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The map label for this gene is fur [H]

Identifier: 78355544

GI number: 78355544

Start: 504399

End: 504671

Strand: Direct

Name: fur [H]

Synonym: Dde_0497

Alternate gene names: 78355544

Gene position: 504399-504671 (Clockwise)

Preceding gene: 78355543

Following gene: 78355545

Centisome position: 13.52

GC content: 55.68

Gene sequence:

>273_bases
GTGTACCGCACGCTTAAGCTGCTTGTGCGCTCGGGGCTGGCAGACTGCTTTGATATGGGCGAGGGGGTGACGCTGTACGA
ACATGCGTATGATCATCCCCATCATGATCATCTGATCTGCACACGCTGCGGCAGAAAAGAAGAAATTGTGGATGAGACCA
TAGAGCGCCGGCAGGTGGAACTGGCGGAGCGTTCCGGCTTTACACTGAGCCGCCACAGGATGTTTCTGTACGGACTTTGC
CCCGCATGCCGCCGTAAAGGTATAAAGGACTGA

Upstream 100 bases:

>100_bases
CAACCATAGTGGGAGCCTTTCTGGAGACGGAAGGACATTTTTCTTCTGAAGATCTGTACCACAAGGTCAGAAAGACCGAG
CCGGGAATAGGGCAGGCACA

Downstream 100 bases:

>100_bases
CCGTGGCACAGTATCCTTTGCCGCAGCTTGTACACCGCACCCGCGGCAGATTGCGCTACAGGTGGCGCAGGCTGTCCGAC
CCCGCGCTTGATCCGGAGTA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MYRTLKLLVRSGLADCFDMGEGVTLYEHAYDHPHHDHLICTRCGRKEEIVDETIERRQVELAERSGFTLSRHRMFLYGLC
PACRRKGIKD

Sequences:

>Translated_90_residues
MYRTLKLLVRSGLADCFDMGEGVTLYEHAYDHPHHDHLICTRCGRKEEIVDETIERRQVELAERSGFTLSRHRMFLYGLC
PACRRKGIKD
>Mature_90_residues
MYRTLKLLVRSGLADCFDMGEGVTLYEHAYDHPHHDHLICTRCGRKEEIVDETIERRQVELAERSGFTLSRHRMFLYGLC
PACRRKGIKD

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=81, Percent_Identity=38.2716049382716, Blast_Score=62, Evalue=9e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 10552; Mature: 10552

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRTLKLLVRSGLADCFDMGEGVTLYEHAYDHPHHDHLICTRCGRKEEIVDETIERRQVE
CCHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHH
LAERSGFTLSRHRMFLYGLCPACRRKGIKD
HHHHCCCCHHHHHHHHHHCCHHHHCCCCCC
>Mature Secondary Structure
MYRTLKLLVRSGLADCFDMGEGVTLYEHAYDHPHHDHLICTRCGRKEEIVDETIERRQVE
CCHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHH
LAERSGFTLSRHRMFLYGLCPACRRKGIKD
HHHHCCCCHHHHHHHHHHCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200525 [H]