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The map label for this gene is hemX [H]

Identifier: 77461706

GI number: 77461706

Start: 6152725

End: 6153867

Strand: Reverse

Name: hemX [H]

Synonym: Pfl01_5485

Alternate gene names: 77461706

Gene position: 6153867-6152725 (Counterclockwise)

Preceding gene: 77461707

Following gene: 77461705

Centisome position: 95.58

GC content: 64.48

Gene sequence:

>1143_bases
GTGAGCGAAACAGCCTTGCCTAAAGATGACGTTCAACCTGTGATCGATACACCGGTTGATGCACCGCCACCGGCCGCGGA
ACCGCGCCGAGGCAACGGATTGGCCATTCTCGCGCTGCTGCTCGGCGCCGCCGGTGTTGCGGTGGGTGGCTGGGGTGTCT
GGCAGGTGCGACATCTGCAGGCCAACACGCAAAATCAATTGAGTCAGGTTCAGGCATTGAGCGATCAGGCCCAGACCCTG
AAGCTCAACGAGCAACGACTGACCGAGCGCCTCGGGCAATTGCCTGGCGCCGATGAGCTTGCTGATCGCCAGCGTCTGGT
GTCGCAACTTCAGGGCGATCAGCAGCGCCTCAATCAACGCCTGGAAACCGTCCTCGGCGCCAGCCGCAAGGACTGGCGCC
TGGCCGAGGCCGAGCACTTGCTGCGTCTGGCCAGCCTGCGTCTTTCCGCCCTGCAGGACATCAGCAGCGCCCAGGCGCTG
GTCCAGGGTGCCGACGAAATCCTGCGCGAGCAGAACGATCCCGGCTCGTTCGCCGCCCGCGAGCAAGTGGCGAAAACTCT
TGTAGCGCTGCGCAGTACCGAGCAGCCGGATCGCACCGGGCTGTTCCTGCGCCTGGGCGCCTTGCGCGATCAGGTCGTCG
GTCTCACCGAGCTGGCGCCGGAGTACAAGGATCGCGGCGATTCGCTGTTGGGCCTGACTTCCGATGGCGACGGTGCCAGT
CGTTGGGCGCAGTGGTGGGATCAGATCTCGCGCTATATCCGCATCGATTTCAACGCCGACAAGAACGTCCGGCCGCTGCT
CGCCGGCCAGAGCCTGAGCCAGGTGCGTCTGGCCCTGAGCCTTGCGCTCGAGCAGGCGCAATGGGCCGCGCTCAACGGTC
AGGCGCCGGTGTACACCCAGGCCCTGGCCGAAGCGCGTGACGTCCTCACGGGCAACTTCAACCCGGACAACCCGCAGAGC
AAAATCATGCTCGAACAGGTCGCGGAACTGAGCAAGCAACCGGTTACCGTCAACACGCCGGATCTCACCGGAACCTTGAG
CACGGTGCAGGCCTATCTGGAGCGCCGTAACGTCAACGCCGAAGACTCGGTGAAACCCTTCGCCAAACCGGCCGCAAGTA
CCGCGCAGGAGGCGACACCATGA

Upstream 100 bases:

>100_bases
GCCCGAACAGTTGTGGATTGTCGCGGCGCCAGTGCTGCGGCCTTGCTGACGGCGTTACGGGAGCATCCCGTGCCCGTTCT
CTAATGCAAAGGATGGATAC

Downstream 100 bases:

>100_bases
AGCGCCTGTATGTGATCGTGTTTCTGGTGATCGCGGCAACGGCGGCGCTGGGTCTGGCGATTGCCGAGCATTCCGGTTAC
GTGCTGGTCGCCTACAAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSETALPKDDVQPVIDTPVDAPPPAAEPRRGNGLAILALLLGAAGVAVGGWGVWQVRHLQANTQNQLSQVQALSDQAQTL
KLNEQRLTERLGQLPGADELADRQRLVSQLQGDQQRLNQRLETVLGASRKDWRLAEAEHLLRLASLRLSALQDISSAQAL
VQGADEILREQNDPGSFAAREQVAKTLVALRSTEQPDRTGLFLRLGALRDQVVGLTELAPEYKDRGDSLLGLTSDGDGAS
RWAQWWDQISRYIRIDFNADKNVRPLLAGQSLSQVRLALSLALEQAQWAALNGQAPVYTQALAEARDVLTGNFNPDNPQS
KIMLEQVAELSKQPVTVNTPDLTGTLSTVQAYLERRNVNAEDSVKPFAKPAASTAQEATP

Sequences:

>Translated_380_residues
MSETALPKDDVQPVIDTPVDAPPPAAEPRRGNGLAILALLLGAAGVAVGGWGVWQVRHLQANTQNQLSQVQALSDQAQTL
KLNEQRLTERLGQLPGADELADRQRLVSQLQGDQQRLNQRLETVLGASRKDWRLAEAEHLLRLASLRLSALQDISSAQAL
VQGADEILREQNDPGSFAAREQVAKTLVALRSTEQPDRTGLFLRLGALRDQVVGLTELAPEYKDRGDSLLGLTSDGDGAS
RWAQWWDQISRYIRIDFNADKNVRPLLAGQSLSQVRLALSLALEQAQWAALNGQAPVYTQALAEARDVLTGNFNPDNPQS
KIMLEQVAELSKQPVTVNTPDLTGTLSTVQAYLERRNVNAEDSVKPFAKPAASTAQEATP
>Mature_379_residues
SETALPKDDVQPVIDTPVDAPPPAAEPRRGNGLAILALLLGAAGVAVGGWGVWQVRHLQANTQNQLSQVQALSDQAQTLK
LNEQRLTERLGQLPGADELADRQRLVSQLQGDQQRLNQRLETVLGASRKDWRLAEAEHLLRLASLRLSALQDISSAQALV
QGADEILREQNDPGSFAAREQVAKTLVALRSTEQPDRTGLFLRLGALRDQVVGLTELAPEYKDRGDSLLGLTSDGDGASR
WAQWWDQISRYIRIDFNADKNVRPLLAGQSLSQVRLALSLALEQAQWAALNGQAPVYTQALAEARDVLTGNFNPDNPQSK
IMLEQVAELSKQPVTVNTPDLTGTLSTVQAYLERRNVNAEDSVKPFAKPAASTAQEATP

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=378, Percent_Identity=27.5132275132275, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 41370; Mature: 41239

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETALPKDDVQPVIDTPVDAPPPAAEPRRGNGLAILALLLGAAGVAVGGWGVWQVRHLQ
CCCCCCCHHCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
ANTQNQLSQVQALSDQAQTLKLNEQRLTERLGQLPGADELADRQRLVSQLQGDQQRLNQR
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHH
LETVLGASRKDWRLAEAEHLLRLASLRLSALQDISSAQALVQGADEILREQNDPGSFAAR
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
EQVAKTLVALRSTEQPDRTGLFLRLGALRDQVVGLTELAPEYKDRGDSLLGLTSDGDGAS
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEECCCCCCHH
RWAQWWDQISRYIRIDFNADKNVRPLLAGQSLSQVRLALSLALEQAQWAALNGQAPVYTQ
HHHHHHHHHHHEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ALAEARDVLTGNFNPDNPQSKIMLEQVAELSKQPVTVNTPDLTGTLSTVQAYLERRNVNA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHCCCCC
EDSVKPFAKPAASTAQEATP
CCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SETALPKDDVQPVIDTPVDAPPPAAEPRRGNGLAILALLLGAAGVAVGGWGVWQVRHLQ
CCCCCCHHCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
ANTQNQLSQVQALSDQAQTLKLNEQRLTERLGQLPGADELADRQRLVSQLQGDQQRLNQR
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHH
LETVLGASRKDWRLAEAEHLLRLASLRLSALQDISSAQALVQGADEILREQNDPGSFAAR
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
EQVAKTLVALRSTEQPDRTGLFLRLGALRDQVVGLTELAPEYKDRGDSLLGLTSDGDGAS
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEECCCCCCHH
RWAQWWDQISRYIRIDFNADKNVRPLLAGQSLSQVRLALSLALEQAQWAALNGQAPVYTQ
HHHHHHHHHHHEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ALAEARDVLTGNFNPDNPQSKIMLEQVAELSKQPVTVNTPDLTGTLSTVQAYLERRNVNA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHCCCCC
EDSVKPFAKPAASTAQEATP
CCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]