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The map label for this gene is frc [H]

Identifier: 73537659

GI number: 73537659

Start: 429880

End: 431151

Strand: Reverse

Name: frc [H]

Synonym: Reut_B3824

Alternate gene names: 73537659

Gene position: 431151-429880 (Counterclockwise)

Preceding gene: 73537660

Following gene: 73537658

Centisome position: 15.82

GC content: 66.04

Gene sequence:

>1272_bases
ATGCGATGCTGGGCAAGATCGCGGCCTGAACGGGAGCCCGAAGTGCAGAGTCAAGCCAAACCCGCCGGGGCGCTTGCCGG
CCTGCGCGTGATCGACCTCACGCAGATGCTGGCCGGCCCCTTTTGCACGCAGATCCTCGCTGACCACGGGGCGGATGTCA
TCAAGGTCGAAGCGATGACGGGCGACGGCACGCGTGTGACCGGCCCGTTCTGCCCCGACGACGCGCTGCGCGACTTCGGC
GGCTATTTCCAGAGCGTCAACCGCAACAAGCGCTCCATCGCCGTCGACCTGAAGACGGAGGCGGGTCGTGCAGTCCTGCG
CGCGCTGATCGACAAGGCCGACATCGTCGTCGAAAACTTCCGAGCAGGCGTGATGGAGCGCCTGGGCTTTGCCTACGAAA
CGCTGCGCCAGACCAACCCGCGGCTGATCTACGGCACGGTGCGCGGCTTTGGCGATCCGCGGAGCGGCGAAAGCCCGTAT
GCGCAATGGCCGGCGTACGACGTGGTTTCGCAGGCTATGGGCGGCATGATGGGCATCACCGGCCCGGATCGTTGCACACC
GACCAAGATCGGTCCCGGCGTGGGGGACACCATTCCGGCGCTGATGCTGTGCATCGGCATCCTCGCGGCCGTCAATCGCG
TGCGCGAAACCGGTCAGGGCCAGTTCGTCGACGTGGCCATGACCGACGCGGTGCTGGCCATGTGCGAGCGCATCGTCTAC
CAGAACTCGTACACCGGCGAAGTGGCCGCACCGGAAGGCAACCGCCACCCGCTGCTGTGCCCGTTCGGCTTGTTCCGTGC
GCGCGATGGCCATGTCTCGATTGCCTGCGCGACCGATGCGTTCTGGGAAAAGCTCGCCGTGGCGATCGGCCGCCCCGACA
TGGCGCAGGACCCGGACTTCGCGACCAATGCCGCGCGCGTGCAGCATCAGCAGCAGGTGATCGAGGCGATCGAAGCCTTT
ACCTCGGTGCGAACCAAGGAAGAGATTGCCATCGCGCTGGGCGGCAAGGTTCCCTTCGGCCCCGTCTATACCTCGGCCGA
GATATTCGCGGACAGGCACTACGCGGTGCGCGACATGATCGTCGAAGTGGAGCAACCGGGATCGGCCACTCCGGTCAAGA
TCGCCGGCGTACCGATCAAGCTCAGCGAAACCCCGGGCGCGGTGCGCACGCGCGCGCCAATGCTGGGCGAGCACACCGAA
GAGATTTTGTTCGGTGCCGGCTATGTGGAGGACGATATTCGCCGTCTGCGGCAGGAGGGCGCGGTGCGGTAA

Upstream 100 bases:

>100_bases
GGCTACACCACGCACTTCGCGGCCGAACGCTACTGGCGCGATGCGCGCCTGACCAAGATCTTCGAAGGTACCTCTGAAAT
CCAGATGCGCATCATCTCCG

Downstream 100 bases:

>100_bases
GGCAGCACTGAAGTGAAAGCGGCGCTGCGGGCGGTCTGACGGGTTGTTGCAGCCGGGAGGCCGCCGGCAACTCAGTCCCG
TGGCTGTGGAGCGTTTAAGG

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MRCWARSRPEREPEVQSQAKPAGALAGLRVIDLTQMLAGPFCTQILADHGADVIKVEAMTGDGTRVTGPFCPDDALRDFG
GYFQSVNRNKRSIAVDLKTEAGRAVLRALIDKADIVVENFRAGVMERLGFAYETLRQTNPRLIYGTVRGFGDPRSGESPY
AQWPAYDVVSQAMGGMMGITGPDRCTPTKIGPGVGDTIPALMLCIGILAAVNRVRETGQGQFVDVAMTDAVLAMCERIVY
QNSYTGEVAAPEGNRHPLLCPFGLFRARDGHVSIACATDAFWEKLAVAIGRPDMAQDPDFATNAARVQHQQQVIEAIEAF
TSVRTKEEIAIALGGKVPFGPVYTSAEIFADRHYAVRDMIVEVEQPGSATPVKIAGVPIKLSETPGAVRTRAPMLGEHTE
EILFGAGYVEDDIRRLRQEGAVR

Sequences:

>Translated_423_residues
MRCWARSRPEREPEVQSQAKPAGALAGLRVIDLTQMLAGPFCTQILADHGADVIKVEAMTGDGTRVTGPFCPDDALRDFG
GYFQSVNRNKRSIAVDLKTEAGRAVLRALIDKADIVVENFRAGVMERLGFAYETLRQTNPRLIYGTVRGFGDPRSGESPY
AQWPAYDVVSQAMGGMMGITGPDRCTPTKIGPGVGDTIPALMLCIGILAAVNRVRETGQGQFVDVAMTDAVLAMCERIVY
QNSYTGEVAAPEGNRHPLLCPFGLFRARDGHVSIACATDAFWEKLAVAIGRPDMAQDPDFATNAARVQHQQQVIEAIEAF
TSVRTKEEIAIALGGKVPFGPVYTSAEIFADRHYAVRDMIVEVEQPGSATPVKIAGVPIKLSETPGAVRTRAPMLGEHTE
EILFGAGYVEDDIRRLRQEGAVR
>Mature_423_residues
MRCWARSRPEREPEVQSQAKPAGALAGLRVIDLTQMLAGPFCTQILADHGADVIKVEAMTGDGTRVTGPFCPDDALRDFG
GYFQSVNRNKRSIAVDLKTEAGRAVLRALIDKADIVVENFRAGVMERLGFAYETLRQTNPRLIYGTVRGFGDPRSGESPY
AQWPAYDVVSQAMGGMMGITGPDRCTPTKIGPGVGDTIPALMLCIGILAAVNRVRETGQGQFVDVAMTDAVLAMCERIVY
QNSYTGEVAAPEGNRHPLLCPFGLFRARDGHVSIACATDAFWEKLAVAIGRPDMAQDPDFATNAARVQHQQQVIEAIEAF
TSVRTKEEIAIALGGKVPFGPVYTSAEIFADRHYAVRDMIVEVEQPGSATPVKIAGVPIKLSETPGAVRTRAPMLGEHTE
EILFGAGYVEDDIRRLRQEGAVR

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=392, Percent_Identity=30.1020408163265, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI300863124, Length=418, Percent_Identity=28.7081339712919, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI300863126, Length=392, Percent_Identity=27.5510204081633, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI13376042, Length=418, Percent_Identity=26.3157894736842, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI266456254, Length=405, Percent_Identity=28.8888888888889, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI42794625, Length=405, Percent_Identity=28.8888888888889, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI266458393, Length=271, Percent_Identity=30.9963099630996, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI266458397, Length=269, Percent_Identity=31.2267657992565, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI266458395, Length=152, Percent_Identity=37.5, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI42822893, Length=152, Percent_Identity=36.8421052631579, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI87082093, Length=359, Percent_Identity=35.933147632312, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1788717, Length=425, Percent_Identity=34.5882352941176, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1786222, Length=408, Percent_Identity=26.4705882352941, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32564160, Length=270, Percent_Identity=24.0740740740741, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648431, Length=402, Percent_Identity=34.0796019900498, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24585488, Length=374, Percent_Identity=25.668449197861, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 45851; Mature: 45851

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCWARSRPEREPEVQSQAKPAGALAGLRVIDLTQMLAGPFCTQILADHGADVIKVEAMT
CCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
GDGTRVTGPFCPDDALRDFGGYFQSVNRNKRSIAVDLKTEAGRAVLRALIDKADIVVENF
CCCCEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
RAGVMERLGFAYETLRQTNPRLIYGTVRGFGDPRSGESPYAQWPAYDVVSQAMGGMMGIT
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCEECCC
GPDRCTPTKIGPGVGDTIPALMLCIGILAAVNRVRETGQGQFVDVAMTDAVLAMCERIVY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
QNSYTGEVAAPEGNRHPLLCPFGLFRARDGHVSIACATDAFWEKLAVAIGRPDMAQDPDF
CCCCCCCEECCCCCCCCEECCHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCC
ATNAARVQHQQQVIEAIEAFTSVRTKEEIAIALGGKVPFGPVYTSAEIFADRHYAVRDMI
CHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
VEVEQPGSATPVKIAGVPIKLSETPGAVRTRAPMLGEHTEEILFGAGYVEDDIRRLRQEG
HEECCCCCCCCEEEECEEEEECCCCCCHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHC
AVR
CCC
>Mature Secondary Structure
MRCWARSRPEREPEVQSQAKPAGALAGLRVIDLTQMLAGPFCTQILADHGADVIKVEAMT
CCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
GDGTRVTGPFCPDDALRDFGGYFQSVNRNKRSIAVDLKTEAGRAVLRALIDKADIVVENF
CCCCEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
RAGVMERLGFAYETLRQTNPRLIYGTVRGFGDPRSGESPYAQWPAYDVVSQAMGGMMGIT
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCEECCC
GPDRCTPTKIGPGVGDTIPALMLCIGILAAVNRVRETGQGQFVDVAMTDAVLAMCERIVY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
QNSYTGEVAAPEGNRHPLLCPFGLFRARDGHVSIACATDAFWEKLAVAIGRPDMAQDPDF
CCCCCCCEECCCCCCCCEECCHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCC
ATNAARVQHQQQVIEAIEAFTSVRTKEEIAIALGGKVPFGPVYTSAEIFADRHYAVRDMI
CHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
VEVEQPGSATPVKIAGVPIKLSETPGAVRTRAPMLGEHTEEILFGAGYVEDDIRRLRQEG
HEECCCCCCCCEEEECEEEEECCCCCCHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHC
AVR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]