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The map label for this gene is ygdL [H]

Identifier: 77457317

GI number: 77457317

Start: 1262327

End: 1263139

Strand: Direct

Name: ygdL [H]

Synonym: Pfl01_1090

Alternate gene names: 77457317

Gene position: 1262327-1263139 (Clockwise)

Preceding gene: 77457312

Following gene: 77457322

Centisome position: 19.61

GC content: 63.71

Gene sequence:

>813_bases
ATGAGTACAGAAGATCCGCGGTTTGCAGGCATCGCCCGTTTGTATGGCATCGAGGGCCTCGAGCGCCTGCGTGCAGCCCA
CGTGGCGATTGTCGGCGTTGGCGGCGTCGGTTCCTGGGCGGCGGAAGCGATGGCCCGTTGTGGGGTGGGCGAGATTTCGC
TGTTCGACCTCGACGACGTCTGCGTCAGCAACGCCAACCGCCAGTTGCACGCGCTCGACAGCACGGTCGGCAAACCCAAG
GTCGAGGTGATGGCCGAGCGTCTGCGCGGGATCAACCCGGACTGCACGGTGCACGCCGTGGCGGACTTCGTCACCCGCGA
CACCATGGCCGAATACATCACGCCGAACATCGACTGCGTGATCGACTGCATCGACGCGGTCAACGCAAAAGCCGCGCTGA
TCGCCTGGTGCAAACGGCGCAAGATCCAGATCATCACCACTGGCGGCGCCGGCGGGCAGATCGATCCGACGCTGATTCAG
GTCTGCGACCTCAACCGTACGTTCAATGATCCTCTGGCCTCGAAAGTGCGCTCCACGCTGCGTCGTGACTATGGTTTCTC
GCGCACTGTGACTCGCCATTACAGCGTGCCGTGCGTGTTCTCCACCGAACAGCTGCGCTATCCGAAACCGGACGGCAGCA
TCTGCCTGCAGAAGAGTTTTGTCGGCGACGGCGTGAAGCTGGACTGCGCCGGCGGGTTTGGCGCGGTGATGATGGTGACG
GCGACGTTCGGCATGGTCGCGGCGACCAAGGCTGTAGACAAGATTGTGGCGGGTGTTCGGCGCCCGGCGGATCGGGTCAA
GCCTCAGGCCTGA

Upstream 100 bases:

>100_bases
GCAGCTTTAATTAAAGCAGGCGCATTCGCCGTTCATAGCGCAAAGATGCTCTTGGCCGCCGACGGCCCTATAATGCGCGC
CGGTTTTCAGGGTAATGGTC

Downstream 100 bases:

>100_bases
AGCATAGGGCTGCGCAGCAGCCCTTTACTGCGCCAGCTCGTTCATCCGCTGCAGAACGGCATTCAAGCCATTGCTGCGCG
ACGGCGACAACTGCCGCGAC

Product: UBA/THIF-type NAD/FAD binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSTEDPRFAGIARLYGIEGLERLRAAHVAIVGVGGVGSWAAEAMARCGVGEISLFDLDDVCVSNANRQLHALDSTVGKPK
VEVMAERLRGINPDCTVHAVADFVTRDTMAEYITPNIDCVIDCIDAVNAKAALIAWCKRRKIQIITTGGAGGQIDPTLIQ
VCDLNRTFNDPLASKVRSTLRRDYGFSRTVTRHYSVPCVFSTEQLRYPKPDGSICLQKSFVGDGVKLDCAGGFGAVMMVT
ATFGMVAATKAVDKIVAGVRRPADRVKPQA

Sequences:

>Translated_270_residues
MSTEDPRFAGIARLYGIEGLERLRAAHVAIVGVGGVGSWAAEAMARCGVGEISLFDLDDVCVSNANRQLHALDSTVGKPK
VEVMAERLRGINPDCTVHAVADFVTRDTMAEYITPNIDCVIDCIDAVNAKAALIAWCKRRKIQIITTGGAGGQIDPTLIQ
VCDLNRTFNDPLASKVRSTLRRDYGFSRTVTRHYSVPCVFSTEQLRYPKPDGSICLQKSFVGDGVKLDCAGGFGAVMMVT
ATFGMVAATKAVDKIVAGVRRPADRVKPQA
>Mature_269_residues
STEDPRFAGIARLYGIEGLERLRAAHVAIVGVGGVGSWAAEAMARCGVGEISLFDLDDVCVSNANRQLHALDSTVGKPKV
EVMAERLRGINPDCTVHAVADFVTRDTMAEYITPNIDCVIDCIDAVNAKAALIAWCKRRKIQIITTGGAGGQIDPTLIQV
CDLNRTFNDPLASKVRSTLRRDYGFSRTVTRHYSVPCVFSTEQLRYPKPDGSICLQKSFVGDGVKLDCAGGFGAVMMVTA
TFGMVAATKAVDKIVAGVRRPADRVKPQA

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Escherichia coli, GI1789177, Length=255, Percent_Identity=55.6862745098039, Blast_Score=292, Evalue=2e-80,
Organism=Escherichia coli, GI1787048, Length=136, Percent_Identity=36.7647058823529, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082356, Length=140, Percent_Identity=32.8571428571429, Blast_Score=78, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6321790, Length=201, Percent_Identity=30.8457711442786, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322825, Length=198, Percent_Identity=34.3434343434343, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24582879, Length=123, Percent_Identity=32.520325203252, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641311, Length=153, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 29021; Mature: 28890

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEDPRFAGIARLYGIEGLERLRAAHVAIVGVGGVGSWAAEAMARCGVGEISLFDLDDV
CCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHCCCCCEEEECCHHH
CVSNANRQLHALDSTVGKPKVEVMAERLRGINPDCTVHAVADFVTRDTMAEYITPNIDCV
HHCCCCCEEEHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
IDCIDAVNAKAALIAWCKRRKIQIITTGGAGGQIDPTLIQVCDLNRTFNDPLASKVRSTL
HHHHHHCCCHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHEECCCCCCCCHHHHHHHHHH
RRDYGFSRTVTRHYSVPCVFSTEQLRYPKPDGSICLQKSFVGDGVKLDCAGGFGAVMMVT
HHHCCCCHHHHHHCCCCEEEEHHHCCCCCCCCCEEEEECCCCCCEEEEECCCCHHHHHHH
ATFGMVAATKAVDKIVAGVRRPADRVKPQA
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure 
STEDPRFAGIARLYGIEGLERLRAAHVAIVGVGGVGSWAAEAMARCGVGEISLFDLDDV
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHCCCCCEEEECCHHH
CVSNANRQLHALDSTVGKPKVEVMAERLRGINPDCTVHAVADFVTRDTMAEYITPNIDCV
HHCCCCCEEEHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
IDCIDAVNAKAALIAWCKRRKIQIITTGGAGGQIDPTLIQVCDLNRTFNDPLASKVRSTL
HHHHHHCCCHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHEECCCCCCCCHHHHHHHHHH
RRDYGFSRTVTRHYSVPCVFSTEQLRYPKPDGSICLQKSFVGDGVKLDCAGGFGAVMMVT
HHHCCCCHHHHHHCCCCEEEEHHHCCCCCCCCCEEEEECCCCCCEEEEECCCCHHHHHHH
ATFGMVAATKAVDKIVAGVRRPADRVKPQA
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]