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The map label for this gene is sugE [H]

Identifier: 78065508

GI number: 78065508

Start: 961605

End: 961946

Strand: Reverse

Name: sugE [H]

Synonym: Bcep18194_A4036

Alternate gene names: 78065508

Gene position: 961946-961605 (Counterclockwise)

Preceding gene: 78065509

Following gene: 78065507

Centisome position: 26.04

GC content: 66.37

Gene sequence:

>342_bases
GTGTCCCCGCTCCAGTCTGCCTGGCTTCTGCTGGGCGTCAGTGTCCTCGCCGAAGTACTCGGCTCCGTCGGCCTGAAATA
TTCGGCCGGCTTTTCCCGCCCGCTCCCCTCCGCACTCACCGTCGTCTGTTACGCATGCGCGGTCTGGCTGATGGCGCTCG
CGACGAAACGCCTCGAAATGGGGCTCGCATATGCAAGCTGGGCCGCCGCCAGCACCGCGGCCACGGCTGTGATCGGCATC
GTCTGCTTCGACGAATCGACATCGTCGCTGAAGCTCGCCGGCATCGCGCTGACCGTGTGTGCGCTTGTCGCGCTCAACCT
CGGCGACGCGGCGACGCACTGA

Upstream 100 bases:

>100_bases
TGCGAAGGCGCGCGGACTAAGCTTCGTTCATCCTGGGTACCGCTGACACCCCCACTTCTCCTCACCGCTCGGTATAAGCG
TCGGGGGAAGGAGGCCGTTC

Downstream 100 bases:

>100_bases
CCGCGATCACCACCGGTTGCCGGCACGCGGGCATCGGGGAGACATTGACAACGCCCCCCGACGCCCCTTAACGTTGCTCC
CATCGTAACCATCACCGGTT

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MSPLQSAWLLLGVSVLAEVLGSVGLKYSAGFSRPLPSALTVVCYACAVWLMALATKRLEMGLAYASWAAASTAATAVIGI
VCFDESTSSLKLAGIALTVCALVALNLGDAATH

Sequences:

>Translated_113_residues
MSPLQSAWLLLGVSVLAEVLGSVGLKYSAGFSRPLPSALTVVCYACAVWLMALATKRLEMGLAYASWAAASTAATAVIGI
VCFDESTSSLKLAGIALTVCALVALNLGDAATH
>Mature_112_residues
SPLQSAWLLLGVSVLAEVLGSVGLKYSAGFSRPLPSALTVVCYACAVWLMALATKRLEMGLAYASWAAASTAATAVIGIV
CFDESTSSLKLAGIALTVCALVALNLGDAATH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=107, Percent_Identity=40.1869158878505, Blast_Score=74, Evalue=2e-15,
Organism=Escherichia coli, GI1786755, Length=108, Percent_Identity=28.7037037037037, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11505; Mature: 11373

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLQSAWLLLGVSVLAEVLGSVGLKYSAGFSRPLPSALTVVCYACAVWLMALATKRLEM
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLAYASWAAASTAATAVIGIVCFDESTSSLKLAGIALTVCALVALNLGDAATH
HHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SPLQSAWLLLGVSVLAEVLGSVGLKYSAGFSRPLPSALTVVCYACAVWLMALATKRLEM
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLAYASWAAASTAATAVIGIVCFDESTSSLKLAGIALTVCALVALNLGDAATH
HHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]