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The map label for this gene is hemY [H]

Identifier: 77461705

GI number: 77461705

Start: 6151490

End: 6152728

Strand: Reverse

Name: hemY [H]

Synonym: Pfl01_5484

Alternate gene names: 77461705

Gene position: 6152728-6151490 (Counterclockwise)

Preceding gene: 77461706

Following gene: 77461704

Centisome position: 95.56

GC content: 64.73

Gene sequence:

>1239_bases
ATGAAGCGCCTGTATGTGATCGTGTTTCTGGTGATCGCGGCAACGGCGGCGCTGGGTCTGGCGATTGCCGAGCATTCCGG
TTACGTGCTGGTCGCCTACAAAAGCTTTCGTTATGAATCGAGCCTGTGGGCAACCCTGGCAGTGGTGGCGGTGCTGTGGC
TGCTGGTCTGGGGTATCAAGGCGCTGGTCGAACTGGTGCTGACCTCCGGCGGCGTGGTCAATCCATGGTCGCGTCGCAAC
CGCAGCCGTCGCGTGCAGGTGGCGATCGAGCACGGTCAGCTCGACCTGGCCGAAGGTCGCTGGGCCAGTGCCCAGCGTCA
CCTTTACCGGGCCGCCGAAGCCGAGCGTCAACCGTTGCTGTATTACCTGGGTGCCGCCCGCGCCGCCAACGAACAAGGCA
ACTACGAGGAAAGCGATCGCCTGCTGGAGCGCGCGCTCGAGCGTCAGCCGCAGGCCGAACTGGCGATCGCCCTCAGCCAT
GCGCAGTTGCAGACCGATCGTGGCGATACCGATGGTGCGCTGGTCACATTGCAGGCGATGCACGAGCGCCATCCGCACAA
TGTCCAGACCCTGCGTCAGTTGCAGCGCCTGCATCAGCAGCGCGGTGACTGGTCGTCAGTGATCCGGCTGTTGCCGGAGC
TGCGCAAGGACAAAGTTCTGCCACCGGCCGAACTGACCGAACTCGAGCGTCGTGCCTGGGGAGAAAACCTCTCCCTGGCG
GCGCATCGCGAAGAGGATGGTGCGGTGGGTTTGCAGTCGCTGAACCGGGCCTGGCAGCAACTGACGTCTGCCCAGCGTCA
GGAGCCTGCGCTGGTGCTGGCATACGCCGAGCAACTGCGTCAGCTGGGCGCTCAGGTAGAGGCGGAAGAAGTTTTGCGCA
CGGCGCTCAAGCGCAAGTACGACAGCCATCTGGCGCGCCTCTATGGTCTGGTACGTGGCAGTGACCCGGCGCGGCAGTTG
CAGACGGCGGAAGGCTGGCTCAAGGATCATCCGGGCGATGCCAGCCTGCTGCTGACGCTGGGACGTCTGTGCCTGCAAGC
CAGTCTTTGGGGCAAGGCGCGGGATTACCTGGAAAGCAGCCTGCGCGTGCAGCGCAATCCGGAAGCGTGCGCGGAACTGG
CTCGTCTTCTGGCACGGCTTGGCGACACTGACCGTAGCAACATGTTGTTCCAGGAGGGCCTCGGTCTGCTGGACGAGCGC
TTGCTCGCAGCACCGCTGCCGGTGGCGGCTCGCGCGTGA

Upstream 100 bases:

>100_bases
GCACGGTGCAGGCCTATCTGGAGCGCCGTAACGTCAACGCCGAAGACTCGGTGAAACCCTTCGCCAAACCGGCCGCAAGT
ACCGCGCAGGAGGCGACACC

Downstream 100 bases:

>100_bases
TCGGGATGGAGGAGCTTGCTCCTCCGTTTCTTCCCGAGTGATTGAATAACCTTCGGAAAACCACCTCCGGAACAAAGTCC
TACAGCGGACTTCGCAGAAT

Product: HemY-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKRLYVIVFLVIAATAALGLAIAEHSGYVLVAYKSFRYESSLWATLAVVAVLWLLVWGIKALVELVLTSGGVVNPWSRRN
RSRRVQVAIEHGQLDLAEGRWASAQRHLYRAAEAERQPLLYYLGAARAANEQGNYEESDRLLERALERQPQAELAIALSH
AQLQTDRGDTDGALVTLQAMHERHPHNVQTLRQLQRLHQQRGDWSSVIRLLPELRKDKVLPPAELTELERRAWGENLSLA
AHREEDGAVGLQSLNRAWQQLTSAQRQEPALVLAYAEQLRQLGAQVEAEEVLRTALKRKYDSHLARLYGLVRGSDPARQL
QTAEGWLKDHPGDASLLLTLGRLCLQASLWGKARDYLESSLRVQRNPEACAELARLLARLGDTDRSNMLFQEGLGLLDER
LLAAPLPVAARA

Sequences:

>Translated_412_residues
MKRLYVIVFLVIAATAALGLAIAEHSGYVLVAYKSFRYESSLWATLAVVAVLWLLVWGIKALVELVLTSGGVVNPWSRRN
RSRRVQVAIEHGQLDLAEGRWASAQRHLYRAAEAERQPLLYYLGAARAANEQGNYEESDRLLERALERQPQAELAIALSH
AQLQTDRGDTDGALVTLQAMHERHPHNVQTLRQLQRLHQQRGDWSSVIRLLPELRKDKVLPPAELTELERRAWGENLSLA
AHREEDGAVGLQSLNRAWQQLTSAQRQEPALVLAYAEQLRQLGAQVEAEEVLRTALKRKYDSHLARLYGLVRGSDPARQL
QTAEGWLKDHPGDASLLLTLGRLCLQASLWGKARDYLESSLRVQRNPEACAELARLLARLGDTDRSNMLFQEGLGLLDER
LLAAPLPVAARA
>Mature_412_residues
MKRLYVIVFLVIAATAALGLAIAEHSGYVLVAYKSFRYESSLWATLAVVAVLWLLVWGIKALVELVLTSGGVVNPWSRRN
RSRRVQVAIEHGQLDLAEGRWASAQRHLYRAAEAERQPLLYYLGAARAANEQGNYEESDRLLERALERQPQAELAIALSH
AQLQTDRGDTDGALVTLQAMHERHPHNVQTLRQLQRLHQQRGDWSSVIRLLPELRKDKVLPPAELTELERRAWGENLSLA
AHREEDGAVGLQSLNRAWQQLTSAQRQEPALVLAYAEQLRQLGAQVEAEEVLRTALKRKYDSHLARLYGLVRGSDPARQL
QTAEGWLKDHPGDASLLLTLGRLCLQASLWGKARDYLESSLRVQRNPEACAELARLLARLGDTDRSNMLFQEGLGLLDER
LLAAPLPVAARA

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1790234, Length=385, Percent_Identity=26.4935064935065, Blast_Score=118, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07219 HemY_N; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 46177; Mature: 46177

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLYVIVFLVIAATAALGLAIAEHSGYVLVAYKSFRYESSLWATLAVVAVLWLLVWGIK
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ALVELVLTSGGVVNPWSRRNRSRRVQVAIEHGQLDLAEGRWASAQRHLYRAAEAERQPLL
HHHHHHHHCCCCCCCHHHCCCCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHHCCCCHH
YYLGAARAANEQGNYEESDRLLERALERQPQAELAIALSHAQLQTDRGDTDGALVTLQAM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEHHHH
HERHPHNVQTLRQLQRLHQQRGDWSSVIRLLPELRKDKVLPPAELTELERRAWGENLSLA
HCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEE
AHREEDGAVGLQSLNRAWQQLTSAQRQEPALVLAYAEQLRQLGAQVEAEEVLRTALKRKY
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DSHLARLYGLVRGSDPARQLQTAEGWLKDHPGDASLLLTLGRLCLQASLWGKARDYLESS
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRVQRNPEACAELARLLARLGDTDRSNMLFQEGLGLLDERLLAAPLPVAARA
HHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKRLYVIVFLVIAATAALGLAIAEHSGYVLVAYKSFRYESSLWATLAVVAVLWLLVWGIK
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ALVELVLTSGGVVNPWSRRNRSRRVQVAIEHGQLDLAEGRWASAQRHLYRAAEAERQPLL
HHHHHHHHCCCCCCCHHHCCCCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHHCCCCHH
YYLGAARAANEQGNYEESDRLLERALERQPQAELAIALSHAQLQTDRGDTDGALVTLQAM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEHHHH
HERHPHNVQTLRQLQRLHQQRGDWSSVIRLLPELRKDKVLPPAELTELERRAWGENLSLA
HCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEE
AHREEDGAVGLQSLNRAWQQLTSAQRQEPALVLAYAEQLRQLGAQVEAEEVLRTALKRKY
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DSHLARLYGLVRGSDPARQLQTAEGWLKDHPGDASLLLTLGRLCLQASLWGKARDYLESS
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRVQRNPEACAELARLLARLGDTDRSNMLFQEGLGLLDERLLAAPLPVAARA
HHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]