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The map label for this gene is srlR [H]

Identifier: 77461944

GI number: 77461944

Start: 6420028

End: 6420804

Strand: Reverse

Name: srlR [H]

Synonym: Pfl01_5727

Alternate gene names: 77461944

Gene position: 6420804-6420028 (Counterclockwise)

Preceding gene: 77461945

Following gene: 77461943

Centisome position: 99.73

GC content: 58.69

Gene sequence:

>777_bases
ATGTCGAAACGCAATACACCTCAGCGCCGTCACAACATTCTGGCTTTGCTCAATGAGCAGGGCGAGGTGAGTGTGGATGA
ACTGGCCAAGCGCTTCGAAACTTCCGAAGTTACGATTCGCAAGGATCTCGCTGCCTTGGAAGGTCATGGCCTGCTGCTGC
GTCGCTACGGCGGAGCCATCACCATGCCGCAGGAGCTGGTGGCAGACACCAGCCTCAACGTTTCCAAATACAAGCAGGCG
ATTGCCCGGGCTGCGGTCAAACGCATCCGTGAACACGCCCGCATCATCATCGACAGCGGCAGCACCACCGCCGCCATGAT
CCCCGAGCTCGGCCAGCAGCCGGGACTGGTGGTGATGACCAACTCCCTGCACGTGGCCAACGCCCTGAGTGAGCTCGAGC
ACGAGCCTGTGCTGCTGATGACCGGCGGCACCTGGGATCCGCACTCGGAATCCTTTCAGGGCCAGGTCGCCGAGCAGGTA
CTACGCTCTTACGACTTCGACCAGTTGTTTATCGGTGCCGATGGCATCGACCTGGTACGTGGTACCACCACGTTCAATGA
ATTGCTCGGCCTGAGCCGGGTGATGGCGGAAGTGGCGCGGGAAGTGATCGTGATGGTCGAAGCCGACAAGATCGGCCGCA
AGATTCCCAACCTGGAGCTGCCATGGAGCAGTGTCCATACCCTAATTACCGATGATCGCCTGCCTTTAGATGCACGCGAT
CAGATTCAGGCTCGCGGTATCAACTTGATTTGCGCGACTGTCAGTCAGGAGAAATAA

Upstream 100 bases:

>100_bases
ACCGCTGCCAGCGGTCTTTTTTTTGGGCGCCGGCTTGACGATTCGCAGCTGATAGGTTTTGATTGCTTCCGTTATCTTTC
GAATCGAAACTTAATCAGCC

Downstream 100 bases:

>100_bases
GCATGTGTGGAATTGTCGGCGCCGTTGCTGAACGTAATATCACCGCCATCCTGCTCGAAGGCCTCAAGCGTCTGGAATAC
CGGGGCTATGACAGTGCAGG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSKRNTPQRRHNILALLNEQGEVSVDELAKRFETSEVTIRKDLAALEGHGLLLRRYGGAITMPQELVADTSLNVSKYKQA
IARAAVKRIREHARIIIDSGSTTAAMIPELGQQPGLVVMTNSLHVANALSELEHEPVLLMTGGTWDPHSESFQGQVAEQV
LRSYDFDQLFIGADGIDLVRGTTTFNELLGLSRVMAEVAREVIVMVEADKIGRKIPNLELPWSSVHTLITDDRLPLDARD
QIQARGINLICATVSQEK

Sequences:

>Translated_258_residues
MSKRNTPQRRHNILALLNEQGEVSVDELAKRFETSEVTIRKDLAALEGHGLLLRRYGGAITMPQELVADTSLNVSKYKQA
IARAAVKRIREHARIIIDSGSTTAAMIPELGQQPGLVVMTNSLHVANALSELEHEPVLLMTGGTWDPHSESFQGQVAEQV
LRSYDFDQLFIGADGIDLVRGTTTFNELLGLSRVMAEVAREVIVMVEADKIGRKIPNLELPWSSVHTLITDDRLPLDARD
QIQARGINLICATVSQEK
>Mature_257_residues
SKRNTPQRRHNILALLNEQGEVSVDELAKRFETSEVTIRKDLAALEGHGLLLRRYGGAITMPQELVADTSLNVSKYKQAI
ARAAVKRIREHARIIIDSGSTTAAMIPELGQQPGLVVMTNSLHVANALSELEHEPVLLMTGGTWDPHSESFQGQVAEQVL
RSYDFDQLFIGADGIDLVRGTTTFNELLGLSRVMAEVAREVIVMVEADKIGRKIPNLELPWSSVHTLITDDRLPLDARDQ
IQARGINLICATVSQEK

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=45.2755905511811, Blast_Score=210, Evalue=9e-56,
Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=39.9209486166008, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI226510968, Length=251, Percent_Identity=31.8725099601594, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788069, Length=216, Percent_Identity=30.5555555555556, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787540, Length=228, Percent_Identity=30.2631578947368, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789829, Length=212, Percent_Identity=29.7169811320755, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=26.5873015873016, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87082344, Length=258, Percent_Identity=27.1317829457364, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790753, Length=254, Percent_Identity=25.1968503937008, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28509; Mature: 28378

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRNTPQRRHNILALLNEQGEVSVDELAKRFETSEVTIRKDLAALEGHGLLLRRYGGAI
CCCCCCCHHHHHHHEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCC
TMPQELVADTSLNVSKYKQAIARAAVKRIREHARIIIDSGSTTAAMIPELGQQPGLVVMT
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCEEEEE
NSLHVANALSELEHEPVLLMTGGTWDPHSESFQGQVAEQVLRSYDFDQLFIGADGIDLVR
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHC
GTTTFNELLGLSRVMAEVAREVIVMVEADKIGRKIPNLELPWSSVHTLITDDRLPLDARD
CCHHHHHHHHHHHHHHHHHHHHEEEEECHHHHCCCCCCCCCHHHHHHHEECCCCCCCCHH
QIQARGINLICATVSQEK
HHHHCCCEEEEEECCCCC
>Mature Secondary Structure 
SKRNTPQRRHNILALLNEQGEVSVDELAKRFETSEVTIRKDLAALEGHGLLLRRYGGAI
CCCCCCHHHHHHHEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCC
TMPQELVADTSLNVSKYKQAIARAAVKRIREHARIIIDSGSTTAAMIPELGQQPGLVVMT
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCEEEEE
NSLHVANALSELEHEPVLLMTGGTWDPHSESFQGQVAEQVLRSYDFDQLFIGADGIDLVR
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHC
GTTTFNELLGLSRVMAEVAREVIVMVEADKIGRKIPNLELPWSSVHTLITDDRLPLDARD
CCHHHHHHHHHHHHHHHHHHHHEEEEECHHHHCCCCCCCCCHHHHHHHEECCCCCCCCHH
QIQARGINLICATVSQEK
HHHHCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]