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The map label for this gene is ldh [H]

Identifier: 77457142

GI number: 77457142

Start: 1065925

End: 1066944

Strand: Direct

Name: ldh [H]

Synonym: Pfl01_0915

Alternate gene names: 77457142

Gene position: 1065925-1066944 (Clockwise)

Preceding gene: 77457140

Following gene: 77457144

Centisome position: 16.56

GC content: 63.43

Gene sequence:

>1020_bases
ATGTTCGCTCTCATGCAAAGCACTCGCCTGGAATCGCTGCACCTTAGCGTTGATCCGGTGTCCGGATTGAAGGCGGTCAT
TGCCATCCATAACAGTCGCCTCGGGCCAGCCCTGGGCGGGTGTCGTTATCTTGCCTATCCGAACGACGAATCCGCAGTCG
AGGATGCCATACGCCTGGCCCAGGGCATGAGCTACAAGGCCGCATTGGCTGGTCTCGCCCAAGGCGGTGGGGTGGCCGTG
ATCGTGCGGCCGGCCCACGTGGAAAACCGCGCCGCACTGTTCGAAGCCTTCGGCCGTTGCATCGATCAGCTCGACGGGCG
CTACATCACCGCCATCGACAGCGGCACTTCGGTGGCGGACATGGATTGCATCGCCCAGCAGACCCAGCATGTCACCAGTA
CCACCTCGGCCGGCGACCCTGCACCGCATGCGGCGATGGGCGTGTTCACCGGGATTCGCGCCACTGCGATGGCACGGCTC
GGTAGCGACAACCTCGAAGGCTTGCGCGTGGCGATTCAGGGGTTGGGCAATGTTGGTTATGCCTTGGCCGAACAGTTGCA
CGCCGCCGGCGCCGAACTGCTGGTCAGCGACATCGACCACGGCAAGGTGCAACTGGCGATGGAACAACTCAACGCCCATC
CGATCGCCAACGACGCGTTGCTCAGCACGCCGTGCGACATCCTCGCGCCGTGCGGTTTGGGCGGTGTGCTCAACAGCCAC
ACGGTCACCCAGTTGCGCTGCTCGGCGGTGGCGGGTTCGGCCAACAATCAGCTGACGCACCTGGACGTCGCCGATCAACT
GGAACGGCGCGGCATCCTGTATGCGCCGGATTACGTGATCAATGCCGGCGGGCTGATCTACGTTTCCCTCAAGCACCGGG
GCGAAGAGCTGACGACCATCACTGCGCACCTGTCGAAGATCAGCTCGCGCCTTACCGAAGTCTTCGCCCACGCCCAGGCG
GAAAAACGTTCACCCGCGCGGGTGGCTGACGAACTGGCGGAAAAGGTGTTGTACCGCTGA

Upstream 100 bases:

>100_bases
AACCCTGTAATCGGTGGCGGCGCTTATTCCGGTGCGCTTCAGCAATTTTCGGGCGCAAGCCTATACTGGCGTCTACCAGA
AGTGATTCGGGAGCCTGCCG

Downstream 100 bases:

>100_bases
GATTCGTCCGGGCATGAAAAAGCCCCTGAGTCTTTCAACTCAGGGGCTATTCAATTCAGAGGCTTCAATTACTTCGCAGC
CTTTGCCGCTTTGGCAGGTT

Product: Glu/Leu/Phe/Val dehydrogenase, dimerization region

Products: NA

Alternate protein names: LeuDH [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MFALMQSTRLESLHLSVDPVSGLKAVIAIHNSRLGPALGGCRYLAYPNDESAVEDAIRLAQGMSYKAALAGLAQGGGVAV
IVRPAHVENRAALFEAFGRCIDQLDGRYITAIDSGTSVADMDCIAQQTQHVTSTTSAGDPAPHAAMGVFTGIRATAMARL
GSDNLEGLRVAIQGLGNVGYALAEQLHAAGAELLVSDIDHGKVQLAMEQLNAHPIANDALLSTPCDILAPCGLGGVLNSH
TVTQLRCSAVAGSANNQLTHLDVADQLERRGILYAPDYVINAGGLIYVSLKHRGEELTTITAHLSKISSRLTEVFAHAQA
EKRSPARVADELAEKVLYR

Sequences:

>Translated_339_residues
MFALMQSTRLESLHLSVDPVSGLKAVIAIHNSRLGPALGGCRYLAYPNDESAVEDAIRLAQGMSYKAALAGLAQGGGVAV
IVRPAHVENRAALFEAFGRCIDQLDGRYITAIDSGTSVADMDCIAQQTQHVTSTTSAGDPAPHAAMGVFTGIRATAMARL
GSDNLEGLRVAIQGLGNVGYALAEQLHAAGAELLVSDIDHGKVQLAMEQLNAHPIANDALLSTPCDILAPCGLGGVLNSH
TVTQLRCSAVAGSANNQLTHLDVADQLERRGILYAPDYVINAGGLIYVSLKHRGEELTTITAHLSKISSRLTEVFAHAQA
EKRSPARVADELAEKVLYR
>Mature_339_residues
MFALMQSTRLESLHLSVDPVSGLKAVIAIHNSRLGPALGGCRYLAYPNDESAVEDAIRLAQGMSYKAALAGLAQGGGVAV
IVRPAHVENRAALFEAFGRCIDQLDGRYITAIDSGTSVADMDCIAQQTQHVTSTTSAGDPAPHAAMGVFTGIRATAMARL
GSDNLEGLRVAIQGLGNVGYALAEQLHAAGAELLVSDIDHGKVQLAMEQLNAHPIANDALLSTPCDILAPCGLGGVLNSH
TVTQLRCSAVAGSANNQLTHLDVADQLERRGILYAPDYVINAGGLIYVSLKHRGEELTTITAHLSKISSRLTEVFAHAQA
EKRSPARVADELAEKVLYR

Specific function: Functions catabolically in the bacterial metabolism of branched-chain L-amino acids, and plays an important role in spore germination in cooperation with alanine dehydrogenase [H]

COG id: COG0334

COG function: function code E; Glutamate dehydrogenase/leucine dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006095
- InterPro:   IPR006096
- InterPro:   IPR006097
- InterPro:   IPR016211
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00208 ELFV_dehydrog; PF02812 ELFV_dehydrog_N [H]

EC number: =1.4.1.9 [H]

Molecular weight: Translated: 35704; Mature: 35704

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFALMQSTRLESLHLSVDPVSGLKAVIAIHNSRLGPALGGCRYLAYPNDESAVEDAIRLA
CCCCHHHCCCCEEEEECCCHHHHEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHH
QGMSYKAALAGLAQGGGVAVIVRPAHVENRAALFEAFGRCIDQLDGRYITAIDSGTSVAD
HCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHH
MDCIAQQTQHVTSTTSAGDPAPHAAMGVFTGIRATAMARLGSDNLEGLRVAIQGLGNVGY
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHH
ALAEQLHAAGAELLVSDIDHGKVQLAMEQLNAHPIANDALLSTPCDILAPCGLGGVLNSH
HHHHHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHCCCHHHHCCCCCCCCCCCC
TVTQLRCSAVAGSANNQLTHLDVADQLERRGILYAPDYVINAGGLIYVSLKHRGEELTTI
HHHHHHHHHHCCCCCCCEEEECHHHHHHHCCCEECCCEEEECCCEEEEEEECCCCHHHHH
TAHLSKISSRLTEVFAHAQAEKRSPARVADELAEKVLYR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFALMQSTRLESLHLSVDPVSGLKAVIAIHNSRLGPALGGCRYLAYPNDESAVEDAIRLA
CCCCHHHCCCCEEEEECCCHHHHEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHH
QGMSYKAALAGLAQGGGVAVIVRPAHVENRAALFEAFGRCIDQLDGRYITAIDSGTSVAD
HCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHH
MDCIAQQTQHVTSTTSAGDPAPHAAMGVFTGIRATAMARLGSDNLEGLRVAIQGLGNVGY
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHH
ALAEQLHAAGAELLVSDIDHGKVQLAMEQLNAHPIANDALLSTPCDILAPCGLGGVLNSH
HHHHHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHCCCHHHHCCCCCCCCCCCC
TVTQLRCSAVAGSANNQLTHLDVADQLERRGILYAPDYVINAGGLIYVSLKHRGEELTTI
HHHHHHHHHHCCCCCCCEEEECHHHHHHHCCCEECCCEEEECCCEEEEEEECCCCHHHHH
TAHLSKISSRLTEVFAHAQAEKRSPARVADELAEKVLYR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3069133; 1400267 [H]