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The map label for this gene is yciR [C]

Identifier: 78067162

GI number: 78067162

Start: 2799251

End: 2801443

Strand: Direct

Name: yciR [C]

Synonym: Bcep18194_A5693

Alternate gene names: 78067162

Gene position: 2799251-2801443 (Clockwise)

Preceding gene: 78067161

Following gene: 78067163

Centisome position: 75.78

GC content: 65.44

Gene sequence:

>2193_bases
GTGGAAAAGGACAGCGCGTACAAGGAAGCCGCGGCTTCCGCCGCAATCCTGTCCTCCGCGCTCGAGCAGCATACGGTCAA
GGCGATCCACCAGGTCGACCAGATCACCCGCTTCGTCAAGTTCGAATTCGAGAAGTCGCCCGCGCGCTTCAATCTCGCCA
GCGCCGTCGAGAAAGGCGTCGTGCCGAGCGACACGCTGATCCAGGTATCGCTCGTCAACGCGAAGGGCATCCTGTTCGCG
AACACGGCCGAGCTGCATCCGCAGCCGATCAACCTGTCCGACCGCGAGCACTTCAAGGTCCACCTCGCGCACAACGACGA
CCGCCTGTTCATCAGCAAGCCCGTCCTCGGCCGCGTGTCGAGCCACTGGACGCTGCAGATGACGCGGCGCCTGAACAACC
CGGACGGCAGCTTCGCGGGCATCGTCGTCGTGTCGGAAGACCCGAGCTACTTCACGAACGACTTCTACAACAACGCGGCG
ATCGGCAAGGAAGGCGTGATCGCGGTCGTGTCCGATACGGGCGCCGTGCTCGCGCGGCGCACGGGCTCGGTCAGCAACGC
ACCCGGCGCGTTTTCCGCGTCGGGCGTCTACCCGATCGCCGAGCGCGTGACGGGCACGATCATCGACCCGATCGACGGCG
TGACGCGCATCGTGTCGTACCGCCACCTCGACGGCTACCCGCTCGCGGTGATGGTCGGGCTGTCGCAAACCGAGGAATTC
GCGGACTACTACCACACGCGCAACGTCTACCTGCTGATGACGAGCTTCATCACGCTCGCGATGCTCGCGTTCTTCGGCGT
CGCAACGGGCCTGATCGGCAAGCTGCTCGGCCGTGAGCGGGAAATGACGCAGCTCGCCGAATACGACCTGCTCACCGGCC
TCGCGAACCGCTATGCGACGCTGCGCGGGCTGCGCAACGACGTGTCGATGCCGGCGAGCCTGTCGCGGCTCGGGCTGCTG
TTCATCGATCTCGACAACTTCAAGACCGTCAACGACACGCTCGGCCACAACGCCGGCGACATCGTGCTGCAGATGACCGC
GTCGCGCCTGTCCGATGCGGTCGGCGACGAAGGCTCGCTTGCGCGCATCGGCGGCGACGAATTCGTCGTGGTGATGAAGG
GCGACGACGTCGAGCGGCGCGCGGTGCGGCTCGCGGAAGCGATCATCCGGATGTTCGGCGAACCGTTCGACGTGCGCGGC
AGCTCGTTCGTGCTGCATGCGAGCATCGGCATCGCGCTGCACTCGGTGGCGAACGAAAGCGAGATCGACCTGCTGAAGAA
AGCCGATCTCGCGATGTACAGCGCGAAGGATGCCGGCAAGAACTGCTACCAGTTCTATGCGCCGCACCTGTCGCACCGCG
CCGACCACCTGATGCGCTGGGAGCAGCAACTGCGCGTCGCGCTCGCCGAGGGGCAGCTGTTCCTCGCGTACCAGCCGAAA
ATCGACCTCACGCACCGCCATATCACCGGCTTCGAGGCGCTCGCGCGCTGGGATCACCCCGAGCATGGGATCATCTCCGC
GAACGAATTCATTTCGATTGCCGAATCAACGGGCCTGATCGTGCCGATCGGCGACTTCGTGATCCGCACCGCGTGCGAGC
AGATCGCGCGCTGGCGCGACGAGGGCCACGACACGCTGACGCTCGCGGTCAACATCTCGCCGGTGCAGTTCTGGCGCGGC
GACCTGATCGAGACGATCTCGCGCACGCTGCTGGAAACCGGCATCGACGCGAACCGGCTCGAAATCGAGATCACCGAAAC
CGCGATGATGGAATATCCGGAGCTCGTGTCCGAGAAGATCGTCGCGCTGAAGAAGCTCGGCATCCGGATCGCACTCGACG
ATTTCGGCACCGGCTATTCGTCGCTGTCGTACCTGCACCGCTTCTCCGTCGATACGCTGAAGGTCGACCGCTCGTTCGTG
CAGGCCATCCCGAACGATCGCAGCGTGTGCGTGATGGTGTCGTCGATCGTGCATCTCGCGCGCTCGCTCGGCCTGACCGT
CGTCGTCGAAGGCACGGAAACCGAGGAGCAGATCACGTGGCTGGCCGCGCTCGGCGAGATCGAGGCGCAAGGCTTCCTGT
TCTCGCGACCGGTGCCCGCCGACGCGATTCCCGCGCTGATCGCACGCTTCGGCGTGCGTGGCGACGCCCCGCACGTCATC
GCGCACCGCGCGACCGGCAGCACCGGCGCGTAA

Upstream 100 bases:

>100_bases
ACAGACGTCGGGACAACCCCAACCCTAGATAGCCATCCAGACGGATGGCGCACGCGAGCAGGACGCCGCCCTCTTCGATG
AGATCATCGCGCGGCTGTCG

Downstream 100 bases:

>100_bases
GCGCATCGCGGCCGTGGCGCGCGTTGCGCGCGCCGTCATTGTTTCGTTTTCCGATCCGATTGTTTAGTTCATGAACTAGC
GTTTTCGCGCATGGCAGTGT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MEKDSAYKEAAASAAILSSALEQHTVKAIHQVDQITRFVKFEFEKSPARFNLASAVEKGVVPSDTLIQVSLVNAKGILFA
NTAELHPQPINLSDREHFKVHLAHNDDRLFISKPVLGRVSSHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAA
IGKEGVIAVVSDTGAVLARRTGSVSNAPGAFSASGVYPIAERVTGTIIDPIDGVTRIVSYRHLDGYPLAVMVGLSQTEEF
ADYYHTRNVYLLMTSFITLAMLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPASLSRLGLL
FIDLDNFKTVNDTLGHNAGDIVLQMTASRLSDAVGDEGSLARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFGEPFDVRG
SSFVLHASIGIALHSVANESEIDLLKKADLAMYSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPK
IDLTHRHITGFEALARWDHPEHGIISANEFISIAESTGLIVPIGDFVIRTACEQIARWRDEGHDTLTLAVNISPVQFWRG
DLIETISRTLLETGIDANRLEIEITETAMMEYPELVSEKIVALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFV
QAIPNDRSVCVMVSSIVHLARSLGLTVVVEGTETEEQITWLAALGEIEAQGFLFSRPVPADAIPALIARFGVRGDAPHVI
AHRATGSTGA

Sequences:

>Translated_730_residues
MEKDSAYKEAAASAAILSSALEQHTVKAIHQVDQITRFVKFEFEKSPARFNLASAVEKGVVPSDTLIQVSLVNAKGILFA
NTAELHPQPINLSDREHFKVHLAHNDDRLFISKPVLGRVSSHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAA
IGKEGVIAVVSDTGAVLARRTGSVSNAPGAFSASGVYPIAERVTGTIIDPIDGVTRIVSYRHLDGYPLAVMVGLSQTEEF
ADYYHTRNVYLLMTSFITLAMLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPASLSRLGLL
FIDLDNFKTVNDTLGHNAGDIVLQMTASRLSDAVGDEGSLARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFGEPFDVRG
SSFVLHASIGIALHSVANESEIDLLKKADLAMYSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPK
IDLTHRHITGFEALARWDHPEHGIISANEFISIAESTGLIVPIGDFVIRTACEQIARWRDEGHDTLTLAVNISPVQFWRG
DLIETISRTLLETGIDANRLEIEITETAMMEYPELVSEKIVALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFV
QAIPNDRSVCVMVSSIVHLARSLGLTVVVEGTETEEQITWLAALGEIEAQGFLFSRPVPADAIPALIARFGVRGDAPHVI
AHRATGSTGA
>Mature_730_residues
MEKDSAYKEAAASAAILSSALEQHTVKAIHQVDQITRFVKFEFEKSPARFNLASAVEKGVVPSDTLIQVSLVNAKGILFA
NTAELHPQPINLSDREHFKVHLAHNDDRLFISKPVLGRVSSHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAA
IGKEGVIAVVSDTGAVLARRTGSVSNAPGAFSASGVYPIAERVTGTIIDPIDGVTRIVSYRHLDGYPLAVMVGLSQTEEF
ADYYHTRNVYLLMTSFITLAMLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPASLSRLGLL
FIDLDNFKTVNDTLGHNAGDIVLQMTASRLSDAVGDEGSLARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFGEPFDVRG
SSFVLHASIGIALHSVANESEIDLLKKADLAMYSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPK
IDLTHRHITGFEALARWDHPEHGIISANEFISIAESTGLIVPIGDFVIRTACEQIARWRDEGHDTLTLAVNISPVQFWRG
DLIETISRTLLETGIDANRLEIEITETAMMEYPELVSEKIVALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFV
QAIPNDRSVCVMVSSIVHLARSLGLTVVVEGTETEEQITWLAALGEIEAQGFLFSRPVPADAIPALIARFGVRGDAPHVI
AHRATGSTGA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=432, Percent_Identity=36.8055555555556, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI87081921, Length=429, Percent_Identity=33.5664335664336, Blast_Score=235, Evalue=6e-63,
Organism=Escherichia coli, GI226510982, Length=387, Percent_Identity=29.7157622739018, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1787055, Length=429, Percent_Identity=28.2051282051282, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1790496, Length=258, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1788502, Length=250, Percent_Identity=36.8, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=33.8912133891213, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI1786507, Length=214, Percent_Identity=35.5140186915888, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=33.4710743801653, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081980, Length=252, Percent_Identity=31.7460317460317, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788849, Length=243, Percent_Identity=31.6872427983539, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87082096, Length=237, Percent_Identity=30.8016877637131, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=35.9756097560976, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788381, Length=200, Percent_Identity=34, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786584, Length=198, Percent_Identity=31.3131313131313, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081977, Length=201, Percent_Identity=31.8407960199005, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082007, Length=195, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=29.585798816568, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=33.1325301204819, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI87081881, Length=170, Percent_Identity=34.1176470588235, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1787262, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1787410, Length=235, Percent_Identity=22.1276595744681, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 80062; Mature: 80062

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDSAYKEAAASAAILSSALEQHTVKAIHQVDQITRFVKFEFEKSPARFNLASAVEKGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHCC
VPSDTLIQVSLVNAKGILFANTAELHPQPINLSDREHFKVHLAHNDDRLFISKPVLGRVS
CCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCHHCCC
SHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARR
CCEEEEEEHHCCCCCCCEEEEEEEECCCCHHHHHCCCCCCCCCCCEEEEEECCCCEEEEC
TGSVSNAPGAFSASGVYPIAERVTGTIIDPIDGVTRIVSYRHLDGYPLAVMVGLSQTEEF
CCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHH
ADYYHTRNVYLLMTSFITLAMLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYAT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LRGLRNDVSMPASLSRLGLLFIDLDNFKTVNDTLGHNAGDIVLQMTASRLSDAVGDEGSL
HHHHHHCCCCCCCHHHCEEEEEECCCCEECHHHHCCCCCCEEEEEEHHHHHHHCCCCCCE
ARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFGEPFDVRGSSFVLHASIGIALHSVANES
EEECCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCC
EIDLLKKADLAMYSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPK
HHHHHHHHHHHHEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
IDLTHRHITGFEALARWDHPEHGIISANEFISIAESTGLIVPIGDFVIRTACEQIARWRD
CCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHEECCCCCEEEEHHHHHHHHHHHHHHHHHH
EGHDTLTLAVNISPVQFWRGDLIETISRTLLETGIDANRLEIEITETAMMEYPELVSEKI
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHH
VALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPNDRSVCVMVSSIVHLA
HHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RSLGLTVVVEGTETEEQITWLAALGEIEAQGFLFSRPVPADAIPALIARFGVRGDAPHVI
HHCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCEE
AHRATGSTGA
EEECCCCCCC
>Mature Secondary Structure
MEKDSAYKEAAASAAILSSALEQHTVKAIHQVDQITRFVKFEFEKSPARFNLASAVEKGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHCC
VPSDTLIQVSLVNAKGILFANTAELHPQPINLSDREHFKVHLAHNDDRLFISKPVLGRVS
CCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCHHCCC
SHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARR
CCEEEEEEHHCCCCCCCEEEEEEEECCCCHHHHHCCCCCCCCCCCEEEEEECCCCEEEEC
TGSVSNAPGAFSASGVYPIAERVTGTIIDPIDGVTRIVSYRHLDGYPLAVMVGLSQTEEF
CCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHH
ADYYHTRNVYLLMTSFITLAMLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYAT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LRGLRNDVSMPASLSRLGLLFIDLDNFKTVNDTLGHNAGDIVLQMTASRLSDAVGDEGSL
HHHHHHCCCCCCCHHHCEEEEEECCCCEECHHHHCCCCCCEEEEEEHHHHHHHCCCCCCE
ARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFGEPFDVRGSSFVLHASIGIALHSVANES
EEECCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCC
EIDLLKKADLAMYSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPK
HHHHHHHHHHHHEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
IDLTHRHITGFEALARWDHPEHGIISANEFISIAESTGLIVPIGDFVIRTACEQIARWRD
CCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHEECCCCCEEEEHHHHHHHHHHHHHHHHHH
EGHDTLTLAVNISPVQFWRGDLIETISRTLLETGIDANRLEIEITETAMMEYPELVSEKI
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHH
VALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPNDRSVCVMVSSIVHLA
HHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RSLGLTVVVEGTETEEQITWLAALGEIEAQGFLFSRPVPADAIPALIARFGVRGDAPHVI
HHCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCEE
AHRATGSTGA
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]