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The map label for this gene is queD [H]

Identifier: 73541536

GI number: 73541536

Start: 2022743

End: 2023219

Strand: Reverse

Name: queD [H]

Synonym: Reut_A1847

Alternate gene names: 73541536

Gene position: 2023219-2022743 (Counterclockwise)

Preceding gene: 73541537

Following gene: 73541535

Centisome position: 53.15

GC content: 61.22

Gene sequence:

>477_bases
ATGAGCAAACAAGTTTCCATTACCCGCCGGCTGGAATTCGATTCCGGCCACCGCATCCCGAACCACTGCGGCCAATGCCG
CAATATCCACGGCCACCGCTATCGCCTGGACCTGACGCTGTCGGGCGAAGTGCTGCACCGTGAAGGCGCGTCCGACGACG
GCATGATTCTGGACTTCGGCGATATCAAGTCGCTGGCGCAGGAGCATCTGGTGTCGAAGTGGGACCATGCGTTCCTGATC
TATCGCGGCGACACCGCGCTGCTGAACTTTCTGCAATCGATGGAAGGGCACAAGACTGTGGTGCTTGATGCCATTCCGAC
CGTCGAGAACCTCGCGCAGATCGCCTTCGACATGCTGGCGCCCGTGTTCAAGGACTGCTTCGGCCATCATCTGCAGCTGA
CCCGCCTGGTCCTGTTCGAAACGCCGAATTGCTGGGCGGAAGTCACCGCCACGGTCGCGCTGCCGGCGCAGGACTGA

Upstream 100 bases:

>100_bases
GCTGATTGCTGTCGCGCAGGTCGCACCTCGGCGACAATAGCGCCGCGGACCCCGGCACGAAGCCCATTCAACGCAGGCCG
CCTAGCATGCGCCCGTACTC

Downstream 100 bases:

>100_bases
GCCGGCGATGACGGATACCCGCACCGCGGACGAGATCGCGCGCGACGAGCGCTACCTGCGCGCCGCCATGGACGAGGCCC
GTCTGGCCGAGGCCGCGGGC

Product: putative 6-pyruvoyl tetrahydrobiopterin synthase protein

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSKQVSITRRLEFDSGHRIPNHCGQCRNIHGHRYRLDLTLSGEVLHREGASDDGMILDFGDIKSLAQEHLVSKWDHAFLI
YRGDTALLNFLQSMEGHKTVVLDAIPTVENLAQIAFDMLAPVFKDCFGHHLQLTRLVLFETPNCWAEVTATVALPAQD

Sequences:

>Translated_158_residues
MSKQVSITRRLEFDSGHRIPNHCGQCRNIHGHRYRLDLTLSGEVLHREGASDDGMILDFGDIKSLAQEHLVSKWDHAFLI
YRGDTALLNFLQSMEGHKTVVLDAIPTVENLAQIAFDMLAPVFKDCFGHHLQLTRLVLFETPNCWAEVTATVALPAQD
>Mature_157_residues
SKQVSITRRLEFDSGHRIPNHCGQCRNIHGHRYRLDLTLSGEVLHREGASDDGMILDFGDIKSLAQEHLVSKWDHAFLIY
RGDTALLNFLQSMEGHKTVVLDAIPTVENLAQIAFDMLAPVFKDCFGHHLQLTRLVLFETPNCWAEVTATVALPAQD

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 17807; Mature: 17675

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQVSITRRLEFDSGHRIPNHCGQCRNIHGHRYRLDLTLSGEVLHREGASDDGMILDFG
CCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCEEEEEEEECCCEEECCCCCCCCEEEEHH
DIKSLAQEHLVSKWDHAFLIYRGDTALLNFLQSMEGHKTVVLDAIPTVENLAQIAFDMLA
HHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
PVFKDCFGHHLQLTRLVLFETPNCWAEVTATVALPAQD
HHHHHHHCCHHEEEEEEEEECCCCCEEEEEEEEECCCC
>Mature Secondary Structure 
SKQVSITRRLEFDSGHRIPNHCGQCRNIHGHRYRLDLTLSGEVLHREGASDDGMILDFG
CCCCEEEEEEECCCCCCCCHHHHHHCCCCCCEEEEEEEECCCEEECCCCCCCCEEEEHH
DIKSLAQEHLVSKWDHAFLIYRGDTALLNFLQSMEGHKTVVLDAIPTVENLAQIAFDMLA
HHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
PVFKDCFGHHLQLTRLVLFETPNCWAEVTATVALPAQD
HHHHHHHCCHHEEEEEEEEECCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA