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The map label for this gene is hipO [H]

Identifier: 78065858

GI number: 78065858

Start: 1345097

End: 1346317

Strand: Reverse

Name: hipO [H]

Synonym: Bcep18194_A4387

Alternate gene names: 78065858

Gene position: 1346317-1345097 (Counterclockwise)

Preceding gene: 78065860

Following gene: 78065857

Centisome position: 36.44

GC content: 68.47

Gene sequence:

>1221_bases
ATGCCCATTTCTCCACCGATCCAGGCGCTGGCAGCCGACATGCGCGACTGGCGCCGGCTCATTCACAGCAAACCGGAAAT
CGCATTCCAGGAACGCGGCACGGCCGACTTCATCGCGACGCGGTTGCGCGAATTCGGCATCGACGTTCATACCGGCGTCG
GCCAGACCGGCGTGGTCGGCATCGTCGACGGAACGCTCGGCGCCGGCCGCACCGTCGCCTTGCGCGCCGACATGGATGCG
CTGCCGATGCGGGAACTGGGCCGCCCGGTCTACCGGTCGGTGTTCGAAGGCATCTTTCACGGCTGCGGCCACGATGGCCA
CGTCGCGATCCTGCTCGGCACCGCACGCCATCTCGCCGAGCATCGCCACTTCCGCGGCCGCGTCGTGCTGATCTTCCAGC
CGGCCGAGGAAATCGTCTGCGGCAGCCGCGCGATGCTCGACGACGGGTTGCTCGAGCGCTTCCCGTTCGACGAAATCTAC
AGCCTCCACAACGACCCGATGCTGCCGCCGTCGAGGATCGGCGTGCGCGCCGGCGCGCAACAGGCATCGTCCGACCGGTT
TCAGATCCGGATCCACGGCATCGGCACCCACGCCGGCATGCCGCACCTCGGCATCGATCCGGTCGCGATCGGCGCGCACC
TGGTTGCGATGCTGCAAACCGTCGCGAGCCGGTCGGTCGATCCGCTGGAAAGCGTCGTGATCTCGATCGCGCGCTTTCAC
GCCGGCGACGCATTCAACGTGATTCCGCACGAAGCCGTGCTCGGCGGCACCGTGCGCGCGCTGTCGAACGACACGCGCAC
CTTCGCGCTCGAGCGGATGCGTGCGATCTGCGACGGCGTCGCGCTCGCCAATCGCACGCGCATCGAATTCGAATTGCTGG
ACGGCACGCCGGCGATCGTCAACCACGCCGACGCGGTGCAGTGCGTGATGGACGCCGCGCGCGAGGTCGTCGGGGCGGAA
AACGTGATCGGCAACGTCACGCCGCTGATGGCCGGCGACGACATCGCGAACTTCCTCGATGCACGCCCCGGCTGCCACTT
TCTGCTCGGCCAGGGCGGCCACATGTGCCATCACCCCGAATACGACTTCAACGACGACGTCGCGCCGATCGGCGTCGCGA
TGTTCGCATCGATCCTGCGCGCGCGGCTGGGCGCCGGCGCCGAACCGATACCGACCGGCCTCGACGAACGCAGTGCGCTG
GCGGCGGCCGCCGCGCGCTGA

Upstream 100 bases:

>100_bases
GCGAATTTCTCCACATAGCATCGGTTTCAAGGGAACCCCGTTTCCCGCCCCGAAGCAGCAGCGTGCTTCGCTACCCATTT
TGCAAAGGCGACACCCGATC

Downstream 100 bases:

>100_bases
CGAGCACCGCCCGAACCCTCATCGCCCCATCCGGCGTTCCACGCCGCACATAACGACACGACGGATCATCCGTCCACGGA
GACAGCGTCATGAGCACCAC

Product: peptidase M20D, amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MPISPPIQALAADMRDWRRLIHSKPEIAFQERGTADFIATRLREFGIDVHTGVGQTGVVGIVDGTLGAGRTVALRADMDA
LPMRELGRPVYRSVFEGIFHGCGHDGHVAILLGTARHLAEHRHFRGRVVLIFQPAEEIVCGSRAMLDDGLLERFPFDEIY
SLHNDPMLPPSRIGVRAGAQQASSDRFQIRIHGIGTHAGMPHLGIDPVAIGAHLVAMLQTVASRSVDPLESVVISIARFH
AGDAFNVIPHEAVLGGTVRALSNDTRTFALERMRAICDGVALANRTRIEFELLDGTPAIVNHADAVQCVMDAAREVVGAE
NVIGNVTPLMAGDDIANFLDARPGCHFLLGQGGHMCHHPEYDFNDDVAPIGVAMFASILRARLGAGAEPIPTGLDERSAL
AAAAAR

Sequences:

>Translated_406_residues
MPISPPIQALAADMRDWRRLIHSKPEIAFQERGTADFIATRLREFGIDVHTGVGQTGVVGIVDGTLGAGRTVALRADMDA
LPMRELGRPVYRSVFEGIFHGCGHDGHVAILLGTARHLAEHRHFRGRVVLIFQPAEEIVCGSRAMLDDGLLERFPFDEIY
SLHNDPMLPPSRIGVRAGAQQASSDRFQIRIHGIGTHAGMPHLGIDPVAIGAHLVAMLQTVASRSVDPLESVVISIARFH
AGDAFNVIPHEAVLGGTVRALSNDTRTFALERMRAICDGVALANRTRIEFELLDGTPAIVNHADAVQCVMDAAREVVGAE
NVIGNVTPLMAGDDIANFLDARPGCHFLLGQGGHMCHHPEYDFNDDVAPIGVAMFASILRARLGAGAEPIPTGLDERSAL
AAAAAR
>Mature_405_residues
PISPPIQALAADMRDWRRLIHSKPEIAFQERGTADFIATRLREFGIDVHTGVGQTGVVGIVDGTLGAGRTVALRADMDAL
PMRELGRPVYRSVFEGIFHGCGHDGHVAILLGTARHLAEHRHFRGRVVLIFQPAEEIVCGSRAMLDDGLLERFPFDEIYS
LHNDPMLPPSRIGVRAGAQQASSDRFQIRIHGIGTHAGMPHLGIDPVAIGAHLVAMLQTVASRSVDPLESVVISIARFHA
GDAFNVIPHEAVLGGTVRALSNDTRTFALERMRAICDGVALANRTRIEFELLDGTPAIVNHADAVQCVMDAAREVVGAEN
VIGNVTPLMAGDDIANFLDARPGCHFLLGQGGHMCHHPEYDFNDDVAPIGVAMFASILRARLGAGAEPIPTGLDERSALA
AAAAR

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=427, Percent_Identity=26.463700234192, Blast_Score=92, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 43587; Mature: 43455

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISPPIQALAADMRDWRRLIHSKPEIAFQERGTADFIATRLREFGIDVHTGVGQTGVVG
CCCCHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCHHHHHHHHHHHCCEEECCCCCCCEEE
IVDGTLGAGRTVALRADMDALPMRELGRPVYRSVFEGIFHGCGHDGHVAILLGTARHLAE
EEECCCCCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHH
HRHFRGRVVLIFQPAEEIVCGSRAMLDDGLLERFPFDEIYSLHNDPMLPPSRIGVRAGAQ
HHHCCCEEEEEECCHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHCHHCCCC
QASSDRFQIRIHGIGTHAGMPHLGIDPVAIGAHLVAMLQTVASRSVDPLESVVISIARFH
CCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
AGDAFNVIPHEAVLGGTVRALSNDTRTFALERMRAICDGVALANRTRIEFELLDGTPAIV
CCCCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHH
NHADAVQCVMDAAREVVGAENVIGNVTPLMAGDDIANFLDARPGCHFLLGQGGHMCHHPE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCC
YDFNDDVAPIGVAMFASILRARLGAGAEPIPTGLDERSALAAAAAR
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
PISPPIQALAADMRDWRRLIHSKPEIAFQERGTADFIATRLREFGIDVHTGVGQTGVVG
CCCHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCHHHHHHHHHHHCCEEECCCCCCCEEE
IVDGTLGAGRTVALRADMDALPMRELGRPVYRSVFEGIFHGCGHDGHVAILLGTARHLAE
EEECCCCCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHH
HRHFRGRVVLIFQPAEEIVCGSRAMLDDGLLERFPFDEIYSLHNDPMLPPSRIGVRAGAQ
HHHCCCEEEEEECCHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHCHHCCCC
QASSDRFQIRIHGIGTHAGMPHLGIDPVAIGAHLVAMLQTVASRSVDPLESVVISIARFH
CCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
AGDAFNVIPHEAVLGGTVRALSNDTRTFALERMRAICDGVALANRTRIEFELLDGTPAIV
CCCCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHH
NHADAVQCVMDAAREVVGAENVIGNVTPLMAGDDIANFLDARPGCHFLLGQGGHMCHHPE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCC
YDFNDDVAPIGVAMFASILRARLGAGAEPIPTGLDERSALAAAAAR
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]