Click here to switch to the map view.

The map label for this gene is gph [C]

Identifier: 78065622

GI number: 78065622

Start: 1084034

End: 1084750

Strand: Reverse

Name: gph [C]

Synonym: Bcep18194_A4150

Alternate gene names: 78065622

Gene position: 1084750-1084034 (Counterclockwise)

Preceding gene: 78065623

Following gene: 78065618

Centisome position: 29.36

GC content: 70.57

Gene sequence:

>717_bases
ATGACGACTCCCCTCTCGACCGCGCGGGCTGCACTCGACGAACCGCGCCTGCTGCACTGCGATGCCGTGCTGTTCGATCT
GGACGGCACGCTCGCCGACACGGCCCCCGATCTCGCGGCTGCCGTCAACAAGATGCAACGCGTGCGCGACCTGCCCGAAA
CGCCGCTCGACGTGTTGCGGCCGCTGGCCTCGGCCGGCGCACGCGGCCTGCTCGGCGGCGCGTTCGGCATCGATCCGCAG
ACGCCCGGCTATGAAGCGATGCGCGACGAATTCCTGGCCAACTACGCGACGGATCTGTGCGTGCACACGACGCTGTTCCC
CGGCATCGGCGACGTGCTCGACGAACTCGATGCGCGCGGCGTGCGCTGGGGCATCGTCACGAACAAGGCGATGCGGCTCA
CGGCGCCGCTCGTCGACCTGCTCGGCCTCGCGCCGCGTGCCGCCTGCGTCGTCGGGGGCGACACAACGCCGCACCCGAAG
CCGCACCCGGCCCCGCTGCTGCATGCGGCCGACCAGCTGACGCTCGCGCCTGCGCGCATCGTCTACGTCGGCGACGACCT
GCGCGACATTCAGGCCGGCAGCGCCGCCGGCATGGCAACGGTCGCGGCCGCGTATGGCTATTGCGGCGACGGCGCCGCGC
CATCCGACTGGCAAGCGCAACATCTCGTCGACACGACGCAGCAACTGCGCGAACTGCTGCGCGATGTTGGGCTATAA

Upstream 100 bases:

>100_bases
ATCACGTATCACCCGATCGGCAAGCGCTTCGCGCTGTCGAACGACACCGACATCAACTACCTCGTCGCGTGCCGCCGCGG
CGCGTGACCTTCCAACCGGC

Downstream 100 bases:

>100_bases
TGGTCGATCTTATCCGCGGGGGCGACCTGGTTTCGACAGGGGTTGTGAAGCGGCTAGGGCATGTCGAGGACCCGTCACCT
CGTTAATCAATGGGAAAATC

Product: 2-phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTTPLSTARAALDEPRLLHCDAVLFDLDGTLADTAPDLAAAVNKMQRVRDLPETPLDVLRPLASAGARGLLGGAFGIDPQ
TPGYEAMRDEFLANYATDLCVHTTLFPGIGDVLDELDARGVRWGIVTNKAMRLTAPLVDLLGLAPRAACVVGGDTTPHPK
PHPAPLLHAADQLTLAPARIVYVGDDLRDIQAGSAAGMATVAAAYGYCGDGAAPSDWQAQHLVDTTQQLRELLRDVGL

Sequences:

>Translated_238_residues
MTTPLSTARAALDEPRLLHCDAVLFDLDGTLADTAPDLAAAVNKMQRVRDLPETPLDVLRPLASAGARGLLGGAFGIDPQ
TPGYEAMRDEFLANYATDLCVHTTLFPGIGDVLDELDARGVRWGIVTNKAMRLTAPLVDLLGLAPRAACVVGGDTTPHPK
PHPAPLLHAADQLTLAPARIVYVGDDLRDIQAGSAAGMATVAAAYGYCGDGAAPSDWQAQHLVDTTQQLRELLRDVGL
>Mature_237_residues
TTPLSTARAALDEPRLLHCDAVLFDLDGTLADTAPDLAAAVNKMQRVRDLPETPLDVLRPLASAGARGLLGGAFGIDPQT
PGYEAMRDEFLANYATDLCVHTTLFPGIGDVLDELDARGVRWGIVTNKAMRLTAPLVDLLGLAPRAACVVGGDTTPHPKP
HPAPLLHAADQLTLAPARIVYVGDDLRDIQAGSAAGMATVAAAYGYCGDGAAPSDWQAQHLVDTTQQLRELLRDVGL

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=205, Percent_Identity=36.0975609756098, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25062; Mature: 24931

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPLSTARAALDEPRLLHCDAVLFDLDGTLADTAPDLAAAVNKMQRVRDLPETPLDVLR
CCCCHHHHHHHHCCCCEEECCEEEEECCCCHHHCCHHHHHHHHHHHHHHCCCCCHHHHHH
PLASAGARGLLGGAFGIDPQTPGYEAMRDEFLANYATDLCVHTTLFPGIGDVLDELDARG
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
VRWGIVTNKAMRLTAPLVDLLGLAPRAACVVGGDTTPHPKPHPAPLLHAADQLTLAPARI
EEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCCEECCEEE
VYVGDDLRDIQAGSAAGMATVAAAYGYCGDGAAPSDWQAQHLVDTTQQLRELLRDVGL
EEECCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTPLSTARAALDEPRLLHCDAVLFDLDGTLADTAPDLAAAVNKMQRVRDLPETPLDVLR
CCCHHHHHHHHCCCCEEECCEEEEECCCCHHHCCHHHHHHHHHHHHHHCCCCCHHHHHH
PLASAGARGLLGGAFGIDPQTPGYEAMRDEFLANYATDLCVHTTLFPGIGDVLDELDARG
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
VRWGIVTNKAMRLTAPLVDLLGLAPRAACVVGGDTTPHPKPHPAPLLHAADQLTLAPARI
EEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCCEECCEEE
VYVGDDLRDIQAGSAAGMATVAAAYGYCGDGAAPSDWQAQHLVDTTQQLRELLRDVGL
EEECCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA