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The map label for this gene is 78355522

Identifier: 78355522

GI number: 78355522

Start: 485013

End: 486389

Strand: Direct

Name: 78355522

Synonym: Dde_0475

Alternate gene names: NA

Gene position: 485013-486389 (Clockwise)

Preceding gene: 78355521

Following gene: 78355523

Centisome position: 13.0

GC content: 61.73

Gene sequence:

>1377_bases
ATGAATGGACAGCAGAATGTGATACGCATTGACAGCGATATATGCACGGGCTGCGGCCGGTGCAAAGATGTCTGCCCCGT
GGGGGCGGTGGAAGGGGTGCAGGGGACGCCGCACAGTATCAGAGAGGATGTCTGCGTATTGTGCGGGCAGTGCGTGCAGC
AGTGCAGTGCTTTTGCCTCTTTTTACGAACAGCACCCTGCCTGCATTGCCGAAAAGAAGCGGGAAAGAGGCCTTTTTGTT
TCGGAGGCAGCACCGCTTTTTGCCGCATGGCACACGGGGGATGCACCGCGGGTGGCCGGTCGTCTGGCAGAAGGCTGCCA
CAGCATGGTTCAGTGTGCGCCAGCCGTGCGTGCTGCCATCGGCGAAGAGTTCGGTATGCCTGCGGGGGCGCTGACCCCCG
GAAGGCTGGCCGCAGCATTGCGCAGGCTGGGATTCGACAGGGTTTACGACACCAATTTTGCAGCCGACCTGACCATAATG
GAAGAGGGCAGTGAGCTGCTGCAGCGTATGGAAGGCGCCGGACCGCTGCCCATGTTCACGTCGTGTTGCCCCGCATGGGT
CCGTTATGCCGAACAGCAGTTCCCCGACCTGCTGGAACATCTTTCATCCTGCAAGTCTCCGCAGCAGATGGCCGGAGCCG
TTTTCAAGTCGTACGGGGCGCAGCTGGACGGTGTGGACCCGCGGCAGGTTTTCAGCGTGGCGGTGATGCCCTGTACCTGC
AAAAAGGCAGAAGCGCAGAGACCCGGGATGGAGCATGACGGGGTGCGTGATGTGGATGCGGTGCTGACCACCGGCGAGCT
TGCGGCCATGCTGCGTCAGGCGCACATAGATTTTGCCGCTTTGCCCGACGAGCCGTTTGACCGGCCTCTGGGCAGCTACT
CAGGTGCCGGGAACATTTTCGGACTGACCGGCGGAGTGATGGAAGCCGCGCTGCGTACTGCCTATGAACTGGTGACCGGA
GAACCCGTGCCCTGCACGGAACTGGTGTATGTGCGGGGCGGCGAAGGAATCCGGCACGCAACCCTGACCATGGACGGCCG
CACCTTCCGCGTGGCTGTGGTGGCCGGATTGCAGCATGTGCGTCCGCTGCTGGAAGCCGTGCGCGCGGGTACCTGTGATG
TGAATTTTGTGGAGGTGATGTGCTGCCCGCAGGGCTGCATAAGCGGCGGGGGCCAGCCCAAAGTGCTGCTGCCTTTTCAG
CGGGATGAGGTGTATGCCGCGCGCAAGGCGGCGCTGTACCGCCACGATGCCGAGCTTGCCTGCCGCAAATCGCATGAAAA
TCCGCAGGTGCAGGCGTTGTACCGTGAATTTCTGGGCGAACCTCTGAGCCATGTTTCGCACAATCTGCTGCATACTGTTT
ACGGCCAGACGCGTTAG

Upstream 100 bases:

>100_bases
GCATGGCCGCGGTGAGTGATCTGCGCCGCAGACGCTGCGCGCAGGCTGCGGCCGGACTGGCAAAATACGTGACGGCATTG
CATCCGGAGGACGGAAGGTC

Downstream 100 bases:

>100_bases
GGAGGCTAAGATGAATGCTTTTATTGTGGCGGACCCGCGCCGGTGCATCGGGTGTGCCGCGTGCGAGGTGGCGTGTGCCG
CGGCAGCGGCAGGTCAGTCC

Product: ferredoxin hydrogenase

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNGQQNVIRIDSDICTGCGRCKDVCPVGAVEGVQGTPHSIREDVCVLCGQCVQQCSAFASFYEQHPACIAEKKRERGLFV
SEAAPLFAAWHTGDAPRVAGRLAEGCHSMVQCAPAVRAAIGEEFGMPAGALTPGRLAAALRRLGFDRVYDTNFAADLTIM
EEGSELLQRMEGAGPLPMFTSCCPAWVRYAEQQFPDLLEHLSSCKSPQQMAGAVFKSYGAQLDGVDPRQVFSVAVMPCTC
KKAEAQRPGMEHDGVRDVDAVLTTGELAAMLRQAHIDFAALPDEPFDRPLGSYSGAGNIFGLTGGVMEAALRTAYELVTG
EPVPCTELVYVRGGEGIRHATLTMDGRTFRVAVVAGLQHVRPLLEAVRAGTCDVNFVEVMCCPQGCISGGGQPKVLLPFQ
RDEVYAARKAALYRHDAELACRKSHENPQVQALYREFLGEPLSHVSHNLLHTVYGQTR

Sequences:

>Translated_458_residues
MNGQQNVIRIDSDICTGCGRCKDVCPVGAVEGVQGTPHSIREDVCVLCGQCVQQCSAFASFYEQHPACIAEKKRERGLFV
SEAAPLFAAWHTGDAPRVAGRLAEGCHSMVQCAPAVRAAIGEEFGMPAGALTPGRLAAALRRLGFDRVYDTNFAADLTIM
EEGSELLQRMEGAGPLPMFTSCCPAWVRYAEQQFPDLLEHLSSCKSPQQMAGAVFKSYGAQLDGVDPRQVFSVAVMPCTC
KKAEAQRPGMEHDGVRDVDAVLTTGELAAMLRQAHIDFAALPDEPFDRPLGSYSGAGNIFGLTGGVMEAALRTAYELVTG
EPVPCTELVYVRGGEGIRHATLTMDGRTFRVAVVAGLQHVRPLLEAVRAGTCDVNFVEVMCCPQGCISGGGQPKVLLPFQ
RDEVYAARKAALYRHDAELACRKSHENPQVQALYREFLGEPLSHVSHNLLHTVYGQTR
>Mature_458_residues
MNGQQNVIRIDSDICTGCGRCKDVCPVGAVEGVQGTPHSIREDVCVLCGQCVQQCSAFASFYEQHPACIAEKKRERGLFV
SEAAPLFAAWHTGDAPRVAGRLAEGCHSMVQCAPAVRAAIGEEFGMPAGALTPGRLAAALRRLGFDRVYDTNFAADLTIM
EEGSELLQRMEGAGPLPMFTSCCPAWVRYAEQQFPDLLEHLSSCKSPQQMAGAVFKSYGAQLDGVDPRQVFSVAVMPCTC
KKAEAQRPGMEHDGVRDVDAVLTTGELAAMLRQAHIDFAALPDEPFDRPLGSYSGAGNIFGLTGGVMEAALRTAYELVTG
EPVPCTELVYVRGGEGIRHATLTMDGRTFRVAVVAGLQHVRPLLEAVRAGTCDVNFVEVMCCPQGCISGGGQPKVLLPFQ
RDEVYAARKAALYRHDAELACRKSHENPQVQALYREFLGEPLSHVSHNLLHTVYGQTR

Specific function: Unknown

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=361, Percent_Identity=30.7479224376731, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI134284357, Length=386, Percent_Identity=29.0155440414508, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI6912524, Length=337, Percent_Identity=30.5637982195846, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI84452151, Length=337, Percent_Identity=30.5637982195846, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI14165461, Length=383, Percent_Identity=26.8929503916449, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71995015, Length=381, Percent_Identity=28.6089238845144, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324089, Length=269, Percent_Identity=25.2788104089219, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI116007464, Length=329, Percent_Identity=30.0911854103343, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI116007468, Length=329, Percent_Identity=30.0911854103343, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI116007470, Length=351, Percent_Identity=29.3447293447293, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI116007466, Length=351, Percent_Identity=29.3447293447293, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI116007462, Length=287, Percent_Identity=29.9651567944251, Blast_Score=118, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 49460; Mature: 49460

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGQQNVIRIDSDICTGCGRCKDVCPVGAVEGVQGTPHSIREDVCVLCGQCVQQCSAFAS
CCCCCCEEEECCHHHHCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FYEQHPACIAEKKRERGLFVSEAAPLFAAWHTGDAPRVAGRLAEGCHSMVQCAPAVRAAI
HHHHCCHHHHHHHHHCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GEEFGMPAGALTPGRLAAALRRLGFDRVYDTNFAADLTIMEEGSELLQRMEGAGPLPMFT
HHHHCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCHHH
SCCPAWVRYAEQQFPDLLEHLSSCKSPQQMAGAVFKSYGAQLDGVDPRQVFSVAVMPCTC
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
KKAEAQRPGMEHDGVRDVDAVLTTGELAAMLRQAHIDFAALPDEPFDRPLGSYSGAGNIF
CHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCEE
GLTGGVMEAALRTAYELVTGEPVPCTELVYVRGGEGIRHATLTMDGRTFRVAVVAGLQHV
ECHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCEEEHHHHHHHHHH
RPLLEAVRAGTCDVNFVEVMCCPQGCISGGGQPKVLLPFQRDEVYAARKAALYRHDAELA
HHHHHHHHCCCCCCEEEEEEECCHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCHHHH
CRKSHENPQVQALYREFLGEPLSHVSHNLLHTVYGQTR
HHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNGQQNVIRIDSDICTGCGRCKDVCPVGAVEGVQGTPHSIREDVCVLCGQCVQQCSAFAS
CCCCCCEEEECCHHHHCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FYEQHPACIAEKKRERGLFVSEAAPLFAAWHTGDAPRVAGRLAEGCHSMVQCAPAVRAAI
HHHHCCHHHHHHHHHCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GEEFGMPAGALTPGRLAAALRRLGFDRVYDTNFAADLTIMEEGSELLQRMEGAGPLPMFT
HHHHCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCHHH
SCCPAWVRYAEQQFPDLLEHLSSCKSPQQMAGAVFKSYGAQLDGVDPRQVFSVAVMPCTC
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
KKAEAQRPGMEHDGVRDVDAVLTTGELAAMLRQAHIDFAALPDEPFDRPLGSYSGAGNIF
CHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCEE
GLTGGVMEAALRTAYELVTGEPVPCTELVYVRGGEGIRHATLTMDGRTFRVAVVAGLQHV
ECHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCEEEHHHHHHHHHH
RPLLEAVRAGTCDVNFVEVMCCPQGCISGGGQPKVLLPFQRDEVYAARKAALYRHDAELA
HHHHHHHHCCCCCCEEEEEEECCHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCHHHH
CRKSHENPQVQALYREFLGEPLSHVSHNLLHTVYGQTR
HHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]