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The map label for this gene is mmgC [H]

Identifier: 73537997

GI number: 73537997

Start: 810346

End: 811485

Strand: Direct

Name: mmgC [H]

Synonym: Reut_B4166

Alternate gene names: 73537997

Gene position: 810346-811485 (Clockwise)

Preceding gene: 73537996

Following gene: 73537998

Centisome position: 29.72

GC content: 64.65

Gene sequence:

>1140_bases
ATGCAAATCACCCGTACGATCTACCGCGACGACCACGAAATGTTCCGCACCACGGTGCGCCGCTTCCTCGAAAAGGAATG
CGTGCCGAAGCAAGCCGAATGGGACAAGGCTGGCGTGGTCGACCGCGAAACCTGGCTCAAGGCCGGCCGTGAAGGCCTGC
TGTGCGTCACGCTGCCGACCGAATACGGTGGCGGTGGCGGCGACTTCGGCCACTCGGCCATCTACAACGAGGAGCTGGCG
CGCGCCGGCGTGAGCGGCCTGGGCTTCGGCGTCCATTCGGACATCATTGCCCCGTACATCAACCGCATCGGCAATGAAGA
GCAGAAGCAGCGCTGGCTGCCGAAGGTCTGCTCGGGCGAATACGTCCTGGCGATCGGCATGACCGAGCCGGGCACCGGCA
GCGACCTCAAGGCTATCCGCACCACGGCCGTCCGCGACGGCGACGAGTACGTGATCAACGGCAGCAAGACCTTCATCAGC
AATGGCCTGAACGCGGACCTGATCATCATGGTCTGCAAGACCGACCCGGCCGCCGGTGCGCGCGGTGTCAGCCTGATCGT
GGTCGAAGCCGACCGCGAAGGCTTCCGCCGTGGCCGCAAGCTCGACAAGGTCGGCCAGCACGCGCAGGACACCGCCGAGC
TGTTCTTCGACAACGTGCGCGTACCGGTCGGCAACCTGCTTGGCGAAGAAGGCAGAGGCTTTGCCTACCTGATGGGCGAA
CTGCCGCAGGAGCGCCTGTCGATCGCCATCAGCGCCGCCGCCAAGCTGGAAACGTGCCTGGAGCACACGCTCAACTACGT
GAAGGAGCGCAAGGCGTTCAACCAGACCGTGTGGGACTTCCAGAACACCAAGTTCAAGCTCGCCGACATCAAGGCCCAGG
CGATTGCCGTGCGCCTGATGGTGGATCACTACCTCGGCGAGCACATCCGCCGCCGCCTGACGCTCGAAGAAGCGGCCATT
GCCAAGCTCTACGCGACGGAGGCGCTGGGCAAGGCGCTCGACGAGATGGTGCAGCTGCACGGCGGCTACGGCTACATGAT
GGAGTACCCGGTGGCGCGTGCGTTTGCCGATTCGCGCGTGACGCGCATCTACGGCGGCACCAGCGAAGTCATGCGCGACC
TGATCTCGCGCAAGCTGTAA

Upstream 100 bases:

>100_bases
CGCGCGCGCGCCGGGCCAACCTTGTCGATGAACTGTTCCAACCCCAGCCCGCGCCCCACGTGGCCTGCGCATCCTGAACC
CGCTTCCACCGGAGCCTTCC

Downstream 100 bases:

>100_bases
GCGTCCCCAACAACAACCCGAAGAGATTCCAGGAGCCATTCAATGACCCGCAAAGTTTTCGTCGCCGGCGTCGGCATGAT
CCCGTTCAAGAAGCCCGGCA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MQITRTIYRDDHEMFRTTVRRFLEKECVPKQAEWDKAGVVDRETWLKAGREGLLCVTLPTEYGGGGGDFGHSAIYNEELA
RAGVSGLGFGVHSDIIAPYINRIGNEEQKQRWLPKVCSGEYVLAIGMTEPGTGSDLKAIRTTAVRDGDEYVINGSKTFIS
NGLNADLIIMVCKTDPAAGARGVSLIVVEADREGFRRGRKLDKVGQHAQDTAELFFDNVRVPVGNLLGEEGRGFAYLMGE
LPQERLSIAISAAAKLETCLEHTLNYVKERKAFNQTVWDFQNTKFKLADIKAQAIAVRLMVDHYLGEHIRRRLTLEEAAI
AKLYATEALGKALDEMVQLHGGYGYMMEYPVARAFADSRVTRIYGGTSEVMRDLISRKL

Sequences:

>Translated_379_residues
MQITRTIYRDDHEMFRTTVRRFLEKECVPKQAEWDKAGVVDRETWLKAGREGLLCVTLPTEYGGGGGDFGHSAIYNEELA
RAGVSGLGFGVHSDIIAPYINRIGNEEQKQRWLPKVCSGEYVLAIGMTEPGTGSDLKAIRTTAVRDGDEYVINGSKTFIS
NGLNADLIIMVCKTDPAAGARGVSLIVVEADREGFRRGRKLDKVGQHAQDTAELFFDNVRVPVGNLLGEEGRGFAYLMGE
LPQERLSIAISAAAKLETCLEHTLNYVKERKAFNQTVWDFQNTKFKLADIKAQAIAVRLMVDHYLGEHIRRRLTLEEAAI
AKLYATEALGKALDEMVQLHGGYGYMMEYPVARAFADSRVTRIYGGTSEVMRDLISRKL
>Mature_379_residues
MQITRTIYRDDHEMFRTTVRRFLEKECVPKQAEWDKAGVVDRETWLKAGREGLLCVTLPTEYGGGGGDFGHSAIYNEELA
RAGVSGLGFGVHSDIIAPYINRIGNEEQKQRWLPKVCSGEYVLAIGMTEPGTGSDLKAIRTTAVRDGDEYVINGSKTFIS
NGLNADLIIMVCKTDPAAGARGVSLIVVEADREGFRRGRKLDKVGQHAQDTAELFFDNVRVPVGNLLGEEGRGFAYLMGE
LPQERLSIAISAAAKLETCLEHTLNYVKERKAFNQTVWDFQNTKFKLADIKAQAIAVRLMVDHYLGEHIRRRLTLEEAAI
AKLYATEALGKALDEMVQLHGGYGYMMEYPVARAFADSRVTRIYGGTSEVMRDLISRKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=48.2758620689655, Blast_Score=368, Evalue=1e-102,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=35.656836461126, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=36.5781710914454, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI4557233, Length=380, Percent_Identity=35.7894736842105, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=31.3672922252011, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=33.6927223719677, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=31.3157894736842, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=31.3157894736842, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI76496475, Length=383, Percent_Identity=34.2036553524804, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI4557235, Length=383, Percent_Identity=34.2036553524804, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI21361497, Length=372, Percent_Identity=31.989247311828, Blast_Score=178, Evalue=8e-45,
Organism=Homo sapiens, GI38505218, Length=386, Percent_Identity=26.9430051813472, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=28.4210526315789, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI211971008, Length=395, Percent_Identity=26.0759493670886, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI48976061, Length=395, Percent_Identity=26.0759493670886, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7669494, Length=365, Percent_Identity=28.7671232876712, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI87081958, Length=351, Percent_Identity=28.7749287749288, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786223, Length=363, Percent_Identity=25.068870523416, Blast_Score=113, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=35.0267379679144, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=34.2245989304813, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17508101, Length=363, Percent_Identity=33.6088154269972, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17533517, Length=373, Percent_Identity=34.0482573726542, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=32.9815303430079, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17569725, Length=365, Percent_Identity=33.4246575342466, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17534899, Length=374, Percent_Identity=32.620320855615, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=31.4516129032258, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=31.2, Blast_Score=190, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=35.6115107913669, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI71985184, Length=342, Percent_Identity=33.6257309941521, Blast_Score=170, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI71982178, Length=263, Percent_Identity=32.319391634981, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=35.0877192982456, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=306, Percent_Identity=32.0261437908497, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=28.8702928870293, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=287, Percent_Identity=29.9651567944251, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17534353, Length=379, Percent_Identity=25.5936675461741, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=312, Percent_Identity=24.6794871794872, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86563383, Length=312, Percent_Identity=24.6794871794872, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=35.2, Blast_Score=224, Evalue=8e-59,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=31.3672922252011, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=31.7934782608696, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=33.6842105263158, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24646207, Length=369, Percent_Identity=33.3333333333333, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281363737, Length=372, Percent_Identity=31.7204301075269, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI19920834, Length=371, Percent_Identity=28.0323450134771, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42190; Mature: 42190

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQITRTIYRDDHEMFRTTVRRFLEKECVPKQAEWDKAGVVDRETWLKAGREGLLCVTLPT
CCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECC
EYGGGGGDFGHSAIYNEELARAGVSGLGFGVHSDIIAPYINRIGNEEQKQRWLPKVCSGE
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCHHHCCCC
YVLAIGMTEPGTGSDLKAIRTTAVRDGDEYVINGSKTFISNGLNADLIIMVCKTDPAAGA
EEEEEECCCCCCCCCHHHHHHHHHCCCCCEEECCCHHHHCCCCCCEEEEEEECCCCCCCC
RGVSLIVVEADREGFRRGRKLDKVGQHAQDTAELFFDNVRVPVGNLLGEEGRGFAYLMGE
CCEEEEEEECCHHHHHCCCHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEHHHH
LPQERLSIAISAAAKLETCLEHTLNYVKERKAFNQTVWDFQNTKFKLADIKAQAIAVRLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
VDHYLGEHIRRRLTLEEAAIAKLYATEALGKALDEMVQLHGGYGYMMEYPVARAFADSRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCH
TRIYGGTSEVMRDLISRKL
HEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MQITRTIYRDDHEMFRTTVRRFLEKECVPKQAEWDKAGVVDRETWLKAGREGLLCVTLPT
CCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECC
EYGGGGGDFGHSAIYNEELARAGVSGLGFGVHSDIIAPYINRIGNEEQKQRWLPKVCSGE
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCHHHCCCC
YVLAIGMTEPGTGSDLKAIRTTAVRDGDEYVINGSKTFISNGLNADLIIMVCKTDPAAGA
EEEEEECCCCCCCCCHHHHHHHHHCCCCCEEECCCHHHHCCCCCCEEEEEEECCCCCCCC
RGVSLIVVEADREGFRRGRKLDKVGQHAQDTAELFFDNVRVPVGNLLGEEGRGFAYLMGE
CCEEEEEEECCHHHHHCCCHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEHHHH
LPQERLSIAISAAAKLETCLEHTLNYVKERKAFNQTVWDFQNTKFKLADIKAQAIAVRLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
VDHYLGEHIRRRLTLEEAAIAKLYATEALGKALDEMVQLHGGYGYMMEYPVARAFADSRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCH
TRIYGGTSEVMRDLISRKL
HEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]