLTGDHARTAETLLAQVPGIDGMHTD
LLPEEKAAFVKDLRSKGHKVAMIGDGVNDAPAFVAADVGVSLSRTQGLARESARIVLLRDSLHGLVVARDTGLRAAGILD
NCFMAGVGINTGLLLVAGAGLLSPVAAAAVHNATTFAILGGSAWAAGRRPAAGQQTDRRN
>Mature_699_residues
AQYPLPQLVHRTRGRLRYRWRRLSDPALDPEYFEAWLENTEGVARARVNPRAACVVIELAPQGSGADFGNVLLRVPARAF
SRGVPAPPRRGLGDAVFHAAMTAAVAAMPPGLQLPVAAAMGAPAVLKGAETLLTQGLKVRVLDMATIGFSLLRGDYVAAA
SISTMVVVGEFLRQATEDRSNGLLKSLVAAPVESVWVRRGDAEVAVAFADVVPGDLVLAGSGGLVAVDGLVVAGEALLDC
SSITGESAPVYVKEGAEILSGCVVREGAVTIEARRTGAETNMARISGFMENALREVSARERRSDRLADMLAPITLGLGAV
LYAATHDASRALSVLTIDYACAVKLPAPVVIKTSLHTAAREGVLIKSGSGLDAFAEADTLVFDKTGTLTTGRLRVTDVLT
AGIADDEFIRLAASVEDRSDHPVGQAVVAEAARRGLELLPAGNACCSIAHGIEAVVAGRVVRVGSHHYIAEDCGISCAAL
AGEAERLRSEAKTLVFVASGESLLGLIALRDEIRPEACDVLRQMRLRGIRHVYVLTGDHARTAETLLAQVPGIDGMHTDL
LPEEKAAFVKDLRSKGHKVAMIGDGVNDAPAFVAADVGVSLSRTQGLARESARIVLLRDSLHGLVVARDTGLRAAGILDN
CFMAGVGINTGLLLVAGAGLLSPVAAAAVHNATTFAILGGSAWAAGRRPAAGQQTDRRN

Specific function: Involved In Copper Efflux. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=484, Percent_Identity=28.9256198347107, Blast_Score=166, Evalue=7e-41,
Organism=Homo sapiens, GI55743073, Length=454, Percent_Identity=29.5154185022026, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI115529486, Length=512, Percent_Identity=25.1953125, Blast_Score=149, Evalue=7e-36,
Organism=Escherichia coli, GI1786691, Length=549, Percent_Identity=30.4189435336976, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1789879, Length=497, Percent_Identity=32.1931589537223, Blast_Score=185, Evalue=8e-48,
Organism=Escherichia coli, GI1786914, Length=505, Percent_Identity=27.9207920792079, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI2367363, Length=575, Percent_Identity=24, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17556548, Length=224, Percent_Identity=28.125, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320475, Length=486, Percent_Identity=28.3950617283951, Blast_Score=154, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6319772, Length=533, Percent_Identity=23.6397748592871, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325221, Length=552, Percent_Identity=23.731884057971, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321271, Length=168, Percent_Identity=32.1428571428571, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221329854, Length=260, Percent_Identity=30, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI161085803, Length=615, Percent_Identity=23.0894308943089, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 73148; Mature: 73017

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQYPLPQLVHRTRGRLRYRWRRLSDPALDPEYFEAWLENTEGVARARVNPRAACVVIEL
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCCEEEEEEEE
APQGSGADFGNVLLRVPARAFSRGVPAPPRRGLGDAVFHAAMTAAVAAMPPGLQLPVAAA
CCCCCCCCHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHH
MGAPAVLKGAETLLTQGLKVRVLDMATIGFSLLRGDYVAAASISTMVVVGEFLRQATEDR
CCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHH
SNGLLKSLVAAPVESVWVRRGDAEVAVAFADVVPGDLVLAGSGGLVAVDGLVVAGEALLD
CCHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCEEEECCEEEECHHHHH
CSSITGESAPVYVKEGAEILSGCVVREGAVTIEARRTGAETNMARISGFMENALREVSAR
HHHCCCCCCCEEEECCHHHHHHHHEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ERRSDRLADMLAPITLGLGAVLYAATHDASRALSVLTIDYACAVKLPAPVVIKTSLHTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEEEEEEEEEECCCCEEEEECHHHHH
REGVLIKSGSGLDAFAEADTLVFDKTGTLTTGRLRVTDVLTAGIADDEFIRLAASVEDRS
HCCEEEECCCCCCHHHCCCEEEEECCCCEEECCEEEEHHHHCCCCCHHHEEEEECCCCCC
DHPVGQAVVAEAARRGLELLPAGNACCSIAHGIEAVVAGRVVRVGSHHYIAEDCGISCAA
CCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCEEEECCCCEEHHHCCCCHHH
LAGEAERLRSEAKTLVFVASGESLLGLIALRDEIRPEACDVLRQMRLRGIRHVYVLTGDH
HCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCC
ARTAETLLAQVPGIDGMHTDLLPEEKAAFVKDLRSKGHKVAMIGDGVNDAPAFVAADVGV
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCC
SLSRTQGLARESARIVLLRDSLHGLVVARDTGLRAAGILDNCFMAGVGINTGLLLVAGAG
CHHHHHCHHHCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCC
LLSPVAAAAVHNATTFAILGGSAWAAGRRPAAGQQTDRRN
HHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AQYPLPQLVHRTRGRLRYRWRRLSDPALDPEYFEAWLENTEGVARARVNPRAACVVIEL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCCEEEEEEEE
APQGSGADFGNVLLRVPARAFSRGVPAPPRRGLGDAVFHAAMTAAVAAMPPGLQLPVAAA
CCCCCCCCHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHH
MGAPAVLKGAETLLTQGLKVRVLDMATIGFSLLRGDYVAAASISTMVVVGEFLRQATEDR
CCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHH
SNGLLKSLVAAPVESVWVRRGDAEVAVAFADVVPGDLVLAGSGGLVAVDGLVVAGEALLD
CCHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCEEEECCEEEECHHHHH
CSSITGESAPVYVKEGAEILSGCVVREGAVTIEARRTGAETNMARISGFMENALREVSAR
HHHCCCCCCCEEEECCHHHHHHHHEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ERRSDRLADMLAPITLGLGAVLYAATHDASRALSVLTIDYACAVKLPAPVVIKTSLHTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEEEEEEEEEECCCCEEEEECHHHHH
REGVLIKSGSGLDAFAEADTLVFDKTGTLTTGRLRVTDVLTAGIADDEFIRLAASVEDRS
HCCEEEECCCCCCHHHCCCEEEEECCCCEEECCEEEEHHHHCCCCCHHHEEEEECCCCCC
DHPVGQAVVAEAARRGLELLPAGNACCSIAHGIEAVVAGRVVRVGSHHYIAEDCGISCAA
CCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCEEEECCCCEEHHHCCCCHHH
LAGEAERLRSEAKTLVFVASGESLLGLIALRDEIRPEACDVLRQMRLRGIRHVYVLTGDH
HCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCC
ARTAETLLAQVPGIDGMHTDLLPEEKAAFVKDLRSKGHKVAMIGDGVNDAPAFVAADVGV
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCC
SLSRTQGLARESARIVLLRDSLHGLVVARDTGLRAAGILDNCFMAGVGINTGLLLVAGAG
CHHHHHCHHHCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCC
LLSPVAAAAVHNATTFAILGGSAWAAGRRPAAGQQTDRRN
HHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]