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The map label for this gene is acdA [H]

Identifier: 73537660

GI number: 73537660

Start: 431123

End: 432325

Strand: Reverse

Name: acdA [H]

Synonym: Reut_B3825

Alternate gene names: 73537660

Gene position: 432325-431123 (Counterclockwise)

Preceding gene: 73537662

Following gene: 73537659

Centisome position: 15.86

GC content: 64.51

Gene sequence:

>1203_bases
ATGGGCAACCAGAGACCGGAGACGGAAGGAGCAAAGGTGCAGAAACTGACCGAAGAACGCCGCATGATCCAGGAGGCCGC
GCGCCAGTTCACGATGGAGCGCGTGCTGCCCATCGCCAACAAGCTGGACCCCGAGAAAGGCAAGATCCCGCGCGAGCTGA
TCGACGAGATGGCCGAACTCGGCTACTTCGGCATCCTGATTCCCGAGGAATACGGCGGCCTGGGCCTTGGCGCCTATGAG
TACTGCCTGGTCGCCGAGCAGCTTTCGCGTGGCTGGATGAGCGTCGGCAGCCTGATCGCACGCGGCAATGGCCTGATCGG
CGCGCTCAAGGGCCTGTCGCCAGAGCGCAAGGCCGAATACCTGCCGCGCATGGCGCGCGGTGAATTCCTCGGCGCGTTCT
CGCTGTCCGAGCCCAATGCCGGCTCCGACGTGGCCAATATCTCGTGCCGCGCGGTGCGCGATGGCGACGACTGGCTCATC
ACCGGCAGCAAGTACTGGTGCACGTTTGCCGACGAGGCCGACTTCATCCTGGTCATCTGCCGTACCGATCCGGTCATCGA
CCCGAAGGCGCGCCACAAGGGCCTGTCGGCCTTCATGGTGGAAAAGCCCCGCGGCGAACTCCCCGAGGGCGTCAAGGGCA
GCGTGATTCCCAAGATCGGCTACCACGGCTGGACCACGTGGGAACTCGCGTTCGACGGCTGCCGTGTGCCGCATTCGAAG
ATGGTCGGTGAGGAAGGCAAGGCGTTCTACCTGACCACCGCCGGCCTCGAAACCGCGCGTGCTCACACGGCCGCGCGTTC
GATCGGGCTTGCACAGGGCAGCCTCGAGGACTCGATCCAATACGCCAAGGACCGCAACCAGTTCGGCAACCCGATCGGCA
ACTTCCAGGCGATTCGCTTCAAGCTCGCCGACATGGCCACGCAGATCGAAGCCTCGCGCGCGCTGCTCTACACCGTGTGC
GAAAGGATCGACGAAGGCGTGCGCGCCGACACCGAAGCGTCGATGGTCAAGCTGTTTGCGAGCGAGATGTGCGAGCGCGT
GACCAGCGAAGGCCTGCAGATCCACGGCGGCGCGGGCTACACCACGCACTTCGCGGCCGAACGCTACTGGCGCGATGCGC
GCCTGACCAAGATCTTCGAAGGTACCTCTGAAATCCAGATGCGCATCATCTCCGATGCGATGCTGGGCAAGATCGCGGCC
TGA

Upstream 100 bases:

>100_bases
AATGGAACTTAACCCACAAAAAAGTTGCGTGCGCCTTCAAGGTTTCTTGCAAATTCCCTTTAATCCACTCCATACTATGT
ACGTACATAGTGCCAGAACA

Downstream 100 bases:

>100_bases
ACGGGAGCCCGAAGTGCAGAGTCAAGCCAAACCCGCCGGGGCGCTTGCCGGCCTGCGCGTGATCGACCTCACGCAGATGC
TGGCCGGCCCCTTTTGCACG

Product: butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MGNQRPETEGAKVQKLTEERRMIQEAARQFTMERVLPIANKLDPEKGKIPRELIDEMAELGYFGILIPEEYGGLGLGAYE
YCLVAEQLSRGWMSVGSLIARGNGLIGALKGLSPERKAEYLPRMARGEFLGAFSLSEPNAGSDVANISCRAVRDGDDWLI
TGSKYWCTFADEADFILVICRTDPVIDPKARHKGLSAFMVEKPRGELPEGVKGSVIPKIGYHGWTTWELAFDGCRVPHSK
MVGEEGKAFYLTTAGLETARAHTAARSIGLAQGSLEDSIQYAKDRNQFGNPIGNFQAIRFKLADMATQIEASRALLYTVC
ERIDEGVRADTEASMVKLFASEMCERVTSEGLQIHGGAGYTTHFAAERYWRDARLTKIFEGTSEIQMRIISDAMLGKIAA

Sequences:

>Translated_400_residues
MGNQRPETEGAKVQKLTEERRMIQEAARQFTMERVLPIANKLDPEKGKIPRELIDEMAELGYFGILIPEEYGGLGLGAYE
YCLVAEQLSRGWMSVGSLIARGNGLIGALKGLSPERKAEYLPRMARGEFLGAFSLSEPNAGSDVANISCRAVRDGDDWLI
TGSKYWCTFADEADFILVICRTDPVIDPKARHKGLSAFMVEKPRGELPEGVKGSVIPKIGYHGWTTWELAFDGCRVPHSK
MVGEEGKAFYLTTAGLETARAHTAARSIGLAQGSLEDSIQYAKDRNQFGNPIGNFQAIRFKLADMATQIEASRALLYTVC
ERIDEGVRADTEASMVKLFASEMCERVTSEGLQIHGGAGYTTHFAAERYWRDARLTKIFEGTSEIQMRIISDAMLGKIAA
>Mature_399_residues
GNQRPETEGAKVQKLTEERRMIQEAARQFTMERVLPIANKLDPEKGKIPRELIDEMAELGYFGILIPEEYGGLGLGAYEY
CLVAEQLSRGWMSVGSLIARGNGLIGALKGLSPERKAEYLPRMARGEFLGAFSLSEPNAGSDVANISCRAVRDGDDWLIT
GSKYWCTFADEADFILVICRTDPVIDPKARHKGLSAFMVEKPRGELPEGVKGSVIPKIGYHGWTTWELAFDGCRVPHSKM
VGEEGKAFYLTTAGLETARAHTAARSIGLAQGSLEDSIQYAKDRNQFGNPIGNFQAIRFKLADMATQIEASRALLYTVCE
RIDEGVRADTEASMVKLFASEMCERVTSEGLQIHGGAGYTTHFAAERYWRDARLTKIFEGTSEIQMRIISDAMLGKIAA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=37.3368146214099, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI226958412, Length=385, Percent_Identity=35.8441558441558, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI4501859, Length=383, Percent_Identity=34.7258485639687, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI226958414, Length=362, Percent_Identity=35.6353591160221, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI4557231, Length=386, Percent_Identity=33.6787564766839, Blast_Score=221, Evalue=9e-58,
Organism=Homo sapiens, GI187960098, Length=386, Percent_Identity=33.6787564766839, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI21361497, Length=352, Percent_Identity=35.5113636363636, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI7656849, Length=383, Percent_Identity=31.8537859007833, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI76496475, Length=380, Percent_Identity=34.2105263157895, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI4557235, Length=380, Percent_Identity=34.2105263157895, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI4501857, Length=401, Percent_Identity=31.1720698254364, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI4503943, Length=406, Percent_Identity=29.3103448275862, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI7669494, Length=390, Percent_Identity=28.974358974359, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI38505218, Length=393, Percent_Identity=24.6819338422392, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI211971008, Length=396, Percent_Identity=24.4949494949495, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI48976061, Length=396, Percent_Identity=24.4949494949495, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=30.7086614173228, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786223, Length=346, Percent_Identity=27.1676300578035, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082384, Length=288, Percent_Identity=27.4305555555556, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=35.0785340314136, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17569725, Length=392, Percent_Identity=33.1632653061224, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=32.8165374677003, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17534899, Length=388, Percent_Identity=32.9896907216495, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17508101, Length=382, Percent_Identity=34.2931937172775, Blast_Score=221, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI17506239, Length=381, Percent_Identity=33.3333333333333, Blast_Score=214, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17533517, Length=380, Percent_Identity=33.1578947368421, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI71985184, Length=362, Percent_Identity=30.6629834254144, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI71990804, Length=295, Percent_Identity=35.9322033898305, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17505929, Length=414, Percent_Identity=31.4009661835749, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17551932, Length=395, Percent_Identity=31.1392405063291, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71985192, Length=304, Percent_Identity=29.6052631578947, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71982178, Length=286, Percent_Identity=29.7202797202797, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32563615, Length=237, Percent_Identity=34.1772151898734, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17534353, Length=399, Percent_Identity=27.0676691729323, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=29.3388429752066, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=368, Percent_Identity=26.6304347826087, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17531913, Length=173, Percent_Identity=28.3236994219653, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=269, Percent_Identity=27.1375464684015, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI86563383, Length=269, Percent_Identity=27.1375464684015, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356377, Length=392, Percent_Identity=36.9897959183673, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24660351, Length=381, Percent_Identity=36.4829396325459, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24666513, Length=387, Percent_Identity=32.8165374677003, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24646207, Length=381, Percent_Identity=35.1706036745407, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI21355753, Length=378, Percent_Identity=34.9206349206349, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI281363737, Length=334, Percent_Identity=34.1317365269461, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI19920834, Length=395, Percent_Identity=28.1012658227848, Blast_Score=123, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44122; Mature: 43991

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNQRPETEGAKVQKLTEERRMIQEAARQFTMERVLPIANKLDPEKGKIPRELIDEMAEL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
GYFGILIPEEYGGLGLGAYEYCLVAEQLSRGWMSVGSLIARGNGLIGALKGLSPERKAEY
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCHHHHHHH
LPRMARGEFLGAFSLSEPNAGSDVANISCRAVRDGDDWLITGSKYWCTFADEADFILVIC
CCHHHCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCEEEECCEEEEEECCCCCEEEEEE
RTDPVIDPKARHKGLSAFMVEKPRGELPEGVKGSVIPKIGYHGWTTWELAFDGCRVPHSK
CCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHH
MVGEEGKAFYLTTAGLETARAHTAARSIGLAQGSLEDSIQYAKDRNQFGNPIGNFQAIRF
HCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
KLADMATQIEASRALLYTVCERIDEGVRADTEASMVKLFASEMCERVTSEGLQIHGGAGY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
TTHFAAERYWRDARLTKIFEGTSEIQMRIISDAMLGKIAA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GNQRPETEGAKVQKLTEERRMIQEAARQFTMERVLPIANKLDPEKGKIPRELIDEMAEL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
GYFGILIPEEYGGLGLGAYEYCLVAEQLSRGWMSVGSLIARGNGLIGALKGLSPERKAEY
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCHHHHHHH
LPRMARGEFLGAFSLSEPNAGSDVANISCRAVRDGDDWLITGSKYWCTFADEADFILVIC
CCHHHCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCEEEECCEEEEEECCCCCEEEEEE
RTDPVIDPKARHKGLSAFMVEKPRGELPEGVKGSVIPKIGYHGWTTWELAFDGCRVPHSK
CCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHH
MVGEEGKAFYLTTAGLETARAHTAARSIGLAQGSLEDSIQYAKDRNQFGNPIGNFQAIRF
HCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
KLADMATQIEASRALLYTVCERIDEGVRADTEASMVKLFASEMCERVTSEGLQIHGGAGY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
TTHFAAERYWRDARLTKIFEGTSEIQMRIISDAMLGKIAA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]