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The map label for this gene is paaJ [C]

Identifier: 73537998

GI number: 73537998

Start: 811528

End: 812718

Strand: Direct

Name: paaJ [C]

Synonym: Reut_B4167

Alternate gene names: 73537998

Gene position: 811528-812718 (Clockwise)

Preceding gene: 73537997

Following gene: 73537999

Centisome position: 29.77

GC content: 66.25

Gene sequence:

>1191_bases
ATGACCCGCAAAGTTTTCGTCGCCGGCGTCGGCATGATCCCGTTCAAGAAGCCCGGCACCAGCGAAACCTATGACGTGAT
GGGCGCACAGGCCGTGAAGCAGGCGCTGGAAGACGCCGGCTTGTCCTACGCCGACGTGCAGCAGGCTTACGCCGGCTACG
TCTACGGCGATTCCACGTGCGGCCAGAAGGCGCTGTACCACGTCGGCATGACTGGCATTCCGGTCATCAACGTCAACAAC
AACTGCGCTACCGGCTCGTCGGCGCTGTTCCTTGCCCGGCAGGCCGTGCAGAGCGGCGCAGTGGATTGCGCGCTCGCCGT
TGGCTTCGAGTTCATGAATCCCGGCGCGCTGAAGTCCGCCTGGACGGACCGCGCCAGCGCACTCGAGCGTGCCAACGACA
TCGTGGATGAACTCGTCGGCCGTCAGGAAGGCCTGAGCAATGCCATCCGCCAGTTCGCCGGCGCCGGCATGGCCCACATG
AAGAAGTACGGCACGAAGCTCGAGACCTTCGCGAAGATCCGCGCCAAGGCCAGCCACCACGCCGCGCGCAACCCGCTGGC
GGTGTTCCGCAACATCGTCTCGACCGAAGACGTCATGGCCGCGCCGATGCTGTGGGACGGCGTGCTGACGCGCCTGATGG
CCTGCCCGCCGACGTGCGGTGGTGCTGCTGCCATCGTGGTGTCCGAAGAGTTCGCCCGCAAGCGCGGCCTGCGCACCGAT
GTGCTGATCGCCGCGCAGGCGCTGACCACCGACACGCCGAGCACCTACGACGCGAAGGACATGATCCGCGTGGTCGGCTT
CGACATGACGCGCGCCGCCGCGGCCAGCGTTTACGAGCAGGCTGGCATCGGCCCGCGCGACATCGACGTGATCGAGCTGC
ACGACTGCTTCGCGCAGAATGAACTGCTGACCTATGAGGCACTTGGGCTATGCGACGAAGGTCACGGCGAGAAGCTGGTC
AACGACGGCGACAACAGCTATGGCGGCGAGTGGGTGGTCAATCCTTCGGGCGGCCTGCTGTCCAAGGGCCATCCGCTCGG
CGCCACCGGCCTCGCGCAGTGCTATGAGCTGACCCAGCAGATCCGCGGCACGGCCGAAGCGCGCCAGGTAGCAAACGCGA
AGATCGCGCTCGCGCATAACGTCGGCCTCGGTGGCGCCTGTGTCGTCACCGTCTACCAGAAGGCCGGCTGA

Upstream 100 bases:

>100_bases
GCGCATCTACGGCGGCACCAGCGAAGTCATGCGCGACCTGATCTCGCGCAAGCTGTAAGCGTCCCCAACAACAACCCGAA
GAGATTCCAGGAGCCATTCA

Downstream 100 bases:

>100_bases
CGGCTCACGAACCTCAAGAATCCCACGGAGGCATTCGACATGATCGACAAGAAACACATCGGCAAGGTGATCGCGGATTT
CCGCACCACCGCCCCGGCCA

Product: lipid-transfer protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTRKVFVAGVGMIPFKKPGTSETYDVMGAQAVKQALEDAGLSYADVQQAYAGYVYGDSTCGQKALYHVGMTGIPVINVNN
NCATGSSALFLARQAVQSGAVDCALAVGFEFMNPGALKSAWTDRASALERANDIVDELVGRQEGLSNAIRQFAGAGMAHM
KKYGTKLETFAKIRAKASHHAARNPLAVFRNIVSTEDVMAAPMLWDGVLTRLMACPPTCGGAAAIVVSEEFARKRGLRTD
VLIAAQALTTDTPSTYDAKDMIRVVGFDMTRAAAASVYEQAGIGPRDIDVIELHDCFAQNELLTYEALGLCDEGHGEKLV
NDGDNSYGGEWVVNPSGGLLSKGHPLGATGLAQCYELTQQIRGTAEARQVANAKIALAHNVGLGGACVVTVYQKAG

Sequences:

>Translated_396_residues
MTRKVFVAGVGMIPFKKPGTSETYDVMGAQAVKQALEDAGLSYADVQQAYAGYVYGDSTCGQKALYHVGMTGIPVINVNN
NCATGSSALFLARQAVQSGAVDCALAVGFEFMNPGALKSAWTDRASALERANDIVDELVGRQEGLSNAIRQFAGAGMAHM
KKYGTKLETFAKIRAKASHHAARNPLAVFRNIVSTEDVMAAPMLWDGVLTRLMACPPTCGGAAAIVVSEEFARKRGLRTD
VLIAAQALTTDTPSTYDAKDMIRVVGFDMTRAAAASVYEQAGIGPRDIDVIELHDCFAQNELLTYEALGLCDEGHGEKLV
NDGDNSYGGEWVVNPSGGLLSKGHPLGATGLAQCYELTQQIRGTAEARQVANAKIALAHNVGLGGACVVTVYQKAG
>Mature_395_residues
TRKVFVAGVGMIPFKKPGTSETYDVMGAQAVKQALEDAGLSYADVQQAYAGYVYGDSTCGQKALYHVGMTGIPVINVNNN
CATGSSALFLARQAVQSGAVDCALAVGFEFMNPGALKSAWTDRASALERANDIVDELVGRQEGLSNAIRQFAGAGMAHMK
KYGTKLETFAKIRAKASHHAARNPLAVFRNIVSTEDVMAAPMLWDGVLTRLMACPPTCGGAAAIVVSEEFARKRGLRTDV
LIAAQALTTDTPSTYDAKDMIRVVGFDMTRAAAASVYEQAGIGPRDIDVIELHDCFAQNELLTYEALGLCDEGHGEKLVN
DGDNSYGGEWVVNPSGGLLSKGHPLGATGLAQCYELTQQIRGTAEARQVANAKIALAHNVGLGGACVVTVYQKAG

Specific function: Thiolytic Cleavage Of Beta-Ketoadipyl-CoA To Succinate And Acetyl-CoA (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=398, Percent_Identity=55.5276381909548, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI302344760, Length=396, Percent_Identity=52.7777777777778, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI302344767, Length=328, Percent_Identity=55.7926829268293, Blast_Score=351, Evalue=6e-97,
Organism=Homo sapiens, GI302344762, Length=397, Percent_Identity=47.103274559194, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI55956775, Length=358, Percent_Identity=44.9720670391061, Blast_Score=271, Evalue=1e-72,
Organism=Escherichia coli, GI1787663, Length=322, Percent_Identity=27.3291925465839, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17537653, Length=385, Percent_Identity=45.7142857142857, Blast_Score=343, Evalue=8e-95,
Organism=Drosophila melanogaster, GI24585051, Length=393, Percent_Identity=53.4351145038168, Blast_Score=424, Evalue=1e-119,
Organism=Drosophila melanogaster, GI19921506, Length=397, Percent_Identity=52.6448362720403, Blast_Score=420, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 41804; Mature: 41673

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKVFVAGVGMIPFKKPGTSETYDVMGAQAVKQALEDAGLSYADVQQAYAGYVYGDSTC
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCEEECCCCC
GQKALYHVGMTGIPVINVNNNCATGSSALFLARQAVQSGAVDCALAVGFEFMNPGALKSA
HHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCHHHCCCCHHHHH
WTDRASALERANDIVDELVGRQEGLSNAIRQFAGAGMAHMKKYGTKLETFAKIRAKASHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHH
AARNPLAVFRNIVSTEDVMAAPMLWDGVLTRLMACPPTCGGAAAIVVSEEFARKRGLRTD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCHH
VLIAAQALTTDTPSTYDAKDMIRVVGFDMTRAAAASVYEQAGIGPRDIDVIELHDCFAQN
HHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCC
ELLTYEALGLCDEGHGEKLVNDGDNSYGGEWVVNPSGGLLSKGHPLGATGLAQCYELTQQ
CEEEHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
IRGTAEARQVANAKIALAHNVGLGGACVVTVYQKAG
HHCHHHHHHHHCCEEEEEECCCCCCEEEEEEEECCC
>Mature Secondary Structure 
TRKVFVAGVGMIPFKKPGTSETYDVMGAQAVKQALEDAGLSYADVQQAYAGYVYGDSTC
CCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCEEECCCCC
GQKALYHVGMTGIPVINVNNNCATGSSALFLARQAVQSGAVDCALAVGFEFMNPGALKSA
HHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCHHHCCCCHHHHH
WTDRASALERANDIVDELVGRQEGLSNAIRQFAGAGMAHMKKYGTKLETFAKIRAKASHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHH
AARNPLAVFRNIVSTEDVMAAPMLWDGVLTRLMACPPTCGGAAAIVVSEEFARKRGLRTD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCHH
VLIAAQALTTDTPSTYDAKDMIRVVGFDMTRAAAASVYEQAGIGPRDIDVIELHDCFAQN
HHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCC
ELLTYEALGLCDEGHGEKLVNDGDNSYGGEWVVNPSGGLLSKGHPLGATGLAQCYELTQQ
CEEEHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
IRGTAEARQVANAKIALAHNVGLGGACVVTVYQKAG
HHCHHHHHHHHCCEEEEEECCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]