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The map label for this gene is glmU [H]

Identifier: 77461945

GI number: 77461945

Start: 6420934

End: 6422301

Strand: Reverse

Name: glmU [H]

Synonym: Pfl01_5728

Alternate gene names: 77461945

Gene position: 6422301-6420934 (Counterclockwise)

Preceding gene: 77461946

Following gene: 77461944

Centisome position: 99.75

GC content: 61.04

Gene sequence:

>1368_bases
ATGTCTCTTGAAATCGTTATCCTCGCGGCCGGTCAAGGCACCCGCATGCGTTCCGCGCTGCCAAAAGTGCTGCACCCGAT
TGCCGGCGATTCCATGCTTGGCCATGTTATCCACAGCGCCCGTCAACTTGATCCACAGCGCATTCATGTCGTCATCGGTC
ACGGCGCTGATGTGGTACGGGAGCGTCTGGCCGCTGACGATCTGAATTTCGTGCTGCAGGACAAGCAACTGGGCACTGGC
CACGCCACCGCCCAGGCTGTTCCGTTCATCACCGCCGATACCGTACTGATTCTCTACGGCGATGTGCCGTTGATCGAAGT
CGAGACCCTGCAGCGTCTGCTCAAGCACGTTGTACCCGGGCAGATGGGTTTGCTCACCGTCGAGCTGGACGACCCGACCG
GTTATGGTCGCATCGTGCGCGATGCCGATGGCAAGGTCGCCGCGATCGTCGAACACAAGGACGCCAGCGAAGCACAGCGG
GCGATCACTGAAGGCAACACCGGCATCCTGGCGGTGCCGGCCAATCGCCTGGCGGACTGGATGAGTCGCCTGTCGAACAA
CAACGCGCAGGGCGAGTATTACCTGACCGACGTGATCGAGATGGCAGTCAGCGACGGCCTGACGGTCGCCACCGAACAAC
CTCACGACCCGATGGAAGTGCAGGGCGCCAACGATCGCAAACAACTGTCCGAGCTGGAGCGTCATTACCAGTTGCGCGCC
GGTCGTCGACTGATGGCTCAGGGTGTCACCCTGCGCGACCCGGCCCGTTTCGATGTACGTGGCGAAGTGACCGTGGGTCG
CGATGTCCTGATCGACATCAACGTGATTCTCGAAGGCAAGGTCGTCATCGAGGACGACGTAGTCATCGGCCCGAACTGCG
TGATCAAGGACAGCACCCTGCGCAAAGGCGTGGTGATCAAGGCCAACAGCCACATCGAAGGTGCGGTGTTGGGCGAAGGC
AGCGATGCCGGCCCGTTTGCCCGTCTGCGTCCGGGCACTGTGCTGGAGGCCCGCGCCCATGTGGGTAACTTCGTTGAACT
GAAAAACGCGCGCATGGGCGAAGGCGCCAAGGCCGGGCACCTGACTTACCTGGGCGATGCCGAGATCGGTGCGCGTACCA
ACATCGGCGCCGGCACCATCACTTGCAACTACGATGGCGCCAACAAGTGGAAAACCGTGTTGGGTGAAGACGTGTTCATC
GGTTCCAACAACTCGCTGGTGGCGCCTGTGGATATCTCCGCCGGTGCCACTACTGCAGCCGGTTCGACCATCACCCAGAA
TGTGGAAAACTCCCAATTGGCGGTTGGCCGCGCACGCCAGAAGAACATCGATGGCTGGAAGCGGCCGGAGAAGATCAAGA
AGAACTGA

Upstream 100 bases:

>100_bases
TGCGATTGATAAAAAAGGGTAGCCTCGGCTACCCTTTTTTCTTTTCAGAATTCTACAAACCCGGTCGCAGTTGCTGACCA
CCCAGGATTGGTAGCCAGTC

Downstream 100 bases:

>100_bases
GTTATCCACAATGCTCAAATTAAAAAAGGACCGCTGCCAGCGGTCTTTTTTTTGGGCGCCGGCTTGACGATTCGCAGCTG
ATAGGTTTTGATTGCTTCCG

Product: UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSLEIVILAAGQGTRMRSALPKVLHPIAGDSMLGHVIHSARQLDPQRIHVVIGHGADVVRERLAADDLNFVLQDKQLGTG
HATAQAVPFITADTVLILYGDVPLIEVETLQRLLKHVVPGQMGLLTVELDDPTGYGRIVRDADGKVAAIVEHKDASEAQR
AITEGNTGILAVPANRLADWMSRLSNNNAQGEYYLTDVIEMAVSDGLTVATEQPHDPMEVQGANDRKQLSELERHYQLRA
GRRLMAQGVTLRDPARFDVRGEVTVGRDVLIDINVILEGKVVIEDDVVIGPNCVIKDSTLRKGVVIKANSHIEGAVLGEG
SDAGPFARLRPGTVLEARAHVGNFVELKNARMGEGAKAGHLTYLGDAEIGARTNIGAGTITCNYDGANKWKTVLGEDVFI
GSNNSLVAPVDISAGATTAAGSTITQNVENSQLAVGRARQKNIDGWKRPEKIKKN

Sequences:

>Translated_455_residues
MSLEIVILAAGQGTRMRSALPKVLHPIAGDSMLGHVIHSARQLDPQRIHVVIGHGADVVRERLAADDLNFVLQDKQLGTG
HATAQAVPFITADTVLILYGDVPLIEVETLQRLLKHVVPGQMGLLTVELDDPTGYGRIVRDADGKVAAIVEHKDASEAQR
AITEGNTGILAVPANRLADWMSRLSNNNAQGEYYLTDVIEMAVSDGLTVATEQPHDPMEVQGANDRKQLSELERHYQLRA
GRRLMAQGVTLRDPARFDVRGEVTVGRDVLIDINVILEGKVVIEDDVVIGPNCVIKDSTLRKGVVIKANSHIEGAVLGEG
SDAGPFARLRPGTVLEARAHVGNFVELKNARMGEGAKAGHLTYLGDAEIGARTNIGAGTITCNYDGANKWKTVLGEDVFI
GSNNSLVAPVDISAGATTAAGSTITQNVENSQLAVGRARQKNIDGWKRPEKIKKN
>Mature_454_residues
SLEIVILAAGQGTRMRSALPKVLHPIAGDSMLGHVIHSARQLDPQRIHVVIGHGADVVRERLAADDLNFVLQDKQLGTGH
ATAQAVPFITADTVLILYGDVPLIEVETLQRLLKHVVPGQMGLLTVELDDPTGYGRIVRDADGKVAAIVEHKDASEAQRA
ITEGNTGILAVPANRLADWMSRLSNNNAQGEYYLTDVIEMAVSDGLTVATEQPHDPMEVQGANDRKQLSELERHYQLRAG
RRLMAQGVTLRDPARFDVRGEVTVGRDVLIDINVILEGKVVIEDDVVIGPNCVIKDSTLRKGVVIKANSHIEGAVLGEGS
DAGPFARLRPGTVLEARAHVGNFVELKNARMGEGAKAGHLTYLGDAEIGARTNIGAGTITCNYDGANKWKTVLGEDVFIG
SNNSLVAPVDISAGATTAAGSTITQNVENSQLAVGRARQKNIDGWKRPEKIKKN

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=453, Percent_Identity=56.5121412803532, Blast_Score=504, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR001451
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep; PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 48814; Mature: 48683

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEIVILAAGQGTRMRSALPKVLHPIAGDSMLGHVIHSARQLDPQRIHVVIGHGADVVR
CCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCHHHHH
ERLAADDLNFVLQDKQLGTGHATAQAVPFITADTVLILYGDVPLIEVETLQRLLKHVVPG
HHHHHCCCCEEEECCCCCCCCCHHHCCCEEECCEEEEEECCCCEEEHHHHHHHHHHHCCC
QMGLLTVELDDPTGYGRIVRDADGKVAAIVEHKDASEAQRAITEGNTGILAVPANRLADW
CCEEEEEEECCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHCCCCEEEEECHHHHHHH
MSRLSNNNAQGEYYLTDVIEMAVSDGLTVATEQPHDPMEVQGANDRKQLSELERHYQLRA
HHHHCCCCCCCCEEHHHHHHHHHHCCEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHH
GRRLMAQGVTLRDPARFDVRGEVTVGRDVLIDINVILEGKVVIEDDVVIGPNCVIKDSTL
HHHHHHCCCEECCCCCCCEEEEEEECCEEEEEEEEEEECEEEEECCEEECCCEEEECCCC
RKGVVIKANSHIEGAVLGEGSDAGPFARLRPGTVLEARAHVGNFVELKNARMGEGAKAGH
CCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEEHHHCCCEEEECCCCCCCCCCCCC
LTYLGDAEIGARTNIGAGTITCNYDGANKWKTVLGEDVFIGSNNSLVAPVDISAGATTAA
EEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCEEEECCCCCEEEEEECCCCCCCCC
GSTITQNVENSQLAVGRARQKNIDGWKRPEKIKKN
CCHHCCCCCCCEEEECCHHHCCCCCCCCCHHHCCC
>Mature Secondary Structure 
SLEIVILAAGQGTRMRSALPKVLHPIAGDSMLGHVIHSARQLDPQRIHVVIGHGADVVR
CEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCHHHHH
ERLAADDLNFVLQDKQLGTGHATAQAVPFITADTVLILYGDVPLIEVETLQRLLKHVVPG
HHHHHCCCCEEEECCCCCCCCCHHHCCCEEECCEEEEEECCCCEEEHHHHHHHHHHHCCC
QMGLLTVELDDPTGYGRIVRDADGKVAAIVEHKDASEAQRAITEGNTGILAVPANRLADW
CCEEEEEEECCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHCCCCEEEEECHHHHHHH
MSRLSNNNAQGEYYLTDVIEMAVSDGLTVATEQPHDPMEVQGANDRKQLSELERHYQLRA
HHHHCCCCCCCCEEHHHHHHHHHHCCEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHH
GRRLMAQGVTLRDPARFDVRGEVTVGRDVLIDINVILEGKVVIEDDVVIGPNCVIKDSTL
HHHHHHCCCEECCCCCCCEEEEEEECCEEEEEEEEEEECEEEEECCEEECCCEEEECCCC
RKGVVIKANSHIEGAVLGEGSDAGPFARLRPGTVLEARAHVGNFVELKNARMGEGAKAGH
CCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEEHHHCCCEEEECCCCCCCCCCCCC
LTYLGDAEIGARTNIGAGTITCNYDGANKWKTVLGEDVFIGSNNSLVAPVDISAGATTAA
EEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCEEEECCCCCEEEEEECCCCCCCCC
GSTITQNVENSQLAVGRARQKNIDGWKRPEKIKKN
CCHHCCCCCCCEEEECCHHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA