Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 73541535

GI number: 73541535

Start: 2022202

End: 2022735

Strand: Reverse

Name: tadA [H]

Synonym: Reut_A1846

Alternate gene names: 73541535

Gene position: 2022735-2022202 (Counterclockwise)

Preceding gene: 73541536

Following gene: 73541534

Centisome position: 53.14

GC content: 68.16

Gene sequence:

>534_bases
ATGACGGATACCCGCACCGCGGACGAGATCGCGCGCGACGAGCGCTACCTGCGCGCCGCCATGGACGAGGCCCGTCTGGC
CGAGGCCGCGGGCGAGGTGCCGGTCGGTGCGGTGGTGGTGTGGAACGACGCCATCATCGCGCGCGGCCACAACCTGCCGA
TCAAGTCGATGGATCCGTCAGCCCATGCCGAAATGCAGGCGCTGCGCGCCGCGGCCCAGGTGCTCGGCAACTACCGCATG
CCGGAGTGCGAACTGTATGTGACGCTGGAACCTTGCGCGATGTGCAGCGGCGCGATCCTCCATGCGCGCCTGCGCCATGT
GGTGTTCGGTGCGTCGGACCCGAAGACCGGCGCCGCCGGTAGCGTAGTGAACCTGTTCGAGCAGGCACAACTGAACCACC
AGACCACCATTACGGGCGGAGTGCTCGCGGACGAGTGCGGGCAGATGCTGAAGGACTTCTTCGGTGCCCGGCGCCGCGCG
CAGAAGGCGGCGCAACTCGCTGCCCGGACGCTGTCCGATCCCGAACAATCCTGA

Upstream 100 bases:

>100_bases
CATCATCTGCAGCTGACCCGCCTGGTCCTGTTCGAAACGCCGAATTGCTGGGCGGAAGTCACCGCCACGGTCGCGCTGCC
GGCGCAGGACTGAGCCGGCG

Downstream 100 bases:

>100_bases
TCCCCCGGACGATCACGAATCCGCATGAGCACACCGAGCCCCAAGCCGCATACCGAAGTTCGCCTGATCGCGTCGTCCGG
CTACCCGCACGATGTCGCCA

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MTDTRTADEIARDERYLRAAMDEARLAEAAGEVPVGAVVVWNDAIIARGHNLPIKSMDPSAHAEMQALRAAAQVLGNYRM
PECELYVTLEPCAMCSGAILHARLRHVVFGASDPKTGAAGSVVNLFEQAQLNHQTTITGGVLADECGQMLKDFFGARRRA
QKAAQLAARTLSDPEQS

Sequences:

>Translated_177_residues
MTDTRTADEIARDERYLRAAMDEARLAEAAGEVPVGAVVVWNDAIIARGHNLPIKSMDPSAHAEMQALRAAAQVLGNYRM
PECELYVTLEPCAMCSGAILHARLRHVVFGASDPKTGAAGSVVNLFEQAQLNHQTTITGGVLADECGQMLKDFFGARRRA
QKAAQLAARTLSDPEQS
>Mature_176_residues
TDTRTADEIARDERYLRAAMDEARLAEAAGEVPVGAVVVWNDAIIARGHNLPIKSMDPSAHAEMQALRAAAQVLGNYRMP
ECELYVTLEPCAMCSGAILHARLRHVVFGASDPKTGAAGSVVNLFEQAQLNHQTTITGGVLADECGQMLKDFFGARRRAQ
KAAQLAARTLSDPEQS

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=152, Percent_Identity=32.2368421052632, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI145693172, Length=155, Percent_Identity=51.6129032258064, Blast_Score=162, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17541138, Length=147, Percent_Identity=35.3741496598639, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=99, Percent_Identity=35.3535353535354, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=100, Percent_Identity=37, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=36.551724137931, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19076; Mature: 18945

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTRTADEIARDERYLRAAMDEARLAEAAGEVPVGAVVVWNDAIIARGHNLPIKSMDPS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEECCCCCCCCCCCCH
AHAEMQALRAAAQVLGNYRMPECELYVTLEPCAMCSGAILHARLRHVVFGASDPKTGAAG
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
SVVNLFEQAQLNHQTTITGGVLADECGQMLKDFFGARRRAQKAAQLAARTLSDPEQS
HHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDTRTADEIARDERYLRAAMDEARLAEAAGEVPVGAVVVWNDAIIARGHNLPIKSMDPS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEECCCCCCCCCCCCH
AHAEMQALRAAAQVLGNYRMPECELYVTLEPCAMCSGAILHARLRHVVFGASDPKTGAAG
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
SVVNLFEQAQLNHQTTITGGVLADECGQMLKDFFGARRRAQKAAQLAARTLSDPEQS
HHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]