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The map label for this gene is yfcG [H]

Identifier: 78067025

GI number: 78067025

Start: 2654261

End: 2654953

Strand: Direct

Name: yfcG [H]

Synonym: Bcep18194_A5556

Alternate gene names: 78067025

Gene position: 2654261-2654953 (Clockwise)

Preceding gene: 78067024

Following gene: 78067053

Centisome position: 71.85

GC content: 63.35

Gene sequence:

>693_bases
ATGATCGACGTCTACAGTTGGGCGACCCCGAACGGCCACAAGGTGCACATCATGCTCGAGGAAACGGGCCTCGCTTATCG
TGTCCATCCGGTCGATATCGGCGCGGGCGACCAGTTCAAGCCGGAATTCCTGACGATCAGCCCGAACAACAAGATCCCCG
CGATCGTCGATCCGGACGGCCCCGGCGGCCAGCCGATCTCGCTGTTCGAATCCGGCGCGATCCTGATCTACCTCGCGGAG
AAGACCGGCAAGTTCCTGCCGACCGATCCGGCCGCACGCTACGCGACGCTCGAATGGCTGATGTTCCAGATGGGCGGGGT
CGGCCCGATGCTCGGGCAGGCGCATCACTTCCGCCTGTATGCGCCGGAGAAGATCGAATATGCGGTCAACCGCTACACGA
ACGAGGCGAGGCGCCTGTACAACGTGATGGACAAACGTCTCGGCGAATCCGAGTATCTCGCGGGCGATGCGTACACGATC
GCGGACATTGCGACGTTCCCGTGGACACGCTCGTGGCAGAACCAGGGCATCGTGCTCGACGAATTGCCGAACGTGAAGCG
CTGGTACGACGCGATCGCTGCACGACCGGCCGTGCAGCGCGGTGTCGAAGTGCTCGCATCGATGCGCAAGGCGCTGCAGG
ACGACAAGGCGCGCGAGGTGCTGTTCGGCGCGACGCAATACGCGAAGCACTGA

Upstream 100 bases:

>100_bases
ACATTTCCGTCGCCAGCAGCCCATATCGATCCATGCTCTAATGACCGCCTGTCGCGGCGCTGCCGGCGCCGTTTTCGCGC
ATGCCACAAAGGAGTTCACA

Downstream 100 bases:

>100_bases
CGCGCATGTGAAAAGCGGAGCGGCATCCGTGCATGCCGCTCCCCGCTTCAGAAGTAATGCAGCGTGATGAATTCCGCCGC
GCAAACAGGCAGCGGCGCAT

Product: glutathione S-transferase-like protein

Products: HX; R-S-glutathione

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIDVYSWATPNGHKVHIMLEETGLAYRVHPVDIGAGDQFKPEFLTISPNNKIPAIVDPDGPGGQPISLFESGAILIYLAE
KTGKFLPTDPAARYATLEWLMFQMGGVGPMLGQAHHFRLYAPEKIEYAVNRYTNEARRLYNVMDKRLGESEYLAGDAYTI
ADIATFPWTRSWQNQGIVLDELPNVKRWYDAIAARPAVQRGVEVLASMRKALQDDKAREVLFGATQYAKH

Sequences:

>Translated_230_residues
MIDVYSWATPNGHKVHIMLEETGLAYRVHPVDIGAGDQFKPEFLTISPNNKIPAIVDPDGPGGQPISLFESGAILIYLAE
KTGKFLPTDPAARYATLEWLMFQMGGVGPMLGQAHHFRLYAPEKIEYAVNRYTNEARRLYNVMDKRLGESEYLAGDAYTI
ADIATFPWTRSWQNQGIVLDELPNVKRWYDAIAARPAVQRGVEVLASMRKALQDDKAREVLFGATQYAKH
>Mature_230_residues
MIDVYSWATPNGHKVHIMLEETGLAYRVHPVDIGAGDQFKPEFLTISPNNKIPAIVDPDGPGGQPISLFESGAILIYLAE
KTGKFLPTDPAARYATLEWLMFQMGGVGPMLGQAHHFRLYAPEKIEYAVNRYTNEARRLYNVMDKRLGESEYLAGDAYTI
ADIATFPWTRSWQNQGIVLDELPNVKRWYDAIAARPAVQRGVEVLASMRKALQDDKAREVLFGATQYAKH

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=218, Percent_Identity=54.1284403669725, Blast_Score=234, Evalue=5e-63,
Organism=Escherichia coli, GI87082195, Length=214, Percent_Identity=47.6635514018692, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI87081789, Length=187, Percent_Identity=30.4812834224599, Blast_Score=74, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324100, Length=234, Percent_Identity=35.042735042735, Blast_Score=129, Evalue=3e-31,
Organism=Drosophila melanogaster, GI17864592, Length=223, Percent_Identity=31.390134529148, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17933730, Length=222, Percent_Identity=27.4774774774775, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17864598, Length=204, Percent_Identity=29.9019607843137, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571670, Length=173, Percent_Identity=28.3236994219653, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17864594, Length=221, Percent_Identity=28.5067873303167, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI85725204, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17737923, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45549270, Length=192, Percent_Identity=28.125, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922160, Length=215, Percent_Identity=25.1162790697674, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646251, Length=175, Percent_Identity=30.2857142857143, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864596, Length=219, Percent_Identity=24.6575342465753, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 25812; Mature: 25812

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDVYSWATPNGHKVHIMLEETGLAYRVHPVDIGAGDQFKPEFLTISPNNKIPAIVDPDG
CCCEEECCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCCCEEEECCCCCCCEEECCCC
PGGQPISLFESGAILIYLAEKTGKFLPTDPAARYATLEWLMFQMGGVGPMLGQAHHFRLY
CCCCCEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCEEEEE
APEKIEYAVNRYTNEARRLYNVMDKRLGESEYLAGDAYTIADIATFPWTRSWQNQGIVLD
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEHHEECCCCCCCCCCCEEHH
ELPNVKRWYDAIAARPAVQRGVEVLASMRKALQDDKAREVLFGATQYAKH
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDVYSWATPNGHKVHIMLEETGLAYRVHPVDIGAGDQFKPEFLTISPNNKIPAIVDPDG
CCCEEECCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCCCEEEECCCCCCCEEECCCC
PGGQPISLFESGAILIYLAEKTGKFLPTDPAARYATLEWLMFQMGGVGPMLGQAHHFRLY
CCCCCEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCEEEEE
APEKIEYAVNRYTNEARRLYNVMDKRLGESEYLAGDAYTIADIATFPWTRSWQNQGIVLD
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEHHEECCCCCCCCCCCEEHH
ELPNVKRWYDAIAARPAVQRGVEVLASMRKALQDDKAREVLFGATQYAKH
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]