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The map label for this gene is xerD [H]

Identifier: 78222639

GI number: 78222639

Start: 1597387

End: 1598274

Strand: Direct

Name: xerD [H]

Synonym: Gmet_1427

Alternate gene names: 78222639

Gene position: 1597387-1598274 (Clockwise)

Preceding gene: 78222638

Following gene: 78222640

Centisome position: 39.96

GC content: 59.12

Gene sequence:

>888_bases
GTGAACCAGTACCTCGATCTCTTTCTGAATTACCTTCTTGTGGAGAAGGGGCTGGCGAAAAATTCCCTCGATTCCTACGG
CCGCGACATGATCCGGTATCTGGATTTTCTTGAGAAACGGAATTGTGGTGAACCGTCTGCGGTGCGTCCCGTGGATGTGG
CGGATTTTCTGGCCCATCTCAAGGATTGTGGTCTCGCCCCCCGAAGCAGAGCCAGGGCCTTATCCGCCGTCCGGATGTTC
CACCGGTTTCTCCTGGTGGAGGGGTATGCCGAGGCGAACCCCACCGCGATCATCGAGGCGCCCAAGACGTTGGCCAAGCT
TCCCCAGATCCTCGCCGGCCGGGAGGTCGAGGCGCTTCTGGCTGCTCCCGGAAGTGACAGTGCCCAGGATATGCGGGACC
GGGCCATGCTGGAGCTTCTCTATGCCACGGGGCTGCGGGTCTCCGAACTTGTGGGCCTCGGTTTGCGCGATGTGAATGTA
ACCGCGGGATACCTCATGGCTTTCGGCAAGGGGGGGAAGGAGCGGCTCGTTCCCATGGGTGAATCCGCCTGTGCAGCAGT
TTCCCGTTATCTTGCCGAGGCGCGTCCCGAAATGGATCGAAACGGCGACAACGCCTATCTGTTTCTTACCCGGCTCGGAG
ACCGGATGACGCGGCAGGCGTTCTGGAATATAATCAAAAAACGGGCCATTGAGGCGGGAATCAGAAAAACCATTTCTCCC
CATACTCTGCGCCATTCGTTCGCAACCCATCTGCTGGAGAACGGCGCAGATCTGCGGAGCGTGCAGGCAATGCTCGGCCA
TGCGGACCTCGCGACGACACAGATTTACACCCACGTGACCCGGGAGCGATTGAAACGCATCCACGAGGAATACCATCCAC
GGGGATAG

Upstream 100 bases:

>100_bases
GTCTTCTACGTGAAGGACATATTCGGCCACAAGATCACCAATCCGGAGCGGCTCGAAGAAATACGGGAGAGACTTTTGAA
GGCCGTGGAGTGAGGAGAAC

Downstream 100 bases:

>100_bases
GGCGGGTCGGTGCAGACAGGAAAACTCACTCAGGAAAGGACAGGGCAATGAAGTATATCGTGCTCCTCGGCGACGGGATG
TCGGACGAGGCCGTGAAGGA

Product: tyrosine recombinase XerD subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNQYLDLFLNYLLVEKGLAKNSLDSYGRDMIRYLDFLEKRNCGEPSAVRPVDVADFLAHLKDCGLAPRSRARALSAVRMF
HRFLLVEGYAEANPTAIIEAPKTLAKLPQILAGREVEALLAAPGSDSAQDMRDRAMLELLYATGLRVSELVGLGLRDVNV
TAGYLMAFGKGGKERLVPMGESACAAVSRYLAEARPEMDRNGDNAYLFLTRLGDRMTRQAFWNIIKKRAIEAGIRKTISP
HTLRHSFATHLLENGADLRSVQAMLGHADLATTQIYTHVTRERLKRIHEEYHPRG

Sequences:

>Translated_295_residues
MNQYLDLFLNYLLVEKGLAKNSLDSYGRDMIRYLDFLEKRNCGEPSAVRPVDVADFLAHLKDCGLAPRSRARALSAVRMF
HRFLLVEGYAEANPTAIIEAPKTLAKLPQILAGREVEALLAAPGSDSAQDMRDRAMLELLYATGLRVSELVGLGLRDVNV
TAGYLMAFGKGGKERLVPMGESACAAVSRYLAEARPEMDRNGDNAYLFLTRLGDRMTRQAFWNIIKKRAIEAGIRKTISP
HTLRHSFATHLLENGADLRSVQAMLGHADLATTQIYTHVTRERLKRIHEEYHPRG
>Mature_295_residues
MNQYLDLFLNYLLVEKGLAKNSLDSYGRDMIRYLDFLEKRNCGEPSAVRPVDVADFLAHLKDCGLAPRSRARALSAVRMF
HRFLLVEGYAEANPTAIIEAPKTLAKLPQILAGREVEALLAAPGSDSAQDMRDRAMLELLYATGLRVSELVGLGLRDVNV
TAGYLMAFGKGGKERLVPMGESACAAVSRYLAEARPEMDRNGDNAYLFLTRLGDRMTRQAFWNIIKKRAIEAGIRKTISP
HTLRHSFATHLLENGADLRSVQAMLGHADLATTQIYTHVTRERLKRIHEEYHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=46.2328767123288, Blast_Score=254, Evalue=4e-69,
Organism=Escherichia coli, GI1790244, Length=287, Percent_Identity=36.9337979094077, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=33.9285714285714, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790767, Length=175, Percent_Identity=29.1428571428571, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32982; Mature: 32982

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQYLDLFLNYLLVEKGLAKNSLDSYGRDMIRYLDFLEKRNCGEPSAVRPVDVADFLAHL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
KDCGLAPRSRARALSAVRMFHRFLLVEGYAEANPTAIIEAPKTLAKLPQILAGREVEALL
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCCHHHHH
AAPGSDSAQDMRDRAMLELLYATGLRVSELVGLGLRDVNVTAGYLMAFGKGGKERLVPMG
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCC
ESACAAVSRYLAEARPEMDRNGDNAYLFLTRLGDRMTRQAFWNIIKKRAIEAGIRKTISP
HHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HTLRHSFATHLLENGADLRSVQAMLGHADLATTQIYTHVTRERLKRIHEEYHPRG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNQYLDLFLNYLLVEKGLAKNSLDSYGRDMIRYLDFLEKRNCGEPSAVRPVDVADFLAHL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
KDCGLAPRSRARALSAVRMFHRFLLVEGYAEANPTAIIEAPKTLAKLPQILAGREVEALL
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCCHHHHH
AAPGSDSAQDMRDRAMLELLYATGLRVSELVGLGLRDVNVTAGYLMAFGKGGKERLVPMG
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCC
ESACAAVSRYLAEARPEMDRNGDNAYLFLTRLGDRMTRQAFWNIIKKRAIEAGIRKTISP
HHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HTLRHSFATHLLENGADLRSVQAMLGHADLATTQIYTHVTRERLKRIHEEYHPRG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]