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The map label for this gene is trxB [H]

Identifier: 78224262

GI number: 78224262

Start: 3468586

End: 3469536

Strand: Reverse

Name: trxB [H]

Synonym: Gmet_3070

Alternate gene names: 78224262

Gene position: 3469536-3468586 (Counterclockwise)

Preceding gene: 78224265

Following gene: 78224261

Centisome position: 86.79

GC content: 62.78

Gene sequence:

>951_bases
ATGGAAACAACCCATCACCGCCTCATCATTCTCGGCTCCGGCCCTGCCGGCTACACCGCCGCCGTCTACGCCGCCCGCGC
CAACCTTAATCCGACCCTCATCACCGGACTCCAGCAGGGGGGGCAGTTGATGACCACCACCGAGGTGGACAACTGGCCCG
GCGATCCAAACGGCGTCCAGGGACCCGACCTCATGGAGCGGATGCGCCAGCACGCCGAGCGCTTCAATACCACCATGGTC
TTCGACCACATCGGTAAGGCGAATCTTCGCGAGCGACCCTTCCGCCTGGAGGGGGACAATGGCATCTATACCTGCGACGC
CCTCATCATTGCCACCGGTGCCACCGCCAGATACCTGGGGCTGCCGTCGGAGGACGCGTTCAAGGGGAAAGGGGTTTCGG
CCTGTGCCACCTGCGACGGTTTTTTTTATCGCGGCAAGCCGGTGGCGGTCATCGGCGGCGGCAGCACTGCCGTGGAAGAG
GCCCTCTACCTTTCCAACATCGCCAGTCATGTCACGGTCATTCACCGGCGCGACAAGTTCCGCTCCGAGAAGATTCTCGC
CGACCGTCTGATCGAAAAGACCAAGGGGGGTAATGTTACCATCGAATGGCACCATGTGCTGGACGAGGTTTTGGGGGACG
CCACCGGGGTCACCGGCATCCGCATCCGCCACACCAGCGGTTCCACCAAGGATATCCCGGTGCACGGCTGCTTCATTGCC
ATTGGCCATGCTCCCAACACCCAGCTCTTTGAGGGGCAACTGGAGATGGACAACGGCTACATCCGCACCCTCTGCGGCGG
CGAGGGGAACGTCACCGCCACCAGCATCCCCGGCGTCTTTGCCGCCGGCGACGTGCAGGACCAGTACTACAAGCAGGCCA
TAACCTCGGCTGGCACCGGCTGCATGGCGGCCCTGGACGCCGAGAAATATCTGGAGACTCTCTTGTCATGA

Upstream 100 bases:

>100_bases
AGATGCCCCTTTGGCGGGTCAAACGGAAAGAACCGCTCCCCCCTTGCATTTCCGGAGTGTTGCTGCTATCGTAGCGCGAC
TGTCTTTGGAGGATTCTAAT

Downstream 100 bases:

>100_bases
TCGGTCAGGTTCTTCTCACGGCCACTACCCTGTCTCCGGTCCACGGCCCCTGATGTTAGCCAAGGCCCTCTCCAGCGCTC
TCCTCGGGATCGACGCAGTC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
METTHHRLIILGSGPAGYTAAVYAARANLNPTLITGLQQGGQLMTTTEVDNWPGDPNGVQGPDLMERMRQHAERFNTTMV
FDHIGKANLRERPFRLEGDNGIYTCDALIIATGATARYLGLPSEDAFKGKGVSACATCDGFFYRGKPVAVIGGGSTAVEE
ALYLSNIASHVTVIHRRDKFRSEKILADRLIEKTKGGNVTIEWHHVLDEVLGDATGVTGIRIRHTSGSTKDIPVHGCFIA
IGHAPNTQLFEGQLEMDNGYIRTLCGGEGNVTATSIPGVFAAGDVQDQYYKQAITSAGTGCMAALDAEKYLETLLS

Sequences:

>Translated_316_residues
METTHHRLIILGSGPAGYTAAVYAARANLNPTLITGLQQGGQLMTTTEVDNWPGDPNGVQGPDLMERMRQHAERFNTTMV
FDHIGKANLRERPFRLEGDNGIYTCDALIIATGATARYLGLPSEDAFKGKGVSACATCDGFFYRGKPVAVIGGGSTAVEE
ALYLSNIASHVTVIHRRDKFRSEKILADRLIEKTKGGNVTIEWHHVLDEVLGDATGVTGIRIRHTSGSTKDIPVHGCFIA
IGHAPNTQLFEGQLEMDNGYIRTLCGGEGNVTATSIPGVFAAGDVQDQYYKQAITSAGTGCMAALDAEKYLETLLS
>Mature_316_residues
METTHHRLIILGSGPAGYTAAVYAARANLNPTLITGLQQGGQLMTTTEVDNWPGDPNGVQGPDLMERMRQHAERFNTTMV
FDHIGKANLRERPFRLEGDNGIYTCDALIIATGATARYLGLPSEDAFKGKGVSACATCDGFFYRGKPVAVIGGGSTAVEE
ALYLSNIASHVTVIHRRDKFRSEKILADRLIEKTKGGNVTIEWHHVLDEVLGDATGVTGIRIRHTSGSTKDIPVHGCFIA
IGHAPNTQLFEGQLEMDNGYIRTLCGGEGNVTATSIPGVFAAGDVQDQYYKQAITSAGTGCMAALDAEKYLETLLS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=314, Percent_Identity=69.4267515923567, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI87081763, Length=302, Percent_Identity=33.4437086092715, Blast_Score=147, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6321898, Length=320, Percent_Identity=45.3125, Blast_Score=281, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=45.5108359133127, Blast_Score=281, Evalue=1e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33943; Mature: 33943

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTHHRLIILGSGPAGYTAAVYAARANLNPTLITGLQQGGQLMTTTEVDNWPGDPNGVQ
CCCCCEEEEEEECCCCCCEEEEEEEECCCCHHEEEHHHCCCEEEEEEECCCCCCCCCCCC
GPDLMERMRQHAERFNTTMVFDHIGKANLRERPFRLEGDNGIYTCDALIIATGATARYLG
CHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEEECCCCEEEEC
LPSEDAFKGKGVSACATCDGFFYRGKPVAVIGGGSTAVEEALYLSNIASHVTVIHRRDKF
CCCCCCCCCCCCEEEEECCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHEEEHHHHHH
RSEKILADRLIEKTKGGNVTIEWHHVLDEVLGDATGVTGIRIRHTSGSTKDIPVHGCFIA
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEEE
IGHAPNTQLFEGQLEMDNGYIRTLCGGEGNVTATSIPGVFAAGDVQDQYYKQAITSAGTG
EECCCCCCEEECEEEECCCEEEEEECCCCCEEEEECCCEEEECCCHHHHHHHHHHHCCCC
CMAALDAEKYLETLLS
CEEHHCHHHHHHHHCC
>Mature Secondary Structure
METTHHRLIILGSGPAGYTAAVYAARANLNPTLITGLQQGGQLMTTTEVDNWPGDPNGVQ
CCCCCEEEEEEECCCCCCEEEEEEEECCCCHHEEEHHHCCCEEEEEEECCCCCCCCCCCC
GPDLMERMRQHAERFNTTMVFDHIGKANLRERPFRLEGDNGIYTCDALIIATGATARYLG
CHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEEECCCCEEEEC
LPSEDAFKGKGVSACATCDGFFYRGKPVAVIGGGSTAVEEALYLSNIASHVTVIHRRDKF
CCCCCCCCCCCCEEEEECCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHEEEHHHHHH
RSEKILADRLIEKTKGGNVTIEWHHVLDEVLGDATGVTGIRIRHTSGSTKDIPVHGCFIA
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEEE
IGHAPNTQLFEGQLEMDNGYIRTLCGGEGNVTATSIPGVFAAGDVQDQYYKQAITSAGTG
EECCCCCCEEECEEEECCCEEEEEECCCCCEEEEECCCEEEECCCHHHHHHHHHHHCCCC
CMAALDAEKYLETLLS
CEEHHCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]