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The map label for this gene is tolQ [H]

Identifier: 78224720

GI number: 78224720

Start: 3971294

End: 3971968

Strand: Direct

Name: tolQ [H]

Synonym: Gmet_3537

Alternate gene names: 78224720

Gene position: 3971294-3971968 (Clockwise)

Preceding gene: 78224719

Following gene: 78224721

Centisome position: 99.35

GC content: 59.85

Gene sequence:

>675_bases
GTGTTACACCTTGCGGGAACCGGTCTTGTCGTAAAACTCGTTCTGCTCATTCTCATCTTCTTCTCGGTGGTCTCGTGGGC
AATCATCTTTTTCAAGCTCCTCCAGGTCTACCGGGCCAACAGCGAGTCGGAGCGTTTTCTGGACTTCTTCTGGAAGACCA
AGCGCTTCGATGCCGTCAACTCCCAACTGGACCGCTTCACCAACTCTCCCCTGACGGTCCTGTTCAGCGAGGGTTACAGT
GAACTGAAGCGCCTCGTGGAGAAGGGGGACCAGAAGGAGGAGCTGGATGTCATGAGCACCGAGCTGGGGGGCATCGAGAA
CATCGCCCGGGCCCTGCGCCGCGCCACCACCTCGGAAATCACCCGCTTGGAGAAGTATGTGACCTTCCTGGCCACCACCG
GCTCCACTACTCCCTTCATCGGCCTTTTCGGCACGGTCTGGGGGATCATGACCGCCTTCAAGGGGATCGGCGAGACCGGG
TCGGCATCCCTGGCCGTGGTGGCCCCGGGCATCTCCGAGGCCCTCATCGCCACCGCCATCGGCCTGGTGGCCGCCATCCC
GGCGGTCATGGCCTACAACCACTTCCAGTACAAGATCAAGGTTCTTATCGCCACCATGGACAACTTCTCCACCGAGTTCC
TGAATATCGTCCAGCGGACCGTGACCAAGAAGTAG

Upstream 100 bases:

>100_bases
CGATTTCGGTCGGCTTCAGGAAAACGGTTGACGCGACGGCGGGCCGGGACTATTGTTCAGCGATCACGTAACCCATTAAT
TATTAACGGAGGTTCATACC

Downstream 100 bases:

>100_bases
GAGCAGACCATGGAAATCGGCAGCAGAAACAACGGCGACCGCGGCACCATGTCGCAGATCAACGTCACCCCTATGGTGGA
CGTGATGCTCGTGCTCCTGG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MLHLAGTGLVVKLVLLILIFFSVVSWAIIFFKLLQVYRANSESERFLDFFWKTKRFDAVNSQLDRFTNSPLTVLFSEGYS
ELKRLVEKGDQKEELDVMSTELGGIENIARALRRATTSEITRLEKYVTFLATTGSTTPFIGLFGTVWGIMTAFKGIGETG
SASLAVVAPGISEALIATAIGLVAAIPAVMAYNHFQYKIKVLIATMDNFSTEFLNIVQRTVTKK

Sequences:

>Translated_224_residues
MLHLAGTGLVVKLVLLILIFFSVVSWAIIFFKLLQVYRANSESERFLDFFWKTKRFDAVNSQLDRFTNSPLTVLFSEGYS
ELKRLVEKGDQKEELDVMSTELGGIENIARALRRATTSEITRLEKYVTFLATTGSTTPFIGLFGTVWGIMTAFKGIGETG
SASLAVVAPGISEALIATAIGLVAAIPAVMAYNHFQYKIKVLIATMDNFSTEFLNIVQRTVTKK
>Mature_224_residues
MLHLAGTGLVVKLVLLILIFFSVVSWAIIFFKLLQVYRANSESERFLDFFWKTKRFDAVNSQLDRFTNSPLTVLFSEGYS
ELKRLVEKGDQKEELDVMSTELGGIENIARALRRATTSEITRLEKYVTFLATTGSTTPFIGLFGTVWGIMTAFKGIGETG
SASLAVVAPGISEALIATAIGLVAAIPAVMAYNHFQYKIKVLIATMDNFSTEFLNIVQRTVTKK

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=215, Percent_Identity=43.7209302325581, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789381, Length=214, Percent_Identity=37.3831775700935, Blast_Score=128, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 24835; Mature: 24835

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLAGTGLVVKLVLLILIFFSVVSWAIIFFKLLQVYRANSESERFLDFFWKTKRFDAVN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SQLDRFTNSPLTVLFSEGYSELKRLVEKGDQKEELDVMSTELGGIENIARALRRATTSEI
HHHHHHCCCCCEEHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TRLEKYVTFLATTGSTTPFIGLFGTVWGIMTAFKGIGETGSASLAVVAPGISEALIATAI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHH
GLVAAIPAVMAYNHFQYKIKVLIATMDNFSTEFLNIVQRTVTKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLHLAGTGLVVKLVLLILIFFSVVSWAIIFFKLLQVYRANSESERFLDFFWKTKRFDAVN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SQLDRFTNSPLTVLFSEGYSELKRLVEKGDQKEELDVMSTELGGIENIARALRRATTSEI
HHHHHHCCCCCEEHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TRLEKYVTFLATTGSTTPFIGLFGTVWGIMTAFKGIGETGSASLAVVAPGISEALIATAI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHH
GLVAAIPAVMAYNHFQYKIKVLIATMDNFSTEFLNIVQRTVTKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]