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The map label for this gene is pdxY [H]

Identifier: 78065751

GI number: 78065751

Start: 1215809

End: 1216699

Strand: Reverse

Name: pdxY [H]

Synonym: Bcep18194_A4279

Alternate gene names: 78065751

Gene position: 1216699-1215809 (Counterclockwise)

Preceding gene: 78065753

Following gene: 78065750

Centisome position: 32.94

GC content: 67.34

Gene sequence:

>891_bases
GTGACCCTGAAACGCGTGCAGGCGATTCCCATGAAAAACGTCCTCAGCATTCAGTCGCACGTCATCTACGGCCATGCCGG
CAACAGTGCGGCCGTATTCCCGATGCAGCGCCTCGGCATCAACGTCTGGCCGCTCAATACCGTCCAGTTGTCGAATCACA
TGCAGTACGGTCACTGGGCCGGCAGCGCGATCGATGCCGCGAAGATGGAACAGCTCGTCGACGGCATCGCCGCGATCGGC
GCACTCAAGCGCTGCGACGCCGTGCTGTCCGGCTTCCTCGGCTCGCCGCCGCAAGCGCGTGCGGCCGTCGAGATCGTCCG
CTCGGTGAAGGCGATGAACCCGAACGCGTGGTACTTCTGCGATCCGGCGATGGGGCAGACGGGCGGCATCCGGCCCGAGC
CCGGCGTCGAGGAATTCATGGTCCAGGAGATGCCGGCGCTCGCAGACGGCATGTCGCCGAACCACACCGAACTGCAGAAG
CTCGCCGGGCGGCGCATCGAAACCGTCGCCGAAGCCGTCGAAGCCTGCCGCGCGCTGATCCGTCGCGGCCCGCAGATCAT
CCTCGTCAAGCACCTGCACGACCGCAACAGCCCGGCCGATCGTTTCAACATGCTCGCCGTCACCGAAACCGAAGCGTGGA
TCGGCCAGCGCCCGCTGTACGCGTTTCCGCGCCATCCGGTCGGCGTCGGCGACCTGACCAGTGCGATCTTCGTCGCCTGC
CGGCTGCGCGGCGACTCCGTGCGCGCGGCGTTCGAGCACACGCTCGCGGCCGTGCATGCGGTCGTGAAGGCCACCTACGA
TGCGCGCCGCTACGAGCTCGAACTCGTCGCCGCGCAGGACGAAATCGCGCGCCCGAGCGAATGGTTCGGCGCGTGGGTCA
CGGACGCCTGA

Upstream 100 bases:

>100_bases
CTCGCGCCCCGCGATTCTACGCGGTCGCGCTGACGACGGCGCGCAACACTCCGGGGCCGCGCGACTTCCGCGCGCGCGAC
GAACTCGGGTATCGTGTGAC

Downstream 100 bases:

>100_bases
CACGCCGGCGTCGCCCTCCGCTTCCCCGGCGCACCTCCCGCGCCGCACCGCTTTCCCGCCTCATCCCTGCCGCACCGCGA
CTGCCGGCGATAGTTGTCCC

Product: pyridoxal kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTLKRVQAIPMKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIG
ALKRCDAVLSGFLGSPPQARAAVEIVRSVKAMNPNAWYFCDPAMGQTGGIRPEPGVEEFMVQEMPALADGMSPNHTELQK
LAGRRIETVAEAVEACRALIRRGPQIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVAC
RLRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA

Sequences:

>Translated_296_residues
MTLKRVQAIPMKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIG
ALKRCDAVLSGFLGSPPQARAAVEIVRSVKAMNPNAWYFCDPAMGQTGGIRPEPGVEEFMVQEMPALADGMSPNHTELQK
LAGRRIETVAEAVEACRALIRRGPQIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVAC
RLRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA
>Mature_295_residues
TLKRVQAIPMKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGA
LKRCDAVLSGFLGSPPQARAAVEIVRSVKAMNPNAWYFCDPAMGQTGGIRPEPGVEEFMVQEMPALADGMSPNHTELQKL
AGRRIETVAEAVEACRALIRRGPQIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVACR
LRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=268, Percent_Identity=31.7164179104478, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1787924, Length=283, Percent_Identity=53.0035335689046, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI1788758, Length=264, Percent_Identity=25.3787878787879, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17507759, Length=260, Percent_Identity=30, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17507757, Length=270, Percent_Identity=28.8888888888889, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6324354, Length=273, Percent_Identity=32.2344322344322, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320806, Length=271, Percent_Identity=30.2583025830258, Blast_Score=93, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45553007, Length=292, Percent_Identity=29.4520547945205, Blast_Score=132, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 32382; Mature: 32250

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKRVQAIPMKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWA
CCCHHHHHCCHHHHHHHHHEEEEEECCCCEEECCHHHHCEEECCCCEEECCCCCCCCCCC
GSAIDAAKMEQLVDGIAAIGALKRCDAVLSGFLGSPPQARAAVEIVRSVKAMNPNAWYFC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEE
DPAMGQTGGIRPEPGVEEFMVQEMPALADGMSPNHTELQKLAGRRIETVAEAVEACRALI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHH
RRGPQIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVAC
HCCCCEEEEEECCCCCCCHHHHEEEEEECCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
RLRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA
HCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEEECCHHHCCCHHHHCEECCCC
>Mature Secondary Structure 
TLKRVQAIPMKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWA
CCHHHHHCCHHHHHHHHHEEEEEECCCCEEECCHHHHCEEECCCCEEECCCCCCCCCCC
GSAIDAAKMEQLVDGIAAIGALKRCDAVLSGFLGSPPQARAAVEIVRSVKAMNPNAWYFC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEE
DPAMGQTGGIRPEPGVEEFMVQEMPALADGMSPNHTELQKLAGRRIETVAEAVEACRALI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHH
RRGPQIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVAC
HCCCCEEEEEECCCCCCCHHHHEEEEEECCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
RLRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA
HCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEEECCHHHCCCHHHHCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA